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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Daniel León González

Daniel León González

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Danila Guagnozzi

Danila Guagnozzi

Physiology and Pathophysiology of the Digestive Tract
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Elba Exposito Fernandez

Elba Exposito Fernandez

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Elizabeth Barba Orozco

Elizabeth Barba Orozco

Physiology and Pathophysiology of the Digestive Tract
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Francesc Casellas Jordá

Francesc Casellas Jordá

Physiology and Pathophysiology of the Digestive Tract
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Gloria Santaliestra Vivaracho

Gloria Santaliestra Vivaracho

Research assistant
Physiology and Pathophysiology of the Digestive Tract
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Daniel León González

Daniel León González

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Danila Guagnozzi

Danila Guagnozzi

Physiology and Pathophysiology of the Digestive Tract
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Elba Exposito Fernandez

Elba Exposito Fernandez

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Elizabeth Barba Orozco

Elizabeth Barba Orozco

Physiology and Pathophysiology of the Digestive Tract
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Francesc Casellas Jordá

Francesc Casellas Jordá

Physiology and Pathophysiology of the Digestive Tract
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Gloria Santaliestra Vivaracho

Gloria Santaliestra Vivaracho

Research assistant
Physiology and Pathophysiology of the Digestive Tract
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Publications

Recurrent symptoms after achalasia treatment: The value of impedance analysis.

PMID: 39466006
Journal: United European Gastroenterology Journal
Year: 2024
Reference: United European Gastroenterol J. 2024 Oct 28. doi: 10.1002/ueg2.12692.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Cayuelas, Ariadna; Alcala-Gonzalez, Luis G; Quiroga, Sergi; Serra, Jordi et al.
DOI: 10.1002/ueg2.12692

Sex-related differences in the presentation, management and response to treatment of eosinophilic esophagitis: Cross sectional analysis of EoE CONNECT registry.

PMID: 39513462
Journal: United European Gastroenterology Journal
Year: 2024
Reference: United European Gastroenterol J. 2024 Nov 8. doi: 10.1002/ueg2.12699.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Garcia, Marta; Amorena, Edurne; Arias, Angel; Barrio, Jesus; Betore, Elena; Bisso-Zein, Juan Khaled; Blas-Jhon, Leonardo; Carrion, Silvia; Casabona-Frances, Sergio; Cobian, Julyssa et al.
DOI: 10.1002/ueg2.12699

Heterozygous Predicted Loss-of-function Variants of TRAF3 in Patients with Common Variable Immunodeficiency.

PMID: 39579173
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2024
Reference: J Clin Immunol. 2024 Nov 23;45(1):47. doi: 10.1007/s10875-024-01833-3.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilo-Cucurull, Aina; Antolin, Maria; Batlle-Maso, Laura; Colobran, Roger; Dieli-Crimi, Romina; Franco-Jarava, Clara; Garcia-Prat, Marina; Martinez-Gallo, Monica; Moushib, Laith; Parra-Martinez, Alba et al.
DOI: 10.1007/s10875-024-01833-3

A Phase II, multicentric, randomized, double-blind, placebo controlled, proof of concept study of efficacy and safety of Rifamycin SV-MMX(R) 600 mg tablets administered three or two times daily to patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

PMID: 39589118
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2024
Reference: Am J Gastroenterol. 2024 Nov 26. doi: 10.14309/ajg.0000000000003236.
Impact factor:
Publication type: Paper in international publication
Authors: Baert, Didier; Balsiger, Lukas Michaja; Basilisco, Guido; Gentili, Alessandra; Gerloni, Mara; Longo, Luigi; Mazzetti, Alessandro; Moro, Luigi; Piessevaux, Hubert; Santos, Javier et al.
DOI: 10.14309/ajg.0000000000003236

Training and competence in Digestive Endoscopy: Position Paper from the Spanish Society for Digestive Diseases (SEPD).

PMID: 36919658
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2023
Reference: Rev Esp Enferm Dig. 2023 Mar 15;115. doi: 10.17235/reed.2023.9568/2023.
Impact factor:
Publication type: Paper in international publication
Authors: Albillos Martinez, Agustin; Bejarano Garcia, Ana; Casado Martin, Marta; Ceballos Santos, Daniel; Fernandez Vazquez, Inmaculada; Gomez Rodriguez, Rafael Angel; Iglesias Garcia, Julio; Malagelada Prats, Carolina; Malagelada Prats, Carolina; Orive Calzada, Aitor et al.
DOI: 10.17235/reed.2023.9568/2023

JAK inhibitors: A new dawn for oral therapies in inflammatory bowel diseases.

