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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Team

Cusidó Sabidó, Maria de la Serra

Cusidó Sabidó, Maria de la Serra

Predoctoral researcher
Liver Diseases
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Elena Vargas Accarino

Elena Vargas Accarino

Postdoctoral researcher
Liver Diseases
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Marcella Salzano

Marcella Salzano

Research technician
Liver Diseases
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Maria Martínez Gómez

Maria Martínez Gómez

Research technician
Liver Diseases
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Marta Ibañez Lligoña

Marta Ibañez Lligoña

Predoctoral researcher
Liver Diseases
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Sonia Carramiñana Mayor

Sonia Carramiñana Mayor

Research technician
Liver Diseases
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Cusidó Sabidó, Maria de la Serra

Cusidó Sabidó, Maria de la Serra

Predoctoral researcher
Liver Diseases
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Elena Vargas Accarino

Elena Vargas Accarino

Postdoctoral researcher
Liver Diseases
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Marcella Salzano

Marcella Salzano

Research technician
Liver Diseases
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Maria Martínez Gómez

Maria Martínez Gómez

Research technician
Liver Diseases
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Marta Ibañez Lligoña

Marta Ibañez Lligoña

Predoctoral researcher
Liver Diseases
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Sonia Carramiñana Mayor

Sonia Carramiñana Mayor

Research technician
Liver Diseases
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Research lines

Transplantament hepàtic

Sarcopènia i fragilitat

Malaltia metabòlica i NASH pre-transplantament

Nutrició en el trasplantament


Serveis o tecnologies rellevants:


Bioimpedància

IP: Isabel Campos Varela

Projects

FPU 2021

IP: Josep Quer Sivila
Collaborators: Sergi Colomer Castell
Funding agency: Ministerio de Universidades
Funding: 73389.26
Reference: FPU21/04150
Duration: 16/12/2022 - 15/05/2025

Malalties hepàtiques

IP: Joan Genescà Ferrer
Collaborators: Beatriz Minguez Rosique, Sergi Colomer Castell, Elena Vargas Accarino, Immaculada Raurell Saborit, Lluís Viladomiu Catà, Lluis Castells Fusté, Maria del Mar Riveiro Barciela, Maria Buti Ferret, Montserrat Gomez Perez, Judit Romero Vico, Josep Quer Sivila, Adriana Palom Agusti, Juan Manuel Pericàs Pulido, Maria Nieves Martell Pérez-Alcalde, Damir Garcia Cehic, Malalties hepàtiques, Laura Puente Ramo, Isabel Campos Varela, María Bermúdez Ramos, Juan Ignacio Esteban Mur, Ester Palacio Gutierrez, Susana Anton Calvo, Monica Higuera Urbano, Meritxell Ventura Cots, Ares Aurora Villagrasa Vilella, Emma Bigas Alsina, Carolina Campos Martinez, Macarena Simon-Talero Horga, David Tabernero Caellas, Mònica Pons Delgado, Marcella Salzano
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00462
Duration: 01/01/2022 - 30/06/2025

Estudio de quasispecies por metagenómica en neuropatías asociadas a virus por secuenciación masiva de nueva generación.

IP: Josep Quer Sivila
Collaborators: Sergi Colomer Castell, Marta Ibañez Lligoña, Lluís Viladomiu Catà, Damir Garcia Cehic, Maria Piñana Moro, Pablo Gabriel Medina, Arnau Llauradó Gayete, Carolina Campos Martinez, Alejandra Gonzalez Sánchez
Funding agency: Instituto de Salud Carlos III
Funding: 292820
Reference: PI22/00258
Duration: 01/01/2023 - 31/12/2025

Caracterización de las claves fisiopatológicas y fenotipos de la enfermedad del hígado graso metabólica con ingesta moderada de alcohol para identificar nuevas terapias (ReLiveR).

IP: Meritxell Ventura Cots
Collaborators: Immaculada Raurell Saborit, Juan Manuel Pericàs Pulido, Laura Puente Ramo, Ares Aurora Villagrasa Vilella, Juan Bañares Sanchez, Maria de la Serra Cusidó Sabidó, Maria Martínez Gómez
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI22/01770
Duration: 01/01/2023 - 31/12/2025

Publications

Pandemic preparedness beyond COVID-19: what we know, what we do, and what we don't.

PMID: 38461941
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2024
Reference: Clin Microbiol Infect. 2024 Mar 8:S1198-743X(24)00119-8. doi: 10.1016/j.cmi.2024.03.007.
Impact factor:
Publication type: Editorail in international publication
Authors: Pericas, Juan M et al.
DOI: 10.1016/j.cmi.2024.03.007

Editorial: Liver elastography for chronic hepatitis D-the end of liver biopsy?

PMID: 38462685
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2024
Reference: Aliment Pharmacol Ther. 2024 Apr;59(7):898-899. doi: 10.1111/apt.17890.
Impact factor:
Publication type: Editorail in international publication
Authors: Buti, Maria; Palom, Adriana; Riveiro-Barciela, Mar et al.
DOI: 10.1111/apt.17890

Post-treatment LSM rather than change during treatment predicts decompensation in patients with cACLD after HCV cure.

