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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Alejandro  Henao  Paez

Alejandro Henao Paez

Physiology and Pathophysiology of the Digestive Tract
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Ariadna Aguilar Cayuelas

Ariadna Aguilar Cayuelas

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Beatriz Lobo Alvarez

Beatriz Lobo Alvarez

Main researcher
Physiology and Pathophysiology of the Digestive Tract
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Blanca Grases Pintó

Blanca Grases Pintó

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Claudia Maria Herrera de Guise

Claudia Maria Herrera de Guise

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Consuelo Cammarota

Consuelo Cammarota

Administration and Management
Physiology and Pathophysiology of the Digestive Tract
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Alejandro  Henao  Paez

Alejandro Henao Paez

Physiology and Pathophysiology of the Digestive Tract
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Ariadna Aguilar Cayuelas

Ariadna Aguilar Cayuelas

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Beatriz Lobo Alvarez

Beatriz Lobo Alvarez

Main researcher
Physiology and Pathophysiology of the Digestive Tract
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Blanca Grases Pintó

Blanca Grases Pintó

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Claudia Maria Herrera de Guise

Claudia Maria Herrera de Guise

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Consuelo Cammarota

Consuelo Cammarota

Administration and Management
Physiology and Pathophysiology of the Digestive Tract
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Publications

Gastrointestinal dysmotility is associated with proton pump inhibitor refractory esophagitis in patients with systemic sclerosis.

PMID: 39250735
Journal: RHEUMATOLOGY
Year: 2024
Reference: Rheumatology (Oxford). 2024 Sep 9:keae481. doi: 10.1093/rheumatology/keae481.
Impact factor:
Publication type: Paper in international publication
Authors: Alcala-Gonzalez, Luis G; Caselles, Claudia Barber; Cayuelas, Ariadna Aguilar; Codina-Clavaguera, Claudia; Del-Castillo, Alfredo Guillen; Garcia, Antonio Marin; Malagelada, Carolina; Serra, Jordi; Simeon-Aznar, Carmen P et al.
DOI: 10.1093/rheumatology/keae481

Worldwide Prevalence and Description of Cyclic Vomiting Syndrome According to the Results of the Rome Foundation Global Epidemiology Study.

PMID: 39319824
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2024
Reference: Am J Gastroenterol. 2024 Sep 25. doi: 10.14309/ajg.0000000000003105.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Aso, Maria C; Bangdiwala, Shrikant I; Bujanda, Luis; D'Amato, Mauro; Flores-Arriaga, Joel; Huang, I-Hsuan; Izagirre, Arantzazu; Lanas, Angel; Lobo, Beatriz et al.
DOI: 10.14309/ajg.0000000000003105

Genetic and Functional Studies of Patients with Thyroid Dyshormonogenesis and Defects in the TSH Receptor (TSHR).

PMID: 39337518
Journal:
Year: 2024
Reference: Int J Mol Sci. 2024 Sep 18;25(18):10032. doi: 10.3390/ijms251810032.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Riera, Cristina; Antolin, Maria; Baz-Redon, Noelia; Camats-Tarruella, Nuria; Campos-Martorell, Ariadna; Clemente, Maria; Fernandez-Cancio, Monica; Garcia-Arumi, Elena; Gonzalez-Llorens, Nuria; Mogas, Eduard et al.
DOI: 10.3390/ijms251810032

Antiphospholipid syndrome autoantibodies induction after treatment with anti-TNF alpha therapy in patients with IBD.

PMID: 39341406
Journal: Gastroenterologia y Hepatologia
Year: 2024
Reference: Gastroenterol Hepatol. 2024 Sep 26:502258. doi: 10.1016/j.gastrohep.2024.502258.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Casellas, Francesc; Cespedes-Martinez, Elena; Herrera-deGuise, Claudia; Lastiri, Ernesto; Mayorga, Luis; Robles-Alonso, Virginia; Serra, Xavier; Solans, Roser et al.
DOI: 10.1016/j.gastrohep.2024.502258

Acute Stress Regulates Sex-Related Molecular Responses in the Human Jejunal Mucosa: Implications for Irritable Bowel Syndrome.

