About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37183551 Journal: LIVER INTERNATIONAL Year: 2023 Reference: Liver Int. 2023 May 15. doi: 10.1111/liv.15606. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Albillos, Agustin; Alvarado, Edilmar; Amitrano, Lucio; Banares, Rafael; Bataller, Ramon; Bosch, Jaime; Bureau, Christophe; Calleja, Jose L; Canete, Nuria et al. DOI: 10.1111/liv.15606
PMID: 37069601 Journal: World Journal of Emergency Surgery Year: 2023 Reference: World J Emerg Surg. 2023 Apr 17;18(1):30. doi: 10.1186/s13017-023-00498-4. Impact factor: Publication type: Review in international publication Authors: Chica-Yanten, Julian; de'Angelis, Nicola; Garcia, Alberto F; Ibn-Abdelouahab, Abdelaziz; Jimenez-Masip, Alba; Manzano-Nunez, Ramiro; Moore, Ernest E; Sartelli, Massimo et al. DOI: 10.1186/s13017-023-00498-4
PMID: 37861218 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2023 Reference: N Engl J Med. 2023 Oct 20. doi: 10.1056/NEJMoa2307980. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan Gonzalez; Ahn, Myung-Ju; Akamatsu, Hiroaki; Albillos, Agustin; Amitrano, Lucio; Anderson, Erik S; Balcar, Lorenz; Blackhall, Fiona; Borghaei, Hossein; Bosch, Jaime et al. DOI: 10.1056/NEJMoa2307980
PMID: 37870985 Journal: Hepatology Communications Year: 2023 Reference: Hepatol Commun. 2023 Oct 18;7(11):e0273. doi: 10.1097/HC9.0000000000000273. eCollection 2023 Nov 1. Impact factor: Publication type: Paper in international publication Authors: Albillos, Agustin; Ampuero, Javier; Andrade, Raul J; Angeli, Paolo; Arroyo, Vicente; Ballester, Maria Pilar; Belli, Luca; Berenguer, Marina; Berg, Thomas; Bongiovanni, Deborah et al. DOI: 10.1097/HC9.0000000000000273
PMID: 35567756 Journal: LIVER INTERNATIONAL Year: 2022 Reference: Liver Int. 2022 Jul;42(7):1697. doi: 10.1111/liv.15291. Epub 2022 May 23. Impact factor: Publication type: Letter or abstract Authors: Bataller, Ramon; Jimenez, Cesar; Vargas, Victor; Ventura-Cots, Meritxell et al. DOI: 10.1111/liv.15291
PMID: 35555847 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2022 Reference: J Viral Hepat. 2022 Jul;29(7):579-583. doi: 10.1111/jvh.13686. Epub 2022 May 23. Impact factor: Publication type: Paper in international publication Authors: Barreira, Ana; Buti, Maria; Casado, Miguel Angel; Dominguez-Hernandez, Raquel; Esteban, Rafael; Martinez-Camprecios, Joan; Palom, Adriana; Rando-Segura, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco et al. DOI: 10.1111/jvh.13686
PMID: 35532834 Journal: CLINICAL DRUG INVESTIGATION Year: 2022 Reference: Clin Drug Investig. 2022 Jun;42(Suppl 1):1-2. doi: 10.1007/s40261-022-01148-4. Epub 2022 May 9. Impact factor: Publication type: Letter or abstract Authors: Lledo-Navarro, Jose Luis; Minguez, Beatriz et al. DOI: 10.1007/s40261-022-01148-4
PMID: 34229038 Journal: Clinical Gastroenterology and Hepatology Year: 2022 Reference: Clin Gastroenterol Hepatol. 2022 Jun;20(6):e1456-e1468. doi: 10.1016/j.cgh.2021.06.048. Epub 2021 Jul 3. Impact factor: Publication type: Paper in international publication Authors: Alqahtani, Saleh; Alswat, Khalid; Arrese, Marco; Bugianesi, Elisabetta; Burra, Patrizia; Buti, Maria; Castera, Laurent; Chan, Wah-Kheong; Diago, Moises; Duseja, Ajay K et al. DOI: 10.1016/j.cgh.2021.06.048
