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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

Point-of-care hepatitis C testing and treatment strategy for people attending harm reduction and addiction centres for hepatitis C elimination.

PMID: 34806812
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2022
Reference: J Viral Hepat. 2022 Mar;29(3):227-230. doi: 10.1111/jvh.13634. Epub 2021 Nov 29.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Casado, Miguel Angel; Colom, Joan; Dominguez-Hernandez, Raquel; Forns, Xavier; Garcia-Retortillo, Montse; Lens, Sabela; Martro, Elisa; Quer, Joan Carles et al.
DOI: 10.1111/jvh.13634

Severe Infections Due to Respiratory Viruses.

PMID: 35172359
Journal: SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2022
Reference: Semin Respir Crit Care Med. 2022 Feb;43(1):60-74. doi: 10.1055/s-0041-1740982. Epub 2022 Feb 16.
Impact factor:
Publication type: Review in international publication
Authors: Cilloniz, Catia; Pericas, Juan M; Rojas, Jorge R; Torres, Antoni et al.
DOI: 10.1055/s-0041-1740982

Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study).

PMID: 35171022
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Feb 23;10(1):e0178421. doi: 10.1128/spectrum.01784-21. Epub 2022 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Berastegui, Cristina; Bravo, Carles; Campany-Herrero, David; Castells, Lluis; Deu, Maria; Gavalda, Joan; Len, Oscar; Los-Arcos, Ibai; Marquez-Algaba, Ester; Martin-Gomez, Maria Teresa et al.
DOI: 10.1128/spectrum.01784-21

The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study.

PMID: 34962498
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2022
Reference: Am J Gastroenterol. 2022 Feb 1;117(2):301-310. doi: 10.14309/ajg.0000000000001596.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, J G; Allison, M; Altamirano, J; Alvarado-Tapias, E; Arab, J P; Argemi, J; Atkinson, S R; Bataller, R; Brown, R S Jr; Charles, E A et al.
DOI: 10.14309/ajg.0000000000001596

Frailty in outpatients with cirrhosis: a prospective observational study.

PMID: 33030788
Journal: LIVER INTERNATIONAL
Year: 2021
Reference: Liver Int. 2021 Feb;41(2):357-368. doi: 10.1111/liv.14694. Epub 2020 Oct 29.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarado-Tapias, Edilmar; Ferrero-Gregori, Andreu; Flavia, Montserrat; Gallego, Adolfo; Gely, Cristina; Guarner, Carlos; Hernandez, Elvira; Nieto, Juan Camilo; Parramon, Marc; Poca, Maria et al.
DOI: 10.1111/liv.14694

The use of Rifaximin in Patients with Cirrhosis.

PMID: 33421158
Journal: HEPATOLOGY
Year: 2021
Reference: Hepatology. 2021 Sep;74(3):1660-1673. doi: 10.1002/hep.31708. Epub 2021 Jun 7.
Impact factor:
Publication type: Review in international publication
Authors: Alessandria, Carlo; Angeli, Paolo; Bajaj, Jasmohan S; Beuers, Ulrich; Caraceni, Paolo; de Wit, Koos; Durand, Francois; Gines, Pere; Krag, Aleksander; Mookerjee, Rajeshwar P et al.
DOI: 10.1002/hep.31708

Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalis Endocarditis in the GAMES Cohort (2008-2017).

PMID: 33413809
Journal: MAYO CLINIC PROCEEDINGS
Year: 2021
Reference: Mayo Clin Proc. 2021 Jan;96(1):132-146. doi: 10.1016/j.mayocp.2020.06.056.
Impact factor:
Publication type: Paper in international publication
Authors: Abad, Nuria Fernandez; Acebal, Juan Galvez; Adan, Ivan; Adell, Marta Matamala; Alamo, Elena Pisos; Alcolea, Eva Cascales; Almazan, Amaya Jimeno; Almela, Manuel; Alonso, Angel; Alonso, Luis Javier et al.
DOI: 10.1016/j.mayocp.2020.06.056

The case for simplifying and using absolute targets for viral hepatitis elimination goals.

PMID: 32979881
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2021
Reference: J Viral Hepat. 2021 Jan;28(1):12-19. doi: 10.1111/jvh.13412. Epub 2020 Nov 4.
Impact factor:
Publication type: Paper in international publication
Authors: Abaalkhail, Faisal; Abbas, Zaigham; Abdallah, Ayat; Abrao Ferreira, Paulo; Abu Raddad, Laith Jamal; Adda, Danjuma; Agarwal, Kosh; Aghemo, Alessio; Ahmed, Aijaz; Al-Busafi, Said A et al.
DOI: 10.1111/jvh.13412

Amino acid substitutions associated with treatment failure of hepatitis C virus infection.