PMID: 36766765
Journal: Cells
Year: 2023
Reference: Cells. 2023 Jan 27;12(3):423. doi: 10.3390/cells12030423.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; de Torres, Ines; Exposito, Elba; Fortea, Marina; Galan, Carmen; Gallart, Milagros; Gonzalez-Castro, Ana M; Guagnozzi, Danila; Hernandez, Laura; Lobo, Beatriz et al.
DOI: 10.3390/cells12030423

Effectiveness and safety of ustekinumab in bio-naive Crohn's disease patients: a multicentre observational retrospective study.

PMID: 36777363
Journal: Therapeutic Advances in Gastroenterology
Year: 2023
Reference: Therap Adv Gastroenterol. 2023 Feb 9;16:17562848231153560. doi: 10.1177/17562848231153560. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Angel, Ponferrada Diaz; Beatriz, Lopez Cauce; Benito, Velayos Jimenez; Claudia, Herrera de Guise; Claudia, Herrera de Guise; Esteban, Fuentes-Valenzuela; Federico, Arguelles-Arias; Francisco, Mesonero Gismero; Lilyan, Kolle Casso; Luigi, Melcarne et al.
DOI: 10.1177/17562848231153560

Medical consultation in ulcerative colitis: Key elements for improvement.

PMID: 36844134
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2023
Reference: World J Gastroenterol. 2023 Feb 14;29(6):917-925. doi: 10.3748/wjg.v29.i6.917.
Impact factor:
Publication type: Review in international publication
Authors: Cabez, Ana; Casellas, Francesc; Fortes, Pilar; Gomez, Susana; Gonzalez-Lama, Yago; Ricart, Elena et al.
DOI: 10.3748/wjg.v29.i6.917

End to End Colonic Content Assessment: ColonMetry Application.

PMID: 36900054
Journal: Diagnostics
Year: 2023
Reference: Diagnostics (Basel). 2023 Feb 28;13(5):910. doi: 10.3390/diagnostics13050910.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Bendezu, Alvaro; Malagelada, Carolina; Monclus, Eva; Navazo, Isabel; Orellana, Bernat et al.
DOI: 10.3390/diagnostics13050910

Colonic bacterial diversity and dysbiosis in active microscopic colitis as compared to chronic diarrhoea and healthy controls: effect of polyethylene glycol after bowel lavage for colonoscopy.

PMID: 35764931
Journal: BMC GASTROENTEROLOGY
Year: 2022
Reference: BMC Gastroenterol. 2022 Jun 28;22(1):320. doi: 10.1186/s12876-022-02392-w.
Impact factor:
Publication type: Paper in international publication
Authors: Batista, Lissette; Fernandez-Banares, Fernando; Guagnozzi, Danila; Guarner, Francisco; Manichanh, Chaysavanh; Pinsach, Ferran; Robles, Virginia; Ruiz, Laura et al.
DOI: 10.1186/s12876-022-02392-w

Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility.

PMID: 35695704
Journal: United European Gastroenterology Journal
Year: 2022
Reference: United European Gastroenterol J. 2022 Jul;10(6):556-584. doi: 10.1002/ueg2.12259. Epub 2022 Jun 13.
Impact factor:
Publication type: Review in international publication
Authors: Akpinar, Hale; Akyuz, Filiz; Barbara, Giovanni; Barberio, Brigida; Barboi, Oana; Bodini, Giorgia; Bor, Serhat; Chiarioni, Giuseppe; Corsetti, Maura; Cremon, Cesare et al.
DOI: 10.1002/ueg2.12259

Efficacy of pre-test questionnaires and PCR on COVID-19 detection prior to motility examinations.

PMID: 35641109
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Oct;34(10):e14413. doi: 10.1111/nmo.14413. Epub 2022 May 31.
Impact factor:
Publication type: Letter or abstract
Authors: Aguilar, Ariadna; Serra, Jordi et al.
DOI: 10.1111/nmo.14413

Eosinophils in the Gastrointestinal Tract: Key Contributors to Neuro-Immune Crosstalk and Potential Implications in Disorders of Brain-Gut Interaction.

PMID: 35626681
Journal: Cells
Year: 2022
Reference: Cells. 2022 May 14;11(10). pii: cells11101644. doi: 10.3390/cells11101644.
Impact factor:
Publication type: Review in international publication
Authors: Albert-Bayo, Merce; Farre, Ricard; Lobo, Beatriz; Martinez, Cristina; Rodino-Janeiro, Bruno K; Salvo-Romero, Eloisa; Santos, Javier; Vicario, Maria et al.
DOI: 10.3390/cells11101644

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis.

