About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
Tractaments combinats per prevenir les lesions o fibrosis hepàtica en malaltia hepàtica crònica/NASH
Tractaments dirigits a cèl·lules sinusoïdals hepàtiques a través de nanopartícules biodegradables
Desenvolupament de models animals experimentals translacionals a la patologia en humans de NASH i malaltia hepàtica per alcohol
Mètodes no invasius per malaltia hepàtica crònica avançada
Hipertensió portal
Serveis o tecnologies rellevants:
Models animals de malaltia hepàtica crònica: PVL; BDL; CCL4; TAA; NAFLD; NASH; MAFLD
Determinació de paràmetres hemodinàmics en models animals: PP; MAP; SMABF; SMAR, PF; IHVR
Aïllament de cèl·lules primàries de fetge: hepatòcits; LSEC; KC; HSC
Tincions histològiques
Cultius cel·lulars
Citometria de flux
Anàlisis de proteïnes: Wb, IIHC, IF, Proteòmica diferencial
Anàlisis d'expressió gènica: RT-qPCR, ISH, Microarrays
Microscòpia confocal i Microscòpia electrònica
Administració de fàrmacs en nanopartícules: Internalizació; direccionament; biodistribució; efectivitat; assaigs MTT y MTD
IP: Maria Nieves Martell Pérez-Alcalde, Joan Genescà Ferrer
Malaltia avançada: hepatitis alcohòlica, cirrosis i malaltia hepàtica crònica per alcohol (cALD)
Salut pública
Insuficiència hepàtica aguda sobre crònica (ACLF)
IP: Meritxell Ventura Cots
Malalties colestàsiques
Complicacions de la cirrosi hepàtica
IP: Victor Manuel Vargas Blasco
Epidemiologia del fetge gras no alcohòlic, biomarcadors i nous tractament
Infeccions malaltia hepàtica avançada
IP: Juan Manuel Pericàs Pulido
IP: Juan Manuel Pericàs Pulido Collaborators: Miriam Izquierdo Sans Funding agency: Instituto de Salud Carlos III Funding: 65000 Reference: CM23/00251 Duration: 02/01/2024 - 01/01/2026
IP: Maria Buti Ferret Collaborators: - Funding agency: Fundación Lilly de Investigación Biomédica Funding: 40000 Reference: F.LILLY/PREMIOS/2023/BUTI Duration: 30/03/2023 - 29/03/2024
IP: Josep Quer Sivila Collaborators: Sira Rodrigo Bosch, Laia Perez Lasarte, Carolina Campos Martinez Funding agency: Fundació Institut de Recerca HUVH Funding: 69188.74 Reference: VPHD/CAROLINA_C Duration: 01/04/2023 - 31/03/2026
IP: Francisco Rodríguez Frias Collaborators: David Tabernero Caellas Funding agency: GILEAD SCIENCES SLU Funding: 49961.71 Reference: GLD22/00080 Duration: 28/02/2023 - 27/02/2025
PMID: 37003442 Journal: JOURNAL OF HEPATOLOGY Year: 2023 Reference: J Hepatol. 2023 Sep;79(3):876-880. doi: 10.1016/j.jhep.2023.03.024. Epub 2023 Mar 30. Impact factor: Publication type: Letter or abstract Authors: Buti, Maria; Izopet, Jacques; Larrue, Helene; Peron, Jean-Marie et al. DOI: 10.1016/j.jhep.2023.03.024
PMID: 37030400 Journal: JOURNAL OF HEPATOLOGY Year: 2023 Reference: J Hepatol. 2023 Aug;79(2):576-580. doi: 10.1016/j.jhep.2023.02.041. Epub 2023 Apr 6. Impact factor: Publication type: Paper in international publication Authors: Aghemo, Alessio; Akarca, Ulus S; Al-Hamoudi, Waleed K; Alalwan, Abduljaleel M; Aleman, Soo; Alghamdi, Abdullah S; Alghamdi, Saad; Aljumah, Abdulrahman A; Altraif, Ibrahim H; Asselah, Tarik et al. DOI: 10.1016/j.jhep.2023.02.041