PMID: 38521170
Journal: JOURNAL OF HEPATOLOGY
Year: 2024
Reference: J Hepatol. 2024 Mar 21:S0168-8278(24)00198-3. doi: 10.1016/j.jhep.2024.03.015.
Impact factor:
Publication type: Paper in international publication
Authors: Ahumada, Adriana; Alonso Lopez, Sonia; Azzaroli, Francesco; Banares, Rafael; Benjamin Mauz, Jim; Burghart, Lukas; Casanova-Cabral, Michelle; Dajti, Elton; Ecker, Dominik; Forns, Xavier et al.
DOI: 10.1016/j.jhep.2024.03.015

Genomic evolution of human respiratory syncytial virus during a decade (2013-2023): bridging the path to monoclonal antibody surveillance.

PMID: 38588960
Journal: JOURNAL OF INFECTION
Year: 2024
Reference: J Infect. 2024 Apr 6:106153. doi: 10.1016/j.jinf.2024.106153.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Cristina; Anton, Andres; Arnedo-Munoz, Maria; Creus-Costa, Anna; Esperalba, Juliana; Gonzalez-Lopez, Juan Jose; Gonzalez-Sanchez, Alejandra; Larrosa, Nieves; Martinez-Urtaza, Jaime; Nadal-Baron, Patricia et al.
DOI: 10.1016/j.jinf.2024.106153

Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg-positive chronic hepatitis B.

PMID: 36427857
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2023
Reference: Aliment Pharmacol Ther. 2023 Mar;57(5):509-523. doi: 10.1111/apt.17299. Epub 2022 Nov 25.
Impact factor:
Publication type: Paper in international publication
Authors: Aeschbacher, Thomas; Buti Ferret, Maria; Feierbach, Becket; Gaggar, Anuj; Gane, Ed; Jackson, Kathy; Janssen, Harry L A; Littlejohn, Margaret; Marcellin, Patrick; Martin, Ross et al.
DOI: 10.1111/apt.17299

Prediction of clinical events by liver stiffness and chronic kidney disease by NAFLD in patients with type-2 diabetes.

PMID: 36435379
Journal: Gastroenterologia y Hepatologia
Year: 2023
Reference: Gastroenterol Hepatol. 2023 Nov;46(9):682-691. doi: 10.1016/j.gastrohep.2022.11.001. Epub 2022 Nov 23.
Impact factor:
Publication type: Paper in national publication
Authors: Augustin, Salvador; Baneras, Jordi; Boixadera, Anna; Ferreira-Gonzalez, Ignacio; Genesca, Joan; Hernandez, Cristina; Manzano-Nunez, Ramiro; Pericas, Juan M; Planas, Alejandra; Pons, Monica et al.
DOI: 10.1016/j.gastrohep.2022.11.001

Clinical practice guidelines of the Catalan Society of Gastroenterology about hepatic elastography 2022.

PMID: 36435378
Journal: Gastroenterologia y Hepatologia
Year: 2023
Reference: Gastroenterol Hepatol. 2023 Nov;46(9):732-746. doi: 10.1016/j.gastrohep.2022.11.005. Epub 2022 Nov 23.
Impact factor:
Publication type: Paper in national publication
Authors: Amador, A; Bartres, M C; Carrion, J A; Fernandez, R; Forns, X; Genesca, J; Gines, P; Graupera, I; Monllor, T; Morillas, R M et al.
DOI: 10.1016/j.gastrohep.2022.11.005

NAFLD as the metabolic hallmark of obesity.

PMID: 36357606
Journal: Internal and Emergency Medicine
Year: 2023
Reference: Intern Emerg Med. 2023 Jan;18(1):31-41. doi: 10.1007/s11739-022-03139-x. Epub 2022 Nov 10.
Impact factor:
Publication type: Review in international publication
Authors: Ciudin, Andreea; Manzano-Nunez, Ramiro; Pericas, Juan M; Rojano, Alba; Sena, Elena et al.
DOI: 10.1007/s11739-022-03139-x

ACE Score Identifies HBeAg-negative Inactive Carriers at a Single-point Evaluation, Regardless of HBV Genotype.

PMID: 36381089
Journal: Journal of Clinical and Translational Hepatology
Year: 2022
Reference: J Clin Transl Hepatol. 2022 Dec 28;10(6):1068-1076. doi: 10.14218/JCTH.2022.00068. Epub 2022 Apr 24.
Impact factor:
Publication type: Paper in international publication
Authors: Bes, Marta; Buti, Maria; Casillas, Rosario; Esteban, Rafael; Palom, Adriana; Rando, Ariadna; Riveiro-Barciela, Mar; Roade, Luisa; Rodriguez-Frias, Francisco; Salcedo, Maria Teresa et al.
DOI: 10.14218/JCTH.2022.00068

Forty-Year Trends in Cardiac Implantable Electronic Device Infective Endocarditis.

