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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension. Are Intravascular Ultrasound and Stents Helpful?

PMID: NOPMID0098
Journal: International Journal of Pulmonary & Respiratory Sciences
Year: 2022
Reference: Int J Pul & Res Sci. 2022; 6(1): 555677. DOI: 10.19080/IJOPRS.2022.06.555677
Impact factor:
Publication type: Paper in international publication
Authors: Bravo, Carles; Calabuig, Alvaro; Domingo, Enric; Garcia, Bruno; Grignola, Juan Carlos; López Meseguer, Manuel; Roman, Antonio et al.
DOI: 10.19080/IJOPRS.2022.06.555677

Pulmonary Cryptococcosis Mimicking Lung Cancer

PMID: NOPMID0099
Journal: Open Respiratory Archives
Year: 2022
Reference: Open Respir Arch. 2022;4(2):100154. doi:10.1016/j.opresp.2021.100154
Impact factor:
Publication type: Letter whit IF
Authors: Eremiev, Simeon; Espejo, David; Martín-Gómez, Maria Teresa; Ojanguren, Iñigo; Pilia, Maria Florencia; Ruiz, Isabel; Sempere, Abiu et al.
DOI: 10.1016/j.opresp.2021.100154

A randomized controlled trial of liposomal cyclosporine A for inhalation in the prevention of bronchiolitis obliterans syndrome following lung transplantation.

PMID: 34587371
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Jan;22(1):222-229. doi: 10.1111/ajt.16858. Epub 2021 Oct 18.
Impact factor: 8.086
Publication type: Paper in international publication
Authors: Knoop, Christiane; Jaksch, Peter; Parmar, Jasvir; Ussetti, Piedad; Sole, Amparo; Muller-Quernheim, Joachim; Kessler, Romain; Wirtz, Hubert; Boerner, Gerhard; Denk, Oliver et al.
DOI: 10.1111/ajt.16858

EAACI position paper on the clinical use of the bronchial allergen challenge: unmet needs and research priorities.

PMID: 34978085
Journal: ALLERGY
Year: 2022
Reference: Allergy. 2022 Jun;77(6):1667-1684. doi: 10.1111/all.15203. Epub 2022 Jan 20.
Impact factor: 13.146
Publication type: Paper in international publication
Authors: Agache, Ioana; Antolin-Amerigo, Dario; de Blay, Frederic; Boccabella, Cristina; Caruso, Cristiano; Chanez, Pascal; Couto, Mariana; Covar, Ronina; Doan, Serge; Fauquert, Jean-Luc et al.
DOI: 10.1111/all.15203

Clinical characteristics in 545 patients with severe asthma on biological treatment during the COVID-19 outbreak.

PMID: 33045398
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2021
Reference: J Allergy Clin Immunol Pract. 2021 Jan;9(1):487-489.e1. doi: 10.1016/j.jaip.2020.09.050. Epub 2020 Oct 9.
Impact factor:
Publication type: Paper in international publication
Authors: Arismendi, Ebymar; Barranco, Pilar; Bobolea, Irina; Curto, Elena; Del Pozo, Victoria; Dominguez-Ortega, Javier; Gonzalez-Barcala, Francisco Javier; Martinez-Rivera, Carlos; Mullol, Joaquin; Munoz, Xavier et al.
DOI: 10.1016/j.jaip.2020.09.050

Efficacy and safety of TOBI Podhaler(R) in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study.

PMID: 32855225
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2021
Reference: Eur Respir J. 2021 Jan 5;57(1). pii: 13993003.01451-2020. doi: 10.1183/13993003.01451-2020. Print 2021 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Angyalosi, Gerhild; Blasi, Francesco; Chalmers, James D; Elborn, Stuart J; Goossens, Herman; Haworth, Charles S; Hill, Adam T; Loebinger, Michael R; Pathan, Rashidkhan; Polverino, Eva et al.
DOI: 10.1183/13993003.01451-2020

The HIPARCO-2 study: long-term effect of continuous positive airway pressure on blood pressure in patients with resistant hypertension: a multicenter prospective study.

