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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Jorge Serra Pueyo

Jorge Serra Pueyo

Main researcher
Physiology and Pathophysiology of the Digestive Tract
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Josefa Mª Heredia Montiel

Josefa Mª Heredia Montiel

Administration and Management
Physiology and Pathophysiology of the Digestive Tract
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Lara Aguilera  Castro

Lara Aguilera Castro

Main researcher
Physiology and Pathophysiology of the Digestive Tract
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Marc Pigrau Pastor

Marc Pigrau Pastor

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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María  Puigcerver  Mas

María Puigcerver Mas

Physiology and Pathophysiology of the Digestive Tract
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María Antolín Mate

María Antolín Mate

Physiology and Pathophysiology of the Digestive Tract
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Jorge Serra Pueyo

Jorge Serra Pueyo

Main researcher
Physiology and Pathophysiology of the Digestive Tract
Read more
Josefa Mª Heredia Montiel

Josefa Mª Heredia Montiel

Administration and Management
Physiology and Pathophysiology of the Digestive Tract
Read more
Lara Aguilera  Castro

Lara Aguilera Castro

Main researcher
Physiology and Pathophysiology of the Digestive Tract
Read more
Marc Pigrau Pastor

Marc Pigrau Pastor

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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María  Puigcerver  Mas

María Puigcerver Mas

Physiology and Pathophysiology of the Digestive Tract
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María Antolín Mate

María Antolín Mate

Physiology and Pathophysiology of the Digestive Tract
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Publications

Impact of gastrointestinal symptoms and psychological distress on quality of life in systemic sclerosis: a cross-sectional study.

PMID: 39609018
Journal: BMJ Open
Year: 2024
Reference: BMJ Open. 2024 Nov 27;14(11):e089725. doi: 10.1136/bmjopen-2024-089725.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Ariadna; Alcala-Gonzalez, Luis Gerardo; Barber, Claudia; Codina, Claudia; Guillen-Del-Castillo, Alfredo; Malagelada, Carolina; Marin Garcia, Antonio; Simeon-Aznar, Carmen P et al.
DOI: 10.1136/bmjopen-2024-089725

Evaluation of Perceived Competence and Satisfaction in Neurogastroenterology and Motility Training During the Gastroenterology Fellowship in Spain.

PMID: 39737846
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2024
Reference: Neurogastroenterol Motil. 2024 Dec 31:e14985. doi: 10.1111/nmo.14985.
Impact factor:
Publication type: Paper in international publication
Authors: Alcala-Gonzalez, Luis G; Alcedo, Javier; Santander, Cecilio; Serra, Jordi; Suarez, Jose Francisco et al.
DOI: 10.1111/nmo.14985

Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.

PMID: 39881982
Journal: Frontiers in Microbiology
Year: 2024
Reference: Front Microbiol. 2025 Jan 15;15:1441126. doi: 10.3389/fmicb.2024.1441126. eCollection 2024.
Impact factor:
Publication type: Paper in international publication
Authors: Albert-Bayo, Merce; Alonso-Cotoner, Carmen; Exposito, Elba; Fortea, Marina; Gabaldon, Toni; Gonzalez-Castro, Ana Maria; Guagnozzi, Danila; Khannous-Lleiffe, Olfat; Lobo, Beatriz; Martinez, Cristina et al.
DOI: 10.3389/fmicb.2024.1441126

The role of cognitive reserve and clinical symptoms in the association between genetic liability for educational attainment and functioning in first-episode psychosis: a mediation analysis.

PMID: 38178712
Journal: EUROPEAN PSYCHIATRY
Year: 2024
Reference: Eur Psychiatry. 2024 Jan 5:1-31. doi: 10.1192/j.eurpsy.2023.2480.
Impact factor:
Publication type: Paper in international publication
Authors: Amoretti, Silvia; Berge, Daniel; Bernardo, Miguel; Clougher, Derek; de la Serna, Elena; Fico, Giovanna; Forte, Maria Florencia; G Segura, Alex; Gasso, Patricia; Gonzalez-Pinto, Ana et al.
DOI: 10.1192/j.eurpsy.2023.2480

Face-to-face interviews versus Internet surveys: Comparison of two data collection methods in the Rome foundation global epidemiology study: Implications for population-based research.

PMID: 37018412
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2023
Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14583. doi: 10.1111/nmo.14583. Epub 2023 Apr 5.
Impact factor:
Publication type: Paper in international publication
Authors: Adibi, Payman; Andresen, Viola; Archampong, Timothy; Bangdiwala, Shrikant I; Benninga, Marc A; Bonaz, Bruno; Bor, Serhat; Buyruk, Murat; Choi, Suck Chei; Corazziari, Enrico S et al.
DOI: 10.1111/nmo.14583

Severe and refractory gastrointestinal toxicity due to immune checkpoint inhibitors: clinical experience in a tertiary referral hospital.

