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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Sleep increases leaks and asynchronies during home noninvasive ventilation: a polysomnographic study.

PMID: 34314351
Journal: Journal of Clinical Sleep Medicine
Year: 2022
Reference: J Clin Sleep Med. 2022 Jan 1;18(1):225-233. doi: 10.5664/jcsm.9546.
Impact factor: 4.062
Publication type: Paper in international publication
Authors: Marti, Sergi; Ferre, Alex; Sampol, Gabriel; Pallero, Mercedes; Romero, Odile; Ferrer, Jaume; Sampol, Julia et al.
DOI: 10.5664/jcsm.9546

Reconciling short-term clinical and Immunological outcomes of SARS-CoV-2 vaccination in Solid Organ Transplant recipients.

PMID: 34554648
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5.
Impact factor: 8.086
Publication type: Letter or abstract
Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al.
DOI: 10.1111/ajt.16855

Inhaled Corticosteroid Use Among COPD Patients in Primary Care in Spain.

PMID: 35115771
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2022
Reference: Int J Chron Obstruct Pulmon Dis. 2022 Jan 25;17:245-258. doi: 10.2147/COPD.S342220. eCollection 2022.
Impact factor: 3.355
Publication type: Paper in international publication
Authors: Miravitlles, Marc; Roman-Rodriguez, Miguel; Ribera, Xavier; Ritz, John; Izquierdo, Jose Luis et al.
DOI: 10.2147/COPD.S342220

A comprehensive assessment of long-term SARS-CoV-2-specific adaptive immune memory in convalescent COVID-19 Solid Organ Transplant recipients.

PMID: 35124011
Journal: KIDNEY INTERNATIONAL
Year: 2022
Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4.
Impact factor: 10.612
Publication type: Paper in international publication
Authors: Fava, Alexandre; Donadeu, Laura; Jouve, Thomas; Gonzalez-Costello, Jose; Llado, Laura; Santana, Carolina; Toapanta, Nestor; Lopez, Manuel; Pernin, Vincent; Facundo, Carme et al.
DOI: 10.1016/j.kint.2021.12.029

Pilot Trial of Extended Hypothermic Lung Preservation to Analyze Ischemia-reperfusion Injury in Pigs.

PMID: 33849720
Journal:
Year: 2021
Reference: Arch Bronconeumol (Engl Ed). 2021 Mar 18:S0300-2896(21)00106-X. doi: 10.1016/j.arbres.2021.03.008.
Impact factor:
Publication type: Paper in international publication
Authors: Barrecheguren, Miriam; Boada-Perez, Meritxell; Boldo, Alba; Esquinas, Cristina; Fraile, Carlos; Gatius-Caldero, Sonia; Gomez-Olles, Susana; Milla-Collado, Lucia; Ojanguren, Amaia; Ojanguren, Inigo et al.
DOI: 10.1016/j.arbres.2021.03.008

Prediction Equations for Maximal Aerobic Capacity on Cycle Ergometer for the Spanish Adult Population.

PMID: 35698953
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Jul;57(7):471-478. doi: 10.1016/j.arbr.2020.09.011.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Garcia-Rio, Francisco, Gea, Joaquim, Rodriguez-Chiaradia, Diego A, Burgos, Felip, Munoz, Xavier, Puente-Maestu, Luis, Blanco, Isabel, Ojanguren, Inigo, Galdiz, Batxi, Gomez-Seco, Julio et al.
DOI: 10.1016/j.arbr.2020.09.011

Predictive Value of Immune Cell Functional Assay for Non-Cytomegalovirus Infection in Lung Transplant Recipients: A Multicenter Prospective Observational Study.

PMID: 35699006
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):690-696. doi: 10.1016/j.arbr.2020.12.012.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Rosado, Silvia, Alonso, Rodrigo, Berastegui, Cristina, Arcos, Ibai Los, Redel, Javier, Marcos, Pedro J, Cifrian, Jose Manuel, Sole, Amparo, Laporta, Rosalia, Sintes, Helena et al.
DOI: 10.1016/j.arbr.2020.12.012

Long-term Follow-up in Adult Patients with Cystic Fibrosis and Deep Intronic Splicing Variants.

PMID: 35698963
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Jul;57(7):501-503. doi: 10.1016/j.arbr.2020.11.017.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Polverino, Eva, Culebras, Mario, Clofent, David, Garcia Arumi, Elena, Tizzano, Eduardo F, de Gracia, Javier, Gartner, Silvia, Fernandez-Alvarez, Paula, Alvarez, Antonio, Loor, Karina et al.
DOI: 10.1016/j.arbr.2020.11.017

Customized Massive Parallel Sequencing Panel for Diagnosis of Pulmonary Arterial Hypertension.

