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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Team

Lluís Viladomiu Catà

Lluís Viladomiu Catà

Liver Diseases
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Macarena Simon-Talero Horga

Macarena Simon-Talero Horga

Main researcher
Liver Diseases
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María Bermúdez Ramos

María Bermúdez Ramos

Senior researcher
Liver Diseases
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Maria Buti Ferret

Maria Buti Ferret

Main researcher
Liver Diseases
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Maria del Mar Riveiro Barciela

Maria del Mar Riveiro Barciela

Main researcher
Liver Diseases
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Meritxell Ventura Cots

Meritxell Ventura Cots

Main researcher
Liver Diseases
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Lluís Viladomiu Catà

Lluís Viladomiu Catà

Liver Diseases
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Macarena Simon-Talero Horga

Macarena Simon-Talero Horga

Main researcher
Liver Diseases
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María Bermúdez Ramos

María Bermúdez Ramos

Senior researcher
Liver Diseases
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Maria Buti Ferret

Maria Buti Ferret

Main researcher
Liver Diseases
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Maria del Mar Riveiro Barciela

Maria del Mar Riveiro Barciela

Main researcher
Liver Diseases
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Meritxell Ventura Cots

Meritxell Ventura Cots

Main researcher
Liver Diseases
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Publications

Characterizing Hepatitis Delta in Spain and the gaps in its management.

PMID: 38908682
Journal: Gastroenterologia y Hepatologia
Year: 2024
Reference: Gastroenterol Hepatol. 2024 Jun 20:502222. doi: 10.1016/j.gastrohep.2024.502222.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Arguelles, Marta; Antonio Carrion, Jose; Buti, Maria; Cabezas, Joaquin; Casado, Marta; Castillo, Pilar; Delgado, Merce; Diago, Moises; Diaz-Fontenla, Fernando; Fernandez Marcos, Cristina et al.
DOI: 10.1016/j.gastrohep.2024.502222

Noninvasive Assessment of Portal Hypertension.

PMID: 38945634
Journal: Clinics in Liver Disease
Year: 2024
Reference: Clin Liver Dis. 2024 Aug;28(3):401-415. doi: 10.1016/j.cld.2024.03.010. Epub 2024 May 8.
Impact factor:
Publication type: Paper in international publication
Authors: Aceituno, Laia; Banares, Juan; Genesca, Joan; Pons, Monica et al.
DOI: 10.1016/j.cld.2024.03.010

Performance of spleen stiffness measurement to rule out high-risk varices in patients with porto-sinusoidal vascular disorder.

PMID: 38954825
Journal: HEPATOLOGY
Year: 2024
Reference: Hepatology. 2024 Jul 2. doi: 10.1097/HEP.0000000000001004.
Impact factor:
Publication type: Paper in international publication
Authors: Antonenko, Antonina; Balcar, Lorenz; Berzigotti, Annalisa; Caccia, Riccardo; Capinha, Francisco; Castera, Laurent; Colecchia, Antonio; Dajti, Elton; Elkrief, Laure; Ferreira-Silva, Joel et al.
DOI: 10.1097/HEP.0000000000001004

Fazirsiran for Adults with Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA).

PMID: 38964420
Journal: Gastroenterology
Year: 2024
Reference: Gastroenterology. 2024 Jul 2:S0016-5085(24)05181-3. doi: 10.1053/j.gastro.2024.06.028.
Impact factor:
Publication type: Paper in international publication
Authors: Barjaktarevic, Igor; Brantly, Mark; Chang, Ting; Clark, Virginia C; Corsico, Angelo Guido; Goldklang, Monica; Gray, Meagan; Hamilton, James; Kappe, Naomi; Kuhn, Brooks et al.
DOI: 10.1053/j.gastro.2024.06.028

Quantifying In-Host Quasispecies Evolution.

PMID: 36674827
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Jan 9;24(2):1301. doi: 10.3390/ijms24021301.
Impact factor:
Publication type: Paper in international publication
Authors: Gregori, Josep; Ibanez-Lligona, Marta; Quer, Josep et al.
DOI: 10.3390/ijms24021301

Evaluation of Two Different Strategies for Schistosomiasis Screening in High-Risk Groups in a Non-Endemic Setting.

PMID: 36668951
Journal: Tropical Medicine and Infectious Disease
Year: 2023
Reference: Trop Med Infect Dis. 2023 Jan 6;8(1):44. doi: 10.3390/tropicalmed8010044.
Impact factor:
Publication type: Paper in international publication
Authors: Aznar, Maria Luisa; Bocanegra, Cristina; Bosch-Nicolau, Pau; Espinosa-Pereiro, Juan; Goterris, Lidia; Molina, Israel; Oliveira-Souto, Ines; Pou, Diana; Roade, Luisa; Salvador, Fernando et al.
DOI: 10.3390/tropicalmed8010044

Pseudovesicular appearance in Sweet's syndrome: important yet easily missed - Authors' reply.