PMID: 32663522 Journal: Clinical Gastroenterology and Hepatology Year: 2021 Reference: Clin Gastroenterol Hepatol. 2021 May;19(5):1030-1037. doi: 10.1016/j.cgh.2020.07.006. Epub 2020 Jul 11. Impact factor: Publication type: Paper in international publication Authors: Buti, M; Esteban, R; Llaneras, J; Marcos-Fosch, C; Rando-Segura, A; Riveiro-Barciela, M; Roade, L; Rodriguez-Frias, F; Velazquez, F et al. DOI: 10.1016/j.cgh.2020.07.006
PMID: 33845059 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Aug;75(2):342-350. doi: 10.1016/j.jhep.2021.03.026. Epub 2021 Jun 12. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Albillos, Agustin; Alvarado, Edilmar; Amitrano, Lucio; Banares, Rafael; Bosch, Jaime; Bureau, Christophe; Calleja, Jose Luis; Canete, Nuria; Casas, Meritxell et al. DOI: 10.1016/j.jhep.2021.03.026
PMID: 33835707 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2021 Reference: Am J Transplant. 2021 Aug;21(8):2876-2884. doi: 10.1111/ajt.16599. Epub 2021 Apr 27. Impact factor: Publication type: Letter whit IF Authors: Alamo-Martinez, Jose Maria; Alonso-Fernandez, Roberto; Arias-Milla, Ana; Blanco-Fernandez, Gerardo; Bustamante, Francisco Javier; Caballero-Marcos, Aranzazu; Cachero, Alba; Calatayud, Laura; Castells, Lluis; Colmenero, Jordi et al. DOI: 10.1111/ajt.16599
PMID: 33309778 Journal: GASTROENTEROLOGY Year: 2021 Reference: Gastroenterology. 2021 Apr;160(5):1725-1740.e2. doi: 10.1053/j.gastro.2020.12.008. Epub 2020 Dec 10. Impact factor: Publication type: Paper in international publication Authors: Adrover, Anna; Affo, Silvia; Altamirano, Jose; Alvarado-Tapias, Edilmar; Argemi, Josepmaria; Bataller, Ramon; Caballeria, Juan; Cameron, Andrew; Cao, Sheng; Dubuquoy, Laurent et al. DOI: 10.1053/j.gastro.2020.12.008
PMID: 32173382 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Aug;73(2):315-327. doi: 10.1016/j.jhep.2020.03.008. Epub 2020 Mar 12. Impact factor: Publication type: Paper in international publication Authors: Bassaganyas, Laia; Cabellos, Laia; Castellano, Giancarlo; Esteban-Fabro, Roger; Fiel, Maria I; Fuster, Josep; Labgaa, Ismail; Leow, Wei Q; Llovet, Josep M; Miho, Maeda et al. DOI: 10.1016/j.jhep.2020.03.008
PMID: 32165244 Journal: INFECTION GENETICS AND EVOLUTION Year: 2020 Reference: Infect Genet Evol. 2020 Aug;82:104278. doi: 10.1016/j.meegid.2020.104278. Epub 2020 Mar 9. Impact factor: Publication type: Review in international publication Authors: Briones, Carlos; de Avila, Ana Isabel; Domingo, Esteban; Gallego, Isabel; Garcia-Crespo, Carlos; Gomez, Jordi; Gregori, Josep; Martinez-Gonzalez, Brenda; Perales, Celia; Quer, Josep et al. DOI: 10.1016/j.meegid.2020.104278
PMID: 32147361 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Jul;73(1):17-25. doi: 10.1016/j.jhep.2020.02.028. Epub 2020 Mar 6. Impact factor: Publication type: Paper in international publication Authors: Albillos, Agustin; Aller, Rocio; Ampuero, Javier; Andrade, Raul J; Aspichueta, Patricia; Augustin, Salvador; Banales, Jesus; Benlloch, Salvador; Caballeria, Joan; Calleja, Jose Luis et al. DOI: 10.1016/j.jhep.2020.02.028
