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Molecular Medical Imaging

The Molecular Medical Imaging research group focuses its activity on deepening the molecular bases and developing new areas of research in molecular signaling pathways and the identification of new theranostic targets.

We promote the confluence of basic and clinical researchers, experts in imaging and molecular biology to provide:

  • Access to knowledge of the biokinetics and biodistribution of the molecules under study
  • The proofs of concept necessary in the research processes
  • The identification and quantification of the targets defined by the research groups of our center

In this context, the creation of a translational imaging unit constitutes a basic objective for the development of research aimed at the personalized treatment of patients.

The group is made up of medical specialists in molecular imaging, chemists and pharmacists specializing in tracer synthesis, and biomedical engineers and physicists specializing in image processing and tomography equipment. These are affiliated with different institutions, such as the Vall d'Hebron Research Institute (VHIR), the Vall d'Hebron University Hospital (HUVH) and the Institute of Diagnostic Imaging (IDI).

Team

Mònica Velasco Nuño

Mònica Velasco Nuño

Molecular Medical Imaging
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Mª Carmen López  Arribas

Mª Carmen López Arribas

Research technician
Molecular Medical Imaging
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Mª Jose Moreno Negreie

Mª Jose Moreno Negreie

Molecular Medical Imaging
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Nuria  Roson  Gradaille

Nuria Roson Gradaille

Research technician
Molecular Medical Imaging
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Nuria Marques Calvo

Nuria Marques Calvo

Research assistant
Molecular Medical Imaging
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Queralt Martin Saladich

Queralt Martin Saladich

Research technician
Molecular Medical Imaging
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Mònica Velasco Nuño

Mònica Velasco Nuño

Molecular Medical Imaging
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Mª Carmen López  Arribas

Mª Carmen López Arribas

Research technician
Molecular Medical Imaging
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Mª Jose Moreno Negreie

Mª Jose Moreno Negreie

Molecular Medical Imaging
Read more
Nuria  Roson  Gradaille

Nuria Roson Gradaille

Research technician
Molecular Medical Imaging
Read more
Nuria Marques Calvo

Nuria Marques Calvo

Research assistant
Molecular Medical Imaging
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Queralt Martin Saladich

Queralt Martin Saladich

Research technician
Molecular Medical Imaging
Read more

Publications

Advanced Diffusion-Weighted MRI for Cancer Microstructure Assessment in Body Imaging, and Its Relationship With Histology.

PMID: 38032021
Journal: JOURNAL OF MAGNETIC RESONANCE IMAGING
Year: 2023
Reference: J Magn Reson Imaging. 2023 Nov 30. doi: 10.1002/jmri.29144.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Balaguer-Montero, Maria; Barba, Pere; Bobillo, Sabela; Bosch, Francesc; Carpio, Cecilia; Fokkinga, Ella; Grussu, Francesco; Hernandez-Tamames, Juan A; Iacoboni, Gloria et al.
DOI: 10.1002/jmri.29144

Experience and results after the implementation of a radiology day unit in a reference hospital.

PMID: 35767122
Journal: Insights into Imaging
Year: 2022
Reference: Insights Imaging. 2022 Jun 29;13(1):109. doi: 10.1186/s13244-022-01251-2.
Impact factor: 5.231
Publication type: Paper in international publication
Authors: Escobar, Manuel; Tomasello, Alejandro; Perez Lafuente, Mercedes; Andreu, Jordi; Grinon, Jesus; Sanchez-Tirado, Cristina; Mast, Richard; Antolin, Andreu; Roson, Nuria et al.
DOI: 10.1186/s13244-022-01251-2

Impact of revascularization guided by functional testing in ischaemic cardiomyopathy.