PMID: 36641197
Journal: LANCET
Year: 2023
Reference: Lancet. 2023 Jan 14;401(10371):104. doi: 10.1016/S0140-6736(22)02462-X.
Impact factor:
Publication type: Letter or abstract
Authors: Aceituno, Laia; Aleman, Carmen; Banares, Juan; Escobar, Eduardo Dacosta; Jimenez, Alba; Maynard, Avonello et al.
DOI: 10.1016/S0140-6736(22)02462-X

Budesonide as first-line treatment in patients with autoimmune hepatitis seems inferior to standard predni(so)lone administration.

PMID: 36626622
Journal: HEPATOLOGY
Year: 2023
Reference: Hepatology. 2023 Apr 1;77(4):1095-1105. doi: 10.1097/HEP.0000000000000018. Epub 2023 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Navascues, Carmen; Arencibia, Ana; Barreira-Diaz, Ana; Conde, Isabel; Crespo, Javier; Del Barrio, Maria; Diaz-Gonzalez, Alvaro; El Hajra, Ismael; Escude, Laia; Estevez, Pamela et al.
DOI: 10.1097/HEP.0000000000000018

Impact of the COVID-19 pandemic on the care and outcomes of patients with NAFLD-related cirrhosis.

PMID: 36061511
Journal: JHEP Reports
Year: 2022
Reference: JHEP Rep. 2022 Nov;4(11):100574. doi: 10.1016/j.jhepr.2022.100574. Epub 2022 Aug 27.
Impact factor:
Publication type: Paper in international publication
Authors: Banares, Juan; Bassegoda, Octavi; Broquetas, Teresa; Carrion, Jose; Castillo, Joaquin; Espin, Gemma; Gines, Pere; Graupera, Isabel; Manzano-Nunez, Ramiro; Pericas, Juan M et al.
DOI: 10.1016/j.jhepr.2022.100574

Implementation of anti-HDV reflex testing among HBsAg-positive individuals increases testing for hepatitis D.

PMID: 36052219
Journal: JHEP Reports
Year: 2022
Reference: JHEP Rep. 2022 Jul 21;4(10):100547. doi: 10.1016/j.jhepr.2022.100547. eCollection 2022 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Pacin, Beatriz; Palom, Adriana; Rando-Segura, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Vargas, Elena; Vico, Judit et al.
DOI: 10.1016/j.jhepr.2022.100547

New actors come into play against hepatitis delta.

PMID: 36043543
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2022
Reference: Rev Esp Enferm Dig. 2022 Dec;114(12):702-704. doi: 10.17235/reed.2022.9050/2022.
Impact factor:
Publication type: Editorial in national publication
Authors: Buti, Maria; Palom, Adriana; Riveiro-Barciela, Mar et al.
DOI: 10.17235/reed.2022.9050/2022

Severe Impairment of Patient-Reported Outcomes in Patients with Chronic Hepatitis C Virus Infection Seen in Real-World Practices Across the World: Data from the Global Liver Registry.

PMID: 36036096
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2022
Reference: J Viral Hepat. 2022 Nov;29(11):1015-1025. doi: 10.1111/jvh.13741. Epub 2022 Sep 7.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Chan, Wah-Kheong; Duseja, Ajay; El-Kassas, Mohamed; Esmat, Gamal; Fernandez, Marlen I Castellanos; Gordon, Stuart; Hamid, Saeed; Henry, Linda; Isakov, Vasily et al.
DOI: 10.1111/jvh.13741

Overall clinical and economic impact of non-alcoholic fatty liver disease.

PMID: 33222473
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2021
Reference: Rev Esp Enferm Dig. 2021 Jun;113(6):396-403. doi: 10.17235/reed.2020.7238/2020.
Impact factor:
Publication type: Review in international publication
Authors: Aller, Rocio; Augustin, Salvador; Calleja, Jose Luis; Crespo Garcia, Javier; Romero-Gomez, Manuel; Sicras-Mainar, Antoni; Turnes, Juan et al.
DOI: 10.17235/reed.2020.7238/2020

Barriers to linkage to care in hepatitis C patients with substance use disorders and dual diagnoses, despite centralized management.

PMID: 34471422
Journal: Therapeutic Advances in Gastroenterology
Year: 2021
Reference: Therap Adv Gastroenterol. 2021 Aug 27;14:17562848211016563. doi: 10.1177/17562848211016563. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Colom, Joan; Daigre, Constanza; Esteban, Rafael; Grau-Lopez, Lara; Llaneras, Jordi; Marcos-Fosch, Cristina; Martinez-Luna, Nieves; Palma-Alvarez, Raul Felipe; Palma-Alvarez, Raul Felipe et al.
DOI: 10.1177/17562848211016563

A novel model of care for simplified testing of HBV in African communities during the COVID-19 pandemic in Spain.