PMID: 37170542
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2023
Reference: Rev Esp Enferm Dig. 2023 May 12. doi: 10.17235/reed.2023.9436/2022.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Borruel, Natalia; Casellas, Francesc; Casellas, Francesc; Cespedes Martinez, Elena; Cespedes Martinez, Elena; Herrera-De Guise, Claudia; Herrera-De Guise, Claudia; Mayorga, Luis; Mayorga, Luis et al.
DOI: 10.17235/reed.2023.9436/2022

Conditioning by a Previous Experience Impairs the Rewarding Value of a Comfort Meal.

PMID: 37242129
Journal: Nutrients
Year: 2023
Reference: Nutrients. 2023 May 9;15(10):2247. doi: 10.3390/nu15102247.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Livovsky, Dan M; Nieto, Adoracion et al.
DOI: 10.3390/nu15102247

Anatomical landmarks localization for capsule endoscopy studies.

PMID: 37267757
Journal: COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Year: 2023
Reference: Comput Med Imaging Graph. 2023 May 18;108:102243. doi: 10.1016/j.compmedimag.2023.102243.
Impact factor:
Publication type: Paper in international publication
Authors: Gilabert, Pere; Laiz, Pablo; Malagelada, Carolina; Segui, Santi; Vitria, Jordi; Watson, Angus J M; Wenzek, Hagen et al.
DOI: 10.1016/j.compmedimag.2023.102243

The Brief Esophageal Dysphagia Questionnaire shows better discriminative capacity for clinical and manometric findings than the Eckardt score: Results from a multicenter study.

PMID: 34342075
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Apr;34(4):e14228. doi: 10.1111/nmo.14228. Epub 2021 Aug 2.
Impact factor:
Publication type: Paper in international publication
Authors: Agotegaray, Joaquin; Ardila-Hani, Andres; Bilder, Claudio; Carlson, Dustin A; Cisternas, Daniel; de la Serna, Julio Perez; de Leon, Antonio Ruiz; Ditaranto, Andres; Glasinovic, Esteban; Hani, Albis et al.
DOI: 10.1111/nmo.14228

Effect of colonic distension on small bowel motility measured by jejunal high-resolution manometry.

PMID: 35318777
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Sep;34(9):e14351. doi: 10.1111/nmo.14351. Epub 2022 Mar 22.
Impact factor:
Publication type: Paper in international publication
Authors: Alcala, Luis G; Azpiroz, Fernando; Livovsky, Dan M; Malagelada, Carolina et al.
DOI: 10.1111/nmo.14351

Percutaneous angiographic arterial embolization of a vascular lesion in the colon of a patient on anticoagulant therapy.

PMID: 33248176
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Apr;45(4):282-283. doi: 10.1016/j.gastrohep.2020.11.011. Epub 2020 Nov 25.
Impact factor:
Publication type: Paper in national publication
Authors: Alonso-Cotoner, Carmen; Gonzalez-Junyent, Carla; Serra-Ruiz, Xavier; Tasayco, Stephanie et al.
DOI: 10.1016/j.gastrohep.2020.11.011

Pancreatitis crónica para el clínico. Parte 2: Tratamiento y seguimiento. Documento de posicionamiento interdisciplinar de la Societat Catalana de Digestologia y la Societat Catalana de Pàncrees (versión castellana)

PMID: 34171422
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Apr;45(4):304-314. doi: 10.1016/j.gastrohep.2021.05.016. Epub 2021 Jun 23.
Impact factor:
Publication type: Paper in national publication
Authors: Ayuso, Juan Ramon; Balsells, Joaquim; Boadas, Jaume; Borobia, Francisco Garcia; Busquets, Juli; Casteras, Anna; Concepcion, Mar; Cuatrecasas, Miriam; Esparrach, Gloria Fernandez; Fort, Esther et al.
DOI: 10.1016/j.gastrohep.2021.05.016

Normalization of long-term quality of life in Crohn's disease patients receiving ustekinumab.

PMID: 33213168
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2021
Reference: Rev Esp Enferm Dig. 2021 May;113(5):313-317. doi: 10.17235/reed.2020.6941/2020.
Impact factor:
Publication type: Paper in national publication
Authors: Borruel Sainz, Natalia; Casellas Jorda, Francesc; Herrera de Guise, Claudia; Marques Cami, Miquel; Mayorga Ayala, Luis; Robles Alonso, Virginia et al.
DOI: 10.17235/reed.2020.6941/2020

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives.