PMID: 37043974 Journal: Atencion Primaria Year: 2023 Reference: Aten Primaria. 2023 Jun;55(6):102620. doi: 10.1016/j.aprim.2023.102620. Epub 2023 Apr 10. Impact factor: Publication type: Paper in national publication Authors: Augustin, Salvador; Marco Mourino, Andres; Pericas, Juan M; Rivera-Esteban, Jesus; Turu Santigosa, Elisabet et al. DOI: 10.1016/j.aprim.2023.102620
PMID: 37328754 Journal: RESPIRATORY RESEARCH Year: 2023 Reference: Respir Res. 2023 Jun 17;24(1):159. doi: 10.1186/s12931-023-02462-x. Impact factor: Publication type: Paper in international publication Authors: Anon, Jose M; Barbe, Ferran; Barbera, Carmen; Belmonte, Thalia; Benitez, Ivan D; Bermejo-Martin, Jesus F; Bustamante-Munguira, Elena; Caballero, Jesus; Carbonell, Nieves; Ceccato, Adrian et al. DOI: 10.1186/s12931-023-02462-x
PMID: 34842496 Journal: Emerging Microbes & Infections Year: 2022 Reference: Emerg Microbes Infect. 2022 Dec;11(1):172-181. doi: 10.1080/22221751.2021.2011617. Impact factor: 7.163 Publication type: Paper in international publication Authors: Andres, Cristina; Pinana, Maria; Borras-Bermejo, Blanca; Gonzalez-Sanchez, Alejandra; Garcia-Cehic, Damir; Esperalba, Juliana; Rando, Ariadna; Zules-Ona, Ricardo-Gabriel; Campos, Carolina; Codina, Maria Gema et al. DOI: 10.1080/22221751.2021.2011617
PMID: 34989164 Journal: Hepatology Communications Year: 2022 Reference: Hepatol Commun. 2022 Jun;6(6):1392-1402. doi: 10.1002/hep4.1889. Epub 2022 Jan 6. Impact factor: 5.073 Publication type: Paper in international publication Authors: Gratacos-Gines, Jordi; Tellez, Luis; Gomez-Outomuro, Ana; Navascues, Carmen A; Riveiro-Barciela, Mar; Vinuesa, Raquel; Gomez-Camarero, Judith; Garcia-Retortillo, Montserrat; Diaz-Fontenla, Fernando; Salcedo, Magdalena et al. DOI: 10.1002/hep4.1889
PMID: 34554648 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2022 Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5. Impact factor: 8.086 Publication type: Letter or abstract Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al. DOI: 10.1111/ajt.16855
PMID: 34962498 Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY Year: 2022 Reference: Am J Gastroenterol. 2022 Feb 1;117(2):301-310. doi: 10.14309/ajg.0000000000001596. Impact factor: 10.864 Publication type: Paper in international publication Authors: Morales-Arraez, D; Ventura-Cots, M; Altamirano, J; Abraldes, J G; Cruz-Lemini, M; Thursz, M R; Atkinson, S R; Sarin, S K; Kim, W; Chavez-Araujo, R et al. DOI: 10.14309/ajg.0000000000001596
PMID: 34946123 Journal: Microorganisms Year: 2021 Reference: Microorganisms. 2021 Dec 6;9(12). pii: microorganisms9122518. doi: 10.3390/microorganisms9122518. Impact factor: 4.128 Publication type: Review in international publication Authors: Tabernero, David, Rodriguez-Frias, Francisco, Quer, Josep, Rando-Segura, Ariadna, Pumarola, Tomas, Garcia-Garcia, Selene, Cortese, Maria Francesca et al. DOI: 10.3390/microorganisms9122518
PMID: 34887634 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2021 Reference: World J Gastroenterol. 2021 Nov 7;27(41):7144-7158. doi: 10.3748/wjg.v27.i41.7144. Impact factor: 5.742 Publication type: Paper in international publication Authors: Garcia-Garcia, Selene, Cortese, Maria Francesca, Tabernero, David, Gregori, Josep, Vila, Marta, Pacin, Beatriz, Quer, Josep, Casillas, Rosario, Castillo-Ribelles, Laura, Ferrer-Costa, Roser et al. DOI: 10.3748/wjg.v27.i41.7144
