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Maternal and Fetal Medicine

The Maternal and Fetal Medicine Research Group has been recognized by AGAUR as a consolidated research group. It is a multidisciplinary team which integrates different knowledge areas in basic and clinical research. Basic research aims to identify new diagnostic and therapeutic tools in maternal and fetal pathologies, while clinical research intends to apply these tools in clinical practice.

The group coordinator is Dr. Elena Carreras, awarded with the professional excellence award by the College of Physicians and Surgeons of Barcelona in 2018.

The group has different investigation areas:

  • Preterm delivery and vaginal microbiota
  • Placental insufficiency    
  • Fetal spina bifida prenatal surgical treatment 
  • Obstetric ultrasound, fetal medicine and fetal therapy
  • Maternal and obstetric pathology and infections during gestation

Team

Maite Avilés García

Maite Avilés García

Predoctoral researcher
Maternal and Fetal Medicine
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Manuel Casellas Caro

Manuel Casellas Caro

Main researcher
Maternal and Fetal Medicine
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Pablo García Manau

Pablo García Manau

Predoctoral researcher
Maternal and Fetal Medicine
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Erika Bonacina

Erika Bonacina

Main researcher
Maternal and Fetal Medicine
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Brigidi , Serena

Brigidi , Serena

Research technician
Maternal and Fetal Medicine
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Moreno Perez, Elena

Moreno Perez, Elena

Predoctoral researcher
Maternal and Fetal Medicine
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Maite Avilés García

Maite Avilés García

Predoctoral researcher
Maternal and Fetal Medicine
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Manuel Casellas Caro

Manuel Casellas Caro

Main researcher
Maternal and Fetal Medicine
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Pablo García Manau

Pablo García Manau

Predoctoral researcher
Maternal and Fetal Medicine
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Erika Bonacina

Erika Bonacina

Main researcher
Maternal and Fetal Medicine
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Brigidi , Serena

Brigidi , Serena

Research technician
Maternal and Fetal Medicine
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Moreno Perez, Elena

Moreno Perez, Elena

Predoctoral researcher
Maternal and Fetal Medicine
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Research lines

Prenatal mielomeningocele repair


IP: Silvia Arévalo Martínez, Nerea Maiz Elizaran, Elena Carreras Moratonas, Carlota Rodó Rodríguez

Preterm birth: Prediction and Prevention


IP: Preterm birth: Prediction and Prevention

Projects

Impact of COVID-19 on male reproductive health

IP: Melchor Carbonell Socias
Collaborators: Julio Herrero García, Nerea Maiz Elizaran, Anna Suy Franch, Maria del Pilar Reimundo Diaz-Fierros
Funding agency: Fundació La Marató de TV3
Funding: 49988.75
Reference: 202128-32
Duration: 20/10/2021 - 19/10/2024

Cribado de preeclampsia en la gestación gemelar

IP: Carlota Rodó Rodríguez
Collaborators: Pablo García Manau, Berta Serrano Sanchez, Francisco Barranco Martinez, Mireia Armengol Alsina
Funding agency: Instituto de Salud Carlos III
Funding: 162140
Reference: PI21/00601
Duration: 01/01/2022 - 31/12/2024

Estudio sobre la transferencia materno-filial de ¿9- tetrahidrocannabidol (THC) a través de leche materna en mujeres postparto con consumo habitual de cannabis. Correlación entre muestras de leche materna, orina y saliva

IP: Constanza Daigre Blanco
Collaborators: Maia Brik Spinelli
Funding agency: Ministerio Sanidad
Funding: 35519
Reference: 2021I047
Duration: 22/12/2021 - 21/12/2024

Publications

Consensus protocols for management of early and late twin-twin transfusion syndrome: Delphi study.