PMID: 35781510
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2022
Reference: Eur Heart J Cardiovasc Imaging. 2022 Jul 4. pii: 6628344. doi: 10.1093/ehjci/jeac125.
Impact factor: 6.875
Publication type: Paper in international publication
Authors: Barrabes, Jose A; Aguade-Bruix, Santiago; Ferreira-Gonzalez, Ignacio; Ribera, Aida; Pizzi, Maria Nazarena; Herrador, Lorena; Rodenas-Alesina, Eduard; Romero-Farina, Guillermo; Jordan, Pablo; Espinet-Coll, Carina et al.
DOI: 10.1093/ehjci/jeac125

Avoidance behaviour modulates but does not condition phonophobia in migraine.

PMID: 35815637
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Jul 9:3331024221111772. doi: 10.1177/03331024221111772.
Impact factor: 6.295
Publication type: Paper in international publication
Authors: Pozo-Rosich, Patricia, Gallardo, Victor Jose, Caronna, Edoardo, Vila-Ballo, Adria, Marti-Marca, Angela, Cerda-Company, Xim, Ikumi, Nara et al.
DOI: 10.1177/03331024221111772

False Lumen Flow Assessment by Magnetic Resonance Imaging and Long-Term Outcomes in Uncomplicated Aortic Dissection.

PMID: 35710193
Journal: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Year: 2022
Reference: J Am Coll Cardiol. 2022 Jun 21;79(24):2415-2427. doi: 10.1016/j.jacc.2022.04.017.
Impact factor: 24.093
Publication type: Paper in international publication
Authors: Rodriguez-Palomares, Jose, Ferreira, Ignacio, Bellmunt, Sergi, Rodriguez-Lecoq, Rafael, Teixido-Tura, Gisela, Ruiz, Aroa, Sao-Aviles, Augusto, Rudenick, Paula, Cuellar, Hig, Bijnens, Bart et al.
DOI: 10.1016/j.jacc.2022.04.017

Clinical audits in nuclear medicine: wuthering heights.

PMID: 33610494
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol. 2021 Mar-Apr;40(2):69-71. doi: 10.1016/j.remn.2021.01.004. Epub 2021 Feb 18.
Impact factor:
Publication type: Editorial in national publication
Authors: Garcia-Burillo, A et al.
DOI: 10.1016/j.remn.2021.01.004

Metabolic footprint of aging and obesity in red blood cells.

PMID: 33609087
Journal: Aging-US
Year: 2021
Reference: Aging (Albany NY). 2021 Feb 19;13(4):4850-4880. doi: 10.18632/aging.202693. Epub 2021 Feb 19.
Impact factor:
Publication type: Paper in international publication
Authors: Ciudin, Andreea; Domingo-Orti, Ines; Herance, Jose Raul; Hernandez, Cristina; Lamas-Domingo, Ruben; Palomino-Schatzlein, Martina; Pineda-Lucena, Antonio et al.
DOI: 10.18632/aging.202693

Minimizing acquisition-related radiomics variability by image resampling and batch effect correction to allow for large-scale data analysis.

PMID: 32909055
Journal: EUROPEAN RADIOLOGY
Year: 2021
Reference: Eur Radiol. 2021 Mar;31(3):1460-1470. doi: 10.1007/s00330-020-07174-0. Epub 2020 Sep 9.
Impact factor:
Publication type: Paper in international publication
Authors: Bernatowicz, Kinga; Calvo, Nahum; Delgado-Munoz, Eric; Dienstmann, Rodrigo; Escobar, Manuel; Garcia-Ruiz, Alonso; Jordi-Ollero, Olivia; Leiva, David; Ligero, Marta; Mast, Richard et al.
DOI: 10.1007/s00330-020-07174-0

IgG4 related disease.

PMID: 33547020
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol. 2021 Mar-Apr;40(2):107-114. doi: 10.1016/j.remn.2020.12.001. Epub 2021 Feb 3.
Impact factor:
Publication type: Paper in national publication
Authors: Martinez-Valle, F; Simo-Perdigo, M et al.
DOI: 10.1016/j.remn.2020.12.001

Immunization with the Gly(1127)-Cys(1140) amino acid sequence of the LRP1 receptor reduces atherosclerosis in rabbits. Molecular, immunohistochemical and nuclear imaging studies.

