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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Publications

A Spanish case-control study in <5 year-old children reveals the lack of association between MLB and VA astrovirus and diarrhea.

PMID: 32020041
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Feb 4;10(1):1760. doi: 10.1038/s41598-020-58691-3.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Aregall, Nuria, Michl, Kristina, Sabria, Jaume, Rodriguez Garrido, Virginia, Goterris, Lidia, Bosch, Albert, Pinto, Rosa Maria, Guix, Susana, Sabria, Aurora, Vu, Diem-Lan et al.
DOI: 10.1038/s41598-020-58691-3

Rapid and Digital Detection of Inflammatory Biomarkers Enabled by a Novel Portable Nanoplasmonic Imager.

PMID: 31830370
Journal: Small
Year: 2020
Reference: Small. 2020 Jan;16(3):e1906108. doi: 10.1002/smll.201906108. Epub 2019 Dec 12.
Impact factor: 11.459
Publication type: Paper in international publication
Authors: Ferrer, Ricard, Fabrega, Anna, Altug, Hatice, Ruiz-Rodriguez, Juan Carlos, Gonzalez-Lopez, Juan Jose, Yesilkoy, Filiz, Belushkin, Alexander et al.
DOI: 10.1002/smll.201906108

Characterisation of the sewage virome: comparison of NGS tools and occurrence of significant pathogens.

PMID: 31955099
Journal: SCIENCE OF THE TOTAL ENVIRONMENT
Year: 2020
Reference: Sci Total Environ. 2020 Apr 15;713:136604. doi: 10.1016/j.scitotenv.2020.136604. Epub 2020 Jan 8.
Impact factor: 6.551
Publication type: Paper in international publication
Authors: Martinez-Puchol, Sandra, Rusinol, Marta, Fernandez-Cassi, Xavier, Timoneda, Natalia, Itarte, Marta, Andres, Cristina, Anton, Andres, Abril, Josep F, Girones, Rosina, Bofill-Mas, Silvia et al.
DOI: 10.1016/j.scitotenv.2020.136604

Single-locus-sequence-based typing of the mgpB gene reveals transmission dynamics in Mycoplasma genitalium.

PMID: 31941694
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2020
Reference: J Clin Microbiol. 2020 Mar 25;58(4). pii: JCM.01886-19. doi: 10.1128/JCM.01886-19. Print 2020 Mar 25.
Impact factor: 5.897
Publication type: Paper in international publication
Authors: Fernandez-Naval, Candela, Barbera, Maria-Jesus, Aparicio, David, Pich, Oscar Q, Pumarola, Tomas, Jensen, Jorgen S, Espasa, Mateu, Moreno-Mingorance, Albert, Esperalba, Juliana, Serra-Pladevall, Judit et al.
DOI: 10.1128/JCM.01886-19

Approach to amoebic colitis: Epidemiological, clinical and diagnostic considerations in a non-endemic context (Barcelona, 2007-2017).

PMID: 30789955
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Feb 21;14(2):e0212791. doi: 10.1371/journal.pone.0212791. eCollection 2019.
Impact factor: 2.776
Publication type: Paper in international publication
Authors: Roure, Silvia, Valerio, Lluis, Soldevila, Laura, Salvador, Fernando, Fernandez-Rivas, Gema, Sulleiro, Elena, Manosa, Miriam, Sopena, Nieves, Mate, Jose Luis, Clotet, Bonaventura et al.
DOI: 10.1371/journal.pone.0212791

Complicated pneumococcal pneumonia with pleural effusion or empyema in the 13-valent pneumococcal conjugate vaccine era.

PMID: 30784235
Journal: PEDIATRIC PULMONOLOGY
Year: 2019
Reference: Pediatr Pulmonol. 2019 May;54(5):517-524. doi: 10.1002/ppul.24279. Epub 2019 Feb 19.
Impact factor: 2.801
Publication type: Paper in international publication
Authors: Izquierdo, Conchita, Campins, Magda, de Sevilla, Mariona F, Gonzalez-Peris, Sebastia, Uriona, Sonia, Martinez-Osorio, Johanna, Sole-Ribalta, Anna, Codina, Gemma, Esteva, Cristina, Planes, Ana Maria et al.
DOI: 10.1002/ppul.24279

Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016.

PMID: 30782267
Journal: Eurosurveillance
Year: 2019
Reference: Euro Surveill. 2019 Feb;24(7). doi: 10.2807/1560-7917.ES.2019.24.7.1800089.
Impact factor: 7.421
Publication type: Paper in international publication
Authors: Calvo, Cristina, Anton, Andres, Imaz, Manuel, Aranzamendi, Maitane, Hernandez-Rodriguez, Agueda, Moreno-Docon, Antonio, Rey-Cao, Sonia, Navascues, Ana, Otero, Almudena, Cabrerizo, Maria et al.
DOI: 10.2807/1560-7917.ES.2019.24.7.1800089

Pregnancy outcomes after maternal Zika virus infection in a non-endemic region: prospective cohort study.

PMID: 30771526
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2019
Reference: Clin Microbiol Infect. 2019 May;25(5):633.e5-633.e9. doi: 10.1016/j.cmi.2019.02.008. Epub 2019 Feb 14.
Impact factor: 6.425
Publication type: Paper in international publication
Authors: Garrido, Marta, Frick, Antoinette, Rodrigo, Carlos, Pumarola, Tomas, Carreras, Elena, Mendez, Elida Vazquez, Anton, Andres, Rando, Ariadna, Arevalo, Silvia, Rodo, Carlota et al.
DOI: 10.1016/j.cmi.2019.02.008

Blog

News

The collaboration will focus on several key areas of mutual interest in microbiology in particular antimicrobial resistance and stewardship.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.