PMID: 37553800
Journal: ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Year: 2023
Reference: Ultrasound Obstet Gynecol. 2023 Aug 8. doi: 10.1002/uog.27446.
Impact factor:
Publication type: Paper in international publication
Authors: Bennasar Sans, M; Carreras, E; Chmait, R; Emery, S P; Habli, M; Hecher, K; Ishii, K; Javinani, A; Johnson, A; Khalil, A et al.
DOI: 10.1002/uog.27446

Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia: Post-hoc analysis of StopPRE trial.

PMID: 37555464
Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Year: 2023
Reference: BJOG. 2023 Aug 9. doi: 10.1111/1471-0528.17631.
Impact factor:
Publication type: Paper in international publication
Authors: Alsius, Merce; Bonacina, Erika; Caamina, Sara; Carreras, Elena; Castillo-Ribelles, Laura; de Mingo, Laura; Diaz, Sonia; Garcia, Esperanza; Garcia-Manau, Pablo; Lopez, Monica et al.
DOI: 10.1111/1471-0528.17631

Ruptured saccular limited dorsal myeloschisis: good indication for fetal repair.

PMID: 37606294
Journal: ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Year: 2023
Reference: Ultrasound Obstet Gynecol. 2023 Aug 22. doi: 10.1002/uog.27457.
Impact factor:
Publication type: Letter or abstract
Authors: Arevalo, S; Carreras, E; Gine, C; Lopez, M; Maiz, N; Rodo, C et al.
DOI: 10.1002/uog.27457

Validating a machine-learning model for first-trimester prediction of pre-eclampsia using the cohort from the PREVAL study.

PMID: 37698356
Journal: ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Year: 2023
Reference: Ultrasound Obstet Gynecol. 2023 Sep 12. doi: 10.1002/uog.27478.
Impact factor:
Publication type: Paper in international publication
Authors: Adiego, B; Ansbacher-Feldman, Z; Cuenca-Gomez, D; de Paco Matallana, C; Diaz, C; Diaz, C; Gil, M M; Louzoun, Y; Martin-Alonso, R; Meiri, H et al.
DOI: 10.1002/uog.27478

Applying reflective multicriteria decision analysis to understand the value of therapeutic alternatives in the management of gestational and peripartum anaemia in Spain.

PMID: 35216553
Journal: BMC Pregnancy and Childbirth
Year: 2022
Reference: BMC Pregnancy Childbirth. 2022 Feb 25;22(1):157. doi: 10.1186/s12884-022-04481-w.
Impact factor: 3.007
Publication type: Paper in international publication
Authors: Casellas Caro, Manel, Hidalgo, Maria Jesus Cancelo, Garcia-Erce, Jose Antonio, Baquero Ubeda, Jose Luis, Torras Boatella, Maria Gloria, Gredilla Diaz, Elena, Ruano Encinar, Margarita, Martin Bayon, Israel, Nicolas Pico, Jordi, Arjona Berral, Jose Eduardo et al.
DOI: 10.1186/s12884-022-04481-w

Respiratory Syncytial Virus Infections in Young Children Presenting to Primary Care in Catalonia During the COVID-19 Pandemic.

PMID: 34922377
Journal: Journal of the Pediatric Infectious Diseases Socie
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 Feb 23;11(2):69-72. doi: 10.1093/jpids/piab121.
Impact factor: 3.164
Publication type: Paper in international publication
Authors: Coma, Ermengol, Vila, Jorgina, Mendez-Boo, Leonardo, Anton, Andres, Mora, Nuria, Fina, Francesc, Fabregas, Mireia, Medina, Manuel et al.
DOI: 10.1093/jpids/piab121

Menopause and multiple sclerosis: Influence on prognosis and role of disease-modifying drugs and hormonal replacement therapy.

PMID: 32856989
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Feb;28(2):173-182. doi: 10.1177/1352458520952022. Epub 2020 Aug 28.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Midaglia, Luciana, Otero, Susana, Baro, Francesc, Montalban, Xavier, Tintore, Mar et al.
DOI: 10.1177/1352458520952022

Diagnostic accuracy of the Gaussian first-trimester combined screening for preeclampsia to predict SGA neonates.