PMID: 33232448
Journal: FEMS MICROBIOLOGY REVIEWS
Year: 2021
Reference: FEMS Microbiol Rev. 2021 May 5;45(3). pii: 6000215. doi: 10.1093/femsre/fuaa060.
Impact factor:
Publication type: Review in international publication
Authors: Alaban, Leovigildo-Rey; Bequet, Frederic; Bornes, Stephanie; Bougnoux, Marie-Elisabeth; Brown, Alistair J P; Chakraborty, Sayoni; Cole, Nathaniel; d'Enfert, Christophe; Delavy, Margot; Emritloll, Yoan et al.
DOI: 10.1093/femsre/fuaa060

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis.

PMID: 33939892
Journal: United European Gastroenterology Journal
Year: 2021
Reference: United European Gastroenterol J. 2021 Apr;9(3):287-306. doi: 10.1002/ueg2.12060.
Impact factor:
Publication type: Paper in international publication
Authors: Dickman, Ram; Drug, Vasile; Enck, Paul; Mulak, Agata; Schol, Jolien; Serra, Jordi; Tack, Jan; Wauters, Lucas et al.
DOI: 10.1002/ueg2.12060

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia.

PMID: 33939891
Journal: United European Gastroenterology Journal
Year: 2021
Reference: United European Gastroenterol J. 2021 Apr;9(3):307-331. doi: 10.1002/ueg2.12061.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Barbara, Giovanni; Bor, Serhat; Coffin, Benoit; Corsetti, Maura; De Schepper, Heiko; Dickman, Ram; Drug, Vasile; Dumitrascu, Dan; Enck, Paul et al.
DOI: 10.1002/ueg2.12061

International Consensus Guidelines for Risk Factors in Chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with the International Association of Pancreatology, the American Pancreatic Association, the Japan Pancreas Society, and European Pancreatic Club.

PMID: 32376198
Journal: PANCREATOLOGY
Year: 2020
Reference: Pancreatology. 2020 Jun;20(4):579-585. doi: 10.1016/j.pan.2020.03.014. Epub 2020 Apr 8.
Impact factor:
Publication type: Review in international publication
Authors: de-Madaria, Enrique; Del Chiaro, Marco; Fernandez-Del Castillo, Carlos; Forsmark, Chris E; Gheorghe, Cristian; Hegyi, Peter; Inui, Kazuo; Lerch, Markus M; Masamune, Atsushi; Molero, Xavier et al.
DOI: 10.1016/j.pan.2020.03.014

A scalable approach to T2-MRI colon segmentation.

PMID: 32353758
Journal: MEDICAL IMAGE ANALYSIS
Year: 2020
Reference: Med Image Anal. 2020 Jul;63:101697. doi: 10.1016/j.media.2020.101697. Epub 2020 Apr 13.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Bendezu, Alvaro; Brunet, Pere; Monclus, Eva; Navazo, Isabel; Orellana, Bernat et al.
DOI: 10.1016/j.media.2020.101697

National survey on the experiences of people with celiac disease in Spain. The CELIAC-SPAIN project.

PMID: 32338009
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2020
Reference: Rev Esp Enferm Dig. 2020 May;112(5):343-354. doi: 10.17235/reed.2020.6929/2020.
Impact factor:
Publication type: Paper in international publication
Authors: Arguelles Arias, Federico; Burgos, Rosa; Casellas Jorda, Francesc; van der Hofstadt Rovira, Maria et al.
DOI: 10.17235/reed.2020.6929/2020

Early postoperative endoscopic recurrence in Crohn's disease is characterized by distinct microbiota recolonization.

PMID: 32333762
Journal: Journal of Crohns & Colitis
Year: 2020
Reference: J Crohns Colitis. 2020 Nov 7;14(11):1535-1546. doi: 10.1093/ecco-jcc/jjaa081.
Impact factor:
Publication type: Paper in international publication
Authors: Campos, David; D'Hoore, Andre; De Hertogh, Gert; Ferrante, Marc; Machiels, Kathleen; Manichanh, Chaysavanh; Martinez-De la Torre, Adrian; Pascal Andreu, Victoria; Pozuelo Del Rio, Marta; Sabino, Joao et al.
DOI: 10.1093/ecco-jcc/jjaa081

Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction.