PMID: 33239552
Journal: JOURNAL OF HYPERTENSION
Year: 2021
Reference: J Hypertens. 2021 Feb 1;39(2):302-309. doi: 10.1097/HJH.0000000000002664.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Cambriles, Trinidad Diaz; Campos-Rodriguez, Francisco; de la Pena, Monica; Garcia-Ortega, Alberto; Garcia-Rio, Francisco; Gonzalez, Monica; Lloberes, Patricia; Manas, Eva; Manas, Pedro et al.
DOI: 10.1097/HJH.0000000000002664

COVID-19 in Solid Organ Transplantation: A Matched Retrospective Cohort Study and Evaluation of Immunosuppression Management.

PMID: 32941394
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Jan 1;105(1):138-150. doi: 10.1097/TP.0000000000003460.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Martinez, Carla; Anton, Andres; Berastegui, Cristina; Castells, Lluis; Del-Rio-Gutierrez, Jose-Manuel; Domenech, Laura; Garcia-Garcia, Sonia; Garcia-Ortega, Patricia; Gomez-Ganda, Laura; Gorgas-Torner, Maria-Queralt et al.
DOI: 10.1097/TP.0000000000003460

Feasibility of computerized adventitious respiratory sounds to assess the effects of airway clearance techniques in patients with bronchiectasis.

PMID: 30669914
Journal: PHYSIOTHERAPY THEORY AND PRACTICE
Year: 2020
Reference: Physiother Theory Pract. 2020 Nov;36(11):1245-1255. doi: 10.1080/09593985.2019.1566945. Epub 2019 Jan 23.
Impact factor: 1.624
Publication type: Paper in international publication
Authors: Marques, Alda, Torres, Antoni, Polverino, Eva, Herrero-Cortina, Beatriz, Oliveira, Ana, Gomez-Trullen, Eva Maria et al.
DOI: 10.1080/09593985.2019.1566945

[Assessment model for evaluating the preparedness plan for COVID-19 in a tertiary care hospital].

PMID: 33127345
Journal: Journal of healthcare quality research
Year: 2020
Reference: J Healthc Qual Res. 2020 Nov - Dec;35(6):339-347. doi: 10.1016/j.jhqr.2020.10.001. Epub 2020 Oct 10.
Impact factor: 0
Publication type: Paper in national publication
Authors: Llorente-Parrado, C, Mejon-Berges, R, Cossio-Gil, Y, Romea-Lecumberri, M S, Roman-Broto, A, Barba-Flores, M A, Salazar-Soler, A et al.
DOI: 10.1016/j.jhqr.2020.10.001

The Experience of COPD Patients in Lockdown Due to the COVID-19 Pandemic.

PMID: 33122900
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: Int J Chron Obstruct Pulmon Dis. 2020 Oct 23;15:2621-2627. doi: 10.2147/COPD.S268421. eCollection 2020.
Impact factor: 2.772
Publication type: Paper in international publication
Authors: Moreno, Eva, Pleguezuelos, Eulogio, Del Carmen, Amin, Ovejero, Laura, Serra-Prat, Mateu, Palomera, Elisabet, Garnacho-Castano, Manuel Vicente, Loeb, Eduardo, Farago, Georgina, Miravitlles, Marc et al.
DOI: 10.2147/COPD.S268421

Trends in Diagnosis of Alpha-1 Antitrypsin Deficiency Between 2015 and 2019 in a Reference Laboratory.

PMID: 33116457
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: Int J Chron Obstruct Pulmon Dis. 2020 Oct 7;15:2421-2431. doi: 10.2147/COPD.S269641. eCollection 2020.
Impact factor: 2.772
Publication type: Paper in international publication
Authors: Belmonte, Irene, Nunez, Alexa, Barrecheguren, Miriam, Esquinas, Cristina, Pons, Monica, Lopez-Martinez, Rosa M, Ruiz, Gerard, Blanco-Grau, Albert, Genesca, Joan, Ferrer, Roser et al.
DOI: 10.2147/COPD.S269641

Diagnosis of occupational hypersensitivity pneumonitis.