PMID: 36381626
Journal: Open Forum Infectious Diseases
Year: 2022
Reference: Open Forum Infect Dis. 2022 Oct 14;9(11):ofac547. doi: 10.1093/ofid/ofac547. eCollection 2022 Nov.
Impact factor:
Publication type: Paper in international publication
Authors: Almela, Manel; Cuervo, Guillermo; Falces, Carlos; Garcia de la Maria, Cristina; Hernandez-Meneses, Marta; Llopis, Jaume; Marco, Francesc; Mestres, Carlos A; Miro, Jose M; Moreno, Asuncion et al.
DOI: 10.1093/ofid/ofac547

Viral hepatitis elimination: Towards a hepatitis-free world.

PMID: 35907517
Journal: JOURNAL OF HEPATOLOGY
Year: 2022
Reference: J Hepatol. 2022 Nov;77(5):1444-1447. doi: 10.1016/j.jhep.2022.06.034. Epub 2022 Jul 27.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Craxi, Antonio; Foster, Graham R; Maticic, Mojca; Negro, Francesco; Zeuzem, Stefan; Zoulim, Fabien et al.
DOI: 10.1016/j.jhep.2022.06.034

Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper.

PMID: 35868584
Journal: JOURNAL OF HEPATOLOGY
Year: 2022
Reference: J Hepatol. 2022 Oct;77(4):1161-1197. doi: 10.1016/j.jhep.2022.07.008. Epub 2022 Jul 20.
Impact factor:
Publication type: Paper in international publication
Authors: Belli, Luca S; Berenguer, Marina; Berg, Thomas; Boettler, Tobias; Buti, Maria; Cornberg, Markus; Eberhardt, Christiane S; Jalan, Rajiv; Marjot, Thomas; Mondelli, Mario U et al.
DOI: 10.1016/j.jhep.2022.07.008

Late presentation of chronic HBV and HCV patients seeking first time specialist care in Spain: a 2-year registry review.

PMID: 34921156
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Dec 17;11(1):24133. doi: 10.1038/s41598-021-01885-0.
Impact factor:
Publication type: Paper in international publication
Authors: Andrade, Raul J; Arenas, Juan; Buti, Maria; Calleja, Jose Luis; Crespo, Javier; Garcia-Samaniego, Javier; Gomez, Alexandra; Hernandez-Guerra, Manuel; Lazarus, Jeffrey V; Lens, Sabela et al.
DOI: 10.1038/s41598-021-01885-0

Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA: Different quasispecies?

PMID: 34887634
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2021
Reference: World J Gastroenterol. 2021 Nov 7;27(41):7144-7158. doi: 10.3748/wjg.v27.i41.7144.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Casillas, Rosario; Casis, Ernesto; Castillo-Ribelles, Laura; Cortese, Maria Francesca; Esteban, Rafael; Ferrer-Costa, Roser; Garcia-Garcia, Selene; Gregori, Josep; Pacin, Beatriz et al.
DOI: 10.3748/wjg.v27.i41.7144

COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter?

PMID: 34830495
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 9;10(22). pii: jcm10225213. doi: 10.3390/jcm10225213.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Anton, Andres; Aznar, Maria Luisa; Bosch-Nicolau, Pau; Campos-Varela, Isabel; Espinosa-Pereiro, Juan; Guillen-Del-Castillo, Alfredo; Leguizamo-Martinez, Lina Maria; Miarons, Marta; Monforte, Arnau et al.
DOI: 10.3390/jcm10225213

Study of Quasispecies Complexity and Liver Damage Progression after Liver Transplantation in Hepatitis C Virus Infected Patients.

PMID: 34828337
Journal: Genes
Year: 2021
Reference: Genes (Basel). 2021 Oct 28;12(11). pii: genes12111731. doi: 10.3390/genes12111731.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, Itxarone; Chen, Qian; Dopazo, Cristina; Esteban, Juan Ignacio; Garcia-Cehic, Damir; Gregori, Josep; Llorens-Revull, Meritxell; Perales, Celia; Quer, Josep; Rando, Ariadna et al.
DOI: 10.3390/genes12111731

Does retraction after misconduct have an impact on citations? A pre-post study.

PMID: 33187964
Journal: BMJ Global Health
Year: 2020
Reference: BMJ Glob Health. 2020 Nov;5(11). pii: bmjgh-2020-003719. doi: 10.1136/bmjgh-2020-003719.
Impact factor:
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel; Candal-Pedreira, Cristina; Fernandez, Esteve; Perez-Rios, Monica; Ramos, Jorge; Ruano-Ravina, Alberto et al.
DOI: 10.1136/bmjgh-2020-003719

High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients.

PMID: 33166788
Journal: EBioMedicine
Year: 2020
Reference: EBioMedicine. 2020 Dec;62:103077. doi: 10.1016/j.ebiom.2020.103077. Epub 2020 Nov 6.
Impact factor:
Publication type: Paper in international publication
Authors: Alba, Veronica; Ceausu, Andra; Domingo, Pere; Falco, Vicenc; Inciarte, Alexy; Mallolas, Josep; Marti, Anna; Masip, Jenifer; Pacheco, Yolanda Maria; Peraire, Joaquim et al.
DOI: 10.1016/j.ebiom.2020.103077

Treatment with tenofovir disoproxil fumarate or entecavir in chronic hepatitis B virus-infected patients with renal impairment: results from a 7-year, multicentre retrospective cohort study.