PMID: 30787928
Journal: Frontiers in Immunology
Year: 2019
Reference: Front Immunol. 2019 Feb 6;10:143. doi: 10.3389/fimmu.2019.00143. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Alameddine, Joudy; Altare, Frederic; Bridonneau, Chantal; Godefroy, Emmanuelle; Jotereau, Francine; Papargyris, Loukas; Sarrabayrouse, Guillaume; Sokol, Harry; Tabiasco, Julie; Yazdanbakhsh, Karina et al.
DOI: 10.3389/fimmu.2019.00143

REPLY TO THE LETTER: Prebiotics Versus Low Fodmap Diet: An Interpretative Nightmare.

PMID: 30794765
Journal: GASTROENTEROLOGY
Year: 2019
Reference: Gastroenterology. 2019 Mar;156(4):1223. doi: 10.1053/j.gastro.2019.02.026.
Impact factor:
Publication type: Letter or abstract
Authors: Azpiroz, Fernando; Gibson, Glenn; Guarner, Francisco et al.
DOI: 10.1053/j.gastro.2019.02.026

Multidisciplinary, evidence-based consensus guidelines for human papillomavirus (HPV) vaccination in high-risk populations, Spain, 2016.

PMID: 30782268
Journal: Eurosurveillance
Year: 2019
Reference: Euro Surveill. 2019 Feb;24(7). doi: 10.2807/1560-7917.ES.2019.24.7.1700857.
Impact factor:
Publication type: Review in international publication
Authors: Alemany, Laia; Borruel, Natalia; Campins, Magda; Castellsague, Xavier; Curran, Adrian; Del Pino, Marta; Diaz-de-Heredia, Cristina; Martinez-Gomez, Xavier; Moraga-Llop, Fernando A; Rodrigo-Pendas, Jose Angel et al.
DOI: 10.2807/1560-7917.ES.2019.24.7.1700857

Mucosal RNA and Protein Expression as the next frontier in IBS: abnormal function despite morphologically intact small intestinal Mucosa.

PMID: 30767681
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2019
Reference: Am J Physiol Gastrointest Liver Physiol. 2019 Jun 1;316(6):G701-G719. doi: 10.1152/ajpgi.00186.2018. Epub 2019 Feb 15.
Impact factor:
Publication type: Paper in international publication
Authors: Martinez, Cristina; Pardo-Camacho, Cristina; Rodino-Janeiro, Bruno Kotska; Santos, Javier et al.
DOI: 10.1152/ajpgi.00186.2018

A Review of Microbiota and Irritable Bowel Syndrome: Future in Therapies.

PMID: 29498019
Journal: ADVANCES IN THERAPY
Year: 2018
Reference: Adv Ther. 2018 Mar;35(3):289-310. doi: 10.1007/s12325-018-0673-5. Epub 2018 Mar 1.
Impact factor:
Publication type: Review in international publication
Authors: Alonso-Cotoner, Carmen; Pascua-Garcia, Roberto; Rodino-Janeiro, Bruno K; Santos, Javier; Vicario, Maria et al.
DOI: 10.1007/s12325-018-0673-5

Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.

PMID: 29490942
Journal: CANCER RESEARCH
Year: 2018
Reference: Cancer Res. 2018 May 15;78(10):2624-2637. doi: 10.1158/0008-5472.CAN-17-1882. Epub 2018 Feb 28.
Impact factor:
Publication type: Paper in international publication
Authors: Campbell, Fiona; Castells, Antoni; Dominguez Fraile, Manuel; Fillat, Cristina; Franch-Exposito, Sebastia; Molero, Xavier; Rovira-Rigau, Maria; Samper, Esther; Sangrador, Irene; Vaquero, Eva C et al.
DOI: 10.1158/0008-5472.CAN-17-1882

Managing iron deficiency and iron deficiency anemia in inflammatory bowel disease. The results of the "Gestiona hierro-EII" survey.

PMID: 29465251
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2018
Reference: Rev Esp Enferm Dig. 2018 Mar;110(3):172-178. doi: 10.17235/reed.2018.5354/2017.
Impact factor:
Publication type: Paper in international publication
Authors: Barreiro-de Acosta, Manuel; Casellas Jorda, Francesc; Judez Gutierrez, Javier; Lopez Roman, Javier; Vazquez Moron, Juan Maria; Vera Mendoza, Isabel et al.
DOI: 10.17235/reed.2018.5354/2017

Epithelial immunity: priming defensive responses in the intestinal mucosa.