PMID: 34399024
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2021
Reference: Neurogastroenterol Motil. 2021 Aug;33(8):e14237. doi: 10.1111/nmo.14237.
Impact factor:
Publication type: Paper in international publication
Authors: Dickman, Ram; Drug, Vasile; Enck, Paul; Mulak, Agata; Schol, Jolien; Serra, Jordi; Tack, Jan; Wauters, Lucas et al.
DOI: 10.1111/nmo.14237

Propagation patterns of jejunal motor activity measured by high-resolution water-perfused manometry.

PMID: 34378830
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2021
Reference: Neurogastroenterol Motil. 2021 Dec;33(12):e14240. doi: 10.1111/nmo.14240. Epub 2021 Aug 11.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Alcala-Gonzalez, Luis Gerardo; Azpiroz, Fernando; Galan, Carmen; Malagelada, Carolina; Nieto, Adoracion et al.
DOI: 10.1111/nmo.14240

Effectiveness of a Telephone-Based Motivational Intervention for Smoking Cessation in Patients With Crohn Disease: A Randomized, Open-Label, Controlled Clinical Trial.

PMID: 34269705
Journal: Gastroenterology Nursing
Year: 2021
Reference: Gastroenterol Nurs. 2021 Nov-Dec 01;44(6):418-425. doi: 10.1097/SGA.0000000000000572.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel Sainz, Natalia; Casellas Jorda, Francesc; Fuentelsaz Gallego, Carmen; Herrera de Guise, Claudia; Ibarz Casas, Arantxa; Navarro Correal, Ester; Robles Alonso, Virginia; Sanchez Garcia, Josep Maria; Vila Morte, Genoveva et al.
DOI: 10.1097/SGA.0000000000000572

The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome.

PMID: 34165249
Journal: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Year: 2021
Reference: J Cell Mol Med. 2021 Aug;25(16):8047-8061. doi: 10.1111/jcmm.16736. Epub 2021 Jun 24.
Impact factor:
Publication type: Paper in international publication
Authors: Andresen, Viola; Beltran, Caroll; Berens, Sabrina; Boeckxstaens, Guy; Bustamante, Mariona; Clarke, Gerard; Cryan, John F; D'Amato, Mauro; Dinan, Timothy G; Engel, Felicitas et al.
DOI: 10.1111/jcmm.16736

Recommendations of the Spanish Association of Neurogastroenterology and Motility (ASENEM) to restart the activity of gastrintestinal motility laboratories after the state of alarm called due to the Covid-19 pandemic.

PMID: 32680731
Journal: Gastroenterologia y Hepatologia
Year: 2020
Reference: Gastroenterol Hepatol. 2020 Oct;43(8):485-496. doi: 10.1016/j.gastrohep.2020.05.011. Epub 2020 Jun 18.
Impact factor:
Publication type: Paper in national publication
Authors: Accarino, Anna; Alcedo, Javier; Barba, Elizabeth; Mas, Pilar; Perez de la Serna, Julio; Serra, Jordi; Suarez, Jose Francisco et al.
DOI: 10.1016/j.gastrohep.2020.05.011

Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 2: Treatment.

PMID: 32600917
Journal: Gastroenterologia y Hepatologia
Year: 2020
Reference: Gastroenterol Hepatol. 2020 Dec;43(10):649-658. doi: 10.1016/j.gastrohep.2020.04.004. Epub 2020 Jun 27.
Impact factor:
Publication type: Paper in national publication
Authors: Barreiro-de Acosta, Manuel; Beltran, Belen; Chaparro, Maria; Espin, Eloy; Ferrer Bradley, Isabel; Gisbert, Javier P; Guarner, Francisco; Gutierrez, Ana; Marin-Jimenez, Ignacio; Nos, Pilar et al.
DOI: 10.1016/j.gastrohep.2020.04.004

European Society for Neurogastroenterology and Motility (ESNM) recommendations for conducting gastrointestinal motility and function testing in the recovery phase of the COVID-19 pandemic.

PMID: 32525249
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2020
Reference: Neurogastroenterol Motil. 2020 Jul;32(7):e13930. doi: 10.1111/nmo.13930.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Alcedo, Salvatore Tolone Javier; Altomare, Annamaria; Azpiroz, Fernando; Baldi, Fabio; Barba, Elisabeth; Barbara, Giovanni; Bellini, Massimo; Bor, Serhat; Carbone, Florencia et al.
DOI: 10.1111/nmo.13930

Transcriptomic identification of TMIGD1 and its relationship with the ileal epithelial cell differentiation in Crohn's disease.