PMID: 33007923
Journal: Genes
Year: 2020
Reference: Genes (Basel). 2020 Sep 30;11(10). pii: genes11101158. doi: 10.3390/genes11101158.
Impact factor: 3.759
Publication type: Paper in international publication
Authors: Castano, Jair Antonio Tenorio, Hernandez-Gonzalez, Ignacio, Gallego, Natalia, Perez-Olivares, Carmen, Ochoa Parra, Nuria, Arias, Pedro, Granda, Elena, Acebo, Gonzalo Gomez, Lago-Docampo, Mauro, Palomino-Doza, Julian et al.
DOI: 10.3390/genes11101158

Impact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey.

PMID: 32843180
Journal: RESPIRATORY MEDICINE
Year: 2020
Reference: Respir Med. 2020 Aug - Sep;170:106062. doi: 10.1016/j.rmed.2020.106062. Epub 2020 Jun 8.
Impact factor: 3.095
Publication type: Paper in international publication
Authors: Gomez-Bonilla, Ainhoa, Diab-Caceres, Layla, Prados-Sanchez, Concepcion, Alvarez-Fernandez, Antonio, Garcia-Marcos, Patricia W, Penalver-Mellado, Carlos, Pastor-Vivero, M Dolores, Olveira, Casilda, Lopez-Neyra, Alejandro, Castillo-Corullon, Silvia et al.
DOI: 10.1016/j.rmed.2020.106062

New opacities in lung allograft after transbronchial cryobiopsy.

PMID: 32843174
Journal: RESPIRATORY MEDICINE
Year: 2020
Reference: Respir Med. 2020 Aug - Sep;170:106043. doi: 10.1016/j.rmed.2020.106043. Epub 2020 May 25.
Impact factor: 3.095
Publication type: Paper in international publication
Authors: Loor, Karina, Pallisa, Esther, Culebras, Mario, Deu, Maria, Alvarez, Antonio, Sansano, Irene, Berastegui, Cristina, Clofent, David, Polverino, Eva, de Gracia, Javier et al.
DOI: 10.1016/j.rmed.2020.106043

Clinical and spirometric variables are better predictors of COPD exacerbations than routine blood biomarkers.

PMID: 32829181
Journal: RESPIRATORY MEDICINE
Year: 2020
Reference: Respir Med. 2020 Sep;171:106091. doi: 10.1016/j.rmed.2020.106091. Epub 2020 Aug 5.
Impact factor: 3.095
Publication type: Paper in international publication
Authors: Nunez, Alexa, Marras, Viviana, Harlander, Matevz, Mekov, Evgeni, Turel, Matjaz, Petkov, Rossen, Lestan, David, Yanev, Nikolay, Negri, Silvia, Barrecheguren, Miriam et al.
DOI: 10.1016/j.rmed.2020.106091

Real-life experience of inhaled iloprost for patients with pulmonary arterial hypertension: Insights from the Spanish REHAP registry.

PMID: 30316648
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2019
Reference: Int J Cardiol. 2019 Jan 15;275:158-164. doi: 10.1016/j.ijcard.2018.10.012. Epub 2018 Oct 5.
Impact factor: 3.471
Publication type: Paper in international publication
Authors: Del Pozo, Roberto, Blanco, Isabel, Hernandez-Gonzalez, Ignacio, Lopez-Meseguer, Manuel, Lopez-Reyes, Raquel, Lazaro-Salvador, Maria, Elias-Hernandez, Teresa, Alvarez-Vega, Pablo, Perez-Penate, Gregorio Miguel, Martinez-Menaca, Amaya et al.
DOI: 10.1016/j.ijcard.2018.10.012

Diesel exhausts particles: Their role in increasing the incidence of asthma. Reviewing the evidence of a causal link.

PMID: 30586799
Journal: SCIENCE OF THE TOTAL ENVIRONMENT
Year: 2019
Reference: Sci Total Environ. 2019 Feb 20;652:1129-1138. doi: 10.1016/j.scitotenv.2018.10.188. Epub 2018 Oct 15.
Impact factor: 5.589
Publication type: Paper in international publication
Authors: Munoz, X, Barreiro, E, Bustamante, V, Lopez-Campos, J L, Gonzalez-Barcala, F J, Cruz, M J et al.
DOI: 10.1016/j.scitotenv.2018.10.188

Bronchiectasis in severe asthma: a distinct phenotype?

PMID: 30461531
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2019
Reference: Curr Opin Pulm Med. 2019 Jan;25(1):71-78. doi: 10.1097/MCP.0000000000000542.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Perez-Miranda, Javier, Traversi, Letizia, Polverino, Eva et al.
DOI: 10.1097/MCP.0000000000000542

EXPRESS: Proximal pulmonary arterial wall disease in patients with persistent pulmonary hypertension after successful left-sided valve replacement according to the hemodynamic phenotype.