PMID: 34865052 Journal: JOURNAL OF INFECTIOUS DISEASES Year: 2021 Reference: J Infect Dis. 2021 Dec 4. pii: 6449510. doi: 10.1093/infdis/jiab589. Impact factor: 5.226 Publication type: Paper in international publication Authors: Rico, Angie, Piron, Maria, Bes, Marta, Sauleda, Silvia, Costafreda, Maria Isabel et al. DOI: 10.1093/infdis/jiab589
PMID: 34828337 Journal: Genes Year: 2021 Reference: Genes (Basel). 2021 Oct 28;12(11). pii: genes12111731. doi: 10.3390/genes12111731. Impact factor: 4.096 Publication type: Paper in international publication Authors: Bilbao, Itxarone, Quer, Josep, Esteban, Juan Ignacio, Perales, Celia, Llorens-Revull, Meritxell, Gregori, Josep, Dopazo, Cristina, Rodriguez-Frias, Francisco, Garcia-Cehic, Damir, Soria, Maria Eugenia et al. DOI: 10.3390/genes12111731
PMID: 32868034 Journal: MEDICINA CLINICA Year: 2020 Reference: Med Clin (Barc). 2020 Dec 24;155(12):541-547. doi: 10.1016/j.medcli.2020.06.057. Epub 2020 Aug 28. Impact factor: 1.635 Publication type: Review in national publication Authors: Trallero-Araguas, Ernesto, Martinez-Valle, Fernando, Roca-Herrera, Maria, Zamora, Ester, Barreira-Diaz, Ana, Munoz-Couselo, Eva, Riveiro-Barciela, Mar et al. DOI: 10.1016/j.medcli.2020.06.057
PMID: 31857134 Journal: ANTIVIRAL RESEARCH Year: 2020 Reference: Antiviral Res. 2020 Feb;174:104694. doi: 10.1016/j.antiviral.2019.104694. Epub 2019 Dec 16. Impact factor: 4.101 Publication type: Paper in international publication Authors: Niubo, Jordi, Chen, Qian, Perales, Celia, Soria, Maria Eugenia, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Buti, Maria, Crespo, Javier, Calleja, Jose Luis et al. DOI: 10.1016/j.antiviral.2019.104694
PMID: 32770818 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 Nov;40(11):2732-2743. doi: 10.1111/liv.14632. Epub 2020 Oct 13. Impact factor: 5.175 Publication type: Paper in international publication Authors: Barbera, Aurora, Raurell, Imma, Garcia-Lezana, Teresa, Torres-Arauz, Manuel, Bravo, Miren, Hide, Diana, Gil, Mar, Salcedo, Maria Teresa, Genesca, Joan, Martell, Maria et al. DOI: 10.1111/liv.14632
PMID: 32752979 Journal: Emerging Microbes & Infections Year: 2020 Reference: Emerg Microbes Infect. 2020 Dec;9(1):1900-1911. doi: 10.1080/22221751.2020.1806735. Impact factor: 5.776 Publication type: Paper in international publication Authors: Almirante, Benito, Esteban, Juan Ignacio, Pumarola, Tomas, Anton, Andres, Quer, Josep, Ferrer, Ricard, Campins, Magda, Martin, Maria Carmen, Quer, Susanna, Andres, Cristina et al. DOI: 10.1080/22221751.2020.1806735
PMID: 31203153 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 Oct;71(4):666-672. doi: 10.1016/j.jhep.2019.06.002. Epub 2019 Jun 14. Impact factor: 18.946 Publication type: Paper in international publication Authors: Marino, Zoe, Torras, Xavier, Luis Calleja, Jose, Antonio Carrion, Jose, Fernandez, Inmaculada, Maria Morillas, Rosa, Miguel Rosales, Jose, Carmona, Isabel, Fernandez-Rodriguez, Conrado, Hernandez-Guerra, Manuel et al. DOI: 10.1016/j.jhep.2019.06.002
PMID: 31118701 Journal: Infection and Drug Resistance Year: 2019 Reference: Infect Drug Resist. 2019 Apr 24;12:947-955. doi: 10.2147/IDR.S195441. eCollection 2019. Impact factor: 3 Publication type: Paper in international publication Authors: von Massow, Georg, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Macia, Maria Dolores, Escarda, Ana, Esteban, Juan Ignacio, Quer, Josep et al. DOI: 10.2147/IDR.S195441