PMID: 32508154
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2020
Reference: Am J Physiol Gastrointest Liver Physiol. 2020 Aug 1;319(2):G109-G120. doi: 10.1152/ajpgi.00027.2020. Epub 2020 Jun 8.
Impact factor:
Publication type: Paper in international publication
Authors: Aterido, Adria; Cabre, Eduard; Domenech, Eugeni; Ferreiro, Miriam; Garcia-Jaraquemada, Arce; Julia, Antonio; Loren, Violeta; Lozano, Juan Jose; Manosa, Miriam; Manye, Josep et al.
DOI: 10.1152/ajpgi.00027.2020

Gut epithelial and vascular barrier abnormalities in patients with chronic intestinal pseudo-obstruction.

PMID: 31144425
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2019
Reference: Neurogastroenterol Motil. 2019 Aug;31(8):e13652. doi: 10.1111/nmo.13652. Epub 2019 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Bianco, Francesca; Bonora, Elena; Boschetti, Elisa; Caio, Giacomo; Clavenzani, Paolo; Cogliandro, Rosanna F; De Giorgio, Roberto; Giancola, Fiorella et al.
DOI: 10.1111/nmo.13652

Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations.

PMID: 31068256
Journal: PANCREATOLOGY
Year: 2019
Reference: Pancreatology. 2019 Jun;19(4):488-499. doi: 10.1016/j.pan.2019.04.003. Epub 2019 Apr 19.
Impact factor:
Publication type: Paper in international publication
Authors: Aparicio, David Joao; Bajor, Judit; Baltatzis, Minas; Batovsky, Marian; Bertilsson, Sara; Bod, Barnabas; Burgueno-Gomez, Beatriz; Capurso, Gabriele; Carvalho, Joana Rita; Ceranowicz, Piotr et al.
DOI: 10.1016/j.pan.2019.04.003

Effect of a Multistrain Probiotic on Cognitive Function and Risk of Falls in Patients With Cirrhosis: A Randomized Trial.

PMID: 31061952
Journal: Hepatology communications
Year: 2019
Reference: Hepatol Commun. 2019 Mar 12;3(5):632-645. doi: 10.1002/hep4.1325. eCollection 2019 May.
Impact factor:
Publication type: Paper in international publication
Authors: Gely, Cristina; Guarner, Carlos; Juarez, Candido; Manichanh, Chaysavanh; Nieto, Juan Camilo; Poca, Maria; Pozuelo, Marta; Roman, Eva; Soriano, German; Vidal, Silvia et al.
DOI: 10.1002/hep4.1325

Granulocyte-monocyte apheresis: an alternative combination therapy after loss of response to anti-TNF agents in ulcerative colitis.

PMID: 30982369
Journal: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Year: 2019
Reference: Scand J Gastroenterol. 2019 Apr;54(4):459-464. doi: 10.1080/00365521.2019.1600715. Epub 2019 Apr 14.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Urko; Arjona, Dolores; Barreiro-de Acosta, Manuel; Beltran, Belen; Cabriada, Jose Luis; Canete, Fiorella; Fores, Ana; Ginard, Daniel; Gutierrez, Ana; Herrera, Claudia et al.
DOI: 10.1080/00365521.2019.1600715

Th1-skewed profile and excessive production of proinflammatory cytokines in a NFKB1-deficient patient with CVID and severe gastrointestinal manifestations.

PMID: 30063981
Journal: CLINICAL IMMUNOLOGY
Year: 2018
Reference: Clin Immunol. 2018 Oct;195:49-58. doi: 10.1016/j.clim.2018.07.015. Epub 2018 Jul 29.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Blasco, Laura; Colobran, Roger; Dieli-Crimi, Romina; Dieli-Crimi, Romina; Fernandez, Antoni Alvarez; Franco-Jarava, Clara; Martin-Nalda, Andrea; Martinez-Gallo, Monica; Molero, Xavier et al.
DOI: 10.1016/j.clim.2018.07.015

Intestinal Barrier Function in Chronic Kidney Disease.

PMID: 30029474
Journal: Toxins
Year: 2018
Reference: Toxins (Basel). 2018 Jul 19;10(7). pii: toxins10070298. doi: 10.3390/toxins10070298.
Impact factor:
Publication type: Review in national publication
Authors: Dejongh, Sander; Evenepoel, Pieter; Farre, Ricard; Meijers, Bjorn; Vicario, Maria et al.
DOI: 10.3390/toxins10070298

Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder.