PMID: 30430894
Journal: Pulmonary Circulation
Year: 2019
Reference: Pulm Circ. 2019 Jan-Mar;9(1):2045894018816972. doi: 10.1177/2045894018816972. Epub 2018 Nov 15.
Impact factor: 2.075
Publication type: Paper in international publication
Authors: Domingo, Enric, Grignola, Juan, Trujillo, Pedro, Aguilar, Rio, Roman, Antonio et al.
DOI: 10.1177/2045894018816972

Duration of the efficacy of omalizumab after treatment discontinuation in 'real life' severe asthma.

PMID: 29079610
Journal: THORAX
Year: 2018
Reference: Thorax. 2018 Aug;73(8):782-784. doi: 10.1136/thoraxjnl-2017-210017. Epub 2017 Oct 27.
Impact factor: 9.655
Publication type: Letter or abstract
Authors: Vennera, Maria Del Carmen, Sabadell, Carlos, Picado, Cesar, Alvarez Puebla, M J, Irigaray, R, Martinez-Moragon, E, Pellicer, C, Martinez, C, Munoz, X, Canete, C et al.
DOI: 10.1136/thoraxjnl-2017-210017

Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire.

PMID: 30538445
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2018
Reference: Int J Chron Obstruct Pulmon Dis. 2018 Nov 26;13:3837-3844. doi: 10.2147/COPD.S179402. eCollection 2018.
Impact factor: 2.917
Publication type: Paper in international publication
Authors: Nunez, Alexa, Esquinas, Cristina, Barrecheguren, Miriam, Calle, Myriam, Casamor, Ricard, Miravitlles, Marc et al.
DOI: 10.2147/COPD.S179402

Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness.

PMID: 30145946
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 Sep 20;379(12):1118-1127. doi: 10.1056/NEJMoa1805090. Epub 2018 Aug 26.
Impact factor: 79.258
Publication type: Paper in international publication
Authors: Weitz, Jeffrey I, Spyropoulos, Alex C, Ageno, Walter, Albers, Gregory W, Elliott, C Gregory, Halperin, Jonathan L, Hiatt, William R, Maynard, Gregory A, Steg, P Gabriel, Maslianski, Boris et al.
DOI: 10.1056/NEJMoa1805090

Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson's Disease: A Pilot Study.

PMID: 30515291
Journal: Parkinsons Disease
Year: 2018
Reference: Parkinsons Dis. 2018 Nov 1;2018:8691495. doi: 10.1155/2018/8691495. eCollection 2018.
Impact factor: 2.117
Publication type: Paper in international publication
Authors: De Fabregues, Oriol, Ferre, Alex, Romero, Odile, Quintana, Manuel, Alvarez-Sabin, Jose et al.
DOI: 10.1155/2018/8691495

Epidemiology and Risk Factors for Cancer After Lung Transplantation.

PMID: 29198662
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2285-2291. doi: 10.1016/j.transproceed.2017.09.043.
Impact factor: 0.908
Publication type: Paper in international publication
Authors: Berastegui, C, LaPorta, R, Lopez-Meseguer, M, Romero, L, Gomez-Olles, S, Riera, J, Monforte, V, Saez, B, Bravo, C, Roman, A et al.
DOI: 10.1016/j.transproceed.2017.09.043

BANFF-CATALAN TRANSPLANTATION SOCIETY JOINT SCIENTIFIC MEETING Preface Foreword

PMID: 29198651
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2239. doi: 10.1016/j.transproceed.2017.10.012.
Impact factor: 0.908
Publication type: Letter or abstract
Authors: Roman, Antonio, Solez, Kim, Mengel, Michael, Seron, Daniel et al.
DOI: 10.1016/j.transproceed.2017.10.012

Lung and heart-lung transplantation in pulmonary arterial hypertension.

PMID: 29161284
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Nov 21;12(11):e0187811. doi: 10.1371/journal.pone.0187811. eCollection 2017.
Impact factor: 2.806
Publication type: Paper in international publication
Authors: Lopez-Meseguer, Manuel, Quezada, Carlos A, Ramon, Maria A, Lazaro, Maria, Dos, Laura, Lara, Antonio, Lopez, Raquel, Blanco, Isabel, Roman, Antonio, Escribano, Pilar et al.
DOI: 10.1371/journal.pone.0187811

Continuous positive airway pressure improves sleep quality, but not glycaemic control, in patients with poorly controlled long-standing type 2 diabetes.

PMID: 29029945
Journal: DIABETES & METABOLISM
Year: 2017
Reference: Diabetes Metab. 2017 Dec;43(6):547-549. doi: 10.1016/j.diabet.2017.08.006. Epub 2017 Oct 10.
Impact factor: 4.101
Publication type: Letter or abstract
Authors: Torrella, M, Castells, I, Gimenez-Perez, G, Miquel, M, Simo, O, Barbeta, E, Sampol, G, Recasens, A et al.
DOI: 10.1016/j.diabet.2017.08.006

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.