PMID: 33724448
Journal: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
Year: 2022
Reference: Int J Gynaecol Obstet. 2022 Feb;156(2):322-330. doi: 10.1002/ijgo.13673. Epub 2021 Mar 31.
Impact factor: 3.561
Publication type: Paper in international publication
Authors: Mendoza, Manel, Serrano, Berta, Bonacina, Erika, Capote, Sira, Garcia-Manau, Pablo, Murcia, Maria Teresa, Barberan, Lidia, Miguez, Marta, Carreras, Elena, Regincos, Laia et al.
DOI: 10.1002/ijgo.13673

Importance of Enhanced Recovery After Surgery (ERAS) Protocol Compliance for Length of Stay in Ovarian Cancer Surgery.

PMID: 34091804
Journal: ANNALS OF SURGICAL ONCOLOGY
Year: 2021
Reference: Ann Surg Oncol. 2021 Dec;28(13):8979-8986. doi: 10.1245/s10434-021-10228-2. Epub 2021 Jun 6.
Impact factor: 5.344
Publication type: Paper in international publication
Authors: Gil-Moreno, Antonio, Nelson, Gregg, Bradbury, Melissa, Gutierrez-Barcelo, Pilar, Serrano, Monica Pamies, Sanchez-Iglesias, Jose Luis, Gomez-Hidalgo, Natalia R, Perez-Benavente, Asuncion, Carbonell-Socias, Melchor, Manrique-Munoz, Susana et al.
DOI: 10.1245/s10434-021-10228-2

Experience of 300 cases of prenatal fetoscopic open spina bifida repair: Report of the International Fetoscopic Neural Tube Defect Repair Consortium.

PMID: 34089698
Journal: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Year: 2021
Reference: Am J Obstet Gynecol. 2021 Dec;225(6):678.e1-678.e11. doi: 10.1016/j.ajog.2021.05.044. Epub 2021 Jun 3.
Impact factor: 8.661
Publication type: Paper in international publication
Authors: Sanz Cortes, Magdalena, Chmait, Ramen H, Lapa, Denise A, Belfort, Michael A, Carreras, Elena, Miller, Jena L, Brawura Biskupski Samaha, Robert, Sepulveda Gonzalez, Gerardo, Gielchinsky, Yuval, Yamamoto, Masami et al.
DOI: 10.1016/j.ajog.2021.05.044

Diffuse trophoblast damage is the hallmark of SARS-CoV-2-associated fetal demise.

PMID: 34006935
Journal: MODERN PATHOLOGY
Year: 2021
Reference: Mod Pathol. 2021 Sep;34(9):1704-1709. doi: 10.1038/s41379-021-00827-5. Epub 2021 May 18.
Impact factor: 7.842
Publication type: Paper in international publication
Authors: Serrano, Berta, Garrido-Pontnou, Marta, Navarro, Alexandra, Camacho, Jessica, Crispi, Fatima, Alguacil-Guillen, Marina, Moreno-Baro, Anna, Hernandez-Losa, Javier, Sese, Marta, Ramon Y Cajal, Santiago et al.
DOI: 10.1038/s41379-021-00827-5

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study.

PMID: 33885740
Journal: JAMA Pediatrics
Year: 2021
Reference: JAMA Pediatr. 2021 Aug 1;175(8):817-826. doi: 10.1001/jamapediatrics.2021.1050.
Impact factor: 16.193
Publication type: Paper in international publication
Authors: Villar, Jose, Ariff, Shabina, Gunier, Robert B, Thiruvengadam, Ramachandran, Rauch, Stephen, Kholin, Alexey, Roggero, Paola, Prefumo, Federico, do Vale, Marynea Silva, Cardona-Perez, Jorge Arturo et al.
DOI: 10.1001/jamapediatrics.2021.1050

Preeclampsia-like syndrome induced by severe COVID-19: a prospective observational study.