PMID: 34433852
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Silvia G; Buti, Maria; Fernandez, Emma; Lazarus, Jeffrey V; Lens, Sabela; Nomah, Daniel K; Picchio, Camila A; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco; Rodriguez-Tajes, Sergio et al.
DOI: 10.1038/s41598-021-96350-3

Host-dependent editing of SARS-CoV-2 in COVID-19 patients.

PMID: 34402744
Journal: Emerging Microbes & Infections
Year: 2021
Reference: Emerg Microbes Infect. 2021 Dec;10(1):1777-1789. doi: 10.1080/22221751.2021.1969868.
Impact factor:
Publication type: Paper in international publication
Authors: Abril, Josep Francesc; Andres, Cristina; Anton, Andres; Campos, Carolina; Castillo, Carla; Codina, Maria Gema; Colomer-Castell, Sergi; Cortese, Maria Francesca; Esperalba, Juliana; Esteban, Juan Ignacio et al.
DOI: 10.1080/22221751.2021.1969868

Reply to: "Evaluating the role of transient elastography post chronic hepatitis C treatment to predict hepatocellular carcinoma".

PMID: 32854982
Journal: JOURNAL OF HEPATOLOGY
Year: 2020
Reference: J Hepatol. 2020 Nov;73(5):1289-1290. doi: 10.1016/j.jhep.2020.07.031. Epub 2020 Aug 24.
Impact factor:
Publication type: Letter or abstract
Authors: Genesca, Joan et al.
DOI: 10.1016/j.jhep.2020.07.031

Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure.

PMID: 31857134
Journal: ANTIVIRAL RESEARCH
Year: 2020
Reference: Antiviral Res. 2020 Feb;174:104694. doi: 10.1016/j.antiviral.2019.104694. Epub 2019 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: Acero, Doroteo; Albillos, Agustin; Andrade, Raul Jesus; Antonio Del-Campo, Jose; Arenas, Juan Ignacio; Augustin, Salvador; Baliellas, Carme; Baluja-Pino, Raquel; Barenys, Merce; Bernet, Albert et al.
DOI: 10.1016/j.antiviral.2019.104694

Consensus document of the Spanish Association for Study of the Liver on the treatment of hepatitis B virus infection (2020).

PMID: 32778356
Journal: Gastroenterologia y Hepatologia
Year: 2020
Reference: Gastroenterol Hepatol. 2020 Nov;43(9):559-587. doi: 10.1016/j.gastrohep.2020.03.011. Epub 2020 Aug 7.
Impact factor:
Publication type: Paper in national publication
Authors: Buti, Maria; Esteban, Rafael; Garcia-Samaniego, Javier; Lens, Sabela; Prieto, Martin; Rodriguez, Manuel; Suarez, Emilio et al.
DOI: 10.1016/j.gastrohep.2020.03.011

Steatosis as main determinant of portal hypertension through a restriction of hepatic sinusoidal area in a dietary rat nash model.

PMID: 32770818
Journal: LIVER INTERNATIONAL
Year: 2020
Reference: Liver Int. 2020 Nov;40(11):2732-2743. doi: 10.1111/liv.14632. Epub 2020 Oct 13.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Barbera, Aurora; Bravo, Miren; Garcia-Lezana, Teresa; Genesca, Joan; Gil, Mar; Hide, Diana; Martell, Maria; Raurell, Imma; Salcedo, Maria Teresa et al.
DOI: 10.1111/liv.14632

Sofosbuvir/Velpatasvir for 12 Weeks in Hepatitis C Virus-Infected Patients with End-Stage Renal Disease Undergoing Dialysis.

PMID: 31195062
Journal: JOURNAL OF HEPATOLOGY
Year: 2019
Reference: J Hepatol. 2019 Oct;71(4):660-665. doi: 10.1016/j.jhep.2019.05.028. Epub 2019 Jun 11.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, Kosh; Ampuero, Javier; Ben-Ari, Ziv; Borgia, Sergio M; Brown, Ashley; Bruck, Rafael; Calleja, Jose Luis; Cooper, Curtis; Cramp, Matthew E; Dearden, Janet et al.
DOI: 10.1016/j.jhep.2019.05.028

Recommendations for the detection, diagnosis and follow-up of patients with non-alcoholic fatty liver disease in primary and hospital care.

