Skip to main content

Microbiome Research

The Microbiome Research’s group seeks to investigate the role of the microbiota in health and disease. Its secondary objectives include developing molecular as well as bioinformatics tools to characterize the microbiome structure and function, discovering micro-biomarkers for diagnosis and prognosis, investigating how fecal microbiota transplantation could be used as a therapeutic strategy, and evaluating the impact of diet on the gut microbial ecosystem The Microbiome Lab is a multidisciplinary team, composed of molecular biologists, bioinformaticians, and physicians. The group tackles several clinical fields including inflammatory bowel diseases, diabetes, liver diseases, pre-term birth, and critical illness.

Team

Zaida Soler Luque

Zaida Soler Luque

Predoctoral researcher
Microbiome Research
Read more
Gerard Serrano Gomez

Gerard Serrano Gomez

Research technician
Microbiome Research
Read more
Chaysavanh Manichanh

Chaysavanh Manichanh

Head of group
Microbiome Research
Read more
Leidy Alejandra Gonzalez Molano

Leidy Alejandra Gonzalez Molano

Read more
Luis Fernando Mayorga Ayala

Luis Fernando Mayorga Ayala

Predoctoral researcher
Microbiome Research
Read more
Sara Vega Abellaneda

Sara Vega Abellaneda

Read more
Zaida Soler Luque

Zaida Soler Luque

Predoctoral researcher
Microbiome Research
Read more
Gerard Serrano Gomez

Gerard Serrano Gomez

Research technician
Microbiome Research
Read more
Chaysavanh Manichanh

Chaysavanh Manichanh

Head of group
Microbiome Research
Read more
Leidy Alejandra Gonzalez Molano

Leidy Alejandra Gonzalez Molano

Read more
Luis Fernando Mayorga Ayala

Luis Fernando Mayorga Ayala

Predoctoral researcher
Microbiome Research
Read more
Sara Vega Abellaneda

Sara Vega Abellaneda

Read more

Research lines

The Human Microbiome

The Microbiome Research Group seeks to investigate the role of the microbiota in health and disease. Its secondary objectives include: 1. Role of the microbiota in health and disease 2. Tools to characterize the microbiome structure and function 3. Micro-biomarkers for diagnosis and prognosis 4. Fecal microbiota transplantation as a therapeutic strategy 5. Impact of diet on the gut microbial ecosystem

IP: Chaysavanh Manichanh

Projects

Inflammatory Bowel Disease and Microbiome: Diagnosis and prediction of disease activity from the lab to the patients

IP: Chaysavanh Manichanh
Collaborators: Luis Fernando Mayorga Ayala
Funding agency: Instituto de Salud Carlos III
Funding: 65000
Reference: CM21/00198
Duration: 01/01/2022 - 31/12/2023

Evaluate the effect of diet on the gut microbial community

IP: Chaysavanh Manichanh
Collaborators: Zaida Soler Luque
Funding agency: Instituto de Salud Carlos III
Funding: 119567
Reference: FI21/00262
Duration: 01/01/2022 - 31/12/2025

La Microbiota en la Etiología, el Diagnostico y el Tratamiento de la Enfermedad Inflamatoria Intestinal

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Francesc Casellas Jordá
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00614
Duration: 01/01/2018 - 30/06/2022

Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections (FunHoMic)

IP: Chaysavanh Manichanh
Collaborators: Zixuan Xie
Funding agency: EUROPEAN COMMISSION
Funding: 236504.88
Reference: FUNHOMIC_H2020MSCA-ITN2018
Duration: 01/01/2019 - 31/12/2022

pendent

IP: Chaysavanh Manichanh
Collaborators: Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 101250
Reference: CPII18/00006
Duration: 01/01/2019 - 31/12/2021

La Microbiota en la Etiología, el Diagnostico y el Tratamiento de la Enfermedad Inflamatoria Intestinal

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Francesc Casellas Jordá
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00614
Duration: 01/01/2018 - 30/06/2022

Microbiomarkers for prediction and diagnosis of postoperative Crohn's disease recurrence- MiPreDiP_Chron

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: The Crohn's & Colitis Foundation of America
Funding: 170147.63
Reference: MIPREDIP_CHRON2017
Duration: 01/02/2018 - 30/06/2021

Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections (FunHoMic)

IP: Chaysavanh Manichanh
Collaborators: Zixuan Xie
Funding agency: EUROPEAN COMMISSION
Funding: 236504.88
Reference: FUNHOMIC_H2020MSCA-ITN2018
Duration: 01/01/2019 - 31/12/2022

pendent

IP: Chaysavanh Manichanh
Collaborators: Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 101250
Reference: CPII18/00006
Duration: 01/01/2019 - 31/12/2021

La Microbiota en la Etiología, el Diagnostico y el Tratamiento de la Enfermedad Inflamatoria Intestinal

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Francesc Casellas Jordá
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00614
Duration: 01/01/2018 - 30/06/2022

Microbiomarkers for prediction and diagnosis of postoperative Crohn's disease recurrence- MiPreDiP_Chron

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: The Crohn's & Colitis Foundation of America
Funding: 170147.63
Reference: MIPREDIP_CHRON2017
Duration: 01/02/2018 - 30/06/2021

Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections (FunHoMic)

IP: Chaysavanh Manichanh
Collaborators: Zixuan Xie
Funding agency: EUROPEAN COMMISSION
Funding: 236504.88
Reference: FUNHOMIC_H2020MSCA-ITN2018
Duration: 01/01/2019 - 31/12/2022

Integration of meta-omics data to invedstigate the role of the gut microbiota in inflamatory bowel disorders

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-2015-33
Duration: 01/03/2016 - 28/02/2019

Obtención y validación de un coctel microbiano para controlar la inflamación en enfermedad de Crohn

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 103604.66
Reference: SLT002/16/00367
Duration: 06/04/2017 - 31/12/2019

pendent

IP: Chaysavanh Manichanh
Collaborators: Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 101250
Reference: CPII18/00006
Duration: 01/01/2019 - 31/12/2021

La Microbiota en la Etiología, el Diagnostico y el Tratamiento de la Enfermedad Inflamatoria Intestinal

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Francesc Casellas Jordá
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00614
Duration: 01/01/2018 - 30/06/2022

Integration of meta-omics data to invedstigate the role of the gut microbiota in inflamatory bowel disorders

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-2015-33
Duration: 01/03/2016 - 28/02/2019

Obtención y validación de un coctel microbiano para controlar la inflamación en enfermedad de Crohn

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 103604.66
Reference: SLT002/16/00367
Duration: 06/04/2017 - 31/12/2019

Identificación de un consorcio microbiano requerido para restaurar la disbiosis y la homeostasis intestinal en pacientes con colitis ulcerosa

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Natalia Borruel Sainz, Francisco Guarner Aguilar, Francesc Casellas Jordá, Virginia Robles Alonso, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 254402.5
Reference: PI14/00764
Duration: 01/01/2015 - 30/06/2018

La Microbiota en la Etiología, el Diagnostico y el Tratamiento de la Enfermedad Inflamatoria Intestinal

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Francesc Casellas Jordá
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00614
Duration: 01/01/2018 - 30/06/2022

Characterization of the minimum functional microbial consortium required to restore the dysbiosis and the gut homeostasis in patients with ulcerative colitis

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 145080
Reference: INCOMED - FELLOW 2
Duration: 18/08/2014 - 17/08/2017

Integration of meta-omics data to invedstigate the role of the gut microbiota in inflamatory bowel disorders

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-2015-33
Duration: 01/03/2016 - 28/02/2019

Obtención y validación de un coctel microbiano para controlar la inflamación en enfermedad de Crohn

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 103604.66
Reference: SLT002/16/00367
Duration: 06/04/2017 - 31/12/2019

Reshaping the Gut Microbiota for Health

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP13/00181
Duration: 01/01/2014 - 31/03/2017

Characterization of the minimum functional microbial consortium required to restore the dysbiosis and the gut homeostasis in patients with ulcerative colitis

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 145080
Reference: INCOMED - FELLOW 2
Duration: 18/08/2014 - 17/08/2017

Integration of meta-omics data to invedstigate the role of the gut microbiota in inflamatory bowel disorders

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-2015-33
Duration: 01/03/2016 - 28/02/2019

Reshaping the Gut Microbiota for Health

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP13/00181
Duration: 01/01/2014 - 31/03/2017