PMID: 30983817 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2019 Reference: World J Gastroenterol. 2019 Apr 7;25(13):1566-1579. doi: 10.3748/wjg.v25.i13.1566. Impact factor: 3.411 Publication type: Paper in international publication Authors: Godoy, Cristina, Tabernero, David, Sopena, Sara, Gregori, Josep, Cortese, Maria Francesca, Gonzalez, Carolina, Casillas, Rosario, Yll, Marcal, Rando, Ariadna, Lopez-Martinez, Rosa et al. DOI: 10.3748/wjg.v25.i13.1566
PMID: 30842623 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Mar 6;9(1):3678. doi: 10.1038/s41598-019-40099-3. Impact factor: 4.011 Publication type: Paper in international publication Authors: Saludes, V, Antuori, A, Reinhardt, B, Viciana, I, Clavijo, E, Schreiber, L, Tenenbaum, M, Rodriguez-Frias, F, Quer, J, Matas, L et al. DOI: 10.1038/s41598-019-40099-3
PMID: 30415162 Journal: Current Opinion in Virology Year: 2018 Reference: Curr Opin Virol. 2018 Oct;32:100-107. doi: 10.1016/j.coviro.2018.10.003. Epub 2018 Nov 8. Impact factor: 5.644 Publication type: Review in national publication Authors: Tabernero, David, Cortese, Maria Francesca, Buti, Maria, Rodriguez-Frias, Francisco et al. DOI: 10.1016/j.coviro.2018.10.003
PMID: 30284732 Journal: TRANSFUSION Year: 2018 Reference: Transfusion. 2018 Nov;58(11):2501-2505. doi: 10.1111/trf.14831. Epub 2018 Oct 4. Impact factor: 3.423 Publication type: Letter or abstract Authors: Riveiro-Barciela, Mar, Bes, Marta, Quer, Josep, Valcarcel, David, Piriz, Sofia, Gregori, Josep, Llorens, Meritxell, Salcedo, Maria-Teresa, Piron, Maria, Esteban, Rafael et al. DOI: 10.1111/trf.14831
PMID: 30223834 Journal: RESPIRATORY RESEARCH Year: 2018 Reference: Respir Res. 2018 Sep 17;19(1):177. doi: 10.1186/s12931-018-0882-0. Impact factor: 3.751 Publication type: Review in international publication Authors: Barrecheguren, Miriam, Gonzalez, Cruz, Miravitlles, Marc et al. DOI: 10.1186/s12931-018-0882-0
PMID: 30176817 Journal: BMC INFECTIOUS DISEASES Year: 2018 Reference: BMC Infect Dis. 2018 Sep 3;18(1):446. doi: 10.1186/s12879-018-3356-6. Impact factor: 2.62 Publication type: Paper in international publication Authors: Domingo, Esteban, Rodriguez-Frias, Francisco, Buti, Maria, Esteban, Rafael, Esteban, Juan Ignacio, Quer, Josep, Perales, Celia, Beach, Nathan M, de Avila, Ana I, Llorens, Meritxell et al. DOI: 10.1186/s12879-018-3356-6
PMID: 28468860 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2017 Reference: J Clin Microbiol. 2017 Jul;55(7):2180-2187. doi: 10.1128/JCM.00169-17. Epub 2017 May 3. Impact factor: 3.712 Publication type: Paper in international publication Authors: Laperche, Syria, Sauleda, Silvia, Piron, Maria, Muhlbacher, Annelies, Schennach, Harald, Queiros, Lucinda, Uno, Naoki, Yanagihara, Katsunori, Imdahl, Roland, Hey, Ariann et al. DOI: 10.1128/JCM.00169-17
PMID: NOPMID003 Journal: ICU Management Year: 2017 Reference: ICU Management & Practice 2017:4 Impact factor: 0 Publication type: Paper in international publication Authors: Ferrer Ricard, Juan Carlos Ruiz-Rodriguez, Larrosa Nieves, Llaneras J, Molas Emma, Juanjo Gonzalez-Lopez et al. DOI:
PMID: 27785789 Journal: TRANSFUSION Year: 2017 Reference: Transfusion. 2017 Feb;57(2):244-247. doi: 10.1111/trf.13876. Epub 2016 Oct 26. Impact factor: 3.042 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Sauleda, Silvia, Quer, Josep, Salvador, Fernando, Gregori, Josep, Piron, Maria, Rodriguez-Frias, Francisco, Buti, Maria et al. DOI: 10.1111/trf.13876
PMID: 29238183 Journal: International Journal of Chronic Obstructive Pulmonary Disease Year: 2017 Reference: Int J Chron Obstruct Pulmon Dis. 2017 Nov 29;12:3381-3390. doi: 10.2147/COPD.S145445. eCollection 2017. Impact factor: 3.157 Publication type: Paper in international publication Authors: Esquinas, Cristina, Janciauskiene, Sabina, Gonzalo, Ricardo, Mas de Xaxars, Gemma, Olejnicka, Beata, Belmonte, Irene, Barrecheguren, Miriam, Rodriguez, Esther, Nunez, Alexa, Rodriguez-Frias, Francisco et al. DOI: 10.2147/COPD.S145445
PMID: 27362848 Journal: PLoS One Year: 2016 Reference: PLoS One. 2016 Jun 30;11(6):e0158557. doi: 10.1371/journal.pone.0158557. eCollection 2016. Impact factor: 3.057 Publication type: Paper in international publication Authors: Ruiz, Alicia, Homs, Maria, Rodriguez-Frias, Francisco, Gregori, Josep, Tabernero, David, Godoy, Cristina, Barakat, Salma, Quer, Josep, Riveiro-Barciela, Mar, Roggendorf, Michael et al. DOI: 10.1371/journal.pone.0158557
PMID: 27343299 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2016 Reference: J Clin Microbiol. 2016 Jul;54(7):1933. doi: 10.1128/JCM.01007-16. Impact factor: 3.631 Publication type: Paper in international publication Authors: Sauleda, Silvia, Bes, Marta, Gomez, Jordi, Briones, Carlos, Perales, Celia, Sheldon, Julie, Castells, Lluis, Viladomiu, Lluis, Salmeron, Javier, Ruiz-Extremera, Angela et al. DOI: 10.1128/JCM.01007-16
PMID: 26154193 Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE Year: 2016 Reference: Clin Chem Lab Med. 2016 Feb;54(2):241-8. doi: 10.1515/cclm-2015-0297. Impact factor: 3.017 Publication type: Paper in international publication Authors: Belmonte, Irene, Montoto, Luciana, Miravitlles, Marc, Barrecheguren, Miriam, Esquinas, Cristina, Rodriguez, Esther, Giralt, Marina, Rodriguez-Frias, Francisco et al. DOI: 10.1515/cclm-2015-0297
PMID: 27060566 Journal: VIROLOGY Year: 2016 Reference: Virology. 2016 Jun;493:227-37. doi: 10.1016/j.virol.2016.03.017. Epub 2016 Apr 6. Impact factor: 3.2 Publication type: Paper in international publication Authors: Domingo, Esteban, Quer, Josep, Gregori, Josep, Perales, Celia, Rodriguez-Frias, Francisco, Esteban, Juan I et al. DOI: 10.1016/j.virol.2016.03.017
PMID: 25641570 Journal: Transplant Infectious Disease Year: 2015 Reference: Transpl Infect Dis. 2015 Apr;17(2):208-20. doi: 10.1111/tid.12360. Impact factor: 2.064 Publication type: Paper in international publication Authors: Buti, M, Tabernero, D, Mas, A, Homs, M, Prieto, M, Rodriguez-Frias, F, Casafont, F, Casillas, R, Gonzalez, A, Miras, M et al. DOI: 10.1111/tid.12360
PMID: 25967352 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2015 Reference: J Viral Hepat. 2015 Sep;22(9):683-90. doi: 10.1111/jvh.12419. Epub 2015 May 13. Impact factor: 3.909 Publication type: Paper in international publication Authors: Buti, M, Llaneras, J, Riveiro-Barciela, M, Esteban, R et al. DOI: 10.1111/jvh.12419