PMID: 31178295
Journal: MEDICINA CLINICA
Year: 2019
Reference: Med Clin (Barc). 2019 Aug 16;153(4):169-177. doi: 10.1016/j.medcli.2019.01.030. Epub 2019 Jun 6.
Impact factor:
Publication type: Paper in national publication
Authors: Augustin, Salvador; Broquetas, Teresa; Caballeria, Llorenc; Carrion, Jose Antonio; Fernandez-Real, Jose Manuel; Gines, Pere; Goday, Antonio; Graupera, Isabel; Hernandez, Maria Rosa; Morillas, Rosa Maria et al.
DOI: 10.1016/j.medcli.2019.01.030

Decompensated liver disease due to primary hepatic amyloidosis: Is liver transplantation still mandatory?

PMID: 30561765
Journal: HEPATOLOGY
Year: 2019
Reference: Hepatology. 2019 Jun;69(6):2701-2703. doi: 10.1002/hep.30464. Epub 2019 Mar 7.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Castells, Lluis; Esteban, Rafael; Gironella, Merche; Martinez-Valle, Fernando; Merino-Casabiel, Xavier; Riveiro-Barciela, Mar; Salcedo, Maria-Teresa; Senin, Alicia et al.
DOI: 10.1002/hep.30464

Ten-year efficacy and safety of tenofovir disoproxil fumarate treatment for chronic hepatitis B virus infection.

PMID: 31136052
Journal: LIVER INTERNATIONAL
Year: 2019
Reference: Liver Int. 2019 Oct;39(10):1868-1875. doi: 10.1111/liv.14155. Epub 2019 Jul 10.
Impact factor:
Publication type: Paper in international publication
Authors: Buggisch, Peter; Buti-Ferret, Maria; Cathcart, Andrea L; Crans, Gerald; Flaherty, John; Flisiak, Robert; Gaggar, Anuj; Jump, Belinda; Kaita, Kelly; Krastev, Zahari et al.
DOI: 10.1111/liv.14155

Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesis.

PMID: 30068642
Journal: JOURNAL OF VIROLOGY
Year: 2018
Reference: J Virol. 2018 Sep 26;92(20). pii: JVI.01119-18. doi: 10.1128/JVI.01119-18. Print 2018 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Caridi, Flavia; de Avila, Ana Isabel; de la Higuera, Ignacio; Domingo, Esteban; Ferrer-Orta, Cristina; Moreno, Elena; Perales, Celia; Sarafianos, Stefan G; Singh, Kamalendra; Sobrino, Francisco et al.
DOI: 10.1128/JVI.01119-18

Hepatitis B virus: The challenge of an ancient virus with multiple faces and a remarkable replication strategy.

PMID: 30059722
Journal: ANTIVIRAL RESEARCH
Year: 2018
Reference: Antiviral Res. 2018 Oct;158:34-44. doi: 10.1016/j.antiviral.2018.07.019. Epub 2018 Jul 29.
Impact factor:
Publication type: Review in international publication
Authors: Buti, Maria; Caballero, Andrea; Rodriguez-Frias, Francisco; Tabernero, David et al.
DOI: 10.1016/j.antiviral.2018.07.019

No Resistance to Tenofovir Alafenamide Detected Through 96 Weeks of Treatment in Patients with Chronic Hepatitis B.

PMID: 30038044
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2018
Reference: Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: AAC.01064-18. doi: 10.1128/AAC.01064-18. Print 2018 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Bhardwaj, Neeru; Buti, Maria; Cathcart, Andrea L; Chan, Henry Lik-Yuen; Chang, Silvia; Cox, Stephanie; Flaherty, John F; Gaggar, Anuj; Izumi, Namiki; Kitrinos, Kathryn M et al.
DOI: 10.1128/AAC.01064-18

Should prophylactic embolization of spontaneous portosystemic shunts be routinely performed during transjugular intrahepatic portosystemic shunt placement?

PMID: 30005961
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2018
Reference: Dig Liver Dis. 2018 Dec;50(12):1324-1326. doi: 10.1016/j.dld.2018.06.013. Epub 2018 Jun 28.
Impact factor:
Publication type: Paper in international publication
Authors: Genesca, Joan; Simon-Talero, Macarena; Vidal-Gonzalez, Judit et al.
DOI: 10.1016/j.dld.2018.06.013

Rapid liver and spleen stiffness improvement in compensated advanced chronic liver disease patients treated with oral antivirals.