PMID: 36936239
Journal: Frontiers in Medicine
Year: 2023
Reference: Front Med (Lausanne). 2023 Mar 2;10:1089099. doi: 10.3389/fmed.2023.1089099. eCollection 2023.
Impact factor:
Publication type: Review in international publication
Authors: Borruel, Natalia; Herrera-deGuise, Claudia; Lastiri, Ernesto; Lastiri, Ernesto; Serra-Ruiz, Xavier et al.
DOI: 10.3389/fmed.2023.1089099

A comparative study of disorders of gut-brain interaction in Western Europe and Asia based on the Rome foundation global epidemiology study.

PMID: 36961016
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2023
Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14566. doi: 10.1111/nmo.14566. Epub 2023 Mar 24.
Impact factor:
Publication type: Paper in international publication
Authors: Andresen, Viola; Bangdiwala, Shrikant I; Benninga, Marc A; Bonaz, Bruno; Choi, Suck Chei; Corazziari, Enrico S; Fang, Xuicai; Fukudo, Shin; Hreinsson, Johann P; Kanazawa, Motoyori et al.
DOI: 10.1111/nmo.14566

Prevalence and description of disorders of gut-brain interaction in Spain according to the results of the Rome Foundation Global Epidemiology Study.

PMID: 37010843
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2023
Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14582. doi: 10.1111/nmo.14582. Epub 2023 Apr 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Aso, Maria C; Bangdiwala, Shrikant I; Bujanda, Luis; Flores-Arriaga, Joel; Izagirre, Arantzazu; Lanas, Angel; Lobo, Beatriz; Palsson, Olafur S; Sanchez-Pla, Alex et al.
DOI: 10.1111/nmo.14582

Editorial: Human Intestinal Permeability, Mucosal Inflammation and Diet.

PMID: 35495959
Journal: Frontiers in Nutrition
Year: 2022
Reference: Front Nutr. 2022 Apr 11;9:894869. doi: 10.3389/fnut.2022.894869. eCollection 2022.
Impact factor:
Publication type: Editorail in international publication
Authors: Barbara, Giovanni; Santos, Javier et al.
DOI: 10.3389/fnut.2022.894869

Human gut metatranscriptome changes induced by a fermented milk product are associated with improved tolerance to a flatulogenic diet.

PMID: 35465165
Journal: Computational and Structural Biotechnology Journal
Year: 2022
Reference: Comput Struct Biotechnol J. 2022 Apr 5;20:1632-1641. doi: 10.1016/j.csbj.2022.04.001. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Le Neve, Boris; Manichanh, Chaysavanh; Oyarzun, Inigo; Pichaud, Matthieu; Roca, Joaquim; Serrano-Gomez, Gerard; Tap, Julien; Veiga, Patrick; Xie, Zixuan et al.
DOI: 10.1016/j.csbj.2022.04.001

Antibiotics, gut microbiota, and irritable bowel syndrome: What are the relations?

PMID: 35431513
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2022
Reference: World J Gastroenterol. 2022 Mar 28;28(12):1204-1219. doi: 10.3748/wjg.v28.i12.1204.
Impact factor:
Publication type: Review in international publication
Authors: Guarner, Francisco; Ivashkin, Vladimir; Mamieva, Zarina; Poluektova, Elena; Shifrin, Oleg; Sobolev, Vasily; Svistushkin, Valery et al.
DOI: 10.3748/wjg.v28.i12.1204

Elevated Serum Triglyceride Levels in Acute Pancreatitis: A Parameter to be Measured and Considered Early.

PMID: 35355100
Journal: WORLD JOURNAL OF SURGERY
Year: 2022
Reference: World J Surg. 2022 Jul;46(7):1758-1767. doi: 10.1007/s00268-022-06533-w. Epub 2022 Mar 30.
Impact factor:
Publication type: Paper in international publication
Authors: Alberti, Piero; Balsells, Joaquim; Blanco, Laia; Charco, Ramon; Dopazo, Cristina; Fernandez, Nair; Gomez-Jurado, Maria Jose; Hidalgo, Nils Jimmy; Mata, Rodrigo; Molero, Xavier et al.
DOI: 10.1007/s00268-022-06533-w

Acquired hepatocerebral degeneration in a metastatic neuroendocrine tumor long-term survivor - an update on neuroendocrine neoplasm's treatment: A case report.

