About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37771546 Journal: JHEP Reports Year: 2023 Reference: JHEP Rep. 2023 Jul 13;5(10):100847. doi: 10.1016/j.jhepr.2023.100847. eCollection 2023 Oct. Impact factor: Publication type: Paper in international publication Authors: Abramov, Frida; Agarwal, Kosh; Ahn, Sang Hoon; Brunetto, Maurizia; Buti, Maria; Buti, Maria; Chan, Henry L Y; Chang, Ting-Tsung; Chuang, Wan Long; Flaherty, John F et al. DOI: 10.1016/j.jhepr.2023.100847
PMID: 37801035 Journal: FASEB JOURNAL Year: 2023 Reference: FASEB J. 2023 Nov;37(11):e23220. doi: 10.1096/fj.202300077R. Impact factor: Publication type: Paper in international publication Authors: Albillos, Agustin; Alter, David N; Asselta, Rosanna; Banales, Jesus M; Brewer, Jo; Bujanda, Luis; Buti, Maria; Buti, Maria; Conway, Joseph; de Cid, Rafael et al. DOI: 10.1096/fj.202300077R
PMID: 37802221 Journal: Contemporary Clinical Trials Year: 2023 Reference: Contemp Clin Trials. 2023 Oct 4:107352. doi: 10.1016/j.cct.2023.107352. Impact factor: Publication type: Paper in international publication Authors: Agustin, Salvador; Agustin, Salvador; Aithal, Guruprasad P; Akhtar, Salma; Aller, Rocio; Allison, Michael; Anstee, Quentin M; Antonucci, Michela; Aube, Christophe; Banerjee, Rajarshi et al. DOI: 10.1016/j.cct.2023.107352
PMID: 37808908 Journal: Frontiers in Cellular and Infection Microbiology Year: 2023 Reference: Front Cell Infect Microbiol. 2023 Sep 21;13:1175996. doi: 10.3389/fcimb.2023.1175996. eCollection 2023. Impact factor: Publication type: Review in international publication Authors: Quer, Josep; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco et al. DOI: 10.3389/fcimb.2023.1175996
PMID: 34256936 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 May 27;158(10):466-471. doi: 10.1016/j.medcli.2021.05.013. Epub 2021 Jun 16. Impact factor: Publication type: Paper in national publication Authors: Arranz-Betegon, Maria; Canas-Ruano, Esperanza; Domingo-Baldrich, Eva; Fernandez-Codina, Andreu; Garcia-Vives, Eloi; Gil-Vila, Albert; Llaneras-Artigues, Jordi; Meza, Beatriz; Michelena, Xabier; Orozco-Galvez, Olimpia et al. DOI: 10.1016/j.medcli.2021.05.013
PMID: 34919762 Journal: LIVER TRANSPLANTATION Year: 2022 Reference: Liver Transpl. 2022 Jun;28(6):1039-1050. doi: 10.1002/lt.26389. Epub 2022 Jan 17. Impact factor: Publication type: Paper in international publication Authors: Alonso-Fernandez, Roberto; Arias-Milla, Ana; Banares, Rafael; Blanco-Fernandez, Gerardo; Bustamante, Francisco Javier; Caballero-Marcos, Aranzazu; Cachero, Alba; Calatayud, Laura; Castells, Lluis; Citores, Maria Jesus et al. DOI: 10.1002/lt.26389
PMID: 35569757 Journal: Journal of Global Antimicrobial Resistance Year: 2022 Reference: J Glob Antimicrob Resist. 2022 Jun;29:386-389. doi: 10.1016/j.jgar.2022.05.003. Epub 2022 May 13. Impact factor: Publication type: Paper in international publication Authors: Ambretti, Simone; Amedeo, Alberto; Bartoletti, Michele; Beci, Giacomo; Bussini, Linda; Carvalho-Brugger, Sulamita; Giannella, Maddalena; Giglia, Maddalena; Gutierrez, Laura; Pascale, Renato et al. DOI: 10.1016/j.jgar.2022.05.003
PMID: 35566592 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Apr 27;11(9). pii: jcm11092466. doi: 10.3390/jcm11092466. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Banares, Juan; Bermudez, Maria; Castells, Lluis; Manzano, Ramiro; Minguez, Beatriz; Pericas, Juan M; Pons, Monica; Rivera-Esteban, Jesus; Salcedo-Allende, Maria Teresa et al. DOI: 10.3390/jcm11092466
PMID: 33892004 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Sep;75(3):750-752. doi: 10.1016/j.jhep.2021.04.019. Epub 2021 Apr 20. Impact factor: Publication type: Letter or abstract Authors: Abraldes, Juan G; Bosch, Jaime; Genesca, Joan et al. DOI: 10.1016/j.jhep.2021.04.019