Identificación de un consorcio microbiano requerido para restaurar la disbiosis y la homeostasis intestinal en pacientes con colitis ulcerosa

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Natalia Borruel Sainz, Francisco Guarner Aguilar, Francesc Casellas Jordá, Virginia Robles Alonso, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 254402.5
Reference: PI14/00764
Duration: 01/01/2015 - 30/06/2018

Characterization of the minimum functional microbial consortium required to restore the dysbiosis and the gut homeostasis in patients with ulcerative colitis

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 145080
Reference: INCOMED - FELLOW 2
Duration: 18/08/2014 - 17/08/2017

Reshaping the Gut Microbiota for Health

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP13/00181
Duration: 01/01/2014 - 31/03/2017

Identificación de un consorcio microbiano requerido para restaurar la disbiosis y la homeostasis intestinal en pacientes con colitis ulcerosa

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Natalia Borruel Sainz, Francisco Guarner Aguilar, Francesc Casellas Jordá, Virginia Robles Alonso, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 254402.5
Reference: PI14/00764
Duration: 01/01/2015 - 30/06/2018

Characterization of the minimum functional microbial consortium required to restore the dysbiosis and the gut homeostasis in patients with ulcerative colitis

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 145080
Reference: INCOMED - FELLOW 2
Duration: 18/08/2014 - 17/08/2017

Análisis de la microbiota asociada al Síndrome de Intestino Irritable

IP: Chaysavanh Manichanh
Collaborators: Francisco Guarner Aguilar, Ana María Accarino Garaventa, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 191180
Reference: PI10/00902
Duration: 01/01/2011 - 30/06/2014

Reshaping the Gut Microbiota for Health

IP: Chaysavanh Manichanh
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP13/00181
Duration: 01/01/2014 - 31/03/2017

Análisis de la microbiota asociada al Síndrome de Intestino Irritable

IP: Chaysavanh Manichanh
Collaborators: Francisco Guarner Aguilar, Ana María Accarino Garaventa, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 191180
Reference: PI10/00902
Duration: 01/01/2011 - 30/06/2014

Análisis de la microbiota asociada al Síndrome de Intestino Irritable

IP: Chaysavanh Manichanh
Collaborators: Francisco Guarner Aguilar, Ana María Accarino Garaventa, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 191180
Reference: PI10/00902
Duration: 01/01/2011 - 30/06/2014

Análisis de la microbiota asociada al Síndrome de Intestino Irritable

IP: Chaysavanh Manichanh
Collaborators: Francisco Guarner Aguilar, Ana María Accarino Garaventa, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 191180
Reference: PI10/00902
Duration: 01/01/2011 - 30/06/2014

Publications

Colonic bacterial diversity and dysbiosis in active microscopic colitis as compared to chronic diarrhoea and healthy controls: effect of polyethylene glycol after bowel lavage for colonoscopy.

PMID: 35764931
Journal: BMC GASTROENTEROLOGY
Year: 2022
Reference: BMC Gastroenterol. 2022 Jun 28;22(1):320. doi: 10.1186/s12876-022-02392-w.
Impact factor: 3.067
Publication type: Paper in international publication
Authors: Batista, Lissette; Robles, Virginia; Manichanh, Chaysavanh; Ruiz, Laura; Pinsach, Ferran; Guarner, Francisco; Fernandez-Banares, Fernando; Guagnozzi, Danila et al.
DOI: 10.1186/s12876-022-02392-w

Blog

News

La composició de la microbiota intestinal és única, com ho són les nostres empremtes dactilars.

FunHoMic integrates experts in fungal pathogenesis, immunology, microbial ecology and "omics" technologies to train 13 researchers to identify biomarkers related to the risk of infection by fungi such as Candida.

The quantification of the gut microbiota, combined with clinical data, would be useful to facilitate the correct diagnosis of patients and offer them the appropriate treatment for their pathology and also to prevent the appearance of flares.

Job offers

Bioinformatician-Microbioma Lab.
Start date:
01/07/2022
End date:
15/07/2022
Document: Download

We are looking for healthy volunteers for a study on the microbiota and eating habits

We are looking for approximately 1,000 volunteers who will have to answer a very simple questionnaire about their eating habits and provide a stool sample, 3 times over the course of a year.

More information