PMID: 34131474
Journal: World journal of hepatology
Year: 2021
Reference: World J Hepatol. 2021 May 27;13(5):611-619. doi: 10.4254/wjh.v13.i5.611.
Impact factor:
Publication type: Letter or abstract
Authors: Auger, Cristina; Blanco, Laia; Capdevila, Jaume; Garcia-Burillo, Amparo; Gomez-Puerto, Diego; Landolfi, Stefania; Merino, Xavier; Mirallas, Oriol; Molero, Xavier; Riveiro-Barciela, Mar et al.
DOI: 10.4254/wjh.v13.i5.611

Proton pump inhibitor therapy reverses endoscopic features of fibrosis in eosinophilic esophagitis.

PMID: 34120859
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2021
Reference: Dig Liver Dis. 2021 Nov;53(11):1479-1485. doi: 10.1016/j.dld.2021.05.025. Epub 2021 Jun 10.
Impact factor:
Publication type: Paper in international publication
Authors: Alcolea-Valero, Carmen; Arias, Angel; Casabona, Sergio; de la Riva, Susana; Ghisa, Matteo; Guagnozzi, Danila; Laserna-Mendieta, Emilio J; Lucendo, Alfredo J; Majano, Pedro; Navarro, Pilar et al.
DOI: 10.1016/j.dld.2021.05.025

The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19.

PMID: 34104210
Journal: Therapeutic Advances in Gastroenterology
Year: 2021
Reference: Therap Adv Gastroenterol. 2021 May 30;14:17562848211016567. doi: 10.1177/17562848211016567. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Castro, Lara; Alvarez-Lopez, Patricia; Anton, Adrian; Augustin, Salvador; Banares, Juan; Barber, Claudia; Barreira-Diaz, Ana; Biagetti, Betina; Campos-Varela, Isabel; Camps-Relats, Laura et al.
DOI: 10.1177/17562848211016567

Sucrosomial Iron Supplementation for the Treatment of Iron Deficiency Anemia in Inflammatory Bowel Disease Patients Refractory to Oral Iron Treatment.

PMID: 34067320
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 May 22;13(6). pii: nu13061770. doi: 10.3390/nu13061770.
Impact factor:
Publication type: Paper in international publication
Authors: Algaba, Alicia; Bastida, Guillermo; Ber Nieto, Yolanda; Bermejo, Fernando; Gomollon, Fernando; Herrera-de Guise, Claudia; Nos, Pilar; Robles, Virginia; Saez-Gonzalez, Esteban; Soares, Jose Manuel et al.
DOI: 10.3390/nu13061770

Sex Differences and Commonalities in the Impact of a Palatable Meal on Thalamic and Insular Connectivity.

PMID: 32492812
Journal: Nutrients
Year: 2020
Reference: Nutrients. 2020 Jun 1;12(6). pii: nu12061627. doi: 10.3390/nu12061627.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Ciccantelli, Barbara; Kilpatrick, Lisa; Livovsky, Dan M; Malagelada, Carolina; Mayer, Emeran A; Pareto, Deborah; Pribic, Teodora et al.
DOI: 10.3390/nu12061627

Endoscopic stenting for gastroduodenal outlet obstruction of a malignant origin, real life experience in a single center.

PMID: 32496109
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2020
Reference: Rev Esp Enferm Dig. 2020 Sep;112(9):712-715. doi: 10.17235/reed.2020.6600/2019.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Suboh Abadia, Monder; Alcala-Gonzalez, Luis; Armengol Bertroli, Jordi; Armengol Miro, Jose Ramon; Benages Curell, Anna; Castillo Cejas, Maria Dolores; Castro-Reyes, Luz Maria; Dot Bach, Joan; Guevara Cubas, Jorge; Jimenez Hernandez, Cesar et al.
DOI: 10.17235/reed.2020.6600/2019

Motor dysfunction of the gut in cystic fibrosis.

PMID: 32475007
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2020
Reference: Neurogastroenterol Motil. 2020 Sep;32(9):e13883. doi: 10.1111/nmo.13883. Epub 2020 May 31.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Bendezu, R-Alvaro; Malagelada, Carolina; Merino, Xavier; Molero, Xavier; Nieto, Adoracion; Segui, Santi; Sihuay, Denisse; Vitria, Jordi et al.
DOI: 10.1111/nmo.13883

Leishmania infantum asymptomatic infection in inflammatory bowel disease patients under anti-TNF therapy.