PMID: 33880971 Journal: EXPERT REVIEW OF MOLECULAR DIAGNOSTICS Year: 2021 Reference: Expert Rev Mol Diagn. 2021 Apr;21(4):381-396. doi: 10.1080/14737159.2021.1913055. Epub 2021 Apr 21. Impact factor: Publication type: Review in international publication Authors: Buti, Maria; Cortese, Maria Francesca; Garcia-Garcia, Selene; Quer, Josep; Rando-Segura, Ariadna; Rodriguez-Algarra, Francisco; Rodriguez-Frias, Francisco; Tabernero, David et al. DOI: 10.1080/14737159.2021.1913055
PMID: 33358780 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 May;74(5):1246-1248. doi: 10.1016/j.jhep.2020.12.018. Epub 2020 Dec 20. Impact factor: Publication type: Letter or abstract Authors: Buti, Maria; Casado, Miguel Angel; Dominguez-Hernandez, Raquel et al. DOI: 10.1016/j.jhep.2020.12.018
PMID: 33227350 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 May;74(5):1097-1108. doi: 10.1016/j.jhep.2020.11.019. Epub 2020 Nov 20. Impact factor: Publication type: Paper in international publication Authors: Acevedo, Juan; Aguilar, Ferran; Albillos, Agustin; Alessandria, Carlo; Amoros, Alex; Angeli, Paolo; Arroyo, Vicente; Balogh, Boglarka; Banares, Rafael; Berg, Thomas et al. DOI: 10.1016/j.jhep.2020.11.019
PMID: 31394283 Journal: Clinical Gastroenterology and Hepatology Year: 2020 Reference: Clin Gastroenterol Hepatol. 2020 Apr;18(4):963-973.e14. doi: 10.1016/j.cgh.2019.07.055. Epub 2019 Aug 5. Impact factor: Publication type: Paper in international publication Authors: Aagaard, N K; Albillos, A; Alessandria, C; Amoros, A; Angeli, P; Arroyo, V; Arteaga, M; Aziz, F; Banares, R; Campion, D et al. DOI: 10.1016/j.cgh.2019.07.055
PMID: 32192825 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Jun;72(6):1218-1220. doi: 10.1016/j.jhep.2020.03.002. Epub 2020 Mar 17. Impact factor: Publication type: Letter or abstract Authors: Aguilar, Ferran; Albillos, Agustin; Alessandria, Carlo; Angeli, Paolo; Arroyo, Vicente; Baldassarre, Maurizio; Banares, Rafael; Benten, Daniel; Bernal, William; Bernardi, Mauro et al. DOI: 10.1016/j.jhep.2020.03.002
PMID: 31778751 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Apr;72(4):688-701. doi: 10.1016/j.jhep.2019.11.009. Epub 2019 Nov 25. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Ferran; Albillos, Agustin; Alessandria, Carlo; Angeli, Paolo; Arroyo, Vicente; Baldasarre, Maurizio; Banares, Rafael; Benten, Daniel; Bernal, William; Bernardi, Mauro et al. DOI: 10.1016/j.jhep.2019.11.009
PMID: 32170821 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 Jun;40(6):1467-1476. doi: 10.1111/liv.14436. Epub 2020 Apr 15. Impact factor: Publication type: Paper in international publication Authors: Aballay Soteras, Gabriel; Alvares-da-Silva, Mario Reis; Alves, Rogerio; Anders, Margarita; Arenas, Juan Ignacio; Bruix, Jordi; Chagas, Aline Lopes; Coll, Susanna; Delgado, Manuel; Di Costanzo, Giovan Giuseppe et al. DOI: 10.1111/liv.14436
PMID: 31203153 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 Oct;71(4):666-672. doi: 10.1016/j.jhep.2019.06.002. Epub 2019 Jun 14. Impact factor: 18.946 Publication type: Paper in international publication Authors: Marino, Zoe, Torras, Xavier, Luis Calleja, Jose, Antonio Carrion, Jose, Fernandez, Inmaculada, Maria Morillas, Rosa, Miguel Rosales, Jose, Carmona, Isabel, Fernandez-Rodriguez, Conrado, Hernandez-Guerra, Manuel et al. DOI: 10.1016/j.jhep.2019.06.002
PMID: 31118701 Journal: Infection and Drug Resistance Year: 2019 Reference: Infect Drug Resist. 2019 Apr 24;12:947-955. doi: 10.2147/IDR.S195441. eCollection 2019. Impact factor: 3 Publication type: Paper in international publication Authors: von Massow, Georg, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Macia, Maria Dolores, Escarda, Ana, Esteban, Juan Ignacio, Quer, Josep et al. DOI: 10.2147/IDR.S195441