PMID: 30649011
Journal: Current Opinion in Allergy and Clinical Immunology
Year: 2019
Reference: Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):105-110. doi: 10.1097/ACI.0000000000000511.
Impact factor: 3.014
Publication type: Paper in international publication
Authors: Cruz, Maria-Jesus, Morell, Ferran, Ojanguren, Inigo et al.
DOI: 10.1097/ACI.0000000000000511

Concomitant hypersensitivity pneumonitis and occupational asthma caused by two different etiological agents.

PMID: 30641195
Journal: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Year: 2019
Reference: Ann Allergy Asthma Immunol. 2019 Apr;122(4):424-425.e1. doi: 10.1016/j.anai.2019.01.007. Epub 2019 Jan 12.
Impact factor: 3.56
Publication type: Paper in international publication
Authors: Solana, E, Cruz, M J, Romero-Mesones, C, Munoz, X et al.
DOI: 10.1016/j.anai.2019.01.007

Clinical Practice Guideline recommendations on examination of the upper airway for adults with suspected obstructive sleep apnoea-hypopnoea syndrome.

PMID: 30616837
Journal: Acta otorrinolaringologica espanola
Year: 2019
Reference: Acta Otorrinolaringol Esp. 2019 Nov - Dec;70(6):364-372. doi: 10.1016/j.otorri.2018.06.008. Epub 2019 Jan 5.
Impact factor: 0
Publication type: Paper in national publication
Authors: Esteller, Eduard, Carrasco, Marina, Diaz-Herrera, Miguel Angel, Sampol, Gabriel, Juvanteny, Joan, Sieira, Ramon, Farre, Alex, Vilaseca, Isabel, Vila, Javier et al.
DOI: 10.1016/j.otorri.2018.06.008

Good long-term adherence to continuous positive airway pressure therapy in patients with resistant hypertension and sleep apnea.

PMID: 30604577
Journal: JOURNAL OF SLEEP RESEARCH
Year: 2019
Reference: J Sleep Res. 2019 Oct;28(5):e12805. doi: 10.1111/jsr.12805. Epub 2019 Jan 2.
Impact factor: 3.432
Publication type: Paper in international publication
Authors: Lloberes, Patricia, Campos-Rodriguez, Francisco, Navarro-Soriano, Cristina, Reyes-Nunez, Nuria, Torres, Gerard, Caballero-Eraso, Candela, Masa, Juan F, Gonzalez, Monica, Manas, Eva, de la Pena, Monica et al.
DOI: 10.1111/jsr.12805

Echocardiographic changes with non-invasive ventilation and CPAP in obesity hypoventilation syndrome.

PMID: 29146865
Journal: THORAX
Year: 2018
Reference: Thorax. 2018 Apr;73(4):361-368. doi: 10.1136/thoraxjnl-2017-210642. Epub 2017 Nov 16.
Impact factor: 8.272
Publication type: Paper in international publication
Authors: Mogollon, Maria Victoria, Sanchez-Quiroga, M-Angeles, Gomez de Terreros, Javier, Romero, Auxiliadora, Caballero, Candela, Teran-Santos, Joaquin, Alonso-Alvarez, Maria L, Gomez-Garcia, Teresa, Gonzalez, Monica, Lopez-Martinez, Soledad et al.
DOI: 10.1136/thoraxjnl-2017-210642

QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.

PMID: 29880656
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Aug 16;52(2). pii: 13993003.00537-2018. doi: 10.1183/13993003.00537-2018. Print 2018 Aug.
Impact factor: 12.242
Publication type: Letter or abstract
Authors: Burman, Matthew, Guglielmetti, Lorenzo, Tiberi, Simon, Kristjansson, Mar, McLaughlin, Anne Marie, Chiappini, Elena, Confalonieri, Marco, Del Bravo, Paola, Gualano, Gina, Motta, Ilaria et al.
DOI: 10.1183/13993003.00537-2018

Study of CD27 and CCR4 Markers on Specific CD4(+) T-Cells as Immune Tools for Active and Latent Tuberculosis Management.