PMID: 32420499
Journal: Heliyon
Year: 2020
Reference: Heliyon. 2020 May 8;6(5):e03940. doi: 10.1016/j.heliyon.2020.e03940. eCollection 2020 May.
Impact factor:
Publication type: Paper in international publication
Authors: Alcover, M Magdalena; Berenguer, Diana; Borruel, Natalia; Fisa, Roser; Guillen, M Carmen; Herrera-de Guise, Claudia; Molina, Israel; Moure, Zaira; Riera, Cristina; Rodriguez, Veronica et al.
DOI: 10.1016/j.heliyon.2020.e03940

The experience of inflammatory bowel disease patients with healthcare: A survey with the IEXPAC instrument.

PMID: 30946348
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 Apr;98(14):e15044. doi: 10.1097/MD.0000000000015044.
Impact factor:
Publication type: Paper in international publication
Authors: Casellas, Francesc; Cea-Calvo, Luis; Cortes, Xavier; de Toro, Javier; Galindo, Maria J; Garcia-Sepulcre, Mariana F; Julia, Berta; Marin-Jimenez, Ignacio; Navarro-Correal, Ester; Orozco-Beltran, Domingo et al.
DOI: 10.1097/MD.0000000000015044

Biological Response to Meal Ingestion: Gender Differences.

PMID: 30917512
Journal: Nutrients
Year: 2019
Reference: Nutrients. 2019 Mar 26;11(3). pii: nu11030702. doi: 10.3390/nu11030702.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Amigo, Nuria; Azpiroz, Fernando; Borghi, Giulio; Correig, Xavier; Galan, Carmen; Monrroy, Hugo; Nieto, Adoracion; Pribic, Teodora et al.
DOI: 10.3390/nu11030702

Role of Immunofluorescence and Molecular Diagnosis in the Characterization of Primary Ciliary Dyskinesia.

PMID: 30850195
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2019
Reference: Arch Bronconeumol. 2019 Aug;55(8):439-441. doi: 10.1016/j.arbres.2019.01.021. Epub 2019 Mar 5.
Impact factor:
Publication type: Paper in national publication
Authors: Antolin, Maria; Armengot-Carceller, Miguel; Baz-Redon, Noelia; Camats-Tarruella, Nuria; Carrascosa, Antonio; Fernandez-Cancio, Monica; Garrido-Pontnou, Marta; Moreno-Galdo, Antonio; Reula, Ana; Rovira-Amigo, Sandra et al.
DOI: 10.1016/j.arbres.2019.01.021

Sequential Changes in the Mesenteric Lymph Node Microbiome and Immune Response during Cirrhosis Induction in Rats.

PMID: 30801032
Journal: mSystems
Year: 2019
Reference: mSystems. 2019 Feb 19;4(1). pii: mSystems00278-18. doi: 10.1128/mSystems.00278-18. eCollection 2019 Jan-Feb.
Impact factor:
Publication type: Paper in international publication
Authors: Calvo, Miguel; Clark, Allison; Gallardo, Alberto; Guarner, Carlos; Manichanh, Chaysavanh; Perea, Lidia; Pozuelo, Marta; Sanchez, Elisabet; Santiago, Alba; Sarrabayrouse, Guillaume et al.
DOI: 10.1128/mSystems.00278-18

Expert consensus document: Advances in the diagnosis and classification of gastric and intestinal motility disorders.

PMID: 29622808
Journal: Nature Reviews Gastroenterology & Hepatology
Year: 2018
Reference: Nat Rev Gastroenterol Hepatol. 2018 May;15(5):291-308. doi: 10.1038/nrgastro.2018.7. Epub 2018 Apr 6.
Impact factor:
Publication type: Review in national publication
Authors: Bassotti, Gabrio; Camilleri, Michael; Clarke, John; Dinning, Phil; Fox, Mark; Grover, Madhusudan; Hellstrom, Per M; Ke, Meiyun; Keller, Jutta; Layer, Peter et al.
DOI: 10.1038/nrgastro.2018.7

Activation of Eosinophils and Mast Cells in Functional Dyspepsia: an Ultrastructural Evaluation.

PMID: 29599471
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Mar 29;8(1):5383. doi: 10.1038/s41598-018-23620-y.
Impact factor:
Publication type: Paper in international publication
Authors: Boesmans, Werend; Farre, Ricard; Salvo-Romero, Eloisa; Tack, Jan; Vanheel, Hanne; Vanuytsel, Tim; Vicario, Maria et al.
DOI: 10.1038/s41598-018-23620-y

Meal composition influences postprandial sensations independently of valence and gustation.