PMID: 28835776
Journal: Therapeutic Advances in Gastroenterology
Year: 2017
Reference: Therap Adv Gastroenterol. 2017 Aug;10(8):619-629. doi: 10.1177/1756283X17715198. Epub 2017 Jun 27.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Esteban, Rafael; Genesca, Joan; Pons, Monica; Riveiro-Barciela, Mar; Santos, Begona; Simon-Talero, Macarena; Ventura-Cots, Meritxell et al.
DOI: 10.1177/1756283X17715198

Safety and efficacy of a fixed-dose combination regimen of grazoprevir, ruzasvir, and uprifosbuvir with or without ribavirin in participants with and without cirrhosis with chronic hepatitis C virus genotype 1, 2, or 3 infection (C-CREST-1 and C-CREST-2, part B): two randomised, phase 2, open-label trials.

PMID: 28802814
Journal: The lancet. Gastroenterology & hepatology
Year: 2017
Reference: Lancet Gastroenterol Hepatol. 2017 Nov;2(11):814-823. doi: 10.1016/S2468-1253(17)30163-2. Epub 2017 Aug 10.
Impact factor:
Publication type: Clinical Trials
Authors: Almasio, Piero L; Barr, Eliav; Bruno, Savino; Buti, Maria; Butterton, Joan R; Dutko, Frank J; Fernsler, Doreen; Gao, Wei; Grandhi, Anjana; Hassanein, Tarek I et al.
DOI: 10.1016/S2468-1253(17)30163-2

Non-alcoholic fatty liver disease: A poorly known pandemic.

PMID: 28751080
Journal: MEDICINA CLINICA
Year: 2017
Reference: Med Clin (Barc). 2017 Dec 20;149(12):542-548. doi: 10.1016/j.medcli.2017.06.026. Epub 2017 Jul 24.
Impact factor:
Publication type: Review in national publication
Authors: Agustin, Salvador; Caballeria, Juan; Graupera, Isabel et al.
DOI: 10.1016/j.medcli.2017.06.026

Inferior Cava Vein Syndrome and Heart Compression Due to a Giant Liver Cyst.

PMID: 28725071
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2017
Reference: Am J Gastroenterol. 2017 Jul;112(7):984. doi: 10.1038/ajg.2017.132.
Impact factor:
Publication type: Paper in international publication
Authors: Casabiel, Xavier Merino; Lazaro, Jose Luis; Nicolau, Pau Bosch; Riveiro-Barciela, Mar; Viladomiu, Lluis et al.
DOI: 10.1038/ajg.2017.132

Isolated bilateral Tapia's syndrome after liver transplantation: A case report and review of the literature.

PMID: 28083087
Journal:
Year: 2016
Reference: World J Hepatol. 2016 Dec 28;8(36):1637-1644. doi: 10.4254/wjh.v8.i36.1637.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, Itxarone; Caralt, Mireia; Castells, Lluis; Charco, Ramon; Dopazo, Cristina; Gantxegi, Amaia; Pando, Elisabeth; Pando, Elisabeth et al.
DOI: 10.4254/wjh.v8.i36.1637

Management of direct antiviral agent failures.

PMID: 28081594
Journal: Clinical and molecular hepatology
Year: 2016
Reference: Clin Mol Hepatol. 2016 Dec;22(4):432-438. doi: 10.3350/cmh.2016.0107. Epub 2016 Dec 25.
Impact factor:
Publication type: Review in national publication
Authors: Buti, Maria; Esteban, Rafael et al.
DOI: 10.3350/cmh.2016.0107

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

PMID: 27959928
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Dec 13;11(12):e0166902. doi: 10.1371/journal.pone.0166902. eCollection 2016.
Impact factor:
Publication type: Paper in international publication
Authors: Abia, David; Alcami, Jose; Briones, Carlos; Domingo, Esteban; Dos Santos, Helena G; Fernandez-Algar, Maria; Garcia-Perez, Javier; Garrido, Patricia; Martin, Veronica; Moreno, Miguel et al.
DOI: 10.1371/journal.pone.0166902

Efficacy and Safety of Therapy With Simeprevir and Sofosbuvir in Liver Transplant Recipients Infected by Hepatitis C Virus Genotype 4: Cohort Spanish Society of Liver Transplantation Cohort.

PMID: 27932134
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2016
Reference: Transplant Proc. 2016 Nov;48(9):3013-3016. doi: 10.1016/j.transproceed.2016.08.034.
Impact factor:
Publication type: Paper in international publication
Authors: Arencibia, Ana; Bartolome, Sonia Pascual; Castells, L; Cristobal, Mario Romero; Cuervas-Mons, Valentin; Espinosa, Maria Dolores; Fernandez Vazquez, I; Garcia, Emilio Fabrega; Gonzalez Dieguez, Maria Luisa; Herrero, J I et al.
DOI: 10.1016/j.transproceed.2016.08.034

Hepatitis B e antigen status and hepatitis B DNA levels in women of childbearing age with chronic hepatitis B infection screening for clinical trials.

