About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 38139015 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Dec 6;24(24):17184. doi: 10.3390/ijms242417184. Impact factor: Publication type: Paper in international publication Authors: Abid, Islem; Bosch, Albert; Carcereny, Albert; Cereto-Massague, Adria; Costafreda, Maria Isabel; Garcia-Cehic, Damir; Garcia-Pedemonte, David; Gregori, Josep; Guerrero, Laura; Guix, Susana et al. DOI: 10.3390/ijms242417184
PMID: 38147137 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2023 Reference: J Am Soc Nephrol. 2023 Dec 26. doi: 10.1681/ASN.0000000000000287. Impact factor: Publication type: Paper in international publication Authors: Abbadessa, Giovanni; Adombi, Caroline Melanie; Ali, Nicole; Bestard, Oriol; Brar, Amarpali; Buti, Maria; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Cruzado, Josep M et al. DOI: 10.1681/ASN.0000000000000287
PMID: 38144422 Journal: Therapeutic Advances in Gastroenterology Year: 2023 Reference: Therap Adv Gastroenterol. 2023 Dec 22;16:17562848231218615. doi: 10.1177/17562848231218615. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Abid, Islem; Avellaneda, Nicolas; Bellato, Vittoria; Bettenworth, Dominik; Bosch, Albert; Brookes, Matthew J; Carcereny, Albert; Catalan-Serra, Ignacio; Cereto-Massague, Adria; Costafreda, Maria Isabel et al. DOI: 10.1177/17562848231218615
PMID: 34863359 Journal: LANCET Year: 2022 Reference: Lancet. 2022 Jan 1;399(10319):61-116. doi: 10.1016/S0140-6736(21)01701-3. Epub 2021 Dec 2. Impact factor: Publication type: Review in international publication Authors: Barrett, Damon; Belloni, Annalisa; Bugianesi, Elisabetta; Burra, Patrizia; Burton, Robyn; Buti, Maria; Byrne, Chris D; Carrieri, Patrizia; Cecchini, Michele; Cortez-Pinto, Helena et al. DOI: 10.1016/S0140-6736(21)01701-3
PMID: 34707258 Journal: Nature Reviews Gastroenterology & Hepatology Year: 2022 Reference: Nat Rev Gastroenterol Hepatol. 2022 Jan;19(1):60-78. doi: 10.1038/s41575-021-00523-4. Epub 2021 Oct 27. Impact factor: Publication type: Review in international publication Authors: Aberg, Fredrik; Adams, Leon; Allen, Alina M; Alnaser, Faisal; Alqahtani, Saleh A; Alswat, Khalid; Alvares-da-Silva, Mario Reis; Alvaro, Domenico; Andrade, Raul J; Anstee, Quentin M et al. DOI: 10.1038/s41575-021-00523-4
PMID: 35192963 Journal: Annals of Hepatology Year: 2022 Reference: Ann Hepatol. 2022 May-Jun;27(3):100687. doi: 10.1016/j.aohep.2022.100687. Epub 2022 Feb 19. Impact factor: Publication type: Paper in international publication Authors: Campos-Varela, Isabel; Castells, Lluis; Charco, Ramon; Diez, Iratxe; Patricia, Alvarez-Lopez; Quiroga, Sergi; Simon-Talero, Macarena et al. DOI: 10.1016/j.aohep.2022.100687
PMID: 35192964 Journal: Annals of Hepatology Year: 2022 Reference: Ann Hepatol. 2022 May-Jun;27(3):100685. doi: 10.1016/j.aohep.2022.100685. Epub 2022 Feb 19. Impact factor: Publication type: Paper in international publication Authors: Ayoub, Walid S; Buti, Maria; Gao, Xu; Geng, Yu; Huang, Rui; Ji, Fanpu; Li, Qingyu; Noureddin, Mazen; Su, Xingyang; Sundaram, Vinay et al. DOI: 10.1016/j.aohep.2022.100685
PMID: 33383399 Journal: EUROPEAN JOURNAL OF RADIOLOGY Year: 2021 Reference: Eur J Radiol. 2021 Feb;135:109484. doi: 10.1016/j.ejrad.2020.109484. Epub 2020 Dec 17. Impact factor: Publication type: Paper in international publication Authors: Ayuso, Carmen; Bruix, Jordi; Calleja, Jose Luis; Da Fonseca, Leonardo G; De La Torre-Alaez, Manuel; Guerrero, Antonio; Lledo, Jose Luis; Marquez, Laura; Matilla, Ana; Minguez, Beatriz et al. DOI: 10.1016/j.ejrad.2020.109484
PMID: 32781201 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Feb;74(2):330-339. doi: 10.1016/j.jhep.2020.07.046. Epub 2020 Aug 8. Impact factor: Publication type: Paper in international publication Authors: Alessandria, Carlo; Angeli, Paolo; Bartoletti, Michele; Bruns, Tony; Colombato, Luis; de Cassia Ribeiro Barea, Rita; Durand, Francois; Elkrief, Laure; Fernandez, Javier; Gadano, Adrian et al. DOI: 10.1016/j.jhep.2020.07.046