PMID: 29575437
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterology & Motility. 2018 Aug;30(8):e13337. doi: 10.1111/nmo.13337.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Hernandez, L; Malagelada, C; Monrroy, H; Nieto, A; Pribic, T; Roca, J; Vilaseca, H et al.
DOI: 10.1111/nmo.13337

Restoration of A Healthy Intestinal Microbiota Normalizes Portal Hypertension In A Rat Model of Nonalcoholic Steatohepatitis.

PMID: 29113028
Journal: HEPATOLOGY
Year: 2018
Reference: Hepatology. 2018 Apr;67(4):1485-1498. doi: 10.1002/hep.29646. Epub 2018 Feb 19.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Bravo, Miren; Garcia-Lezana, Teresa; Genesca, Joan; Manichanh, Chaysavanh; Martell, Maria; Raurell, Imma; Salcedo, Maria Teresa; Santiago, Alba; Schoenenberger, Andreu et al.
DOI: 10.1002/hep.29646

Pancreatic cancer heterogeneity and response to Mek inhibition.

PMID: 28581516
Journal: ONCOGENE
Year: 2017
Reference: Oncogene. 2017 Oct 5;36(40):5639-5647. doi: 10.1038/onc.2017.174. Epub 2017 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Suboh, M; Allende, E; Arribas, J; Balsells, J; Bernado Morales, C; Bilal, F; Carreras, M-J; Macarulla, T; Masso-Valles, D; Mohan, V et al.
DOI: 10.1038/onc.2017.174

Bloating and Abdominal Distension: Old Misconceptions and Current Knowledge.

PMID: 28508867
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2017
Reference: Am J Gastroenterol. 2017 Aug;112(8):1221-1231. doi: 10.1038/ajg.2017.129. Epub 2017 May 16.
Impact factor:
Publication type: Review in national publication
Authors: Accarino, Anna; Azpiroz, Fernando; Malagelada, Juan R et al.
DOI: 10.1038/ajg.2017.129

Collagenous colitis: Requirement for high-dose budesonide as maintenance treatment.

PMID: 28457904
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2017
Reference: Dig Liver Dis. 2017 Sep;49(9):973-977. doi: 10.1016/j.dld.2017.03.026. Epub 2017 Apr 10.
Impact factor:
Publication type: Paper in international publication
Authors: Arguedas, Yolanda; Busquets, David; Casanova, Maria Jose; Fernandez-Banares, Fernando; Fernandez-Salazar, Luis; Gisbert, Javier P; Guagnozzi, Danila; Lucendo, Alfredo J; Perez-Aisa, Angeles; Piqueras, Marta et al.
DOI: 10.1016/j.dld.2017.03.026

Small Bowel Motility.

PMID: 28429202
Journal: Current gastroenterology reports
Year: 2017
Reference: Curr Gastroenterol Rep. 2017 Jun;19(6):26. doi: 10.1007/s11894-017-0565-x.
Impact factor:
Publication type: Review in national publication
Authors: Malagelada, Carolina; Malagelada, Juan R et al.
DOI: 10.1007/s11894-017-0565-x

Perception of lactose intolerance impairs health-related quality of life.

PMID: 27188918
Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION
Year: 2016
Reference: Eur J Clin Nutr. 2016 Sep;70(9):1068-72. doi: 10.1038/ejcn.2016.80. Epub 2016 May 18.
Impact factor:
Publication type: Paper in international publication
Authors: Aparici, A; Casellas, F; Perez, M J; Rodriguez, P et al.
DOI: 10.1038/ejcn.2016.80

Cognitive and hedonic responses to meal ingestion correlate with changes in circulating metabolites.

PMID: 27271780
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2016
Reference: Neurogastroenterol Motil. 2016 Dec;28(12):1806-1814. doi: 10.1111/nmo.12879. Epub 2016 Jun 7.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Alonso-Cotoner, C; Azpiroz, F; Barba, I; Campos, E; Gonzalez, A; Malagelada, C; Malagelada, J-R; Mendez, S; Molne, L et al.
DOI: 10.1111/nmo.12879

Impact of endoscopic ultrasonography (EUS) and EUS-guided fine-needle aspiration on the management of pancreatic cystic lesions.

PMID: 27286570
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2016
Reference: Eur J Gastroenterol Hepatol. 2016 Sep;28(9):1094-9. doi: 10.1097/MEG.0000000000000678.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Isis K; Boadas, Jaume; Busquets, Juli; Cordova, Henry; Fernandez-Cruz, Laureano; Fernandez-Esparrach, Gloria; Ferrer, Joana; Gines, Angels; Molero, Xavier; Navarro, Salvador et al.
DOI: 10.1097/MEG.0000000000000678

Patient satisfaction in the management of mild-to-moderate ulcerative colitis: Results of a Delphi study among patients and physicians.