PMID: 32194867
Journal: Theranostics
Year: 2020
Reference: Theranostics. 2020 Feb 10;10(7):3263-3280. doi: 10.7150/thno.37305. eCollection 2020.
Impact factor: 8.579
Publication type: Paper in international publication
Authors: Bornachea, Olga, Benitez-Amaro, Aleyda, Vea, Angela, Nasarre, Laura, de Gonzalo-Calvo, David, Escola-Gil, Juan Carlos, Cedo, Lidia, Iborra, Antoni, Martinez-Martinez, Laura, Juarez, Candido et al.
DOI: 10.7150/thno.37305

Technetium-99m-indocyanine green versus technetium-99m-methylene blue for sentinel lymph node biopsy in early-stage endometrial cancer.

PMID: 31992599
Journal: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Year: 2020
Reference: Int J Gynecol Cancer. 2020 Mar;30(3):311-317. doi: 10.1136/ijgc-2019-000923. Epub 2020 Jan 27.
Impact factor: 2.095
Publication type: Paper in international publication
Authors: Cabrera, Silvia, Bebia, Vicente, Franco-Camps, Silvia, Forcada, Cristina, Villasboas-Rosciolesi, Diego, Navales, Ignacio, Perez-Benavente, Assumpcio, Gil-Moreno, Antonio et al.
DOI: 10.1136/ijgc-2019-000923

Mosaic Bioprostheses May Mimic Infective Endocarditis by PET/CTA: Trust the Uptake Pattern to Avoid Misdiagnosis.

PMID: 31954645
Journal: JACC-Cardiovascular Imaging
Year: 2020
Reference: JACC Cardiovasc Imaging. 2020 Oct;13(10):2239-2244. doi: 10.1016/j.jcmg.2019.11.019. Epub 2020 Jan 15.
Impact factor: 12.74
Publication type: Paper in international publication
Authors: Cuellar-Calabria, Hug, Tornos, Pilar, Roque, Albert, Pizzi, Maria N, Fernandez-Hidalgo, Nuria, Gonzalez-Alujas, Maria Teresa, Rios, Remedios, Castell-Conesa, Joan, Escobar, Manuel, Ferreira-Gonzalez, Ignacio et al.
DOI: 10.1016/j.jcmg.2019.11.019

Morpho-metabolic post-surgical patterns of non-infected prosthetic heart valves by [18F]FDG PET/CTA: "normality" is a possible diagnosis.

PMID: 31539031
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2020
Reference: Eur Heart J Cardiovasc Imaging. 2020 Jan 1;21(1):24-33. doi: 10.1093/ehjci/jez222.
Impact factor: 4.841
Publication type: Paper in international publication
Authors: Fernandez-Hidalgo, Nuria, Permanyer, Eduard, Cuellar-Calabria, Hug, Romero-Farina, Guillermo, Rios, Remedios, Almirante, Benito, Castell-Conesa, Joan, Escobar, Manuel, Ferreira-Gonzalez, Ignacio, Tornos, Pilar et al.
DOI: 10.1093/ehjci/jez222

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.

PMID: 30888539
Journal: ACTA DIABETOLOGICA
Year: 2019
Reference: Acta Diabetol. 2019 May;56(5):569-579. doi: 10.1007/s00592-019-01313-w. Epub 2019 Mar 19.
Impact factor: 2.996
Publication type: Paper in international publication
Authors: Palomo-Buitrago, Maria Encarnacion, Sabater-Masdeu, Monica, Moreno-Navarrete, Jose Maria, Caballano-Infantes, Estefania, Arnoriaga-Rodriguez, Maria, Coll, Claudia, Ramio, Lluis, Palomino-Schatzlein, Martina, Gutierrez-Carcedo, Patricia, Perez-Brocal, Vicente et al.
DOI: 10.1007/s00592-019-01313-w

ONE-STEP NUCLEIC ACID AMPLIFICATION FOR INTRAOPERATIVE ANALYSIS OF SENTINEL LYMPH NODE IN PAPILLARY THYROID CARCINOMA.

