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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Geographic distribution and phenotype of European people with cystic fibrosis carrying A1006E mutation.

PMID: 35032736
Journal: RESPIRATORY MEDICINE
Year: 2022
Reference: Respir Med. 2022 Feb;192:106736. doi: 10.1016/j.rmed.2022.106736. Epub 2022 Jan 6.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Fernandez, Antonio; Asensio de la Cruz, Oscar; Calderazzo, Maria Adelaide; Carnovale, Vincenzo; Castillo-Corullon, Silvia; Cimino, Giuseppe; de Asis Sanchez-Martinez, Francisco; Garcia-Marcos, Patricia W; Gartner, Silvia; Glover, Guillermo et al.
DOI: 10.1016/j.rmed.2022.106736

Are short courses of antibiotic therapy as effective as standard courses for COPD exacerbations? A systematic review and meta-analysis.

PMID: 35032637
Journal: PULMONARY PHARMACOLOGY & THERAPEUTICS
Year: 2022
Reference: Pulm Pharmacol Ther. 2022 Feb;72:102111. doi: 10.1016/j.pupt.2022.102111. Epub 2022 Jan 13.
Impact factor:
Publication type: Review in international publication
Authors: Cordoba, Gloria; Llor, Carl; Mesquita, Patrick; Miravitlles, Marc; Moragas, Ana et al.
DOI: 10.1016/j.pupt.2022.102111

Opinions and Attitudes of Pulmonologists About Augmentation Therapy in Patients with Alpha-1 Antitrypsin Deficiency. A Survey of the EARCO Group.

PMID: 35023913
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2022
Reference: Int J Chron Obstruct Pulmon Dis. 2022 Jan 5;17:53-64. doi: 10.2147/COPD.S346051. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Albert, Anna; Boeselt, Tobias; Cassel, Werner; Clarenbach, Christian; Ferreira, Francini; Greulich, Timm; Klemmer, Andreas; Miravitlles, Marc; Peychev, Erika; Torres-Duran, Maria L et al.
DOI: 10.2147/COPD.S346051

Evolving mortality and clinical outcomes of hospitalized subjects during successive COVID-19 waves in Catalonia, Spain.

PMID: 35018339
Journal: Journal of Epidemiology and Global Health
Year: 2022
Reference: Glob Epidemiol. 2022 Jan 7:100071. doi: 10.1016/j.gloepi.2022.100071.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Argimon, Josep M; Auguet, Teresa; Cos, Francesc X; Ferrer, Jaume; Gasa, Merce; Gudiol, Carlota; Khunti, Kamlesh; Lerida, Ana; Mateu, Lourdes et al.
DOI: 10.1016/j.gloepi.2022.100071

Free Airway C4d after Lung Transplantation - A Quantitative Analysis of Bronchoalveolar Lavage Fluid

PMID: 33217540
Journal: TRANSPLANT IMMUNOLOGY
Year: 2021
Reference: Transpl Immunol. 2021 Feb;64:101352. doi: 10.1016/j.trim.2020.101352. Epub 2020 Nov 17.
Impact factor:
Publication type: Paper in international publication
Authors: Ambrocio, Gene P L; Beeckmans, Hanne; Ceulemans, Laurens J; Erp, Hanneke Kwakkel-Van; Heigl, Tobias; Kaes, Janne; Neyrinck, Arne P; Ordies, Sofie; Sacreas, Annelore; Saez-Gimenez, Berta et al.
DOI: 10.1016/j.trim.2020.101352

Withdrawal of inhaled corticosteroids versus continuation of triple therapy in patients with COPD in real life: observational comparative effectiveness study.

PMID: 33478491
Journal: RESPIRATORY RESEARCH
Year: 2021
Reference: Respir Res. 2021 Jan 21;22(1):25. doi: 10.1186/s12931-021-01615-0.
Impact factor:
Publication type: Paper in international publication
Authors: Dandurand, Ronald J; Lapperre, Therese; Lucas, Sarah; Magnussen, Helgo; Miravitlles, Marc; Papi, Alberto; Price, David; Quint, Jennifer K; Roche, Nicolas et al.
DOI: 10.1186/s12931-021-01615-0

Blood Eosinophil Counts and Their Variability and Risk of Exacerbations in COPD: A Population-Based Study.