PMID: 32479682
Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Year: 2020
Reference: BJOG. 2020 Oct;127(11):1374-1380. doi: 10.1111/1471-0528.16339. Epub 2020 Jun 21.
Impact factor: 4.663
Publication type: Paper in international publication
Authors: Serrano, Berta, Lopez-Martinez, Rosa Maria, Balcells, Joan, Fernandez-Hidalgo, Nuria, Carreras, Elena, Suy, Anna, Garcia-Manau, Pablo, Rodo, Carlota, Garcia-Ruiz, Itziar, Mendoza, Manel et al.
DOI: 10.1111/1471-0528.16339

Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

PMID: 32456489
Journal: HYPERTENSION IN PREGNANCY
Year: 2020
Reference: Hypertens Pregnancy. 2020 Aug;39(3):361-369. doi: 10.1080/10641955.2020.1769645. Epub 2020 May 26.
Impact factor: 1.787
Publication type: Paper in international publication
Authors: Ruano, Rodrigo, Kilby, Mark D, Carreras Moratonas, Elena, Suy, Anna, Picone, Olivier, Teles Abrao Trad, Ayssa, Ibirogba, Eniola R, Elrefaei, Amro, Narang, Kavita, Tonni, Gabriele et al.
DOI: 10.1080/10641955.2020.1769645

SARS-CoV-2 in Pregnancy: A Comprehensive Summary of Current Guidelines.

PMID: 32443538
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 May 18;9(5). pii: jcm9051521. doi: 10.3390/jcm9051521.
Impact factor: 3.303
Publication type: Review in international publication
Authors: Narang, Kavita, Ibirogba, Eniola R, Elrefaei, Amro, Trad, Ayssa Teles Abrao, Theiler, Regan, Nomura, Roseli, Picone, Olivier, Escuriet, Ramon, Suy, Anna, Carreras, Elena et al.
DOI: 10.3390/jcm9051521

Clinical Outcomes of a Zika Virus Mother-Child Pair Cohort in Spain.

PMID: 32392815
Journal: Pathogens
Year: 2020
Reference: Pathogens. 2020 May 7;9(5). pii: pathogens9050352. doi: 10.3390/pathogens9050352.
Impact factor: 3.018
Publication type: Paper in international publication
Authors: Soler-Palacin, Pere, Espiau, Maria, Salazar, Ainara, Guarch-Ibanez, Borja, Vazquez, Ana, Navarro-Moron, Juan, Ramos-Amador, Jose-Tomas, Martin-Nalda, Andrea, Duenas, Eva, Blazquez-Gamero, Daniel et al.
DOI: 10.3390/pathogens9050352

Multicenter prospective clinical study to evaluate children short-term neurodevelopmental outcome in congenital heart disease (children NEURO-HEART): study protocol.

PMID: 31506079
Journal: BMC Pediatrics
Year: 2019
Reference: BMC Pediatr. 2019 Sep 10;19(1):326. doi: 10.1186/s12887-019-1689-y.
Impact factor: 1.983
Publication type: Paper in international publication
Authors: Bartha, J M, Galindo, A, Martinez, J M, Gomez-Roig, L, Crispi, F, Gomez, O, Carreras, E, Cabero, L, Gratacos, E, Llurba, E et al.
DOI: 10.1186/s12887-019-1689-y

Clinical management of early-stage cervical cancer: The role of sentinel lymph node biopsy in tumors </=2cm.

PMID: 31419693
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2019
Reference: Eur J Obstet Gynecol Reprod Biol. 2019 Oct;241:30-34. doi: 10.1016/j.ejogrb.2019.07.038. Epub 2019 Aug 7.
Impact factor: 2.024
Publication type: Paper in international publication
Authors: Diaz-Feijoo, Berta, Temprana-Salvador, Jordi, Franco-Camps, Silvia, Manrique, Susana, Colas, Eva, Perez-Benavente, Asuncion, Gil-Moreno, Antonio et al.
DOI: 10.1016/j.ejogrb.2019.07.038

Maternal Satisfaction with Healthcare after Perinatal Loss in Monochorionic Twin Pregnancy.

