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Molecular Medical Imaging

The Molecular Medical Imaging research group focuses its activity on deepening the molecular bases and developing new areas of research in molecular signaling pathways and the identification of new theranostic targets.

We promote the confluence of basic and clinical researchers, experts in imaging and molecular biology to provide:

  • Access to knowledge of the biokinetics and biodistribution of the molecules under study
  • The proofs of concept necessary in the research processes
  • The identification and quantification of the targets defined by the research groups of our center

In this context, the creation of a translational imaging unit constitutes a basic objective for the development of research aimed at the personalized treatment of patients.

The group is made up of medical specialists in molecular imaging, chemists and pharmacists specializing in tracer synthesis, and biomedical engineers and physicists specializing in image processing and tomography equipment. These are affiliated with different institutions, such as the Vall d'Hebron Research Institute (VHIR), the Vall d'Hebron University Hospital (HUVH) and the Institute of Diagnostic Imaging (IDI).

Team

Eva Mª Lopez Clemente

Eva Mª Lopez Clemente

Research technician
Molecular Medical Imaging
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Felipe Hernando Bartolome

Felipe Hernando Bartolome

Molecular Medical Imaging
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Fiorella Dellepiane Clarke

Fiorella Dellepiane Clarke

Postdoctoral researcher
Molecular Medical Imaging
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Gemma Cuberas Borros

Gemma Cuberas Borros

Research technician
Molecular Medical Imaging
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Hector García  Fernandez

Hector García Fernandez

Research technician
Molecular Medical Imaging
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Hug Cuellar Calabria

Hug Cuellar Calabria

Senior researcher
Molecular Medical Imaging
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Eva Mª Lopez Clemente

Eva Mª Lopez Clemente

Research technician
Molecular Medical Imaging
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Felipe Hernando Bartolome

Felipe Hernando Bartolome

Molecular Medical Imaging
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Fiorella Dellepiane Clarke

Fiorella Dellepiane Clarke

Postdoctoral researcher
Molecular Medical Imaging
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Gemma Cuberas Borros

Gemma Cuberas Borros

Research technician
Molecular Medical Imaging
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Hector García  Fernandez

Hector García Fernandez

Research technician
Molecular Medical Imaging
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Hug Cuellar Calabria

Hug Cuellar Calabria

Senior researcher
Molecular Medical Imaging
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Projects

Insulin resistance in type 2 diabetes: unraveling the pathogenic mechanism between organs

IP: José Raul Herance Camacho
Collaborators: Fiorella Dellepiane Clarke, Joan Castell Conesa, Santiago Aguade Bruix, Carina Espinet Coll, Nuria Roson Gradaille, Carolina Aparicio Gomez, Alberto Roque Pérez, Mònica Velasco Nuño, Julia Baguña Torres, Irene Hernández Hernández, Maria Nazarena Pizzi
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI20/01588
Duration: 01/01/2021 - 30/06/2025

The Vall d’Hebron Iniciative for Parkinson associated to GBA (VHIP-GBA): from biospecimen collection to translational studies and therapies.

IP: Marta Martínez Vicente
Collaborators: José Antonio Arranz Amo, Jorge Hernández Vara, Eddie Pradas Gracia, Guillem Pintos Morell, Clara Carnicer Cáceres, Carles Lorenzo Bosquet, David Moreno Martinez, Jordi Riera Heredia, Marta Montpeyó Garcia-Moreno, Daniela Samaniego Toro, Laura Castillo Ribelles
Funding agency: Instituto de Salud Carlos III
Funding: 245932.5
Reference: PI20/00728
Duration: 01/01/2021 - 30/06/2025

Role of sarcopenia in the evolution of morbidly obese patients who undergo bariatric surgery. Study of cohorts and mechanisms involved.

IP: Andreea Ciudin Mihai
Collaborators: Oscar González López, Fiorella Ximena Palmas Candia, Marina Giralt Arnaiz, Marta Comas Martínez, Rosa Burgos Peláez, Irene Hernández Hernández, Enzamaría Fidilio Meli, Efráin Santiago Cordero Vázquez, Cristina Gamez Cenzano
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI20/01086
Duration: 01/01/2021 - 31/12/2024

Characterization of the CD8 T cell response in Parkinson’s disease for the development of preventive and therapeutic strategies that halt the progression of the disease: SARS-Cov-2-induced long term-hyposmia as a possible prodromal stage

IP: Jordi Bove Badell
Collaborators: Miquel Vila Bover, Alejandro Ferré Masó, Oriol de Fabregues-Boixar Nebot, Carles Lorenzo Bosquet, Thais Cuadros Arasa, Antonio Palasi Franco, David Ramos Vicente, Mariona Marchena Herrera
Funding agency: Instituto de Salud Carlos III
Funding: 165770
Reference: PI21/01358
Duration: 01/01/2022 - 31/12/2024

Publications

The valve uptake index: improving assessment of prosthetic valve endocarditis and updating [18F]FDG PET/CT(A) imaging criteria.

PMID: 34999818
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2022
Reference: Eur Heart J Cardiovasc Imaging. 2022 Jan 6. pii: 6498863. doi: 10.1093/ehjci/jeab279.
Impact factor: 6.875
Publication type: Paper in international publication
Authors: Escobar, Manuel, Roque, Albert, Pizzi, Maria N, Fernandez-Hidalgo, Nuria, Romero-Farina, Guillermo, Burcet, Gemma, Reyes-Juarez, Jose Luis, Espinet, Carina, Castell-Conesa, Joan, Cuellar-Calabria, Hug et al.
DOI: 10.1093/ehjci/jeab279

Corticobasal syndrome: A case of discordance between the clinical findings and the imaging biomarkers.