PMID: 33317846 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Feb;74(2):491. doi: 10.1016/j.jhep.2020.11.020. Epub 2020 Dec 11. Impact factor: Publication type: Letter or abstract Authors: Ayuso, Carmen; Belmonte, Ernest; Bruix, Jordi; Calleja, Jose Luis; Carrion, Jose Antonio; Coll, Susana; Darnell, Anna; Diaz, Alba; Forns, Xavier; Gallego, Adolfo et al. DOI: 10.1016/j.jhep.2020.11.020
PMID: 33461840 Journal: MEDICINA CLINICA Year: 2021 Reference: Med Clin (Barc). 2021 May 7;156(9):463.e1-463.e30. doi: 10.1016/j.medcli.2020.09.022. Epub 2021 Jan 16. Impact factor: Publication type: Paper in national publication Authors: Avila, Matias A; Ayuso, Carmen; Bilbao, Itxarone; Bilbao, Jose Ignacio; Bruix, Jordi; Burrel, Marta; Bustamante, Javier; De la Mata, Manuel; Ferrer, Joana; Forner, Alejandro et al. DOI: 10.1016/j.medcli.2020.09.022
PMID: 31607677 Journal: Lancet Gastroenterology & Hepatology Year: 2020 Reference: Lancet Gastroenterol Hepatol. 2020 Jan;5(1):31-41. doi: 10.1016/S2468-1253(19)30320-6. Epub 2019 Oct 10. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Alessandria, Carlo; Amin, Ahmed; Andrade, Raul J; Angeli, Paolo; Bernardi, Mauro; Beuers, Ulrich; Campion, Daniela; Caraceni, Paolo; Carol, Marta et al. DOI: 10.1016/S2468-1253(19)30320-6
PMID: 33521301 Journal: Year: 2020 Reference: Med Clin (Engl Ed). 2020 Dec 11;155(11):502-505. doi: 10.1016/j.medcle.2020.05.028. Epub 2020 Dec 14. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Cucchiari, David; Gumucio, Roberto; Md, Emmanuel Coloma; Nicolas, David; Pericas, Juan M; Riera, Josep et al. DOI: 10.1016/j.medcle.2020.05.028
PMID: 33116457 Journal: International Journal of Chronic Obstructive Pulmonary Disease Year: 2020 Reference: Int J Chron Obstruct Pulmon Dis. 2020 Oct 7;15:2421-2431. doi: 10.2147/COPD.S269641. eCollection 2020. Impact factor: 2.772 Publication type: Paper in international publication Authors: Belmonte, Irene, Nunez, Alexa, Barrecheguren, Miriam, Esquinas, Cristina, Pons, Monica, Lopez-Martinez, Rosa M, Ruiz, Gerard, Blanco-Grau, Albert, Genesca, Joan, Ferrer, Roser et al. DOI: 10.2147/COPD.S269641
PMID: 33076429 Journal: Cancers Year: 2020 Reference: Cancers (Basel). 2020 Oct 15;12(10). pii: cancers12102986. doi: 10.3390/cancers12102986. Impact factor: 6.126 Publication type: Paper in international publication Authors: Garcia-Gonzalez, Raul, Morejon-Garcia, Patricia, Campillo-Marcos, Ignacio, Salzano, Marcella, Lazo, Pedro A et al. DOI: 10.3390/cancers12102986
PMID: 28248445 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2017 Reference: J Viral Hepat. 2017 Sep;24(9):725-732. doi: 10.1111/jvh.12700. Epub 2017 Apr 10. Impact factor: 4.122 Publication type: Paper in international publication Authors: Navarro, Daniel, Rodriguez Frias, Francisco, Viciana, Isabel, Martinez-Sapina, Ana Maria, Rodriguez, Mario Jose, Martro, Elisa, Del Carmen Lozano, Maria, Coletta, Eleda, Cardenoso, Laura, Suarez, Avelina et al. DOI: 10.1111/jvh.12700
PMID: 27905173 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2017 Reference: J Viral Hepat. 2017 Jan;24(1):4-12. doi: 10.1111/jvh.12620. Epub 2016 Dec 1. Impact factor: 4.122 Publication type: Review in international publication Authors: Esteban, R, Buti, M, Llaneras, J, Riveiro-Barciela, M et al. DOI: 10.1111/jvh.12620
PMID: 28192235 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Oct;23(10):775.e1-775.e6. doi: 10.1016/j.cmi.2017.02.007. Epub 2017 Feb 10. Impact factor: 5.292 Publication type: Paper in international publication Authors: Ordeig, Laura, Rodriguez-Frias, Francisco, Nieto, Leonardo, Gregori, Josep, Garcia-Cehic, Damir, Casillas, Rosario, Tabernero, David, Homs, Maria, Blasi, Maria, Vila, Marta et al. DOI: 10.1016/j.cmi.2017.02.007
PMID: 28107169 Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE Year: 2017 Reference: Clin Chem Lab Med. 2017 Aug 28;55(9):1276-1283. doi: 10.1515/cclm-2016-0842. Impact factor: 3.432 Publication type: Paper in international publication Authors: Belmonte, Irene, Barrecheguren, Miriam, Esquinas, Cristina, Rodriguez, Esther, Miravitlles, Marc, Rodriguez-Frias, Francisco et al. DOI: 10.1515/cclm-2016-0842
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.