PMID: 32145129 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 May;40(5):1121-1129. doi: 10.1111/liv.14429. Epub 2020 Mar 24. Impact factor: Publication type: Paper in international publication Authors: Hirschfield, Gideon; Invernizzi, Pietro; Liberman, Alexander; MacConell, Leigh; Malecha, Elizabeth Smoot; Pares, Albert; Shiffman, Mitchell; Vargas, Victor et al. DOI: 10.1111/liv.14429
PMID: 30815504 Journal: Open Forum Infectious Diseases Year: 2019 Reference: Open Forum Infect Dis. 2019 Jan 16;6(2):ofz036. doi: 10.1093/ofid/ofz036. eCollection 2019 Feb. Impact factor: 3.371 Publication type: Paper in international publication Authors: Gimeno, A, Benito, R, Algarate, S, Gil, J, Ortiz de Lejarazu, R, Rojo, S, Eiros, J M, San Miguel, A, Manzardo, C, Miro, J M et al. DOI: 10.1093/ofid/ofz036
PMID: 30768983 Journal: GASTROENTEROLOGY Year: 2019 Reference: Gastroenterology. 2019 May;156(6):1820-1833. doi: 10.1053/j.gastro.2019.02.003. Epub 2019 Feb 12. Impact factor: 19.233 Publication type: Paper in international publication Authors: Hoffmann, Daniel, Wedemeyer, Heiner, Cornberg, Markus, Krawczyk, Adalbert, Rashidi-Alavijeh, Jassin, Rodriguez-Frias, Francisco, Casillas, Rosario, Buti, Maria, Smedile, Antonina, Alavian, Seyed Moayed et al. DOI: 10.1053/j.gastro.2019.02.003
PMID: 30684506 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 May;70(5):874-884. doi: 10.1016/j.jhep.2019.01.005. Epub 2019 Jan 24. Impact factor: 18.946 Publication type: Paper in international publication Authors: Ayuso, Carmen, Rios, Jose, Forns, Xavier, Bruix, Jordi, Reig, Maria, Sole, Manel, Vilana, Ramon, Inarrairaegui, Mercedes, Marino, Zoe, Darnell, Anna et al. DOI: 10.1016/j.jhep.2019.01.005
PMID: 29239718 Journal: JOURNAL OF GENERAL VIROLOGY Year: 2018 Reference: J Gen Virol. 2018 Jan;99(1):97-102. doi: 10.1099/jgv.0.000996. Epub 2017 Dec 14. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Chen, Qian; Esteban, Juan Ignacio; Esteban, Rafael; Garcia-Cehic, Damir; Gregori, Josep; Llorens, Meritxell; Nieto-Aponte, Leonardo; Ordeig, Laura; Perales, Celia et al. DOI: 10.1099/jgv.0.000996
PMID: 28988126 Journal: VIRUS RESEARCH Year: 2018 Reference: Virus Res. 2018 Jan 2;243:52-59. doi: 10.1016/j.virusres.2017.10.003. Epub 2017 Oct 4. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Esteban, Rafael; Godoy, Cristina; Gregori, Josep; Homs, Maria; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz, Alicia; Sopena, Sara; Tabernero, David et al. DOI: 10.1016/j.virusres.2017.10.003
PMID: 30259574 Journal: TRANSPLANT INTERNATIONAL Year: 2018 Reference: Transpl Int. 2018 Dec;31(12):1293-1317. doi: 10.1111/tri.13358. Impact factor: Publication type: Paper in international publication Authors: Adam, Rene; Andujar, Rafael Lopez; Azoulay, Daniel; Bachellier, Philippe; Bennet, William; Berlakovich, Gabriela; Boudjema, Karim; Cailliez, Valerie; Cherqui, Daniel; Colledan, Michele et al. DOI: 10.1111/tri.13358