PMID: 26071338 Journal: JOURNAL OF CLINICAL VIROLOGY Year: 2015 Reference: J Clin Virol. 2015 Jul;68:61-8. doi: 10.1016/j.jcv.2015.05.002. Epub 2015 May 8. Impact factor: 3.016 Publication type: Paper in international publication Authors: Buti, Maria, Casillas, Rosario, Riveiro-Barciela, Mar, Homs, Maria, Tabernero, David, Salcedo, Maria Teresa, Rodriguez-Frias, Francisco, Esteban, Rafael et al. DOI: 10.1016/j.jcv.2015.05.002
PMID: 25027067 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2015 Reference: Arch Bronconeumol. 2015 Apr;51(4):185-92. doi: 10.1016/j.arbres.2014.05.008. Epub 2014 Jul 12. Impact factor: 1.823 Publication type: Paper in national publication Authors: Casas, Francisco, Blanco, Ignacio, Martinez, Maria Teresa, Bustamante, Ana, Miravitlles, Marc, Cadenas, Sergio, Hernandez, Jose M, Lazaro, Lourdes, Rodriguez, Esther, Rodriguez-Frias, Francisco et al. DOI: 10.1016/j.arbres.2014.05.008
PMID: 25393280 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Nov 13;9(11):e112306. doi: 10.1371/journal.pone.0112306. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Homs, Maria, Caballero, Andrea, Gregori, Josep, Tabernero, David, Quer, Josep, Nieto, Leonardo, Esteban, Rafael, Buti, Maria, Rodriguez-Frias, Francisco et al. DOI: 10.1371/journal.pone.0112306
PMID: 25068388 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Jul 28;9(7):e103028. doi: 10.1371/journal.pone.0103028. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Buti, Maria, Homs, Maria, Campos-Varela, Isabel, Cantarell, Carmen, Crespo, Manuel, Castells, Lluis, Tabernero, David, Quer, Josep, Esteban, Rafael et al. DOI: 10.1371/journal.pone.0103028
PMID: 24134179 Journal: LIVER INT Year: 2014 Reference: Liver Int. 2014 Jul;34(6):896-906. doi: 10.1111/liv.12362. Epub 2013 Nov 20. Impact factor: 4.447 Publication type: Paper in international publication Authors: Domingo, Esteban, Cubero, Maria, Gregori, Josep, Esteban, Juan I, Garcia-Cehic, Damir, Bes, Marta, Perales, Celia, Casillas, Rosario, Sanchez, Alex, Ortega, Israel et al. DOI: 10.1111/liv.12362
PMID: 23907754 Journal: HEPATOLOGY Year: 2014 Reference: Hepatology. 2014 Mar;59(3):1210-2. doi: 10.1002/hep.26647. Epub 2014 Jan 13. Impact factor: 11.19 Publication type: Letter whit IF Authors: Rodriguez-Frias, Francisco, Tabernero, David, Esteban, Rafael, Buti, Maria et al. DOI: 10.1002/hep.26647
PMID: 23523552 Journal: ANTIVIRAL RESEARCH Year: 2013 Reference: Antiviral Res. 2013 May;98(2):273-83. doi: 10.1016/j.antiviral.2013.03.007. Epub 2013 Mar 20. Impact factor: 3.925 Publication type: Paper in international publication Authors: Ramirez, Clara, Gregori, Josep, Tabernero, David, Camos, Silvia, Casillas, Rosario, Quer, Josep, Esteban, Rafael, Homs, Maria, Rodriguez-Frias, Francisco, Buti, Maria et al. DOI: 10.1016/j.antiviral.2013.03.007
PMID: 23332972 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2013 Reference: Enferm Infecc Microbiol Clin. 2013 Aug-Sep;31(7):491-2. doi: 10.1016/j.eimc.2012.11.016. Epub 2013 Jan 17. Impact factor: 1.478 Publication type: Letter whit IF Authors: Piron, Maria, Alegre, Jose, Ribera, Esteban, Sauleda, Silvia et al. DOI: 10.1016/j.eimc.2012.11.016
PMID: 22173156 Journal: JOURNAL OF HEPATOLOGY Year: 2012 Reference: J Hepatol. 2012 Apr;56(4):765-74. Epub 2011 Dec 13. Impact factor: 9.264 Publication type: Paper in international publication Authors: Bes, Marta, Vargas, Victor, Piron, Maria, Casamitjana, Natalia, Esteban, Juan Ignacio, Vilanova, Nuria, Pinacho, Asuncion, Quer, Josep, Puig, Lluis, Guardia, Jaime et al. DOI: 10.1016/j.jhep.2011.11.011