PMID: 31416177
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Aug 14;8(8). pii: jcm8081213. doi: 10.3390/jcm8081213.
Impact factor: 5.688
Publication type: Paper in international publication
Authors: Druguet, Monica, Nuno, Laura, Rodo, Carlota, Arevalo, Silvia, Carreras, Elena, Gomez-Benito, Juana et al.
DOI: 10.3390/jcm8081213

The high genetic similarity between rhinoviruses and enteroviruses remains as a pitfall for molecular diagnostic tools: A three-year overview.

PMID: 31401308
Journal: INFECTION GENETICS AND EVOLUTION
Year: 2019
Reference: Infect Genet Evol. 2019 Nov;75:103996. doi: 10.1016/j.meegid.2019.103996. Epub 2019 Aug 8.
Impact factor: 2.611
Publication type: Paper in international publication
Authors: Vila, Jorgina, Esperalba, Juliana, Trejo-Zahinos, Jesus, Codina, Maria Gema, Martin, Maria Carmen, Fuentes, Francisco, Rubio, Susana, Pumarola, Tomas, Anton, Andres, Pinana, Maria et al.
DOI: 10.1016/j.meegid.2019.103996

Predictors of obstetric complications in women with heart disease.

PMID: 26371393
Journal: Journal of Maternal-Fetal & Neonatal Medicine
Year: 2016
Reference: J Matern Fetal Neonatal Med. 2016 Jul;29(14):2306-11. doi: 10.3109/14767058.2015.1085012. Epub 2015 Sep 15.
Impact factor: 1.674
Publication type: Paper in international publication
Authors: Goya, Maria, Casellas, Manel, Merced, Carme, Pijuan-Domenech, Antonia, Galian, Laura, Dos, Laura, Casaldaliga, Jaume, Subirana, Mayte, Pedrosa, Valle, Rojas, Mireia et al.
DOI: 10.3109/14767058.2015.1085012

The role of placental alpha microglobulin-1 amnisure in determining the status of the fetal membranes; its association with preterm birth. Traditions ... traditions ....

PMID: 25845275
Journal: Journal of Maternal-Fetal & Neonatal Medicine
Year: 2016
Reference: J Matern Fetal Neonatal Med. 2016 Mar;29(6):1016-20. doi: 10.3109/14767058.2015.1031742. Epub 2015 Sep 25.
Impact factor: 1.674
Publication type: Paper in international publication
Authors: Mariona, Federico G, Roura, Lluis Cabero et al.
DOI: 10.3109/14767058.2015.1031742

Zika fever.

PMID: 26993436
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2016
Reference: Enferm Infecc Microbiol Clin. 2016 Apr;34(4):247-52. doi: 10.1016/j.eimc.2016.02.016. Epub 2016 Mar 15.
Impact factor: 1.53
Publication type: Paper in international publication
Authors: Martinez de Salazar, Pablo, Suy, Anna, Sanchez-Montalva, Adrian, Rodo, Carlota, Salvador, Fernando, Molina, Israel et al.
DOI: 10.1016/j.eimc.2016.02.016

The quantitative lung index and the prediction of survival in fetuses with congenital diaphragmatic hernia.

PMID: 26871273
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2016
Reference: Eur J Obstet Gynecol Reprod Biol. 2016 Mar;198:145-8. doi: 10.1016/j.ejogrb.2016.01.011. Epub 2016 Jan 11.
Impact factor: 1.662
Publication type: Paper in international publication
Authors: Illescas, Tamara, Rodo, Carlota, Arevalo, Silvia, Gine, Carles, Peiro, Jose L, Carreras, Elena et al.
DOI: 10.1016/j.ejogrb.2016.01.011

Cardiac complications during pregnancy are better predicted with the modified WHO risk score.