PMID: 32999010
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2020
Reference: J Clin Microbiol. 2020 Nov 18;58(12). pii: JCM.01985-20. doi: 10.1128/JCM.01985-20. Print 2020 Nov 18.
Impact factor: 5.897
Publication type: Paper in international publication
Authors: Soria, Maria Eugenia, Garcia-Crespo, Carlos, Martinez-Gonzalez, Brenda, Vazquez-Sirvent, Lucia, Lobo-Vega, Rebeca, de Avila, Ana Isabel, Gallego, Isabel, Chen, Qian, Garcia-Cehic, Damir, Llorens-Revull, Meritxell et al.
DOI: 10.1128/JCM.01985-20

Toxicities from immunotherapy: From clinical trials to real-world clinical practice.

PMID: 32868034
Journal: MEDICINA CLINICA
Year: 2020
Reference: Med Clin (Barc). 2020 Dec 24;155(12):541-547. doi: 10.1016/j.medcli.2020.06.057. Epub 2020 Aug 28.
Impact factor: 1.635
Publication type: Review in national publication
Authors: Trallero-Araguas, Ernesto, Martinez-Valle, Fernando, Roca-Herrera, Maria, Zamora, Ester, Barreira-Diaz, Ana, Munoz-Couselo, Eva, Riveiro-Barciela, Mar et al.
DOI: 10.1016/j.medcli.2020.06.057

Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure.

PMID: 31857134
Journal: ANTIVIRAL RESEARCH
Year: 2020
Reference: Antiviral Res. 2020 Feb;174:104694. doi: 10.1016/j.antiviral.2019.104694. Epub 2019 Dec 16.
Impact factor: 4.101
Publication type: Paper in international publication
Authors: Niubo, Jordi, Chen, Qian, Perales, Celia, Soria, Maria Eugenia, Garcia-Cehic, Damir, Gregori, Josep, Rodriguez-Frias, Francisco, Buti, Maria, Crespo, Javier, Calleja, Jose Luis et al.
DOI: 10.1016/j.antiviral.2019.104694

Steatosis as main determinant of portal hypertension through a restriction of hepatic sinusoidal area in a dietary rat nash model.

PMID: 32770818
Journal: LIVER INTERNATIONAL
Year: 2020
Reference: Liver Int. 2020 Nov;40(11):2732-2743. doi: 10.1111/liv.14632. Epub 2020 Oct 13.
Impact factor: 5.175
Publication type: Paper in international publication
Authors: Barbera, Aurora, Raurell, Imma, Garcia-Lezana, Teresa, Torres-Arauz, Manuel, Bravo, Miren, Hide, Diana, Gil, Mar, Salcedo, Maria Teresa, Genesca, Joan, Martell, Maria et al.
DOI: 10.1111/liv.14632

Effectiveness and Safety of Entecavir or Tenofovir in a Spanish Cohort of Chronic Hepatitis B Patients: Validation of the Page-B Score to Predict Hepatocellular Carcinoma.

PMID: 28078526
Journal: DIGESTIVE DISEASES AND SCIENCES
Year: 2017
Reference: Dig Dis Sci. 2017 Mar;62(3):784-793. doi: 10.1007/s10620-017-4448-7. Epub 2017 Jan 11.
Impact factor: 2.875
Publication type: Paper in international publication
Authors: Moreno-Palomares, J J, Esteban, Rafael, Buti, Maria, de Cuenca, Beatriz, Sanchez-Pobre, Pilar, Moreno, Diego, Fernandez-Bermejo, Miguel, Riveiro-Barciela, Mar, Tabernero, David, Calleja, Jose L et al.
DOI: 10.1007/s10620-017-4448-7

Sofosbuvir and daclatasvir in mono- and HIV-coinfected patients with recurrent hepatitis C after liver transplant.

PMID: 28051797
Journal: Annals of Hepatology
Year: 2017
Reference: Ann Hepatol. 2017 Jan-Feb 2017;16(1):86-93. doi: 10.5604/16652681.1226819.
Impact factor: 1.678
Publication type: Paper in international publication
Authors: Salcedo, Teresa, Esteban, Juan Ignacio, Esteban-Mur, Rafael, Charco, Ramon, Rodriguez-Frias, Francisco, Len, Oscar, Crespo, Manel, Castells, Lluis, Llaneras, Jordi, Campos-Varela, Isabel et al.
DOI: 10.5604/16652681.1226819

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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