PMID: 30983817 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2019 Reference: World J Gastroenterol. 2019 Apr 7;25(13):1566-1579. doi: 10.3748/wjg.v25.i13.1566. Impact factor: 3.411 Publication type: Paper in international publication Authors: Godoy, Cristina, Tabernero, David, Sopena, Sara, Gregori, Josep, Cortese, Maria Francesca, Gonzalez, Carolina, Casillas, Rosario, Yll, Marcal, Rando, Ariadna, Lopez-Martinez, Rosa et al. DOI: 10.3748/wjg.v25.i13.1566
PMID: 30842623 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Mar 6;9(1):3678. doi: 10.1038/s41598-019-40099-3. Impact factor: 4.011 Publication type: Paper in international publication Authors: Saludes, V, Antuori, A, Reinhardt, B, Viciana, I, Clavijo, E, Schreiber, L, Tenenbaum, M, Rodriguez-Frias, F, Quer, J, Matas, L et al. DOI: 10.1038/s41598-019-40099-3
PMID: 28856972 Journal: Expert Review of Gastroenterology & Hepatology Year: 2018 Reference: Expert Rev Gastroenterol Hepatol. 2018 Feb;12(2):155-164. doi: 10.1080/17474124.2017.1374852. Epub 2017 Sep 12. Impact factor: Publication type: Paper in international publication Authors: Genesca, Joan; Roccarina, Davide; Rosselli, Matteo; Tsochatzis, Emmanuel A et al. DOI: 10.1080/17474124.2017.1374852
PMID: 28833714 Journal: TRANSPLANT INTERNATIONAL Year: 2018 Reference: Transpl Int. 2018 Jan;31(1):38-44. doi: 10.1111/tri.13037. Epub 2017 Sep 27. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Castells, Lluis; Charco, Ramon; Juamperez, Javier; Molino, Jose A; Ortega, Juan; Quintero, Jesus; Rodrigo, Carlos et al. DOI: 10.1111/tri.13037
PMID: 28710554 Journal: OBESITY SURGERY Year: 2018 Reference: Obes Surg. 2018 Jan;28(1):142-151. doi: 10.1007/s11695-017-2805-4. Impact factor: Publication type: Paper in international publication Authors: Arus-Aviles, Marc; Augustin, Salvador; Balibrea, Jose M; Beisani, Marc; Chakkur, Aisha; Cremades, Manel; Martell, Maria; Rodriguez-Navarro, Sarai; Salcedo-Allende, Maria Teresa; Talavera-Urquijo, Eider et al. DOI: 10.1007/s11695-017-2805-4
PMID: 28501536 Journal: Clinical Gastroenterology and Hepatology Year: 2018 Reference: Clin Gastroenterol Hepatol. 2018 Jan;16(1):132-139.e8. doi: 10.1016/j.cgh.2017.04.042. Epub 2017 May 10. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Amitrano, Lucio; Augustin, Salvador; Cachero, Alba; Castellote, Josep; Conejo, Irene; Genesca, Joan; Guardascione, Maria Anna; Tandon, Puneeta et al. DOI: 10.1016/j.cgh.2017.04.042
PMID: 28192235 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Oct;23(10):775.e1-775.e6. doi: 10.1016/j.cmi.2017.02.007. Epub 2017 Feb 10. Impact factor: Publication type: Paper in international publication Authors: Asensio, Miriam; Augustin, Salvador; Blasi, Maria; Buti, Maria; Carbonell, Judit; Casillas, Rosario; Castells, Lluis; Chen, Qian; Esteban, Juan Ignacio; Esteban, Rafael et al. DOI: 10.1016/j.cmi.2017.02.007
PMID: 28170112 Journal: HEPATOLOGY Year: 2017 Reference: Hepatology. 2017 Jun;65(6):1810-1822. doi: 10.1002/hep.29097. Epub 2017 Apr 28. Impact factor: Publication type: Paper in international publication Authors: Albillos, Agustin; Arenas, Juan; Badia, Ester; Baliellas, Carme; Ble, Michel; Buti, Maria; Calleja, Jose Luis; Carrion, Jose Antonio; Castells, Lluis; Crespo, Javier et al. DOI: 10.1002/hep.29097
PMID: 28159349 Journal: MEDICINA CLINICA Year: 2017 Reference: Med Clin (Barc). 2017 Mar 22;148(6):277-282. doi: 10.1016/j.medcli.2016.12.018. Epub 2017 Jan 31. Impact factor: Publication type: Paper in national publication Authors: Blasco, Antonio Javier; Buti, Maria; Calleja, Jose Luis; Crespo, Javier; Garcia-Samaniego, Javier; Lazaro, Pablo; Razavi, Homie; Robbins, Sarah; Romero, Manuel; Serra, Miguel Angel et al. DOI: 10.1016/j.medcli.2016.12.018