PMID: 29146676
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2018
Reference: Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G247-G255. doi: 10.1152/ajpgi.00215.2016. Epub 2017 Nov 16.
Impact factor:
Publication type: Paper in international publication
Authors: Gonzalez-Castro, Ana Maria; Pardo-Camacho, Cristina; Pigrau, Marc; Rodino-Janeiro, Bruno Kotska; Vicario, Maria et al.
DOI: 10.1152/ajpgi.00215.2016

Colonic gas homeostasis: Mechanisms of adaptation following HOST-G904 galactooligosaccharide use in humans.

PMID: 28418214
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2017
Reference: Neurogastroenterol Motil. 2017 Sep;29(9). doi: 10.1111/nmo.13080. Epub 2017 Apr 18.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Gibson, G; Guarner, F; Mego, M; Tzortzis, G; Vulevic, J et al.
DOI: 10.1111/nmo.13080

The microbiome in respiratory medicine: current challenges and future perspectives.

PMID: 28404649
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2017
Reference: Eur Respir J. 2017 Apr 12;49(4). pii: 1602086. doi: 10.1183/13993003.02086-2016. Print 2017 Apr.
Impact factor:
Publication type: Review in national publication
Authors: Agusti, Alvar; Bernasconi, Eric; Chalmers, James D; Dorca, Jordi; Faner, Rosa; Huffnagle, Gary B; Manichanh, Chaysavanh; Molyneaux, Philip L; Monso, Eduard; Paredes, Roger et al.
DOI: 10.1183/13993003.02086-2016

A systems approach identifies time-dependent associations of multimorbidities with pancreatic cancer risk.

PMID: 28383714
Journal: ANNALS OF ONCOLOGY
Year: 2017
Reference: Ann Oncol. 2017 Jul 1;28(7):1618-1624. doi: 10.1093/annonc/mdx167.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, J; Barbera, V M; Bosetti, C; Carrato, A; Costello, E; Crnogorac-Jurcevic, T; Dominguez-Munoz, E; Farre, A; Furlong, L I; Gomez-Rubio, P et al.
DOI: 10.1093/annonc/mdx167

Appetite influences the responses to meal ingestion.

PMID: 28370941
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2017
Reference: Neurogastroenterol Motil. 2017 Aug;29(8). doi: 10.1111/nmo.13072. Epub 2017 Mar 31.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Hernandez, L; Malagelada, C; Nieto, A; Pribic, T et al.
DOI: 10.1111/nmo.13072

Impact of endoscopic ultrasonography (EUS) and EUS-guided fine-needle aspiration on the management of pancreatic cystic lesions.

PMID: 27286570
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2016
Reference: Eur J Gastroenterol Hepatol. 2016 Sep;28(9):1094-9. doi: 10.1097/MEG.0000000000000678.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Isis K; Boadas, Jaume; Busquets, Juli; Cordova, Henry; Fernandez-Cruz, Laureano; Fernandez-Esparrach, Gloria; Ferrer, Joana; Gines, Angels; Molero, Xavier; Navarro, Salvador et al.
DOI: 10.1097/MEG.0000000000000678

Colonic content in health and its relation to functional gut symptoms.

PMID: 26871593
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2016
Reference: Neurogastroenterol Motil. 2016 Jun;28(6):849-54. doi: 10.1111/nmo.12782. Epub 2016 Feb 12.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Barba, E; Bendezu, R A; Burri, E; Cisternas, D; Malagelada, J-R; Monclus, E; Navazo, I; Quiroga, S et al.
DOI: 10.1111/nmo.12782

Health-related quality of life and determinant factors in celiac disease. A population-based analysis of adult patients in Spain.

PMID: 26901502
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2016
Reference: Rev Esp Enferm Dig. 2016 Apr;108(4):181-9. doi: 10.17235/reed.2016.4094/2015.
Impact factor:
Publication type: Paper in international publication
Authors: Casellas, Francesc; Hernandez Martinez, Antonio; Lucendo, Alfredo Jose; Rodriguez Almagro, Julian; Siles Gonzalez, Jose; Solano Ruiz, Maria Carmen et al.
DOI: 10.17235/reed.2016.4094/2015

Development and Validation of the Short Crohn's Disease Work Disability Questionnaire.

PMID: 26933747
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2016
Reference: Inflamm Bowel Dis. 2016 Apr;22(4):955-62. doi: 10.1097/MIB.0000000000000678.
Impact factor:
Publication type: Paper in international publication
Authors: Calvet, Xavier; Casellas, Francesc; Gomollon, Fernando; Prieto, Luis; Ramos, Alexis; Sicilia, Beatriz; Vergara, Mercedes et al.
DOI: 10.1097/MIB.0000000000000678

A Single Mutation in the Gene Responsible for the Mucoid Phenotype of Bifidobacterium animalis subsp. lactis Confers Surface and Functional Characteristics.