PMID: 32061402
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Jan;57(1):13-20. doi: 10.1016/j.arbres.2019.12.015. Epub 2020 Feb 13.
Impact factor:
Publication type: Paper in national publication
Authors: Alcazar, Bernardino; Miravitlles, Marc; Monteagudo, Monica; Solntseva, Iryna et al.
DOI: 10.1016/j.arbres.2019.12.015

C-reactive protein point of care testing: the answer to antibiotic prescribing in ambulatory patients with exacerbations of chronic obstructive pulmonary disease?

PMID: 32476530
Journal: Expert Review of Respiratory Medicine
Year: 2021
Reference: Expert Rev Respir Med. 2021 Jan;15(1):1-3. doi: 10.1080/17476348.2020.1776611. Epub 2020 Jun 4.
Impact factor:
Publication type: Editorail in international publication
Authors: Llor, Carl; Miravitlles, Marc et al.
DOI: 10.1080/17476348.2020.1776611

Factors that determine the loss of control when reducing therapy by steps in the treatment of moderate-severe asthma in standard clinical practice: A multicentre Spanish study.

PMID: 31350049
Journal: REVISTA CLINICA ESPANOLA
Year: 2020
Reference: Rev Clin Esp (Barc). 2020 Mar;220(2):86-93. doi: 10.1016/j.rce.2019.05.004. Epub 2019 Jul 23.
Impact factor: 1.304
Publication type: Paper in national publication
Authors: Santiago, Aparicio Espanol, Marta, Velasco Azagra, Antonio, Alvarez Fernandez Jose, Sara, Acero Sainz, Rosa, Blanco Gonzalez M, Estela, Gomez Nieves Maria, Diego, Aisa Carpio, Nuria, Angrill Selles, Cristina, Berastegui Garcia, Astrid, Crespo Lessmann et al.
DOI: 10.1016/j.rce.2019.05.004

Association between reperfusion therapy and outcomes in patients with acute pulmonary embolism and right heart thrombi.

PMID: 32430430
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2020
Reference: Eur Respir J. 2020 Nov 5;56(5). pii: 13993003.00538-2020. doi: 10.1183/13993003.00538-2020. Print 2020 Nov.
Impact factor: 12.339
Publication type: Letter whit IF
Authors: Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge-Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio et al.
DOI: 10.1183/13993003.00538-2020

A Systematically Derived Exposure Assessment Instrument for Chronic Hypersensitivity Pneumonitis.

PMID: 31958445
Journal: CHEST
Year: 2020
Reference: Chest. 2020 Jun;157(6):1506-1512. doi: 10.1016/j.chest.2019.12.018. Epub 2020 Jan 17.
Impact factor: 8.308
Publication type: Review in international publication
Authors: Barber, Christopher M, Behr, Jurgen, Bonella, Francesco, Corte, Tamera, Costabel, Ulrich, Cottin, Vincent, Crestani, Bruno, Dalphin, Jean-Charles, Flaherty, Kevin R, Goh, Nicole et al.
DOI: 10.1016/j.chest.2019.12.018

The immunomodulatory effects of diesel exhaust particles in asthma.

PMID: 33618472
Journal: ENVIRONMENTAL POLLUTION
Year: 2020
Reference: Environ Pollut. 2020 Aug;263(Pt A):114600. doi: 10.1016/j.envpol.2020.114600. Epub 2020 Apr 20.
Impact factor: 6.792
Publication type: Paper in international publication
Authors: de Homdedeu M, Cruz, Mj, Sanchez-Diez, S, I, Ojanguren, Romero-Mesones, C, J, Vanoirbeek, Velde G, Vande, X, Munoz et al.
DOI: 10.1016/j.envpol.2020.114600

Microbial contamination of liposomal amphotericin B nebuliser devices in lung transplant patients.

PMID: 29754979
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2019
Reference: Enferm Infecc Microbiol Clin. 2019 Mar;37(3):211-212. doi: 10.1016/j.eimc.2018.04.004. Epub 2018 May 10.
Impact factor: 1.685
Publication type: Paper in national publication
Authors: Fernandez-Huerta, Miguel, Escobar, Roser, Monforte, Victor, Rodriguez, Virginia et al.
DOI: 10.1016/j.eimc.2018.04.004

Practical Guide to the Identification and Diagnosis of Asthma-COPD Overlap (ACO).