PMID: 22666402 Journal: PLoS One Year: 2012 Reference: PLoS One. 2012;7(5):e37874. doi: 10.1371/journal.pone.0037874. Epub 2012 May 30. Impact factor: 4.092 Publication type: Paper in international publication Authors: Esteban, Juan I, Rodriguez-Frias, Francisco, Tabernero, David, Quer, Josep, Cubero, Maria, Camos, Silvia, Ferrer-Costa, Carles, Sanchez, Alex, Jardi, Rosendo, Schaper, Melanie et al. DOI: 10.1371/journal.pone.0037874
PMID: 22608490 Journal: Gastroenterologia y Hepatologia Year: 2012 Reference: Gastroenterol Hepatol. 2012 Dec;35(10):719-24. doi: 10.1016/j.gastrohep.2012.03.003. Epub 2012 May 17. Impact factor: 0.727 Publication type: Paper in national publication Authors: , , et al. DOI: 10.1016/j.gastrohep.2012.03.003
PMID: 21719049 Journal: MEDICINA CLINICA Year: 2012 Reference: Med Clin (Barc). 2012 Apr 28;138(11):483-8. Epub 2011 Jun 29. Impact factor: 1.385 Publication type: Review in national publication Authors: Buti Ferret, Maria, Rodríguez Frias, Francisco, Esteban Mur, Rafael et al. DOI: 10.1016/j.medcli.2011.04.024
PMID: 21618698 Journal: LIVER TRANSPLANTATION Year: 2011 Reference: Liver Transpl. 2011 Nov;17(11):1304-8. doi: 10.1002/lt.22346. Impact factor: 3.068 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1002/lt.22346
PMID: 21470755 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2011 Reference: Arch Bronconeumol. 2011 Aug;47(8):415-7. Epub 2011 Apr 5. Impact factor: Publication type: Letter or abstract Authors: , , , , , et al. DOI: 10.1016/j.arbres.2011.02.005
PMID: 21502680 Journal: Annals of Hepatology Year: 2011 Reference: Ann Hepatol. 2011 Apr 1;10(2):180-7. Impact factor: 1.867 Publication type: Paper in international publication Authors: Esteban, Rafael, Guardia, Jaime, Campos-Varela, Isabel, Castells, Lluis, Buti, Maria, Vargas, Victor, Bilbao, Itxarone, Rodriguez-Frias, Francisco, Jardi, Rosendo, Charco, Ramon et al. DOI:
PMID: 21311107 Journal: ANTIVIRAL THERAPY Year: 2011 Reference: Antivir Ther. 2011;16(1):37-49. Impact factor: 3.774 Publication type: Paper in international publication Authors: Fernandez-Fernandez, Pilar, Quer, Josep, Esteban, Rafael, Rodriguez-Frias, Francisco, Tabernero, David, Schaper, Melanie, Jardi, Rosendo, Homs, Maria, Buti, Maria et al. DOI: 10.3851/IMP1701
PMID: 20374224 Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS Year: 2010 Reference: Aliment Pharmacol Ther. 2010 Jul;32(1):97-104. Epub 2010 Mar 31. Impact factor: 4.357 Publication type: Paper in international publication Authors: , , , , , , , et al. DOI: 10.1111/j.1365-2036.2010.04319.x
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PhD student: Jesus Manuel Rivera Esteban Director/s: Salvador Augustin Recio University: Year: 2023
Preliminary study results confirm that the drug resmetirom reduces the presence of fat, inflammation, cell damage and fibrosis in the liver.
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
The research team used nanotechnology to deliver the drug directly to liver cells, which eliminated side effects without reducing effectiveness.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