PMID: 30400049
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2019
Reference: Eur J Endocrinol. 2019 Jan 1;180(1):21-29. doi: 10.1530/EJE-18-0624.
Impact factor: 5.107
Publication type: Paper in international publication
Authors: Fort, Jose M, Pujol-Borrell, Ricardo, Ramon Y Cajal, Santiago, Gonzalez, Oscar, Castell, Joan, Mesa, Jordi, Roca, Isabel, Caubet, Enric, Iglesias Felip, Carmela, Zafon, Carles et al.
DOI: 10.1530/EJE-18-0624

Learning curves in intraoperative ultrasound guided surgery in breast cancer based on complete breast cancer excision and no need for second surgeries.

PMID: 30737056
Journal: EJSO
Year: 2019
Reference: Eur J Surg Oncol. 2019 Apr;45(4):578-583. doi: 10.1016/j.ejso.2019.01.017. Epub 2019 Feb 1.
Impact factor: 3.379
Publication type: Paper in international publication
Authors: Esgueva, Antonio, Rodriguez-Revuelto, Roberto, Espinosa-Bravo, Martin, Salazar, Juan Pablo, Rubio, Isabel T et al.
DOI: 10.1016/j.ejso.2019.01.017

Percutaneous ultrasound guided vacuum-assisted excision of benign breast lesions: A learning curve to assess outcomes.

PMID: 30359092
Journal: BRITISH JOURNAL OF RADIOLOGY
Year: 2019
Reference: Br J Radiol. 2019 Feb;92(1094):20180626. doi: 10.1259/bjr.20180626. Epub 2018 Nov 29.
Impact factor: 1.939
Publication type: Paper in international publication
Authors: Salazar, Juan Pablo, Miranda, Ignacio, de Torres, Juan, Rus, Maria N, Espinosa-Bravo, Martin, Esgueva, Antonio, Salvador, Rafael, Rubio, Isabel T et al.
DOI: 10.1259/bjr.20180626

Left main coronary artery compression by a large pulmonary artery aneurysm in the absence of pulmonary hypertension: a case report.

PMID: 31020181
Journal: European heart journal. Case reports
Year: 2018
Reference: Eur Heart J Case Rep. 2018 Oct 10;2(4):yty105. doi: 10.1093/ehjcr/yty105. eCollection 2018 Dec.
Impact factor: 0
Publication type: Letter or abstract
Authors: Miranda-Barrio, Berta, Garcia-Romero, Elena, Cuellar-Calabria, Hug, Dos-Subira, Laura et al.
DOI: 10.1093/ehjcr/yty105

Experience In The Treatment Of Neuroendocrine Tumors (TNEs) With Somatostatin-Like Peptides (SLP) Labeled With (LU)-L-177 -DOTATATE

PMID: NOPMID020
Journal: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Year: 2018
Reference: Experience In The Treatment Of Neuroendocrine Tumors (TNEs) With Somatostatin-Like Peptides [...]. EUR J NUCL MED MO I 45(S1)757
Impact factor: 7.704
Publication type: Letter or abstract
Authors: Blanco Cano, J. S, García Burillo, Amparo, Capdevila Castillon, Jaume, Villasboas Rosciolesi, D, Dellepiane Clark, F, Casteras Román, Anna, Castell Conesa, Joan et al.
DOI:

18F-FDG-PET/CTA of prosthetic cardiac valves: postsurgical inflammatory patterns and its temporal evolution. Can we question the 3-month limit of the current guidelines?