PMID: 25789483
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Mar 19;10(3):e0121632. doi: 10.1371/journal.pone.0121632. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Dinh, Phillip; Fung, Scott; Gordon, Stuart C; Marcellin, Patrick; Martins, Eduardo Bruno; Tran, Tram T; Yee, Leland et al.
DOI: 10.1371/journal.pone.0121632

Long-term clinical outcomes in cirrhotic chronic hepatitis B patients treated with tenofovir disoproxil fumarate for up to 5 years.

PMID: 25788199
Journal: HEPATOL INT
Year: 2015
Reference: Hepatol Int. 2015 Apr;9(2):243-50. doi: 10.1007/s12072-015-9614-4. Epub 2015 Mar 13.
Impact factor:
Publication type: Paper in international publication
Authors: Afdhal, Nezam H; Bornstein, Jeffrey D; Buti, Maria; Dinh, Phillip; Flaherty, John F; Flisiak, Robert; Fung, Scott; Gane, Edward; George, Jacob; Gurel, Selim et al.
DOI: 10.1007/s12072-015-9614-4

An OPTIMIZE study retrospective analysis for management of telaprevir-treated hepatitis C virus (HCV)-infected patients by use of the Abbott RealTime HCV RNA assay.

PMID: 25653396
Journal: J CLIN MICROBIOL
Year: 2015
Reference: J Clin Microbiol. 2015 Apr;53(4):1264-9. doi: 10.1128/JCM.03030-14. Epub 2015 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Cloherty, Gavin; De Meyer, Sandra; Dierynck, Inge; Ghys, Anne; Janssen, Katrien; Luo, Donghan; Picchio, Gaston; Sarrazin, Christoph; Witek, James et al.
DOI: 10.1128/JCM.03030-14

Hepatitis B virus quasispecies evolution after liver transplantation in patients under long-term lamivudine prophylaxis with or without hepatitis B immune globulin.

PMID: 25641570
Journal: TRANSPL INFECT DIS
Year: 2015
Reference: Transpl Infect Dis. 2015 Apr;17(2):208-20. doi: 10.1111/tid.12360.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, M; Casafont, F; Casillas, R; Castells, L; Esteban, R; Gonzalez, A; Herrero, J I; Homs, M; Mas, A; Miras, M et al.
DOI: 10.1111/tid.12360

Etiology and mortality of spontaneous bacterial peritonitis in liver transplant recipients: A cohort study.

PMID: 24723503
Journal: LIVER TRANSPLANTATION
Year: 2014
Reference: Liver Transpl. 2014 Jul;20(7):856-63. doi: 10.1002/lt.23889. Epub 2014 May 26.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, Itxarone; Campos-Varela, Isabel; Castells, Lluis; Gavalda, Joan; Len, Oscar; Pahissa, Albert; Perez-Cameo, Cristina; Vargas, Victor et al.
DOI: 10.1002/lt.23889

Historical epidemiology of hepatitis C virus (HCV) in selected countries.

PMID: 24713004
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2014
Reference: J Viral Hepat. 2014 May;21 Suppl 1:5-33. doi: 10.1111/jvh.12247.
Impact factor:
Publication type: Paper in international publication
Authors: Akarca, U; Aleman, S; Balik, I; Berg, T; Bihl, F; Bilodeau, M; Blasco, A J; Brandao Mello, C E; Bruggmann, P; Buti, M et al.
DOI: 10.1111/jvh.12247

Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection.

PMID: 24134179
Journal: LIVER INTERNATIONAL
Year: 2014
Reference: Liver Int. 2014 Jul;34(6):896-906. doi: 10.1111/liv.12362. Epub 2013 Nov 20.
Impact factor:
Publication type: Paper in international publication
Authors: Bes, Marta; Casillas, Rosario; Cubero, Maria; Domingo, Esteban; Esteban, Juan I; Esteban, Rafael; Garcia-Cehic, Damir; Gregori, Josep; Guardia, Jaume; Ortega, Israel et al.
DOI: 10.1111/liv.12362

Indocyanine green plasma disappearance rate: a new tool for the classification of paediatric patients with acute liver failure.

PMID: 24112412
Journal: LIVER INTERNATIONAL
Year: 2014
Reference: Liver Int. 2014 May;34(5):689-94. doi: 10.1111/liv.12298. Epub 2013 Sep 24.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, Itxarone; Bueno, Javier; Castells, Lluis; Charco, Ramon; Dopazo, Cristina; Miserachs, Mar; Ortega, Juan; Quintero, Jesus et al.
DOI: 10.1111/liv.12298

Brain magnetic resonance spectroscopy in episodic hepatic encephalopathy.