PMID: 29964041
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1004-1007. doi: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Canellas, Nicolau; Canueto, Daniel; Gibson, Glenn; Guarner, Francisco; Huaman, Jose-Walter; Jansana, Marta; Malagelada, Carolina; Manichanh, Chaysavanh et al.
DOI: 10.1053/j.gastro.2018.06.045

Toll-like receptors-mediated pathways activate inflammatory responses in the esophageal mucosa of adult eosinophilic esophagitis.

PMID: 29691386
Journal: Clinical and Translational Gastroenterology
Year: 2018
Reference: Clin Transl Gastroenterol. 2018 Apr 25;9(4):147. doi: 10.1038/s41424-018-0017-4.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Angel; Arias-Gonzalez, Laura; Bernardo, David; Fortea, Marina; Gonzalez-Castro, Ana M; Lucendo, Alfredo J; Martinez-Fernandez, Pilar; Montalban-Arques, Ana; Mota-Huertas, Teresa; Olalla, Jose M et al.
DOI: 10.1038/s41424-018-0017-4

Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes.

PMID: 28736331
Journal: BEHAVIOURAL BRAIN RESEARCH
Year: 2017
Reference: Behav Brain Res. 2017 Sep 15;334:50-54. doi: 10.1016/j.bbr.2017.07.026. Epub 2017 Jul 20.
Impact factor:
Publication type: Paper in international publication
Authors: Clarke, Gerard; Cryan, John F; Desbonnet, Lieve; Dinan, Timothy G; Moloney, Gerard M; O'Leary, Olivia F; Salvo-Romero, Eloisa; Shanahan, Fergus et al.
DOI: 10.1016/j.bbr.2017.07.026

Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome.

PMID: 28711627
Journal: GASTROENTEROLOGY
Year: 2017
Reference: Gastroenterology. 2017 Oct;153(4):948-960.e3. doi: 10.1053/j.gastro.2017.06.051. Epub 2017 Jul 13.
Impact factor:
Publication type: Paper in international publication
Authors: Bednarska, Olga; Casado-Bedmar, Maite; Keita, Asa V; Mayer, Emeran A; Salvo-Romero, Eloisa; Strom, Magnus; Vicario, Maria; Walter, Susanna A et al.
DOI: 10.1053/j.gastro.2017.06.051

The role of incongruence between the perceived functioning by patients and clinicians in the detection of psychological distress among functional and motor digestive disorders.

PMID: 28712415
Journal: JOURNAL OF PSYCHOSOMATIC RESEARCH
Year: 2017
Reference: J Psychosom Res. 2017 Aug;99:112-119. doi: 10.1016/j.jpsychores.2017.06.005. Epub 2017 Jun 9.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Eiroa-Orosa, Francisco Jose; Malagelada, Carolina; Rodriguez-Urrutia, Amanda et al.
DOI: 10.1016/j.jpsychores.2017.06.005

Correction of Abdominal Distension by Biofeedback-guided Control of Abdomino-thoracic Muscular Activity in a Randomized, Placebo-Controlled Trial.

PMID: 28705783
Journal: Clinical Gastroenterology and Hepatology
Year: 2017
Reference: Clin Gastroenterol Hepatol. 2017 Dec;15(12):1922-1929. doi: 10.1016/j.cgh.2017.06.052. Epub 2017 Jul 11.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Barba, Elizabeth et al.
DOI: 10.1016/j.cgh.2017.06.052

An exploratory study comparing psychological profiles and its congruence with clinical performance among patients with functional or motility digestive disorders.

PMID: 25921480
Journal: Journal of health psychology
Year: 2016
Reference: J Health Psychol. 2016 Nov;21(11):2590-2599. doi: 10.1177/1359105315581069. Epub 2016 Jul 9.
Impact factor:
Publication type: Letter or abstract
Authors: Accarino, Anna; Azpiroz, Fernando; Eiroa-Orosa, Francisco Jose; Parramon, Gemma; Rodriguez-Urrutia, Amanda; Santamarina-Perez, Pilar et al.
DOI: 10.1177/1359105315581069

Dietary Treatment Modulates Mast Cell Phenotype, Density, and Activity in Adult Eosinophilic Esophagitis.