PMID: 32583915
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2020
Reference: Aliment Pharmacol Ther. 2020 Aug;52(3):500-512. doi: 10.1111/apt.15901. Epub 2020 Jun 25.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, K; Andrade, R; Andreone, P; Antoni, C; Aoufi Rabih, S; Aspinall, R; Berg, T; Berg, Thomas; Botros, Irina; Bourliere, M et al.
DOI: 10.1111/apt.15901

Very low probability of significant liver inflammation in chronic hepatitis B patients with low ALT levels in the absence of liver fibrosis.

PMID: 32886813
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2020
Reference: Aliment Pharmacol Ther. 2020 Oct;52(8):1399-1406. doi: 10.1111/apt.16067. Epub 2020 Sep 4.
Impact factor:
Publication type: Paper in international publication
Authors: Brouwer, Willem P; Buti, Maria; Chan, Henry L-Y; Chien, Rong-Nan; Choi, Hannah; de Knegt, Robert J; de Man, Robert A; Gaggar, Anuj; Hansen, Bettina E; Janssen, Harry L A et al.
DOI: 10.1111/apt.16067

Significant Improvement in Diagnosis of Hepatitis C Virus Infection by One Step Strategy in a Central Laboratory: An Optimal Tool for Hepatitis C Elimination?

PMID: 31694971
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2019
Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01815-19. doi: 10.1128/JCM.01815-19. Print 2019 Dec 23.
Impact factor:
Publication type: Paper in international publication
Authors: Arias-Garcia, Andrea; Blanco-Grau, Albert; Buti-Ferret, Maria; Caballero-Garralda, Andrea; Casis-Saez, Ernesto; Castellote-Belles, Laura; Esteban-Mur, Rafael; Ferrer-Costa, Roser; Lopez-Martinez, Rosa; Montserrat-Lloan, Isabel et al.
DOI: 10.1128/JCM.01815-19

Viral load measurements in individuals with hepatitis C infection: On the EASL Recommendations on Treatment of Hepatitis C 2018.

PMID: 31666360
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2019
Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01379-19. doi: 10.1128/JCM.01379-19. Print 2019 Dec 23.
Impact factor:
Publication type: Letter or abstract
Authors: Buti, Maria; Lopez-Martinez, Rosa; Quer, Josep; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco et al.
DOI: 10.1128/JCM.01379-19

IL-7/IL-7R gene variants impact circulating IL-7/IL-7R homeostasis and ART-associated immune recovery status.

PMID: 31673011
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Oct 31;9(1):15722. doi: 10.1038/s41598-019-52025-8.
Impact factor:
Publication type: Paper in international publication
Authors: Alba, Veronica; Castellano, Alfonso J; Ceausu, Andra; Domingo, Pere; Lopez-Dupla, Miguel; Mallolas, Josep; Pacheco, Yolanda Maria; Peraire, Joaquim; Peraire, Maria; Perpinan, Carles et al.
DOI: 10.1038/s41598-019-52025-8

Elimination of hepatitis C. Positioning document of the Spanish Association for the Study of the Liver (AEEH).

PMID: 31657609
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2019
Reference: Rev Esp Enferm Dig. 2019 Nov;111(11):862-873. doi: 10.17235/reed.2019.6700/2019.
Impact factor:
Publication type: Paper in international publication
Authors: Acin, Enrique; Albillos, Albillos; Berenguer, Juan; Berenguer, Marina; Buti, Maria; Calleja, Jose Luis; Colom, Joan; Crespo Garcia, Javier; Fernandez Rodriguez, Conrado; Fernandez, Inmaculada et al.
DOI: 10.17235/reed.2019.6700/2019

HDV evolution-will viral resistance be an issue in HDV infection?

PMID: 30415162
Journal: Current Opinion in Virology
Year: 2018
Reference: Curr Opin Virol. 2018 Oct;32:100-107. doi: 10.1016/j.coviro.2018.10.003. Epub 2018 Nov 8.
Impact factor:
Publication type: Review in national publication
Authors: Buti, Maria; Cortese, Maria Francesca; Rodriguez-Frias, Francisco; Tabernero, David et al.
DOI: 10.1016/j.coviro.2018.10.003

Thrombotic thrombocytopenic purpura relapse induced by acute hepatitis E transmitted by cryosupernatant plasma and successfully controlled with ribavirin.

PMID: 30284732
Journal: TRANSFUSION
Year: 2018
Reference: Transfusion. 2018 Nov;58(11):2501-2505. doi: 10.1111/trf.14831. Epub 2018 Oct 4.
Impact factor:
Publication type: Letter or abstract
Authors: Bes, Marta; Buti, Maria; Esteban, Rafael; Gregori, Josep; Llorens, Meritxell; Piriz, Sofia; Piron, Maria; Quer, Josep; Riveiro-Barciela, Mar; Salcedo, Maria-Teresa et al.
DOI: 10.1111/trf.14831

Rare haplotype load as marker for lethal mutagenesis.