PMID: 30789039
Journal: COPD-Journal of Chronic Obstructive Pulmonary Disease
Year: 2019
Reference: COPD. 2019 Feb;16(1):1-7. doi: 10.1080/15412555.2019.1575802. Epub 2019 Feb 21.
Impact factor: 2.503
Publication type: Paper in international publication
Authors: Nunez, Alexa, Sarasate, Mikel, Loeb, Eduardo, Esquinas, Cristina, Miravitlles, Marc, Barrecheguren, Miriam et al.
DOI: 10.1080/15412555.2019.1575802

Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma?

PMID: 29956349
Journal: ALLERGY
Year: 2019
Reference: Allergy. 2019 Feb;74(2):261-272. doi: 10.1111/all.13542. Epub 2018 Nov 25.
Impact factor: 6.771
Publication type: Paper in international publication
Authors: Hurdubaea, L, Vandenplas, O, Godet, J, Paula, Kauppi, de Blay, F, Laura, Hurdubaea, Rolf, Merget, Preisser, Alexandra M, Piero, Maestrelli, Paola, Mason et al.
DOI: 10.1111/all.13542

Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials.

PMID: 30723730
Journal: ERJ open research
Year: 2019
Reference: ERJ Open Res. 2019 Feb 1;5(1). pii: 00147-2018. doi: 10.1183/23120541.00147-2018. eCollection 2019 Feb.
Impact factor: 0
Publication type: Paper in international publication
Authors: Robinson, Phil, Snijders, Deborah, Yiallouros, Panayiotis, Carr, Siobhan B, Rademacher, Jessica, Polverino, Eva, Pohunek, Petr, Philipsen, Lue Katrine Drasbaek, Lucas, Jane S, Gahleitner, Florian et al.
DOI: 10.1183/23120541.00147-2018

The Role of Fixed-Dose Dual Bronchodilator Therapy in Treating COPD.

PMID: 29305841
Journal: AMERICAN JOURNAL OF MEDICINE
Year: 2018
Reference: Am J Med. 2018 Jun;131(6):608-622. doi: 10.1016/j.amjmed.2017.12.018. Epub 2018 Jan 3.
Impact factor:
Publication type: Review in international publication
Authors: Anzueto, Antonio; Miravitlles, Marc et al.
DOI: 10.1016/j.amjmed.2017.12.018

Macrolides, mucoactive drugs and adherence for the management of bronchiectasis.

PMID: 29301926
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Jan 4;51(1). pii: 51/1/1702033. doi: 10.1183/13993003.02033-2017. Print 2018 Jan.
Impact factor:
Publication type: Letter or abstract
Authors: Chalmers, James D; Polverino, Eva et al.
DOI: 10.1183/13993003.02033-2017

Expansion of a CD26(low) effector TH subset and reduction of circulating levels of sCD26 in stable allergic asthma in adults.

PMID: 29297467
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2018
Reference: J Investig Allergol Clin Immunol. 2018;28(2):113-125. doi: 10.18176/jiaci.0224. Epub 2018 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Andrade-Bulos, L J; Arias, P; Cruz, M J; Garcia-Gonzalez, M A; Gonzalez-Barcala, F J; Linares, T; Nieto-Fontarigo, J J; Nogueira, M; Salgado, F J; San-Jose, M E et al.
DOI: 10.18176/jiaci.0224

Combining case-finding methods for COPD in primary care: a large, two-stage design study.

PMID: 29297434
Journal: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Year: 2018
Reference: Int J Tuberc Lung Dis. 2018 Jan 1;22(1):106-111. doi: 10.5588/ijtld.17.0334.
Impact factor:
Publication type: Paper in international publication
Authors: Miravitlles, M; Molina, J; Soriano, J B et al.
DOI: 10.5588/ijtld.17.0334

Prescription of physical activity in chronic obstructive pulmonary disease... and beyond COPD.

PMID: 28143651
Journal: MEDICINA CLINICA
Year: 2017
Reference: Med Clin (Barc). 2017 Jul 7;149(1):24-25. doi: 10.1016/j.medcli.2016.12.014. Epub 2017 Jan 28.
Impact factor:
Publication type: Paper in national publication
Authors: Miravitlles, Marc; Pleguezuelos, Eulogio et al.
DOI: 10.1016/j.medcli.2016.12.014

Restrictive Allograft Syndrome And Idiopathic Pleuroparenchymal Fibroelastosis: Do They Really Have The Same Histology?