PMID: 25640519
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2016
Reference: Clin Exp Allergy. 2016 Jan;46(1):78-91. doi: 10.1111/cea.12504.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Angel; Fortea, Marina; Gonzalez-Castro, Ana M; Gonzalez-Cervera, Jesus; Lucendo, Alfredo J; Martinez-Fernandez, Pilar; Mota-Huertas, Teresa; Vicario, Maria; Yague-Compadre, Jose Luis et al.
DOI: 10.1111/cea.12504

Iron Deficiency in the Absence of Anemia Impairs the Perception of Health-Related Quality of Life of Patients with Inflammatory Bowel Disease.

PMID: 27057682
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2016
Reference: Inflamm Bowel Dis. 2016 Jun;22(6):1450-5. doi: 10.1097/MIB.0000000000000768.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Casellas, Francesc; Herrera-deGuise, Claudia; Navarro, Ester; Robles, Virginia et al.
DOI: 10.1097/MIB.0000000000000768

Initial experience in sentinel lymph node detection in pancreatic cancer.

PMID: 26670326
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2016
Reference: Rev Esp Med Nucl Imagen Mol. 2016 Sep-Oct;35(5):287-91. doi: 10.1016/j.remn.2015.10.006. Epub 2015 Dec 3.
Impact factor:
Publication type: Paper in national publication
Authors: Abu-Suboh, M; Armengol, J R; Balsells, J; Beisani, M; Blanco, L; Cardenas, R; Castell, J; Charco, R; Dot, J; Olsina, J J et al.
DOI: 10.1016/j.remn.2015.10.006

Increased humoral immunity in the jejunum of diarrhoea-predominant irritable bowel syndrome associated with clinical manifestations.

PMID: 25209656
Journal: GUT
Year: 2015
Reference: Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Carmen; Azpiroz, Fernando; de Torres, Ines; Fortea, Marina; Gonzalez-Castro, Ana M; Guilarte, Mar; Lobo, Beatriz; Martinez, Cristina; Mosquera, Jose L; Pigrau, Marc et al.
DOI: 10.1136/gutjnl-2013-306236

The Intestinal Gas Questionnaire: development of a new instrument for measuring gas-related symptoms and their impact on daily life.

PMID: 25846412
Journal: NEUROGASTROENT MOTIL
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Jun;27(6):885-98. doi: 10.1111/nmo.12565. Epub 2015 Apr 6.
Impact factor:
Publication type: Paper in international publication
Authors: Arbuckle, R; Azpiroz, F; Chassany, O; Duracinsky, M; Guyonnet, D; Marrel, A; Tugaut, B; Whorwell, P J et al.
DOI: 10.1111/nmo.12565

[Prebiotics: concept, properties and beneficial effects].

PMID: 25659062
Journal: NUTR HOSP
Year: 2015
Reference: Nutr Hosp. 2015 Feb 7;31 Suppl 1:99-118. doi: 10.3305/nh.2015.31.sup1.8715.
Impact factor:
Publication type: Paper in national publication
Authors: Alonso, J L; Azpiroz, F; Calvo, M A; Cirici, M; Clemente, A; Corzo, N; Leis, R; Lombo, F; Mateos-Aparicio, I; Plou, F J et al.
DOI: 10.3305/nh.2015.31.sup1.8715

Intestinal gas homeostasis: disposal pathways.

PMID: 25581042
Journal: NEUROGASTROENT MOTIL
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Mar;27(3):363-369. doi: 10.1111/nmo.12498. Epub 2015 Jan 4.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Bendezu, A; Malagelada, J-R; Mego, M et al.
DOI: 10.1111/nmo.12498

Patients' perceptions, attitudes, and experiences about the management of mild-to-moderate ulcerative colitis.

PMID: 24613279
Journal: Journal of Crohns & Colitis
Year: 2014
Reference: J Crohns Colitis. 2014 Sep 1;8(9):1097-107. doi: 10.1016/j.crohns.2014.02.013. Epub 2014 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: Casellas, Francesc; Menendez, Sabino Riestra; Oliver, Noelia Alfaro; Vicens, Daniel Ginard et al.
DOI: 10.1016/j.crohns.2014.02.013

Probiotic and synbiotic safety in infants under two years of age.

