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Molecular Medical Imaging

The Molecular Medical Imaging research group focuses its activity on deepening the molecular bases and developing new areas of research in molecular signaling pathways and the identification of new theranostic targets.

We promote the confluence of basic and clinical researchers, experts in imaging and molecular biology to provide:

  • Access to knowledge of the biokinetics and biodistribution of the molecules under study
  • The proofs of concept necessary in the research processes
  • The identification and quantification of the targets defined by the research groups of our center

In this context, the creation of a translational imaging unit constitutes a basic objective for the development of research aimed at the personalized treatment of patients.

The group is made up of medical specialists in molecular imaging, chemists and pharmacists specializing in tracer synthesis, and biomedical engineers and physicists specializing in image processing and tomography equipment. These are affiliated with different institutions, such as the Vall d'Hebron Research Institute (VHIR), the Vall d'Hebron University Hospital (HUVH) and the Institute of Diagnostic Imaging (IDI).

Publications

The role of PSMA radioligands in the diagnosis and treatment of prostate carcinoma.

PMID: 35216940
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2022
Reference: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2022 Mar-Apr;41(2):126-135. doi: 10.1016/j.remnie.2022.02.001. Epub 2022 Feb 23.
Impact factor: 1.359
Publication type: Paper in international publication
Authors: Rodriguez-Fraile, M, Tamayo Alonso, P, Rosales, J J, de Arcocha-Torres, Maria, Caresia-Aroztegui, A P, Cozar-Santiago, Maria Puig, Orcajo-Rincon, Javier, Simo Perdigo, Marc, Delgado Bolton, R C, Artigas Guix, C et al.
DOI: 10.1016/j.remnie.2022.02.001

Gender differences in outcome in patients with diabetes mellitus.

PMID: 32458331
Journal: JOURNAL OF NUCLEAR CARDIOLOGY
Year: 2022
Reference: J Nucl Cardiol. 2022 Feb;29(1):72-82. doi: 10.1007/s12350-020-02195-0. Epub 2020 May 26.
Impact factor: 5.952
Publication type: Paper in international publication
Authors: Pizzi, Maria Nazarena, Roque, Albert, Candell-Riera, Jaume, Cuellar-Calabria, Hug, Aguade-Bruix, Santiago, Romero-Farina, Guillermo et al.
DOI: 10.1007/s12350-020-02195-0

Phenotyping Type 2 Diabetes in Terms of Myocardial Insulin Resistance and Its Potential Cardiovascular Consequences: A New Strategy Based on (18)F-FDG PET/CT.

PMID: 35055345
Journal: Journal of Personalized Medicine
Year: 2022
Reference: J Pers Med. 2022 Jan 2;12(1). pii: jpm12010030. doi: 10.3390/jpm12010030.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Herance, Jose Raul, Simo, Rafael, Velasquez, Mayra Alejandra, Paun, Bruno, Garcia-Leon, Daniel, Aparicio, Carolina, Mares, Roso, Simo-Servat, Olga, Castell-Conesa, Joan, Hernandez, Cristina et al.
DOI: 10.3390/jpm12010030

The valve uptake index: improving assessment of prosthetic valve endocarditis and updating [18F]FDG PET/CT(A) imaging criteria.

PMID: 34999818
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2022
Reference: Eur Heart J Cardiovasc Imaging. 2022 Jan 6. pii: 6498863. doi: 10.1093/ehjci/jeab279.
Impact factor: 6.875
Publication type: Paper in international publication
Authors: Escobar, Manuel, Roque, Albert, Pizzi, Maria N, Fernandez-Hidalgo, Nuria, Romero-Farina, Guillermo, Burcet, Gemma, Reyes-Juarez, Jose Luis, Espinet, Carina, Castell-Conesa, Joan, Cuellar-Calabria, Hug et al.
DOI: 10.1093/ehjci/jeab279

Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.

PMID: 34830543
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 12;10(22). pii: jcm10225261. doi: 10.3390/jcm10225261.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Valente, Filipa X, Gavara, Jose, Gutierrez, Laura, Rios-Navarro, Cesar, Rello, Pau, Maymi, Manel, Fernandez-Galera, Ruben, Monmeneu, Jose V, Sao-Aviles, Augusto, Lopez-Lereu, Maria P et al.
DOI: 10.3390/jcm10225261

Influenza-Associated Disseminated Aspergillosis in a 9-Year-Old Girl Requiring ECMO Support.