PMID: 29232161 Journal: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY Year: 2018 Reference: Am J Respir Cell Mol Biol. 2018 Jun;58(6):706-716. doi: 10.1165/rcmb.2017-0179OC. Impact factor: 4.1 Publication type: Paper in international publication Authors: Belmonte, Irene, Rodriguez-Frias, Francisco, Vilar, Marcal, Saez, Raquel, Iturbe, Igor, Castillo, Silvia, Molina-Molina, Maria, Texido, Anna, Tirado-Conde, Gema, Lopez-Campos, Jose Luis et al. DOI: 10.1165/rcmb.2017-0179OC
PMID: 28084470 Journal: Scientific Reports Year: 2017 Reference: Sci Rep. 2017 Jan 13;7:40461. doi: 10.1038/srep40461. Impact factor: Publication type: Paper in international publication Authors: Garcia-Lezana, Teresa; Genesca, Joan; Martell, Maria; Raurell, Imma; Rodriguez, Sarai; Torres-Arauz, Manuel et al. DOI: 10.1038/srep40461
PMID: 28078526 Journal: DIGESTIVE DISEASES AND SCIENCES Year: 2017 Reference: Dig Dis Sci. 2017 Mar;62(3):784-793. doi: 10.1007/s10620-017-4448-7. Epub 2017 Jan 11. Impact factor: Publication type: Paper in international publication Authors: Acero, Doroteo; Aguirre, Alberto; Buti, Maria; Calleja, Jose L; Comas, Carmen; Crespo, Javier; de Cuenca, Beatriz; Esteban, Rafael; Fernandez-Bermejo, Miguel; Garcia-Samaniego, Javier et al. DOI: 10.1007/s10620-017-4448-7
PMID: 28061762 Journal: BMC INFECTIOUS DISEASES Year: 2017 Reference: BMC Infect Dis. 2017 Jan 7;17(1):45. doi: 10.1186/s12879-016-2106-x. Impact factor: Publication type: Paper in international publication Authors: Bucher, Heiner C; Calleja, Jose Luis; Castells, Lluis; Evans, David; Giostra, Emiliano; Hofer, Harald; Irving, William; Lefevre, Cinira; Pascasio, Juan Manuel; Postema, Roelien et al. DOI: 10.1186/s12879-016-2106-x
PMID: 28051797 Journal: Annals of Hepatology Year: 2017 Reference: Ann Hepatol. 2017 Jan-Feb 2017;16(1):86-93. doi: 10.5604/16652681.1226819. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Campos-Varela, Isabel; Castells, Lluis; Charco, Ramon; Crespo, Manel; Esteban, Juan Ignacio; Esteban-Mur, Rafael; Len, Oscar; Llaneras, Jordi; Rodriguez-Frias, Francisco et al. DOI: 10.5604/16652681.1226819
PMID: 26154193 Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE Year: 2016 Reference: Clin Chem Lab Med. 2016 Feb;54(2):241-8. doi: 10.1515/cclm-2015-0297. Impact factor: 3.017 Publication type: Paper in international publication Authors: Belmonte, Irene, Montoto, Luciana, Miravitlles, Marc, Barrecheguren, Miriam, Esquinas, Cristina, Rodriguez, Esther, Giralt, Marina, Rodriguez-Frias, Francisco et al. DOI: 10.1515/cclm-2015-0297
PMID: 27060566 Journal: VIROLOGY Year: 2016 Reference: Virology. 2016 Jun;493:227-37. doi: 10.1016/j.virol.2016.03.017. Epub 2016 Apr 6. Impact factor: 3.2 Publication type: Paper in international publication Authors: Domingo, Esteban, Quer, Josep, Gregori, Josep, Perales, Celia, Rodriguez-Frias, Francisco, Esteban, Juan I et al. DOI: 10.1016/j.virol.2016.03.017
PMID: 27037760 Journal: Transplant Infectious Disease Year: 2016 Reference: Transpl Infect Dis. 2016 Jun;18(3):442-445. doi: 10.1111/tid.12538. Epub 2016 Jun 9. Impact factor: 1.459 Publication type: Paper in international publication Authors: Crespo, M, Puig, T, Esteban, J I, Esteban, R, Santos, B, Castells, L, Llaneras, J et al. DOI: 10.1111/tid.12538
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