PMID: 30281674
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Oct 3;13(10):e0204877. doi: 10.1371/journal.pone.0204877. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Domingo, Esteban; Esteban, Juan Ignacio; Gallego, Isabel; Gregori, Josep; Guerrero-Murillo, Mercedes; Perales, Celia; Quer, Josep; Soria, Maria Eugenia et al.
DOI: 10.1371/journal.pone.0204877

Guidelines on treatment of hepatitis C virus infection. Spanish Association for the Study of the Liver (AEEH).

PMID: 30270150
Journal: Gastroenterologia y Hepatologia
Year: 2018
Reference: Gastroenterol Hepatol. 2018 Nov;41(9):597-608. doi: 10.1016/j.gastrohep.2018.07.010. Epub 2018 Sep 27.
Impact factor:
Publication type: Clinical guide
Authors: Berenguer, Marina; Buti, Maria; Calleja, Jose L; Carrion, Jose A; Coste, Pablo; Fernandez, Inmaculada; Forns, Xavier; Garcia Deltoro, Miguel; Garcia, Federico; Granados, Rafael et al.
DOI: 10.1016/j.gastrohep.2018.07.010

Left pleural effusion secondary to splenic infarctions in a patient with liver cirrhosis.

PMID: 27939683
Journal: MEDICINA CLINICA
Year: 2017
Reference: Med Clin (Barc). 2017 Feb 9;148(3):144-145. doi: 10.1016/j.medcli.2016.09.048. Epub 2016 Dec 6.
Impact factor:
Publication type: Paper in national publication
Authors: Castells, Lluis; Riveiro-Barciela, Mar; Vidal-Gonzalez, Judit et al.
DOI: 10.1016/j.medcli.2016.09.048

Effectiveness and safety of ombitasvir, paritaprevir, ritonavir +/- dasabuvir +/- ribavirin: An early access programme for Spanish patients with genotype 1/4 chronic hepatitis C virus infection.

PMID: 27976491
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2017
Reference: J Viral Hepat. 2017 Mar;24(3):226-237. doi: 10.1111/jvh.12637. Epub 2016 Dec 15.
Impact factor:
Publication type: Paper in international publication
Authors: Albujar, Alicia Hernandez; Alonso, Maria Rosario Gonzalez; Ampuero, Javier; Anton, Maria Dolores; Arenas, J; Bellot, Pablo; Calleja, J L; Carrion, J A; Cena, Gloria; Comas, Carmen et al.
DOI: 10.1111/jvh.12637

A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis.

PMID: 27922027
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2017
Reference: Am J Gastroenterol. 2017 Feb;112(2):306-315. doi: 10.1038/ajg.2016.539. Epub 2016 Dec 6.
Impact factor:
Publication type: Paper in international publication
Authors: Altamirano, Jose; Bataller, Ramon; Becerra-Martins-de-Oliveira, Bernardo; Caballeria, Juan; Chavez-Araujo, Roberta; de Lourdes Candolo-Martinelli, Ana; Duarte-Rojo, Andres; Duvoor, Chitharanjan; Fernandez-de-Almeida, Simony; Garcia-Saenz-de-Sicilia, Mauricio et al.
DOI: 10.1038/ajg.2016.539

Interferon-free therapies for Patients with Chronic Hepatitis C Genotype 3 Infection: A Systematic Review.

PMID: 27925386
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2017
Reference: J Viral Hepat. 2017 Nov;24(11):904-916. doi: 10.1111/jvh.12660. Epub 2017 Jan 23.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Esteban, Rafael; Gimeno-Ballester, Vicente; Riveiro, Mar; San Miguel, Ramon et al.
DOI: 10.1111/jvh.12660

Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial.

PMID: 28404092
Journal: The lancet. Gastroenterology & hepatology
Year: 2016
Reference: Lancet Gastroenterol Hepatol. 2016 Nov;1(3):196-206. doi: 10.1016/S2468-1253(16)30107-8. Epub 2016 Sep 22.
Impact factor:
Publication type: Paper in international publication
Authors: Acharya, Subrat K; Brunetto, Maurizia; Buti, Maria; Cathcart, Andrea L; Chan, Henry L Y; Chuang, Wan-Long; Flaherty, John F; Gaggar, Anuj; Gane, Edward; Hui, Aric-Josun et al.
DOI: 10.1016/S2468-1253(16)30107-8

Patient experience in HCV therapy: what really matters.

PMID: 28404078
Journal: The lancet. Gastroenterology & hepatology
Year: 2016
Reference: Lancet Gastroenterol Hepatol. 2016 Oct;1(2):90-92. doi: 10.1016/S2468-1253(16)30020-6. Epub 2016 Aug 3.
Impact factor:
Publication type: Letter or abstract
Authors: Buti, Maria; Esteban, Rafael et al.
DOI: 10.1016/S2468-1253(16)30020-6

Esophageal balloon tamponade Vs esophageal stent in controlling acute refractory variceal bleeding: A multicenter RCT.