PMID: 30687314
Journal: Frontiers in Immunology
Year: 2018
Reference: Front Immunol. 2019 Jan 9;9:3094. doi: 10.3389/fimmu.2018.03094. eCollection 2018.
Impact factor: 5.511
Publication type: Paper in international publication
Authors: Prat, Cristina, Dominguez, Jose, Sabria, Josefina, Luque-Chacon, Lydia, Lacoma, Alicia, Gonzalez-Diaz, Yoel D, Latorre, Irene, Muriel-Moreno, Beatriz, Villar-Hernandez, Raquel, Vila, Sergi et al.
DOI: 10.3389/fimmu.2018.03094

Duration of the efficacy of omalizumab after treatment discontinuation in 'real life' severe asthma.

PMID: 29079610
Journal: THORAX
Year: 2018
Reference: Thorax. 2018 Aug;73(8):782-784. doi: 10.1136/thoraxjnl-2017-210017. Epub 2017 Oct 27.
Impact factor: 9.655
Publication type: Letter or abstract
Authors: Vennera, Maria Del Carmen, Sabadell, Carlos, Picado, Cesar, Alvarez Puebla, M J, Irigaray, R, Martinez-Moragon, E, Pellicer, C, Martinez, C, Munoz, X, Canete, C et al.
DOI: 10.1136/thoraxjnl-2017-210017

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research.

PMID: 28596426
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2017
Reference: Eur Respir J. 2017 Jun 8;49(6). pii: 49/6/1700051. doi: 10.1183/13993003.00051-2017. Print 2017 Jun.
Impact factor: 10.569
Publication type: Paper in international publication
Authors: Dimakou, Katerina, Elborn, J Stuart, Feldman, Charles, Flume, Patrick, Goeminne, Pieter C, Loebinger, Michael R, Menendez, Rosario, Morgan, Lucy, Murris, Marlene, Polverino, Eva et al.
DOI: 10.1183/13993003.00051-2017

An homozygous mutation in KCNK3 is associated with an aggressive form of hereditary pulmonary arterial hypertension.

PMID: 27649371
Journal: CLINICAL GENETICS
Year: 2017
Reference: Clin Genet. 2017 Mar;91(3):453-457. doi: 10.1111/cge.12869. Epub 2016 Nov 4.
Impact factor: 3.326
Publication type: Paper in international publication
Authors: Roman Broto, A, Lapunzina Abadia, P, Escribano Subia, P, Lopez Meseguer, M, Gordo Trujillo, G, Palomino Doza, J, Navas Tejedor, P, Tenorio Castano, J, Arias Lajara, P et al.
DOI: 10.1111/cge.12869

Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency.

PMID: 29238183
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2017
Reference: Int J Chron Obstruct Pulmon Dis. 2017 Nov 29;12:3381-3390. doi: 10.2147/COPD.S145445. eCollection 2017.
Impact factor: 3.157
Publication type: Paper in international publication
Authors: Esquinas, Cristina, Janciauskiene, Sabina, Gonzalo, Ricardo, Mas de Xaxars, Gemma, Olejnicka, Beata, Belmonte, Irene, Barrecheguren, Miriam, Rodriguez, Esther, Nunez, Alexa, Rodriguez-Frias, Francisco et al.
DOI: 10.2147/COPD.S145445

Lorraine Racusen and Kim Solez Awarded the Gold Medal of the Catalan Transplant Society.

PMID: 29198652
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2240-2242. doi: 10.1016/j.transproceed.2017.09.044.
Impact factor: 0.908
Publication type: Letter or abstract
Authors: Seron, D, Roman, A et al.
DOI: 10.1016/j.transproceed.2017.09.044

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.