PMID: 27474198
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2016
Reference: Dig Liver Dis. 2016 Oct;48(10):1172-9. doi: 10.1016/j.dld.2016.06.036. Epub 2016 Jul 14.
Impact factor:
Publication type: Paper in international publication
Authors: Casellas, Francesc; Ginard, Daniel; Riestra, Sabino et al.
DOI: 10.1016/j.dld.2016.06.036

Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?

PMID: 25623659
Journal: AM J GASTROENTEROL
Year: 2015
Reference: Am J Gastroenterol. 2015 Feb;110(2):278-87. doi: 10.1038/ajg.2014.427. Epub 2015 Jan 27.
Impact factor:
Publication type: Paper in international publication
Authors: Clarke, Gerard; de Vos, Willem M; Enck, Paul; Golic, Natasa; Hanevik, Kurt; Iraqi, Fuad A; Jalanka, Jonna; Jonkers, Daisy M; Manichanh, Chaysavanh; Penders, John et al.
DOI: 10.1038/ajg.2014.427

Safety of probiotics and synbiotics in children under 18 years of age.

PMID: 25809217
Journal: BENEF MICROBES
Year: 2015
Reference: Benef Microbes. 2015 Oct 15;6(5):615-30. doi: 10.3920/BM2014.0157. Epub 2015 Apr 22.
Impact factor:
Publication type: Paper in international publication
Authors: Brummer, R J; Cabana, M; Claassen, E; Guarner, F; Morelli, L; van den Nieuwboer, M et al.
DOI: 10.3920/BM2014.0157

Accumulative effect of food residues on intestinal gas production.

PMID: 26303858
Journal: NEUROGASTROENT MOTIL
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Nov;27(11):1621-8. doi: 10.1111/nmo.12662. Epub 2015 Aug 25.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Guarner, F; Malagelada, J-R; Mego, M et al.
DOI: 10.1111/nmo.12662

A review of the systematic review process and its applicability for use in evaluating evidence for health claims on probiotic foods in the European Union.

PMID: 25889449
Journal: NUTR J
Year: 2015
Reference: Nutr J. 2015 Feb 8;14:16. doi: 10.1186/s12937-015-0004-5.
Impact factor:
Publication type: Paper in international publication
Authors: Glanville, Julie; Guarner, Francisco; Hill, Colin; King, Sarah; Sanders, Mary Ellen et al.
DOI: 10.1186/s12937-015-0004-5

Gastric sensitivity and reflexes: basic mechanisms underlying clinical problems.

PMID: 24306100
Journal: JOURNAL OF GASTROENTEROLOGY
Year: 2014
Reference: J Gastroenterol. 2014 Feb;49(2):206-18. doi: 10.1007/s00535-013-0917-8. Epub 2013 Dec 4.
Impact factor:
Publication type: Review in international publication
Authors: Azpiroz, Fernando; Feinle-Bisset, Christine; Grundy, David; Tack, Jan et al.
DOI: 10.1007/s00535-013-0917-8

Anal gas evacuation and colonic microbiota in patients with flatulence: effect of diet.

PMID: 23766444
Journal: GUT
Year: 2014
Reference: Gut. 2014 Mar;63(3):401-8. doi: 10.1136/gutjnl-2012-303013. Epub 2013 Jun 13.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Clemente, Jose C; Eck, Anat; Estrella, Sandra; Gonzalez, Antonio; Guarner, Francisco; Guyonnet, Denis; Hernandez, Carlos; Knight, Rob et al.
DOI: 10.1136/gutjnl-2012-303013

Mechanisms of postprandial abdominal bloating and distension in functional dyspepsia.

PMID: 23645627
Journal: GUT
Year: 2014
Reference: Gut. 2014 Mar;63(3):395-400. doi: 10.1136/gutjnl-2013-304574. Epub 2013 May 4.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Barba, Elizabeth; Burri, Emanuel; Cisternas, Daniel; Huaman, Jose Walter; Malagelada, Juan-R; Soldevilla, Alfredo et al.
DOI: 10.1136/gutjnl-2013-304574

Impaired duodenal mucosal integrity and low-grade inflammation in functional dyspepsia.