PMID: 34575764
Journal: Journal of Fungi
Year: 2021
Reference: J Fungi (Basel). 2021 Sep 5;7(9). pii: jof7090726. doi: 10.3390/jof7090726.
Impact factor: 5.816
Publication type: Letter or abstract
Authors: Velasco-Nuno, Monica, Mendoza-Palomar, Natalia, Melendo-Perez, Susana, Balcells, Joan, Izquierdo-Blasco, Jaume, Martin-Gomez, Maria Teresa, Soler-Palacin, Pere, Riviere, Jacques G et al.
DOI: 10.3390/jof7090726

Recurrent superinfection in a patient with transjugular intrahepatic portosystemic shunt (endotipsitis), findings on (18)F-FDG PET/CT.

PMID: 34425974
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2021 Sep-Oct;40(5):320-321. doi: 10.1016/j.remnie.2021.03.001. Epub 2021 Mar 11.
Impact factor: 1.359
Publication type: Letter or abstract
Authors: Villasboas-Rosciolesi, D, Simo-Perdigo, M, Castell-Conesa, J, Aguade-Bruix, S et al.
DOI: 10.1016/j.remnie.2021.03.001

Long-term intense FDG uptake in a non-infected prosthetic aortic heart valve implanted 18 years ago.

PMID: 34414551
Journal: JOURNAL OF NUCLEAR CARDIOLOGY
Year: 2021
Reference: J Nucl Cardiol. 2021 Aug 19. pii: 10.1007/s12350-021-02764-x. doi: 10.1007/s12350-021-02764-x.
Impact factor: 5.952
Publication type: Letter or abstract
Authors: Roque, Albert, Blanco, Emilia, Aguade-Bruix, Santiago, Fernandez-Hidalgo, Nuria, Cuellar-Calabria, Hug, Pizzi, Maria Nazarena et al.
DOI: 10.1007/s12350-021-02764-x

Methodology of the (18)F-FDG PET/TC cardiac for the diagnosis of prosthetic endocarditis and intracardiac devices.

PMID: 29496402
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2018
Reference: Rev Esp Med Nucl Imagen Mol. 2018 May - Jun;37(3):163-171. doi: 10.1016/j.remn.2018.01.002. Epub 2018 Feb 26.
Impact factor: 1.202
Publication type: Paper in national publication
Authors: Aguade Bruix, S, Roque Perez, A, Cuellar Calabria, H, Pizzi, M N et al.
DOI: 10.1016/j.remn.2018.01.002

Imaging diagnosis of portal hypertension.

PMID: 29472014
Journal: Radiologia
Year: 2018
Reference: Radiologia. 2018 Jul - Aug;60(4):290-300. doi: 10.1016/j.rx.2017.12.010. Epub 2018 Feb 19.
Impact factor: 0
Publication type: Paper in national publication
Authors: Conangla-Planes, M, Serres, X, Persiva, O, Augustin, S et al.
DOI: 10.1016/j.rx.2017.12.010

Ultrasound findings and associated factors to morbidity in Schistosoma haematobium infection in a highly endemic setting.

PMID: 29205689
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2018
Reference: Trop Med Int Health. 2018 Feb;23(2):221-228. doi: 10.1111/tmi.13020. Epub 2017 Dec 20.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Garcia, Cristina Bocanegra, Pintar, Zeferino, Serres, Xavier, Mendioroz, Jacobo, Moreno, Milagros, Gallego, Sara, Lopez, Teresa, Soriano-Arandes, Antoni, Aznar, Maria Luisa, Sikaleta, Nicolau et al.
DOI: 10.1111/tmi.13020

Clinic-Based Validation of Cerebrospinal Fluid Biomarkers with Florbetapir PET for Diagnosis of Dementia.

PMID: 29154286
Journal: JOURNAL OF ALZHEIMERS DISEASE
Year: 2018
Reference: J Alzheimers Dis. 2018;61(1):135-143. doi: 10.3233/JAD-170753.
Impact factor: 3.476
Publication type: Paper in international publication
Authors: Alvarez, Ignacio, Aguilar, Miquel, Gonzalez, Jose Manuel, Ysamat, Montse, Lorenzo-Bosquet, Carles, Alonso, Alvaro, Tartari, Juan Pablo, Romero, Silvia, Diez-Fairen, Monica, Carcel, Maria et al.
DOI: 10.3233/JAD-170753

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The device, called Winco USG, is a simulation platform for holistic and integrated training of professionals performing this type of procedure.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.