PMID: 28120471 Journal: HEPATOLOGY Year: 2017 Reference: Hepatology. 2017 Aug;66(2):555-563. doi: 10.1002/hep.29080. Epub 2017 Jun 22. Impact factor: Publication type: Paper in international publication Authors: Ait Oufella, Hafid; Altamirano, Jose; Bataller, Ramon; Bedossa, Pierre; Bissonnette, Julien; Boulanger, Chantal M; Caballeria, Joan; Devue, Cecile; Durand, Francois; Gines, Pere et al. DOI: 10.1002/hep.29080
PMID: 27877030 Journal: International Journal of Chronic Obstructive Pulmonary Disease Year: 2016 Reference: Int J Chron Obstruct Pulmon Dis. 2016 Oct 11;11:2535-2541. eCollection 2016. Impact factor: 3.046 Publication type: Paper in international publication Authors: Rodriguez-Frias, Francisco, Belmonte, Irene, Barrecheguren, Miriam, Lopez-Martinez, Rosa M, Esquinas, Cristina, Rodriguez, Esther, Miravitlles, Marc et al. DOI: 10.2147/COPD.S115940
PMID: 27388262 Journal: DIGESTIVE AND LIVER DISEASE Year: 2016 Reference: Dig Liver Dis. 2016 Oct;48(10):1214-9. doi: 10.1016/j.dld.2016.06.019. Epub 2016 Jun 25. Impact factor: 2.719 Publication type: Paper in international publication Authors: Pons, Monica, Simon-Talero, Macarena, Millan, Laura, Ventura-Cots, Meritxell, Santos, Begona, Augustin, Salvador, Genesca, Joan et al. DOI: 10.1016/j.dld.2016.06.019
PMID: 27362848 Journal: PLoS One Year: 2016 Reference: PLoS One. 2016 Jun 30;11(6):e0158557. doi: 10.1371/journal.pone.0158557. eCollection 2016. Impact factor: 3.057 Publication type: Paper in international publication Authors: Ruiz, Alicia, Homs, Maria, Rodriguez-Frias, Francisco, Gregori, Josep, Tabernero, David, Godoy, Cristina, Barakat, Salma, Quer, Josep, Riveiro-Barciela, Mar, Roggendorf, Michael et al. DOI: 10.1371/journal.pone.0158557
PMID: 27343299 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2016 Reference: J Clin Microbiol. 2016 Jul;54(7):1933. doi: 10.1128/JCM.01007-16. Impact factor: 3.631 Publication type: Paper in international publication Authors: Sauleda, Silvia, Bes, Marta, Gomez, Jordi, Briones, Carlos, Perales, Celia, Sheldon, Julie, Castells, Lluis, Viladomiu, Lluis, Salmeron, Javier, Ruiz-Extremera, Angela et al. DOI: 10.1128/JCM.01007-16
PMID: 26071338 Journal: JOURNAL OF CLINICAL VIROLOGY Year: 2015 Reference: J Clin Virol. 2015 Jul;68:61-8. doi: 10.1016/j.jcv.2015.05.002. Epub 2015 May 8. Impact factor: 3.016 Publication type: Paper in international publication Authors: Buti, Maria, Casillas, Rosario, Riveiro-Barciela, Mar, Homs, Maria, Tabernero, David, Salcedo, Maria Teresa, Rodriguez-Frias, Francisco, Esteban, Rafael et al. DOI: 10.1016/j.jcv.2015.05.002
PMID: 25027067 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2015 Reference: Arch Bronconeumol. 2015 Apr;51(4):185-92. doi: 10.1016/j.arbres.2014.05.008. Epub 2014 Jul 12. Impact factor: 1.823 Publication type: Paper in national publication Authors: Casas, Francisco, Blanco, Ignacio, Martinez, Maria Teresa, Bustamante, Ana, Miravitlles, Marc, Cadenas, Sergio, Hernandez, Jose M, Lazaro, Lourdes, Rodriguez, Esther, Rodriguez-Frias, Francisco et al. DOI: 10.1016/j.arbres.2014.05.008
PMID: 25378574 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2015 Reference: J Clin Microbiol. 2015 Jan;53(1):219-26. doi: 10.1128/JCM.02093-14. Epub 2014 Nov 5. Impact factor: 3.993 Publication type: Paper in international publication Authors: Quer, Josep, Gregori, Josep, Rodriguez-Frias, Francisco, Buti, Maria, Madejon, Antonio, Perez-Del-Pulgar, Sofia, Garcia-Cehic, Damir, Casillas, Rosario, Blasi, Maria, Homs, Maria et al. DOI: 10.1128/JCM.02093-14
PMID: 24637729 Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY Year: 2015 Reference: J Clin Gastroenterol. 2015 Feb;49(2):165-8. doi: 10.1097/MCG.0000000000000113. Impact factor: 3.498 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Minguez, Beatriz, Girones, Rosa, Rodriguez-Frias, Francisco, Quer, Josep, Buti, Maria et al. DOI: 10.1097/MCG.0000000000000113
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