PMID: 28120410
Journal: HISTOPATHOLOGY
Year: 2017
Reference: Histopathology. 2017 Jun;70(7):1107-1113. doi: 10.1111/his.13171. Epub 2017 Mar 20.
Impact factor:
Publication type: Paper in international publication
Authors: Khiroya, Reena; Monforte, Victor; Montero, M Angeles; Nicholson, Andrew G; Osadolor, Tina; Rice, Alexandra; Robertus, Jan Lukas; Roman, Antonio; Salcedo, M Teresa et al.
DOI: 10.1111/his.13171

Genetic diagnosis of alpha1-antitrypsin deficiency using DNA from buccal swab and serum samples.

PMID: 28107169
Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Year: 2017
Reference: Clin Chem Lab Med. 2017 Aug 28;55(9):1276-1283. doi: 10.1515/cclm-2016-0842.
Impact factor:
Publication type: Paper in international publication
Authors: Barrecheguren, Miriam; Belmonte, Irene; Esquinas, Cristina; Miravitlles, Marc; Rodriguez, Esther; Rodriguez-Frias, Francisco et al.
DOI: 10.1515/cclm-2016-0842

Is aclidinium alone or combined with a LABA a rational choice for symptomatic COPD patients?

PMID: 28100244
Journal: RESPIRATORY RESEARCH
Year: 2017
Reference: Respir Res. 2017 Jan 18;18(1):19. doi: 10.1186/s12931-017-0506-0.
Impact factor:
Publication type: Review in international publication
Authors: Blasi, F; Canonica, G W; Miravitlles, M et al.
DOI: 10.1186/s12931-017-0506-0

A rapid test for soy aeroallergens exposure assessment.

PMID: 24533134
Journal: PLOS ONE
Year: 2014
Reference: PLoS One. 2014 Feb 12;9(2):e88676. doi: 10.1371/journal.pone.0088676. eCollection 2014.
Impact factor: 3.534
Publication type: Paper in international publication
Authors: Morell, Ferran, Gomez-Olles, Susana, Villalbi, Joan R, Munoz, Xavier, Cruz, Maria-Jesus, Alvarez-Simon, Daniel, Untoria, Maria-Dolores et al.
DOI: 10.1371/journal.pone.0088676

Future Directions in Lung Transplant.

PMID: 24360986
Journal: ARCH BRONCONEUMOL
Year: 2014
Reference: Arch Bronconeumol. 2014 Jan;50(1):1-2. doi: 10.1016/j.arbres.2013.11.011. Epub 2013 Dec 19.
Impact factor: 1.816
Publication type: Editorial in national publication
Authors: Roman, Antonio, Sole, Joan et al.
DOI: 10.1016/j.arbres.2013.11.011

Pharmacokinetic study of conversion from tacrolimus twice-daily to tacrolimus once-daily in stable lung transplantation.

PMID: 24492423
Journal: TRANSPLANTATION
Year: 2014
Reference: Transplantation. 2014 Feb 15;97(3):358-62. doi: 10.1097/01.TP.0000435699.69266.66.
Impact factor: 3.535
Publication type: Paper in international publication
Authors: Mendez, Alejandra, Berastegui, Cristina, Lopez-Meseguer, Manuel, Monforte, Victor, Bravo, Carlos, Blanco, Albert, Camos, Silvia, Pou, Leonor, Roman, Antonio et al.
DOI: 10.1097/01.TP.0000435699.69266.66

Successful pregnancy in a patient with pulmonary hypertension associated with mixed collagen vascular disease.

PMID: 24456447
Journal: J OBSTET GYNAECOL
Year: 2014
Reference: J Obstet Gynaecol. 2014 Feb;34(2):191. doi: 10.3109/01443615.2012.706663.
Impact factor: 0.604
Publication type: Paper in international publication
Authors: Goya, M, Meseguer, M L, Merced, C, Suy, A, Monforte, V, Domingo, E, Cabero, L, Roman, A et al.
DOI: 10.3109/01443615.2012.706663

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.