PMID: 23168529
Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Year: 2013
Reference: J Cereb Blood Flow Metab. 2013 Feb;33(2):272-7. doi: 10.1038/jcbfm.2012.173. Epub 2012 Nov 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Juli; Chavarria, Laia; Cordoba, Juan; Garcia-Martinez, Rita; Ramirez, Clara; Rovira, Alex; Simon-Talero, Macarena; Torrens, Maria; Vargas, Victor; Ventura-Cots, Meritxell et al.
DOI: 10.1038/jcbfm.2012.173

Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study.

PMID: 23234725
Journal: LANCET
Year: 2013
Reference: Lancet. 2013 Feb 9;381(9865):468-75. doi: 10.1016/S0140-6736(12)61425-1. Epub 2012 Dec 10.
Impact factor:
Publication type: Paper in international publication
Authors: Afdhal, Nezam; Bornstein, Jeffrey D; Buti, Maria; Flaherty, John F; Gane, Edward; Germanidis, George; Heathcote, E Jenny; Jacobson, Ira M; Kitrinos, Kathryn M; Marcellin, Patrick et al.
DOI: 10.1016/S0140-6736(12)61425-1

Falls and cognitive dysfunction impair health-related quality of life in patients with cirrhosis.

PMID: 22954704
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2013
Reference: Eur J Gastroenterol Hepatol. 2013 Jan;25(1):77-84. doi: 10.1097/MEG.0b013e3283589f49.
Impact factor:
Publication type: Paper in international publication
Authors: Cordoba, Juan; Guarner, Carlos; Roman, Eva; Soriano, German; Torrens, Maria et al.
DOI: 10.1097/MEG.0b013e3283589f49

Unconventional secretion is a major contributor of cancer cell line secretomes.

PMID: 23268930
Journal: MOLECULAR & CELLULAR PROTEOMICS
Year: 2013
Reference: Mol Cell Proteomics. 2013 May;12(5):1046-60. doi: 10.1074/mcp.M112.021618. Epub 2012 Dec 26.
Impact factor:
Publication type: Paper in international publication
Authors: Baselga, Jose; Gregori, Josep; Mendez, Olga; Salvans, Candida; Villanueva, Josep; Villarreal, Laura et al.
DOI: 10.1074/mcp.M112.021618

Entecavir Plus Tenofovir Combination as Rescue Therapy in Pretreated Chronic Hepatitis B Patients. An International Multicenter Cohort Study.

PMID: 22037226
Journal: JOURNAL OF HEPATOLOGY
Year: 2012
Reference: J Hepatol. 2012 Mar;56(3):520-6. Epub 2011 Oct 26.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.jhep.2011.09.018

Long-term follow-up of hemodynamic responders to pharmacological therapy after variceal bleeding.

PMID: 22378235
Journal: HEPATOLOGY
Year: 2012
Reference: Hepatology. 2012 Aug;56(2):706-14. doi: 10.1002/hep.25686. Epub 2012 Jul 6.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1002/hep.25686

[Hepatitis E: Molecular virology, epidemiology and pathogenesis.]

PMID: 22386306
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2012
Reference: Enferm Infecc Microbiol Clin. 2012 Dec;30(10):624-34. doi: 10.1016/j.eimc.2012.01.014. Epub 2012 Mar 3.
Impact factor:
Publication type: Review in national publication
Authors: ; ; et al.
DOI: 10.1016/j.eimc.2012.01.014

Incidence, characteristics and risk factors of marked hyperbilirubinemia after allogeneic hematopoietic cell transplantation with reduced-intensity conditioning.

PMID: 22388280
Journal: BONE MARROW TRANSPLANTATION
Year: 2012
Reference: Bone Marrow Transplant. 2012 Oct;47(10):1343-9. doi: 10.1038/bmt.2012.25. Epub 2012 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/bmt.2012.25

Diagnosis of Alpha-1 Antitrypsin Deficiency: Limitations of Rapid Diagnostic Laboratory Tests.

PMID: 21470755
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2011
Reference: Arch Bronconeumol. 2011 Aug;47(8):415-7. Epub 2011 Apr 5.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.arbres.2011.02.005

Evolution of biliary complications after liver transplantation: a single European series.

PMID: 21486589
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2011
Reference: Transplant Proc. 2011 Apr;43(3):745-8.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, I; Caralt, M; Castells, L; Charco, R; Diez, I; Dopazo, C; Gantxegi, A; Lazaro, J L; Llopart, L; Perez, M et al.
DOI: 10.1016/j.transproceed.2011.01.102

Does pre-liver transplant HBV DNA level affect HBV recurrence or survival in liver transplant recipients receiving HBIg and nucleos(t)ide analogues?