PMID: 26362981
Journal: APPL ENVIRON MICROB
Year: 2015
Reference: Appl Environ Microbiol. 2015 Dec 1;81(23):7960-8. doi: 10.1128/AEM.02095-15. Epub 2015 Sep 11.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Martin, Pablo; Antolin, Maria; Berger, Bernard; Delley, Michele; Guarner, Francisco; Hidalgo-Cantabrana, Claudio; Lopez, Patricia; Margolles, Abelardo; Marti, Marc; Martinez-Alvarez, Noelia et al.
DOI: 10.1128/AEM.02095-15

[Use of probiotics and prebiotics in primary care].

PMID: 25659055
Journal: NUTR HOSP
Year: 2015
Reference: Nutr Hosp. 2015 Feb 7;31 Suppl 1:59-63. doi: 10.3305/nh.2015.31.sup1.8708.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez Calatayud, Guillermo; Azpiroz, Fernando et al.
DOI: 10.3305/nh.2015.31.sup1.8708

Reduction of butyrate- and methane-producing microorganisms in patients with Irritable Bowel Syndrome.

PMID: 26239401
Journal: SCI REP-UK
Year: 2015
Reference: Sci Rep. 2015 Aug 4;5:12693. doi: 10.1038/srep12693.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Guarner, Francisco; Manichanh, Chaysavanh; Mendez, Sara; Panda, Suchita; Pozuelo, Marta; Santiago, Alba; Santos, Javier et al.
DOI: 10.1038/srep12693

Motility bar: A new tool for motility analysis of endoluminal videos.

PMID: 25912458
Journal: COMPUT BIOL MED
Year: 2015
Reference: Comput Biol Med. 2015 Oct 1;65:320-30. doi: 10.1016/j.compbiomed.2015.04.006. Epub 2015 Apr 14.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Drozdzal, Michal; Malagelada, Carolina; Radeva, Petia; Segui, Santi; Vitria, Jordi et al.
DOI: 10.1016/j.compbiomed.2015.04.006

Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage.

PMID: 24185700
Journal: NUCLEIC ACIDS RESEARCH
Year: 2014
Reference: Nucleic Acids Res. 2014 Feb 1;42(3):1821-30. doi: 10.1093/nar/gkt1037. Epub 2013 Oct 31.
Impact factor:
Publication type: Paper in international publication
Authors: Diaz-Ingelmo, Ofelia; Fernandez, Xavier; Manichanh, Chaysavanh; Martinez-Garcia, Belen; Roca, Joaquim; Rodriguez-Campos, Antonio et al.
DOI: 10.1093/nar/gkt1037

Detection of wrinkle frames in endoluminal videos using betweenness centrality measures for images.

PMID: 25375680
Journal: IEEE J BIOMED HEALTH
Year: 2014
Reference: IEEE J Biomed Health Inform. 2014 Nov;18(6):1831-8. doi: 10.1109/JBHI.2014.2304179.
Impact factor: 0
Publication type: Paper in international publication
Authors: Segui, Santi, Drozdzal, Michal, Zaytseva, Ekaterina, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al.
DOI: 10.1109/JBHI.2014.2304179

Perception of lactose intolerance in irritable bowel syndrome patients.

PMID: 25089542
Journal: EUR J GASTROEN HEPAT
Year: 2014
Reference: Eur J Gastroenterol Hepatol. 2014 Oct;26(10):1167-75. doi: 10.1097/MEG.0000000000000089.
Impact factor: 2.152
Publication type: Paper in international publication
Authors: Dainese, Raffaella, Casellas, Francesc, Marine-Barjoan, Eugenia, Vivinus-Nebot, Mylene, Schneider, Stephane M, Hebuterne, Xavier, Piche, Thierry et al.
DOI: 10.1097/MEG.0000000000000089

Autoimmune pancreatitis type-1 associated with intraduct papillary mucinous neoplasm: report of two cases.

PMID: 25062884
Journal: PANCREATOLOGY
Year: 2014
Reference: Pancreatology. 2014 Jul-Aug;14(4):316-8. doi: 10.1016/j.pan.2014.04.032. Epub 2014 May 9.
Impact factor: 2.504
Publication type: Letter or abstract
Authors: Vaquero, Eva C, Salcedo, Maria T, Cuatrecasas, Miriam, De Leon, Hannah, Merino, Xavier, Navarro, Salvador, Gines, Angels, Abu-Suboh, Monder, Balsells, Joaquim, Fernandez-Cruz, Laureano et al.
DOI: 10.1016/j.pan.2014.04.032

An update on the use and investigation of probiotics in health and disease.