PMID: 23474421
Journal: GUT
Year: 2014
Reference: Gut. 2014 Feb;63(2):262-71. doi: 10.1136/gutjnl-2012-303857. Epub 2013 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Farre, Ricard; Keita, Asa V; Martinez, Cristina; Pardon, Nicolas; Santos, Javier; Soderholm, Johan D; Tack, Jan; Van Oudenhove, Lukas; Vanheel, Hanne; Vanuytsel, Tim et al.
DOI: 10.1136/gutjnl-2012-303857

[Progress in the knowledge of the intestinal human microbiota].

PMID: 23848071
Journal: Nutricion Hospitalaria
Year: 2013
Reference: Nutr Hosp. 2013 May-Jun;28(3):553-7. doi: 10.3305/nh.2013.28.3.6601.
Impact factor:
Publication type: Paper in national publication
Authors: Guarner, Francisco; Robles-Alonso, Virginia et al.
DOI: 10.3305/nh.2013.28.3.6601

Satisfaction of health care professionals managing patients with inflammatory bowel disease.

PMID: 23138131
Journal: Journal of Crohns & Colitis
Year: 2013
Reference: J Crohns Colitis. 2013 Aug 1;7(7):e249-55. doi: 10.1016/j.crohns.2012.10.003. Epub 2012 Nov 6.
Impact factor:
Publication type: Paper in international publication
Authors: Casellas, Francesc; Ginard, Daniel; Torrejon, Antonio; Vera, Isabel et al.
DOI: 10.1016/j.crohns.2012.10.003

Urethral catheter-related urinary infection in critical patients admitted to the ICU. Descriptive data of the ENVIN-UCI STUDY.

PMID: 22579562
Journal: Medicina Intensiva
Year: 2013
Reference: Med Intensiva. 2013 Mar;37(2):75-82. doi: 10.1016/j.medin.2012.02.013. Epub 2012 May 11.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.medin.2012.02.013

[Recommendations of the Spanish Pancreatic Club on the diagnosis and treatment of chronic pancreatitis: Part 2 (treatment).]

PMID: 23639273
Journal: Gastroenterologia y Hepatologia
Year: 2013
Reference: Gastroenterol Hepatol. 2013 Jun-Jul;36(6):422-36. doi: 10.1016/j.gastrohep.2012.12.003. Epub 2013 Apr 30.
Impact factor:
Publication type: Paper in national publication
Authors: Abad-Gonzalez, Angel; Aparicio, Jose Ramon; Aparisi, Luis; Boadas, Jaume; Boix, Evangelina; de Las Heras, Gonzalo; de-Madaria, Enrique; Dominguez-Munoz, Enrique; Farre, Antonio; Fernandez-Cruz, Laureano et al.
DOI: 10.1016/j.gastrohep.2012.12.003

The Jejunum of Diarrhea-Predominant Irritable Bowel Syndrome Shows Molecular Alterations in the Tight Junction Signaling Pathway That Are Associated With Mucosal Pathobiology and Clinical Manifestations.

PMID: 22415197
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2012
Reference: Am J Gastroenterol. 2012 May;107(5):736-46. doi: 10.1038/ajg.2011.472. Epub 2012 Mar 13.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/ajg.2011.472

Restoration of quality of life of patients with inflammatory bowel disease after one year with antiTNFalpha treatment.

PMID: 22398074
Journal: Journal of Crohns & Colitis
Year: 2012
Reference: J Crohns Colitis. 2012 Oct;6(9):881-6. doi: 10.1016/j.crohns.2012.01.019. Epub 2012 Feb 14.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.crohns.2012.01.019

Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.

PMID: 21641728
Journal: PSYCHONEUROENDOCRINOLOGY
Year: 2012
Reference: Psychoneuroendocrinology. 2012 Jan;37(1):65-77. Epub 2011 Jun 8.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.psyneuen.2011.05.005

Effect upon hospital activity of the application of a continued care model centered on patients with inflammatory bowel disease.

PMID: 22300112
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2012
Reference: Rev Esp Enferm Dig. 2012 Feb;104(1):16-20. doi: 10.4321/s1130-01082012000100004.
Impact factor: 1.548
Publication type: Paper in national publication
Authors: Castells, Isabel, Borruel-Sainz, Natalia, Casellas-Jorda, Francesc, Torrejon-Herrera, Antonio et al.
DOI: 10.4321/s1130-01082012000100004

[The intestinal microbiota and inflammatory bowel disease.]

PMID: 21377761
Journal: Gastroenterologia y Hepatologia
Year: 2011
Reference: Gastroenterol Hepatol. 2011 Mar;34(3):147-54. Epub 2011 Mar 5.
Impact factor:
Publication type: Letter or abstract
Authors: et al.
DOI: 10.1016/j.gastrohep.2010.11.009

Cystic dystrophy of the pancreas in patient with only one previous cyst.