PMID: 26600191
Journal: HEPATOLOGY
Year: 2016
Reference: Hepatology. 2016 Jun;63(6):1957-67. doi: 10.1002/hep.28360. Epub 2016 Jan 14.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, Juan G; Albillos, Agustin; Alvarado, Edilmar; Augustin, Salvador; Banares, Rafael; Berzigotti, Annalisa; Boix, Jaume; Bosch, Jaime; Calleja, Jose L; Cardenas, Andres et al.
DOI: 10.1002/hep.28360

Impact of eradicating hepatitis C virus on the work productivity of chronic hepatitis C (CH-C) patients: an economic model from five European countries.

PMID: 26482680
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2016
Reference: J Viral Hepat. 2016 Mar;23(3):217-26. doi: 10.1111/jvh.12483. Epub 2015 Oct 20.
Impact factor:
Publication type: Paper in international publication
Authors: Beckerman, R; Brown, A; Buti, M; Fagiuoli, S; Mauss, S; Rosenberg, W; Serfaty, L; Smith, N; Srivastava, A; Stepanova, M et al.
DOI: 10.1111/jvh.12483

Acute Antibody-Mediated Rejection as Cause of Late Liver Allograft Failure: A Case Report.

PMID: 26707330
Journal: TRANSPL P
Year: 2015
Reference: Transplant Proc. 2015 Dec;47(10):3016-9. doi: 10.1016/j.transproceed.2015.10.036.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, I; Caralt, M; Castells, L; Charco, R; Dopazo, C; Lazaro, J L; Montero, A; Salcedo, M T; Sapisochin, G; Vellalta, G et al.
DOI: 10.1016/j.transproceed.2015.10.036

Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.

PMID: 26395289
Journal: J GEN VIROL
Year: 2015
Reference: J Gen Virol. 2015 Dec;96(12):3493-3498. doi: 10.1099/jgv.0.000289.
Impact factor:
Publication type: Paper in international publication
Authors: Casillas, Rosario; Domingo, Esteban; Esteban, Juan I; Forns, Xavier; Garcia-Cehic, Damir; Gonzalez, Patricia; Gregori, Josep; Perez-Del-Pulgar, Sofia; Quer, Josep; Ramirez, Santseharay et al.
DOI: 10.1099/jgv.0.000289

Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis.

PMID: 26691857
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Dec 21;10(12):e0145147. doi: 10.1371/journal.pone.0145147. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Affo, Silvia; Altamirano, Jose; Arroyo, Vicente; Bataller, Ramon; Blaya, Delia; Caballeria, Joan; Coll, Mar; Gines, Pere; Millan, Cristina; Morales-Ibanez, Oriol et al.
DOI: 10.1371/journal.pone.0145147

Seven-Year Efficacy and Safety of Treatment with Tenofovir Disoproxil Fumarate for Chronic Hepatitis B Virus Infection.

PMID: 25532501
Journal: DIGEST DIS SCI
Year: 2015
Reference: Dig Dis Sci. 2015 May;60(5):1457-64. doi: 10.1007/s10620-014-3486-7. Epub 2014 Dec 23.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar Schall, Raul; Buti, Maria; Charuworn, Prista; Flaherty, John F; Flisiak, Robert; Gane, Edward; Gurel, Selim; Kitrinos, Kathryn M; Krastev, Zahary; Mani Subramanian, G et al.
DOI: 10.1007/s10620-014-3486-7

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus.

PMID: 25122776
Journal: JOURNAL OF VIROLOGY
Year: 2014
Reference: J Virol. 2014 Oct;88(20):12098-111. doi: 10.1128/JVI.01860-14. Epub 2014 Aug 13.
Impact factor:
Publication type: Paper in international publication
Authors: Beach, Nathan M; Domingo, Esteban; Esteban, Juan Ignacio; Gallego, Isabel; Gregori, Josep; Martinez-Salas, Encarnacion; Moreno, Elena; Perales, Celia; Pineiro, David; Quer, Josep et al.
DOI: 10.1128/JVI.01860-14

Effects of ribavirin monotherapy on the viral population in patients with chronic hepatitis C genotype 1: direct sequencing and pyrosequencing of the HCV regions.

PMID: 25091333
Journal: JOURNAL OF MEDICAL VIROLOGY
Year: 2014
Reference: J Med Virol. 2014 Nov;86(11):1886-97. doi: 10.1002/jmv.24035. Epub 2014 Aug 5.
Impact factor:
Publication type: Paper in international publication
Authors: Maldonado, A Martin-Lagos; Martin-Alvarez, A; Munoz-de-Rueda, P; Quer, J; Quiles-Perez, R; Salmeron, J et al.
DOI: 10.1002/jmv.24035

Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial.

PMID: 24907224
Journal: LANCET
Year: 2014
Reference: Lancet. 2014 Aug 2;384(9941):414-26. doi: 10.1016/S0140-6736(14)60538-9. Epub 2014 Jun 4.
Impact factor:
Publication type: Clinical Trials
Authors: Beumont-Mauviel, Maria; Buti, Maria; de Araujo, Evaldo Stanislau Affonso; De La Rosa, Guy; Horsmans, Yves; Janczewska, Ewa; Kalmeijer, Ronald; Lenz, Oliver; Manns, Michael; Marcellin, Patrick et al.
DOI: 10.1016/S0140-6736(14)60538-9

Strategies to manage hepatitis C virus (HCV) disease burden.