PMID: NOPMID021
Journal: EUROPEAN HEART JOURNAL
Year: 2018
Reference: 18F-FDG-PET/CTA of prosthetic cardiac valves: postsurgical inflammatory patterns and its temporal evolution [...]. EUR HEART J 39(S1)
Impact factor: 23.425
Publication type: Letter or abstract
Authors: Rios Barrera, Remedios, Ferreira , Nelson, Sambola Ayala, Antonia, Almirante Gragera, Benito, García-Dorado García, David, Castell Conesa, Joan, Escobar Amores, Manuel, Tornos Mas, Pilar, Aguade Bruix, Santiago, Cuellar Calabria, Hug et al.
DOI: 10.1093/eurheartj/ehy566.5249

First assessment of the clinical impact and confirmation of the diagnostic ability of the 18F-FDG-PET/CTA prosthetic valve endocarditis. New data supports initial results

PMID: NOPMID022
Journal: EUROPEAN HEART JOURNAL
Year: 2018
Reference: First assessment of the clinical impact and confirmation of the diagnostic ability of the [...]. EUR HEART J. 39(s1)450
Impact factor: 23.425
Publication type: Letter or abstract
Authors: Sambolla-Ayala, A, Pizzi , Maria Nazarena, Fernández Hidalgo, Nuria, Cuellar Calabria, Hug, González Alujas, Teresa, Ferreira González, Ignacio, Maisterra Santos, Olga, Rios Barrera, Remedios, Tornos Mas, Pilar, Aguade Bruix, Santiago et al.
DOI: 10.1093/eurheartj/ehy565.P2274

Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance.

PMID: 25623219
Journal: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Year: 2015
Reference: J Am Soc Echocardiogr. 2015 Feb;28(2):119-82. doi: 10.1016/j.echo.2014.11.015.
Impact factor: 4.056
Publication type: Paper in international publication
Authors: Zamorano, Jose Luis, Dietz, Harry, Eagle, Kim, Elefteriades, John, Jondeau, Guillaume, Rousseau, Herve, Schepens, Marc, Weinsaft, Jonathan W, Taylor, Allen J, Oh, Jae K et al.
DOI: 10.1016/j.echo.2014.11.015

Poster Session 1: Sunday 3 May 2015, 08:30-18:00Room: Poster Area.

PMID: 25939923
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2015
Reference: Eur Heart J Cardiovasc Imaging. 2015 May;16 Suppl 1:i11-i28. doi: 10.1093/ehjci/jev051.
Impact factor: 4.105
Publication type: Paper in international publication
Authors: Taniguchi, Y, Takahashi, Y, Toba, T, Yamada, S, Yokoi, K, Kobayashi, S, Okajima, S, Shimane, A, Yasaka, Y, Cabrera, L O et al.
DOI: 10.1093/ehjci/jev051

Moderated Poster Session 2: Sunday 3 May 2015, 15:30-16:30Room: Moderated Poster Area.

PMID: 25939932
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2015
Reference: Eur Heart J Cardiovasc Imaging. 2015 May;16 Suppl 1:i8-i10. doi: 10.1093/ehjci/jev048.
Impact factor: 4.105
Publication type: Paper in international publication
Authors: Pinskiy, M, Sharir, T, Roque, A, Fernandez-Hidalgo, N, Cuellar-Calabria, H, Gonzalez-Alujas, M T, Oristrell, G, Rodriguez-Palomares, J, Tornos, P, Aguade-Bruix, S et al.
DOI: 10.1093/ehjci/jev048

Poster Session 3: Tuesday 5 May 2015, 08:30-12:30Room: Poster Area.

PMID: 25939931
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2015
Reference: Eur Heart J Cardiovasc Imaging. 2015 May;16 Suppl 1:i59-i69. doi: 10.1093/ehjci/jev054.
Impact factor: 4.105
Publication type: Paper in international publication
Authors: Munoz-Bellido, J, Ferreira, Mjv, Robalo, M M, Saraiva, T, Cunha, M J, Goncalves, L, Albuquerque, A, Ramos, D, Costa, G, Lima, J et al.
DOI: 10.1093/ehjci/jev054

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The device, called Winco USG, is a simulation platform for holistic and integrated training of professionals performing this type of procedure.

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.