PMID: 21502680
Journal: Annals of Hepatology
Year: 2011
Reference: Ann Hepatol. 2011 Apr 1;10(2):180-7.
Impact factor:
Publication type: Paper in international publication
Authors: Bilbao, Itxarone; Buti, Maria; Campos-Varela, Isabel; Castells, Lluis; Charco, Ramon; Esteban, Rafael; Guardia, Jaime; Jardi, Rosendo; Rodriguez-Frias, Francisco; Vargas, Victor et al.
DOI:

Minimal Hepatic Encephalopathy Is Associated With Falls.

PMID: 20978484
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 Mar;106(3):476-82. Epub 2010 Oct 26.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1038/ajg.2010.413

Infrequent detection of hepatitis E virus RNA in pregnant women with hepatitis E virus antibodies in Spain.

PMID: 20629948
Journal: LIVER INTERNATIONAL
Year: 2010
Reference: Liver Int. 2010 Nov;30(10):1549-51. doi: 10.1111/j.1478-3231.2010.02304.x.
Impact factor: 2.987
Publication type: Letter or abstract
Authors: , , , , , , , , et al.
DOI: 10.1111/j.1478-3231.2010.02304.x

The use of malaria antibody tests in the prevention of transfusion-transmitted malaria.

PMID: 20136789
Journal: VOX SANGUINIS
Year: 2010
Reference: Vox Sang. 2010 Apr;98(3 Pt 2):468-78. Epub 2010 Jan 28.
Impact factor: 2.585
Publication type: Paper in international publication
Authors: Reesink, H W, Panzer, S, Wendel, S, Levi, J E, Ullum, H, Ekblom-Kullberg, S, Seifried, E, Schmidt, M, Shinar, E, Prati, D et al.
DOI: 10.1111/j.1423-0410.2009.01301.x

Inventory management.

PMID: 20432515
Journal: VOX SANGUINIS
Year: 2010
Reference: Vox Sang. 2010 Apr;98(3 Pt 1):e295-363.
Impact factor: 2.585
Publication type: Letter or abstract
Authors: Sarappa, C, Devine, D V, Sher, G D, Reesink, H W, Panzer, S, Hetzel, P A S, Wong, J K, Horvath, M, Leitner, G C, Schennach, H et al.
DOI:

Laboratory testing of individuals with severe alpha1-antitrypsin deficiency in three European centres.

PMID: 20436173
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2010
Reference: Eur Respir J. 2010 May;35(5):960-8.
Impact factor: 5.527
Publication type: Paper in international publication
Authors: Luisetti, M, Bals, R, Rodriguez-Frias, F, Jardi, R, Herr, C, Miravitlles, M, Ferrarotti, I et al.
DOI: 10.1183/09031936.00069709

Early HBeAg loss during peginterferon alpha-2b therapy predicts HBsAg loss: results of a long-term follow-up study in chronic hepatitis B patients.

PMID: 19584831
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2009
Reference: Am J Gastroenterol. 2009 Oct;104(10):2449-57.
Impact factor:
Publication type: Paper in international publication
Authors: Buster, Erik H C J; Buti, Maria; de Vries, Richard A; Flink, Hajo J; Gerken, Guido; Hansen, Bettina E; Heathcote, E Jenny; Janssen, Harry L A; Kitis, George E; Sharmila, Sachithanandan et al.
DOI: 10.1038/ajg.2009.371

Hepatitis C virus (HCV)-specific T-cell responses among recombinant immunoblot assay-3-indeterminate blood donors: a confirmatory evidence of HCV exposure.

PMID: 19222816
Journal: TRANSFUSION
Year: 2009
Reference: Transfusion. 2009 Jul;49(7):1296-305.
Impact factor:
Publication type: Paper in international publication
Authors: Bes, Marta; Casamitjana, Natalia; Cubero, Maria; Esteban, Juan Ignacio; Guardia, Jaime; Piron, Maria; Puig, Lluis; Quer, Josep; Sauleda, Silvia et al.
DOI: 10.1111/j.1537-2995.2009.02103.x

Successful use of entecavir for a severe case of reactivation of hepatitis B virus following polychemotherapy containing rituximab.

PMID: 19836097
Journal: JOURNAL OF HEPATOLOGY
Year: 2009
Reference: J Hepatol. 2009 Dec;51(6):1091-6.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.jhep.2009.07.012

Response-guided therapy for chronic hepatitis C virus infection in patients coinfected with HIV: a pilot trial.

PMID: 19275492
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2009
Reference: Clin Infect Dis. 2009 Apr 15;48(8):1152-9.
Impact factor:
Publication type: Paper in international publication
Authors: Carbonell, Judit; Crespo, Manuel; Curran, Adria; Esteban, Juan I; Esteban, Rafael; Falco, Vicenc; Imaz, Arkaitz; Jardi, Rosend; Ocana, Inma; Pahissa, Albert et al.
DOI: 10.1086/597470

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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