PMID: 24463207
Journal: Beneficial Microbes
Year: 2014
Reference: Benef Microbes. 2014 Mar 1;5(1):45-60. doi: 10.3920/BM2013.0046.
Impact factor:
Publication type: Paper in international publication
Authors: Brummer, R J; Claassen, E; Guarner, F; Morelli, L; van den Nieuwboer, M et al.
DOI: 10.3920/BM2013.0046

Effect of a low-flatulogenic diet in patients with flatulence and functional digestive symptoms.

PMID: 24548289
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2014
Reference: Neurogastroenterol Motil. 2014 Jun;26(6):779-85. doi: 10.1111/nmo.12324. Epub 2014 Feb 19.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Guarner, F; Guyonnet, D; Hernandez, C; Malagelada, J-R; Santos, J et al.
DOI: 10.1111/nmo.12324

Nitrergic and purinergic mechanisms evoke inhibitory neuromuscular transmission in the human small intestine.

PMID: 24372768
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2014
Reference: Neurogastroenterol Motil. 2014 Mar;26(3):419-29. doi: 10.1111/nmo.12293. Epub 2013 Dec 25.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; De Giorgio, R; Gallego, D; Jimenez, M; Malagelada, C; Malagelada, J R et al.
DOI: 10.1111/nmo.12293

Impact of orocecal transit time on patient s perception of lactose intolerance.

PMID: 23548006
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Jan;105(1):13-18.
Impact factor:
Publication type: Paper in national publication
Authors: Aparici, A; Casaus, M; Casellas, F; Malagelada, J R; Rodriguez, P et al.
DOI:

Impact of current smoking on the clinical course of microscopic colitis.

PMID: 23552765
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2013
Reference: Inflamm Bowel Dis. 2013 Jun;19(7):1470-6. doi: 10.1097/MIB.0b013e318281f3cc.
Impact factor:
Publication type: Paper in international publication
Authors: Andreu, Montserrat; Beltran, Belen; Calvo, Marta; de Sousa, Monia R; Esteve, Maria; Fernandez-Banares, Fernando; Garcia-Planella, Esther; Gisbert, Javier P; Iglesias, Eva; Lobo, Beatriz et al.
DOI: 10.1097/MIB.0b013e318281f3cc

Implant survival after deep infection of an instrumented spinal fusion.

PMID: 23908430
Journal: JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
Year: 2013
Reference: Bone Joint J. 2013 Aug;95-B(8):1121-6. doi: 10.1302/0301-620X.95B8.30784.
Impact factor:
Publication type: Paper in international publication
Authors: Bago, J; Caceres, E; Nunez-Pereira, S; Pellise, F; Pigrau, C; Rodriguez-Pardo, D; Villanueva, C et al.
DOI: 10.1302/0301-620X.95B8.30784

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier.

PMID: 22637702
Journal: GUT
Year: 2013
Reference: Gut. 2013 Aug;62(8):1160-8. doi: 10.1136/gutjnl-2012-302093. Epub 2012 May 25.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1136/gutjnl-2012-302093

Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability.

PMID: 22625665
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2012
Reference: Neurogastroenterol Motil. 2012 Aug;24(8):740-6, e348-9. doi: 10.1111/j.1365-2982.2012.01928.x. Epub 2012 May 24.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2982.2012.01928.x

Mucosal healing restores normal health and quality of life in patients with inflammatory bowel disease.

PMID: 22517240
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2012
Reference: Eur J Gastroenterol Hepatol. 2012 Jul;24(7):762-9.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1097/MEG.0b013e32835414b2

Accommodation of the abdomen to its content: integrated abdomino-thoracic response.

PMID: 22188369
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2012
Reference: Neurogastroenterol Motil. 2012 Apr;24(4):312-e162. doi: 10.1111/j.1365-2982.2011.01846.x. Epub 2011 Dec 21.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2982.2011.01846.x

Functional gut disorders or disordered gut function? Small bowel dysmotility evidenced by an original technique.

PMID: 22129212
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2012
Reference: Neurogastroenterol Motil. 2012 Mar;24(3):223-8, e104-5. doi: 10.1111/j.1365-2982.2011.01823.x. Epub 2011 Nov 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2982.2011.01823.x

Abdomino-phrenic dyssynergia in patients with abdominal bloating and distension.

PMID: 21540894
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 May;106(5):815-9.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Burri, Emanuel; Cisternas, Daniel; Malagelada, Juan-R; Soldevilla, Alfredo; Villoria, Albert et al.
DOI: 10.1038/ajg.2010.408

Enterotypes of the human gut microbiome.