PMID: 21366373
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2011
Reference: Rev Esp Enferm Dig. 2011 Feb;103(2):95-97.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; et al.
DOI:

Clinical validity of detecting K-ras mutations for the diagnosis of exocrine pancreatic cancer: a prospective study in a clinically-relevant spectrum of patients.

PMID: 21298467
Journal: EUROPEAN JOURNAL OF EPIDEMIOLOGY
Year: 2011
Reference: Eur J Epidemiol. 2011 Mar;26(3):229-36. Epub 2011 Feb 6.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1007/s10654-011-9547-8

Evaluation of oesophageal mucosa integrity by the intraluminal impedance technique.

PMID: 21303918
Journal: GUT
Year: 2011
Reference: Gut. 2011 Jul;60(7):885-92. Epub 2011 Feb 8.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1136/gut.2010.233049

Impaired intestinal gas propulsion in manometrically proven dysmotility and in irritable bowel syndrome.

PMID: 20047636
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2010
Reference: Neurogastroenterol Motil. 2010 Apr;22(4):401-6, e91-2. Epub 2009 Dec 28.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Lobo, B; Malagelada, J-R; Santos, J; Serra, J; Villoria, A et al.
DOI: 10.1111/j.1365-2982.2009.01447.x

Not all lactic acid bacteria are probiotics, ...but some are.

PMID: 20230653
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2010
Reference: Br J Nutr. 2010 Apr;103(7):1079-81. Epub 2010 Mar 16.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; et al.
DOI: 10.1017/S0007114510000723

Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis.

PMID: 19528036
Journal: GUT
Year: 2010
Reference: Gut. 2010 Jan;59(1):12-20. Epub .
Impact factor:
Publication type: Paper in international publication
Authors: Abonia, J P; Ahrens, A; Blanchard, C; Collins, M H; Mingler, M K; Putnam, P E; Rothenberg, M E; Santos, J; Stringer, K F; Vicario, M et al.
DOI: 10.1136/gut.2009.178020

A human gut microbial gene catalogue established by metagenomic sequencing.

PMID: 20203603
Journal: NATURE
Year: 2010
Reference: Nature. 2010 Mar 4;464(7285):59-65.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Artiguenave, Francois; Arumugam, Manimozhiyan; Batto, Jean-Michel; Bertalan, Marcelo; Blottiere, Herve; Bork, Peer; Borruel, Natalia; Bruls, Thomas; Brunak, Soren et al.
DOI: 10.1038/nature08821

A closer look at mucosal inflammation in irritable bowel syndrome: sex- and gender-related disparities--quantity, quality, or both?

PMID: 19174802
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2009
Reference: Am J Gastroenterol. 2009 Feb;104(2):401-3.
Impact factor:
Publication type: Editorail in international publication
Authors: Alonso, Carmen; Santos, Javier et al.
DOI: 10.1038/ajg.2008.105

[When ultrasonography shows a solid mass in the pancreatric head of a patient with epigastric pain, jaundice and weight loss, how should suspicion of adenocarcinoma be confirmed and the degree of extension identified?]

PMID: 19174103
Journal: Gastroenterol Hepatol
Year: 2009
Reference: Gastroenterol Hepatol. 2009 Jan;32(1):61-2.
Impact factor:
Publication type: Letter or abstract
Authors: Guarner, Luisa et al.
DOI: 10.1016/j.gastrohep.2008.10.002

Impaired intestinal molecular tightness in the mucosa of irritable bowel syndrome: what are the mediators?

PMID: 19136518
Journal: GUT
Year: 2009
Reference: Gut. 2009 Feb;58(2):161-2.
Impact factor:
Publication type: Editorail in international publication
Authors: Alonso, Carmen; Santos, Javier; Vicario, Maria et al.
DOI: 10.1136/gut.2008.165670

Metabotyping of biofluids reveals stress-based differences in gut permeability in healthy individuals.

PMID: 19736998
Journal: JOURNAL OF PROTEOME RESEARCH
Year: 2009
Reference: J Proteome Res. 2009 Oct;8(10):4799-809.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Carmen; Guilarte, Mar; Kochhar, Sunil; Lobo, Beatriz; Malagelada, Juan Ramon; Martin, Francois-Pierre; Martinez, Cristina; Ramos, Laura; Rezzi, Serge; Santos, Javier et al.
DOI: 10.1021/pr900525w

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News

A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.