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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Publications

Influence of Type 2 Diabetes in the Association of PNPLA3 rs738409 and TM6SF2 rs58542926 Polymorphisms in NASH Advanced Liver Fibrosis.

PMID: 35625751
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 Apr 28;10(5). pii: biomedicines10051015. doi: 10.3390/biomedicines10051015.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Gabriel-Medina, Pablo, Ferrer-Costa, Roser, Rodriguez-Frias, Francisco, Ciudin, Andreea, Augustin, Salvador, Rivera-Esteban, Jesus, Pericas, Juan M, Selva, David Martinez et al.
DOI: 10.3390/biomedicines10051015

Hepatitis B Virus Variants with Multiple Insertions and/or Deletions in the X Open Reading Frame 3' End: Common Members of Viral Quasispecies in Chronic Hepatitis B Patients.

PMID: 35625929
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 May 21;10(5). pii: biomedicines10051194. doi: 10.3390/biomedicines10051194.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Rodriguez-Frias, Francisco, Garcia-Garcia, Selene, Caballero-Garralda, Andrea, Tabernero, David, Cortese, Maria Francesca, Gregori, Josep, Rodriguez-Algarra, Francisco, Quer, Josep, Riveiro-Barciela, Mar, Homs, Maria et al.
DOI: 10.3390/biomedicines10051194

A Nine-Strain Bacterial Consortium Improves Portal Hypertension and Insulin Signaling and Delays NAFLD Progression In Vivo.

PMID: 35625927
Journal: Biomedicines
Year: 2022
Reference: Biomedicines. 2022 May 20;10(5). pii: biomedicines10051191. doi: 10.3390/biomedicines10051191.
Impact factor: 6.081
Publication type: Paper in international publication
Authors: Augustin, Salvador, Martell, Maria, Salcedo, Maria Teresa, Pinheiro, Iris, Barbera, Aurora, Raurell, Imma, Estrella, Federico, de Leeuw, Marcel, Bolca, Selin, Gottardi, Davide et al.
DOI: 10.3390/biomedicines10051191

Indirect determination of biochemistry reference intervals using outpatient data.

PMID: 35588100
Journal: PLoS One
Year: 2022
Reference: PLoS One. 2022 May 19;17(5):e0268522. doi: 10.1371/journal.pone.0268522. eCollection 2022.
Impact factor: 3.24
Publication type: Paper in international publication
Authors: den Elzen, Wendy P J, Rodriguez-Frias, Francisco, Casis, Ernesto, Thelen, Marc, Martinez-Sanchez, Luisa, Cobbaert, Christa M, Noordam, Raymond, Brouwer, Nannette, Blanco-Grau, Albert, Villena-Ortiz, Yolanda et al.
DOI: 10.1371/journal.pone.0268522

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News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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