PMID: 23474420
Journal: GUT
Year: 2013
Reference: Gut. 2013 May;62(5):787-96. doi: 10.1136/gutjnl-2012-302504. Epub 2013 Mar 8.
Impact factor:
Publication type: Review in international publication
Authors: Guarner, Francisco; Guerrant, Richard; Holt, Peter R; Mayer, Emeran A; Quigley, Eamonn Mm; Sanders, Mary Ellen; Sartor, R Balfour; Sherman, Philip M et al.
DOI: 10.1136/gutjnl-2012-302504

Development and testing of a new instrument to measure patient satisfaction with health care in inflammatory bowel disease: the CACHE questionnaire.

PMID: 23429448
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2013
Reference: Inflamm Bowel Dis. 2013 Mar;19(3):559-68. doi: 10.1097/MIB.0b013e31827febd1.
Impact factor:
Publication type: Paper in international publication
Authors: Amo, V; Andreu, M; Aspuru, K; Atienza, R; Barreiro, M; Barrio, J; Bastida, G; Borruel, N; Canas, M M; Casellas, F et al.
DOI: 10.1097/MIB.0b013e31827febd1

The Spanish Pancreatic Club recommendations for the diagnosis and treatment of chronic pancreatitis: part 1 (diagnosis).

PMID: 23395564
Journal: PANCREATOLOGY
Year: 2013
Reference: Pancreatology. 2013 Jan-Feb;13(1):8-17. doi: 10.1016/j.pan.2012.11.309. Epub 2012 Nov 27.
Impact factor:
Publication type: Paper in international publication
Authors: Abad-Gonzalez, A; Aparicio, J R; Aparisi, L; Boadas, J; Boix, E; de Las Heras, G; de-Madaria, E; Dominguez-Munoz, E; Farre, A; Fernandez-Cruz, L et al.
DOI: 10.1016/j.pan.2012.11.309

Linking the gut microbiota to human health.

PMID: 23360877
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2013
Reference: Br J Nutr. 2013 Jan;109 Suppl 2:S21-6. doi: 10.1017/S0007114512005235.
Impact factor:
Publication type: Review in international publication
Authors: Guarner, Francisco; Robles Alonso, Virginia et al.
DOI: 10.1017/S0007114512005235

Categorization and segmentation of intestinal content frames for wireless capsule endoscopy.

PMID: 24218705
Journal: IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE
Year: 2012
Reference: IEEE Trans Inf Technol Biomed. 2012 Nov;16(6):1341-52.
Impact factor: 1.676
Publication type: Paper in international publication
Authors: Segui, Santi, Drozdzal, Michal, Vilarino, Fernando, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al.
DOI: 10.1109/TITB.2012.2221472

Effect of a mixture of inulin and fructo-oligosaccharide on Lactobacillus and Bifidobacterium intestinal microbiota of patients receiving radiotherapy: a randomised, double-blind, placebo-controlled trial.

PMID: 23588438
Journal: Nutricion Hospitalaria
Year: 2012
Reference: Nutr Hosp. 2012 Nov-Dec;27(6):1908-15. doi: 10.3305/nh.2012.27.6.5992.
Impact factor: 1.12
Publication type: Paper in international publication
Authors: Lozano, M A, Moreno, Y, Paron, L, de la Cuerda, C, Breton, I, Camblor, M, Garcia-Hernandez, J, Guarner, F, Hernandez, M, Velasco, C et al.
DOI: 10.3305/nh.2012.27.6.5992

Ustekinumab induction and maintenance therapy in refractory Crohn's disease.

PMID: 23075178
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2012
Reference: N Engl J Med. 2012 Oct 18;367(16):1519-28. doi: 10.1056/NEJMoa1203572.
Impact factor: 53.298
Publication type: Paper in international publication
Authors: Fishman, S, Sandborn, William J, Gasink, Christopher, Gao, Long-Long, Blank, Marion A, Johanns, Jewel, Guzzo, Cynthia, Sands, Bruce E, Hanauer, Stephen B, Targan, Stephan et al.
DOI: 10.1056/NEJMoa1203572

Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1{alpha} in acinar cell homeostasis.

PMID: 21948943
Journal: GUT
Year: 2012
Reference: Gut. 2012 Aug;61(8):1187-96. doi: 10.1136/gutjnl-2011-300360. Epub 2011 Sep 23.
Impact factor: 10.111
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/gutjnl-2011-300360

Development and validation of the Crohn's disease perceived work disability questionnaire.