PMID: 34794916
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2022
Reference: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2022 Jan-Feb;41(1):52-54. doi: 10.1016/j.remnie.2021.05.002. Epub 2021 Nov 16.
Impact factor: 1.359
Publication type: Letter or abstract
Authors: Carrillo-Villamizar, E, Cardozo-Saavedra, A, Lorenzo-Bosquet, C, Lucas Del Pozo, S, Martinez-Saez, E, Hernandez-Vara, J et al.
DOI: 10.1016/j.remnie.2021.05.002

Response to Treatment in IgG4-Related Disease Assessed by Quantitative PET/CT Scan.

PMID: 33630792
Journal: CLINICAL NUCLEAR MEDICINE
Year: 2021
Reference: Clin Nucl Med. 2021 Jun 1;46(6):e307-e311. doi: 10.1097/RLU.0000000000003537.
Impact factor: 7.794
Publication type: Paper in international publication
Authors: Orozco-Galvez, Olimpia, Fernandez-Codina, Andreu, Simo-Perdigo, Marc, Pinal-Fernandez, Iago, Martinez-Valle, Fernando et al.
DOI: 10.1097/RLU.0000000000003537

Classification of acute diverticulitis in the left colon with ultrasonography and computed tomography: value of current severity classification schemes.

PMID: 33612278
Journal: Radiologia
Year: 2021
Reference: Radiologia (Engl Ed). 2021 Feb 18. pii: S0033-8338(21)00028-X. doi: 10.1016/j.rx.2020.12.007.
Impact factor: 0
Publication type: Paper in national publication
Authors: Roson Gradaille, N, Narbona Diez, A, Garriga Farriol, M V, Pruna Comella, X, Pedraza Gutierrez, S, Lopez Cano, M, Badia, J M et al.
DOI: 10.1016/j.rx.2020.12.007

Clinical audits in nuclear medicine: wuthering heights.

PMID: 33610494
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol. 2021 Mar-Apr;40(2):69-71. doi: 10.1016/j.remn.2021.01.004. Epub 2021 Feb 18.
Impact factor: 1.359
Publication type: Editorial in national publication
Authors: Garcia-Burillo, A et al.
DOI: 10.1016/j.remn.2021.01.004

Minimizing acquisition-related radiomics variability by image resampling and batch effect correction to allow for large-scale data analysis.

PMID: 32909055
Journal: EUROPEAN RADIOLOGY
Year: 2021
Reference: Eur Radiol. 2021 Mar;31(3):1460-1470. doi: 10.1007/s00330-020-07174-0. Epub 2020 Sep 9.
Impact factor: 5.315
Publication type: Paper in international publication
Authors: Jordi-Ollero, Olivia, Ligero, Marta, Delgado-Munoz, Eric, Leiva, David, Mast, Richard, Suarez, Cristina, Sala-Llonch, Roser, Calvo, Nahum, Escobar, Manuel, Navarro-Martin, Arturo et al.
DOI: 10.1007/s00330-020-07174-0

Longitudinal Neuroimaging Analysis in Mild-Moderate Alzheimer's Disease Patients Treated with Plasma Exchange with 5% Human Albumin.

PMID: 29154283
Journal: JOURNAL OF ALZHEIMERS DISEASE
Year: 2018
Reference: J Alzheimers Dis. 2018;61(1):321-332. doi: 10.3233/JAD-170693.
Impact factor: 3.476
Publication type: Paper in international publication
Authors: Guzman-de-Villoria, Juan A, Cuberas-Borros, Gemma, Roca, Isabel, Boada, Merce, Tarraga, Lluis, Hernandez, Isabel, Buendia, Mar, Rubio, Lourdes, Torres, Gustavo, Bittini, Angel et al.
DOI: 10.3233/JAD-170693

Takayasu's arteritis relapse.

PMID: 28249725
Journal: JOINT BONE SPINE
Year: 2018
Reference: Joint Bone Spine. 2018 Jan;85(1):119. doi: 10.1016/j.jbspin.2017.02.008. Epub 2017 Feb 27.
Impact factor: 3.304
Publication type: Paper in international publication
Authors: Fernandez-Codina, Andreu, Simo, Marc, Solans-Laque, Roser, Martinez-Valle, Fernando et al.
DOI: 10.1016/j.jbspin.2017.02.008

Blog

News

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

Phase IV AI is included in the Horizon Europe programme, lasts 3 years and prioritises data security and privacy compliance.

YSOTOPE, a DeepTech start-up with the mission to improve the use of immunotherapies through medical imaging, became part of the spin-off network of VHIR and successfully closed its first investment round of €150,000 with Biozell Ventures.

Job offers

Postdoctoral position to develop radiopharmaceuticals targeting glioblastoma
Start date:
14/04/2022
End date:
15/05/2022
Document: Download
LABORATORY TECHNICIAN
Start date:
15/03/2022
End date:
30/03/2022
Document: Download
Diagnostic Imaging Clinical Trials Coordinator
Start date:
20/01/2022
End date:
03/02/2022
Document: Download