PMID: 21508958
Journal: NATURE
Year: 2011
Reference: Nature. 2011 May 12;473(7346):174-80. Epub 2011 Apr 20.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/nature09944

Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis.

PMID: 21465486
Journal: JOURNAL OF PATHOLOGY
Year: 2011
Reference: J Pathol. 2011 Aug;224(4):461-72. doi: 10.1002/path.2870. Epub 2011 Apr 4.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1002/path.2870

A novel nonstop mutation in TYMP does not induce nonstop mRNA decay in a MNGIE patient with severe neuropathy.

PMID: 21412940
Journal: HUMAN MUTATION
Year: 2011
Reference: Hum Mutat. 2011 Apr;32(4):E2061-8. doi: 10.1002/humu.21447. Epub 2011 Jan 18.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Andreu, Antoni L; Martii, Ramon; Pinos, Tomas; Pintos-Morell, Guillem; Rodriguez-Palmero, Agusti; Torres-Torronteras, Javier et al.
DOI: 10.1002/humu.21447

Role of microRNA in IBS with increased gut permeability.

PMID: 20551452
Journal: GUT
Year: 2010
Reference: Gut. 2010 Jun;59(6):710-2.
Impact factor:
Publication type: Editorail in international publication
Authors: Martinez, Cristina; Santos, Javier; Vicario, Maria et al.
DOI: 10.1136/gut.2009.203695

Intestinal motility assessment with video capsule endoscopy: automatic annotation of phasic intestinal contractions.

PMID: 19423434
Journal: IEEE TRANSACTIONS ON MEDICAL IMAGING
Year: 2010
Reference: IEEE Trans Med Imaging. 2010 Feb;29(2):246-59. Epub 2009 May 5.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Deiorio, Fosca; Radeva, Petia; Spyridonos, Panagiota; Vilarino, Fernando; Vitria, Jordi et al.
DOI: 10.1109/TMI.2009.2020753

Influence of colectomy on hydrogen excretion in breath.

PMID: 19902224
Journal: INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
Year: 2010
Reference: Int J Colorectal Dis. 2010 Apr;25(4):485-9. Epub 2009 Nov 10.
Impact factor:
Publication type: Paper in international publication
Authors: Aparici, A; Casaus, M; Casellas, Francesc; Guarner, F; Rodriguez, P; Torrejon, A; Vilaseca, J et al.
DOI: 10.1007/s00384-009-0832-x

Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption.

PMID: 20385250
Journal: Clinical Gastroenterology and Hepatology
Year: 2010
Reference: Clin Gastroenterol Hepatol. 2010 Jul;8(7):581-6. Epub 2010 Apr 10.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1016/j.cgh.2010.03.027

[Treatment of pain in chronic pancreatitis]

PMID: 19231684
Journal: Gastroenterol Hepatol
Year: 2009
Reference: Gastroenterol Hepatol. 2009 Feb;32(2):109-15.
Impact factor:
Publication type: Letter or abstract
Authors: Abu-Suboh, Monder; Dot, Joan; Guarner, Luisa; Olsina, Jorge et al.
DOI: 10.1016/j.gastrohep.2008.02.005

Abdominal distention results from caudo-ventral redistribution of contents.

PMID: 19208364
Journal: GASTROENTEROLOGY
Year: 2009
Reference: Gastroenterology. 2009 May;136(5):1544-51.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Malagelada, Juan-R; Perez, Frederic; Quiroga, Sergi et al.
DOI: 10.1053/j.gastro.2009.01.067

Management of painful chronic pancreatitis with single-dose radiotherapy.

PMID: 19190609
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2009
Reference: Am J Gastroenterol. 2009 Feb;104(2):349-55.
Impact factor:
Publication type: Paper in international publication
Authors: Giralt, Jordi; Guarner, Luisa; Malagelada, J-R; Molero, Xavier; Navalpotro, Begona et al.
DOI: 10.1038/ajg.2008.128

Adhesion properties of Lactobacillus casei strains to resected intestinal fragments and components of the extracellular matrix.

PMID: 18974977
Journal: ARCHIVES OF MICROBIOLOGY
Year: 2009
Reference: Arch Microbiol. 2009 Feb;191(2):153-61.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; de Torres, Ines; Guarner, Francisco; Llopis, Marta; Monedero, Vicente; Munoz-Provencio, Diego; Perez-Martinez, Gaspar et al.
DOI: 10.1007/s00203-008-0436-9

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A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.