PMID: 24713006
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2014
Reference: J Viral Hepat. 2014 May;21 Suppl 1:60-89. doi: 10.1111/jvh.12249.
Impact factor:
Publication type: Paper in international publication
Authors: Akarca, U; Aleman, S; Balik, I; Berg, T; Bihl, F; Bilodeau, M; Blasco, A J; Brandao Mello, C E; Bruggmann, P; Buti, M et al.
DOI: 10.1111/jvh.12249

[Meeting Report: 20 years after the First International Symposium on hepatitis C virus and related viruses.]

PMID: 24011709
Journal: Gastroenterologia y Hepatologia
Year: 2013
Reference: Gastroenterol Hepatol. 2013 Dec;36(10):641-6. doi: 10.1016/j.gastrohep.2013.06.001. Epub 2013 Sep 5.
Impact factor:
Publication type: Paper in national publication
Authors: Carnero, Elena; Diez, Juana; Fortes, Purificacion; Gastaminza, Pablo; Lopez-Labrador, F Xavier; Majano, Pedro; Martinez, Miguel Angel; Perez-Del-Pulgar, Sofia; Quer, Josep et al.
DOI: 10.1016/j.gastrohep.2013.06.001

The state of hepatitis B and C in the Mediterranean and Balkan countries: report from a summit conference.

PMID: 23827008
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2013
Reference: J Viral Hepat. 2013 Aug;20 Suppl 2:1-20. doi: 10.1111/jvh.12120.
Impact factor:
Publication type: Paper in international publication
Authors: Alcorn, K; Ben-Alaya Bouafif, N; Benazzouz, M; Berkane, S; Buti, M; Carballo, M; Cortes Martins, H; Deuffic-Burban, S; Dominguez, A; Donoghoe, M et al.
DOI: 10.1111/jvh.12120

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis.

PMID: 23976977
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Aug 16;8(8):e71039. doi: 10.1371/journal.pone.0071039.
Impact factor:
Publication type: Paper in international publication
Authors: Domingo, Esteban; Esteban, Juan I; Grande-Perez, Ana; Gregori, Josep; Ortega-Prieto, Ana M; Perales, Celia; Quer, Josep; Sheldon, Julie; Tejero, Hector et al.
DOI: 10.1371/journal.pone.0071039

Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy: A randomized double-blind study.

PMID: 23872605
Journal: JOURNAL OF HEPATOLOGY
Year: 2013
Reference: J Hepatol. 2013 Dec;59(6):1184-92. doi: 10.1016/j.jhep.2013.07.020. Epub 2013 Jul 19.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Cordoba, Juan; Esteban, Rafael; Ferrer, Roser; Fuentes, Inma; Garcia-Martinez, Rita; Gines, Pere; Gomez, Susana; Guevara, Monica; Nieto, Juan C et al.
DOI: 10.1016/j.jhep.2013.07.020

T cell responses and viral variability in blood donation candidates with occult hepatitis B infection.

PMID: 22173156
Journal: JOURNAL OF HEPATOLOGY
Year: 2012
Reference: J Hepatol. 2012 Apr;56(4):765-74. Epub 2011 Dec 13.
Impact factor:
Publication type: Paper in international publication
Authors: Bes, Marta; Casamitjana, Natalia; Esteban, Juan Ignacio; Guardia, Jaime; Pinacho, Asuncion; Piron, Maria; Puig, Lluis; Quer, Josep; Sauleda, Silvia; Vargas, Victor et al.
DOI: 10.1016/j.jhep.2011.11.011

Tenofovir disoproxil fumarate in the treatment of chronic hepatitis B.

PMID: 22928893
Journal: Expert Review of Hematology
Year: 2012
Reference: Expert Rev Gastroenterol Hepatol. 2012 Aug;6(4):413-21. doi: 10.1586/egh.12.19.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Homs, Maria et al.
DOI: 10.1586/egh.12.19

Predicted Effects of Treatment for HCV Infection Vary Among European Countries.

PMID: 22863764
Journal: GASTROENTEROLOGY
Year: 2012
Reference: Gastroenterology. 2012 Oct;143(4):974-85.e14. doi: 10.1053/j.gastro.2012.05.054. Epub 2012 Aug 2.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Deltenre, Pierre; Deuffic-Burban, Sylvie; Hatzakis, Angelos; Mathurin, Philippe; Moreno, Christophe; Muhlberger, Nikolai; Parkes, Julie; Rosenberg, William; Siebert, Uwe et al.
DOI: 10.1053/j.gastro.2012.05.054

[Consensus document of the spanish association for the study of the liver on the treatment of Hepatitis B infection (2012).]

PMID: 22749508
Journal: Gastroenterologia y Hepatologia
Year: 2012
Reference: Gastroenterol Hepatol. 2012 Aug-Sep;35(7):512-28. doi: 10.1016/j.gastrohep.2012.04.006. Epub 2012 Jun 29.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.gastrohep.2012.04.006

The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference*.