PMID: 21287662
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2011
Reference: Inflamm Bowel Dis. 2011 Nov;17(11):2350-7. doi: 10.1002/ibd.21604. Epub 2011 Feb 1.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1002/ibd.21604

Eosinophils express muscarinic receptors and corticotropin-releasing factor to disrupt the mucosal barrier in ulcerative colitis.

PMID: 21277851
Journal: GASTROENTEROLOGY
Year: 2011
Reference: Gastroenterology. 2011 May;140(5):1597-607. Epub 2011 Jan 26.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1053/j.gastro.2011.01.042

[Information for patients. Functional abdominal pain].

PMID: 21951120
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2011
Reference: Rev Esp Enferm Dig. 2011 Sep;103(9):492. doi: 10.4321/s1130-01082011000900010.
Impact factor: 1.13
Publication type: Letter or abstract
Authors: Accarino, Anna et al.
DOI: 10.4321/s1130-01082011000900010

Postoperative pain after haemorrhoidectomy: role of impaired evacuation.

PMID: 20402734
Journal: Colorectal Disease
Year: 2011
Reference: Colorectal Dis. 2011 Aug;13(8):926-9. doi: 10.1111/j.1463-1318.2010.02280.x. Epub 2010 Apr 5.
Impact factor: 2.41
Publication type: Paper in international publication
Authors: , , et al.
DOI: 10.1111/j.1463-1318.2010.02280.x

Colonic Responses to Gas Loads in Subgroups of Patients With Abdominal Bloating.

PMID: 20179685
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2010
Reference: Am J Gastroenterol. 2010 Apr;105(4):876-82. Epub 2010 Feb 23.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/ajg.2010.75

Constipation: a potential cause of pelvic floor damage?

PMID: 19761491
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2010
Reference: Neurogastroenterol Motil. 2010 Feb;22(2):150-3, e48. Epub 2009 Sep 17.
Impact factor:
Publication type: Paper in international publication
Authors: Amselem, C; Azpiroz, F; Fernandez-Fraga, X; Malagelada, J-R; Puigdollers, A; Sala, C; Videla, S; Whorwell, P et al.
DOI: 10.1111/j.1365-2982.2009.01409.x

[Gastroparesis].

PMID: 20524764
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2010
Reference: Rev Esp Enferm Dig. 2010 May;102(5):337. doi: 10.4321/s1130-01082010000500010.
Impact factor: 0.994
Publication type: Letter or abstract
Authors: Accarino, A et al.
DOI: 10.4321/s1130-01082010000500010

Fatigue as a determinant of health in patients with celiac disease.

PMID: 19935081
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2010
Reference: J Clin Gastroenterol. 2010 Jul;44(6):423-7. doi: 10.1097/MCG.0b013e3181c41d12.
Impact factor: 2.207
Publication type: Paper in international publication
Authors: Jorda, Francesc Casellas, Lopez Vivancos, Josefa et al.
DOI: 10.1097/MCG.0b013e3181c41d12

Predicting Early Mortality After Acute Variceal Hemorrhage Based on Classification and Regression Tree Analysis.

PMID: 19699816
Journal: Clinical Gastroenterology and Hepatology
Year: 2009
Reference: Clin Gastroenterol Hepatol. 2009 Dec;7(12):1347-54.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.cgh.2009.08.011

International validation of a health-related quality of life questionnaire in patients with erosive gastro-oesophageal reflux disease.

PMID: 19183145
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2009
Reference: Aliment Pharmacol Ther. 2009 Mar 15;29(6):615-25.
Impact factor:
Publication type: Paper in international publication
Authors: Chassany, O; Devault, K R; Doerfler, H; Gebauer, U; Holtmann, G; Malagelada, J R; Schmitt, H et al.
DOI: 10.1111/j.1365-2036.2008.03922.x

Inflammatory disease processes and interactions with nutrition.

PMID: 19586558
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2009
Reference: Br J Nutr. 2009 May;101 Suppl 1:S1-45.
Impact factor:
Publication type: Review in international publication
Authors: Albers, R; Antoine, J-M; Blum, S; Bourdet-Sicard, R; Calder, P C; Ferns, G A; Folkerts, G; Friedmann, P S; Frost, G S; Guarner, F et al.
DOI: 10.1017/S0007114509377867

Prebiotics, probiotics and helminths: the 'natural' solution?

PMID: 19786773
Journal: DIGESTIVE DISEASES
Year: 2009
Reference: Dig Dis. 2009;27(3):412-7.
Impact factor:
Publication type: Paper in international publication
Authors: Guarner, Francisco et al.
DOI: 10.1159/000228582

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News

A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.