PMID: 26043149
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2015
Reference: Int J Cardiol. 2015 Sep 15;195:149-54. doi: 10.1016/j.ijcard.2015.05.076. Epub 2015 May 15.
Impact factor: 4.036
Publication type: Paper in international publication
Authors: Pedrosa, V, Pijuan-Domenech, A, Galian, L, Goya, M, Casellas, M, Merced, C, Ferreira-Gonzalez, I, Marsal-Mora, J R, Dos-Subira, L, Subirana-Domenech, M T et al.
DOI: 10.1016/j.ijcard.2015.05.076

Surgery improves survival in elderly with breast cancer. A study of 465 patients in a single institution.

PMID: 25703077
Journal: EJSO
Year: 2015
Reference: Eur J Surg Oncol. 2015 May;41(5):635-40. doi: 10.1016/j.ejso.2015.01.027. Epub 2015 Feb 10.
Impact factor: 3.009
Publication type: Paper in international publication
Authors: Esgueva, A, Rodriguez-Revuelto, R, Espinosa-Bravo, M, Diaz-Botero, S, Xercavins, J, Rubio, I T, Gil-Moreno, A, Alcalde, A, Bernabeu, A, Gascon, A et al.
DOI: 10.1016/j.ejso.2015.01.027

Nidogen 1 and Nuclear Protein 1: novel targets of ETV5 transcription factor involved in endometrial cancer invasion.

PMID: 25924802
Journal: CLINICAL & EXPERIMENTAL METASTASIS
Year: 2015
Reference: Clin Exp Metastasis. 2015 Jun;32(5):467-78. doi: 10.1007/s10585-015-9720-7. Epub 2015 Apr 30.
Impact factor: 3.491
Publication type: Paper in international publication
Authors: Alameda, Francesc, Pedrola, Nuria, Devis, Laura, Llaurado, Marta, Campoy, Irene, Martinez-Garcia, Elena, Garcia, Marta, Muinelo-Romay, Laura, Alonso-Alconada, Lorena, Abal, Miguel et al.
DOI: 10.1007/s10585-015-9720-7

Brain Microdialysis as a Tool To Explore the Ionic Profile of the Brain Extracellular Space in Neurocritical Patients: A Methodological Approach and Feasibility Study.

PMID: 25019674
Journal: JOURNAL OF NEUROTRAUMA
Year: 2015
Reference: J Neurotrauma. 2015 Jan 1;32(1):7-16. doi: 10.1089/neu.2014.3473.
Impact factor: 3.714
Publication type: Paper in international publication
Authors: Martinez-Valverde, Tamara, Vidal-Jorge, Marian, Montoya, Noelia, Sanchez-Guerrero, Angela, Manrique, Susana, Munar, Francisca, Pellegri, Maria-Dolors, Poca, Maria-Antonia, Sahuquillo, Juan et al.
DOI: 10.1089/neu.2014.3473

Inherited antithrombin deficiency and pregnancy: Maternal and fetal outcomes.

PMID: 20047788
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2010
Reference: Eur J Obstet Gynecol Reprod Biol. 2010 Mar;149(1):47-51. Epub 2010 Jan 4.
Impact factor: 1.582
Publication type: Paper in international publication
Authors: , , , , Alijotas Reig, Jaume, et al.
DOI: 10.1016/j.ejogrb.2009.12.004

Blog

News

The team will design and implement a training program for professionals for the respectful care of maternity and childbirth.

Research led by the doctor has stopped unnecessary medicalisation with aspirin during pregnancy.

 

After carrying out a first feasibility trial in collaboration with the Assisted Reproduction Section of the Vall d'Hebron Hospital, Manina Medtech is moving towards a pilot trial in IVF patients.

Job offers

Research Technician-Maternal and Fetal Medicine Research Group
Start date:
21/04/2021
End date:
05/05/2021
Document: Download
Clinical Researcher - Maternal and fetal medicine Research Group
Start date:
17/10/2019
End date:
24/10/2019
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Research technician
Start date:
07/09/2018
End date:
22/09/2018
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