PMID: 21824223
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2011
Reference: J Viral Hepat. 2011 Sep;18 Suppl 1:1-16. doi: 10.1111/j.1365-2893.2011.01499.x.
Impact factor:
Publication type: Paper in international publication
Authors: Bruix, J; Buti, M; Carballo, M; Cavaleri, M; Colombo, M; Delarocque-Astagneau, E; Dusheiko, G; Esmat, G; Esteban, R; Goldberg, D et al.
DOI: 10.1111/j.1365-2893.2011.01499.x

Abacavir coadministration does not interfere with the suppressive activity of ribavirin in an HCV replicon system.

PMID: 21900721
Journal: ANTIVIRAL THERAPY
Year: 2011
Reference: Antivir Ther. 2011;16(6):887-93.
Impact factor:
Publication type: Paper in international publication
Authors: Crespo, Manuel; Cubero, Maria; Curran, Adria; Esteban, Juan I; Falco, Vicenc; Garcia-Cehic, Damir; Homs, Maria; Pahissa, Albert; Quer, Josep; Ribera, Esteban et al.
DOI: 10.3851/IMP1861

1990-2010: two decades of interferon-based therapy.

PMID: 21867931
Journal: Clinics in Liver Disease
Year: 2011
Reference: Clin Liver Dis. 2011 Aug;15(3):473-82. Epub 2011 Jun 14.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Esteban, Rafael et al.
DOI: 10.1016/j.cld.2011.05.007

[Hepatic elastography. Position paper of the Catalan Society of Gastroenterology.]

PMID: 21783282
Journal: Gastroenterologia y Hepatologia
Year: 2011
Reference: Gastroenterol Hepatol. 2011 Aug-Sep;34(7):504-10. Epub 2011 Jul 23.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.gastrohep.2011.05.008

Motor-evoked potentials in awake rats are a valid method of assessing hepatic encephalopathy and of studying its pathogenesis.

PMID: 20890898
Journal: HEPATOLOGY
Year: 2010
Reference: Hepatology. 2010 Dec;52(6):2077-85. doi: 10.1002/hep.23938. Epub 2010 Oct 1.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1002/hep.23938

[Recommendations for the management of Sorafenib in patients with hepatocellular carcinoma.]

PMID: 20851505
Journal: Gastroenterol Hepatol
Year: 2010
Reference: Gastroenterol Hepatol. 2010 Dec;33(10):741-52. Epub 2010 Sep 18.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.gastrohep.2010.05.007

High doses of beta-blockers and alcohol abstinence improve long-term rebleeding and mortality in cirrhotic patients after an acute variceal bleeding.

PMID: 20536715
Journal: LIVER INTERNATIONAL
Year: 2010
Reference: Liver Int. 2010 Sep;30(8):1123-30. Epub 2010 Jun 1.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1111/j.1478-3231.2010.02287.x

Laboratory testing of individuals with severe alpha1-antitrypsin deficiency in three European centres.

PMID: 20436173
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2010
Reference: Eur Respir J. 2010 May;35(5):960-8.
Impact factor:
Publication type: Paper in international publication
Authors: Bals, R; Ferrarotti, I; Herr, C; Jardi, R; Luisetti, M; Miravitlles, M; Rodriguez-Frias, F et al.
DOI: 10.1183/09031936.00069709

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.

PMID: 19208682
Journal: GENOME RESEARCH
Year: 2009
Reference: Genome Res. 2009 Mar;19(3):438-51.
Impact factor:
Publication type: Paper in international publication
Authors: Acquadro, Francesco; Allende, Helena; Ballestar, Esteban; Bosch, Francesc X; Buti, Maria; Cahir-McFarland, Ellen; Capella, Gabriel; Capello, Daniela; Carmona, Francisco J; Castellsague, Xavier et al.
DOI: 10.1101/gr.083550.108

Current trends in chronic hepatitis B management: results of a questionnaire.

PMID: 19430301
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2009
Reference: Eur J Gastroenterol Hepatol. 2009 Oct;21(10):1177-83.
Impact factor:
Publication type: Paper in international publication
Authors: ; Buti, Maria; Cordoba, Juan; Esteban, Rafael; Garcia-Martinez, Rita; Les, Inigo et al.
DOI: 10.1097/MEG.0b013e3283154f3a

Use of the novel INNO-LiPA line probe assay for detection of hepatitis B virus variants that confer resistance to entecavir therapy.

PMID: 19052182
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2009
Reference: J Clin Microbiol. 2009 Feb;47(2):485-8.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Esteban, Rafael; Homs, Maria; Jardi, Rosendo; Rodriguez-Frias, Francisco; Schaper, Melanie; Tabernero, David et al.
DOI: 10.1128/JCM.01678-08

[Diagnosis and treatment of hepatocellular carcinoma]

PMID: 19248879
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 Feb 28;132(7):272-87.
Impact factor:
Publication type: Paper in national publication
Authors: Ayuso, Carmen; Bru, Concepcio; Bruix, Jordi; Buti, Maria; de la Mata, Manuel; Forner, Alejandro; Isabel Real, Maria; Llovet, Josep M; Marti-Bonmati, Luis; Robles, Ricardo et al.
DOI: 10.1016/j.medcli.2008.11.024

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The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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