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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Challenges for asthma units in response to COVID-19: a qualitative group dynamics analysis.

PMID: 33882776
Journal: JOURNAL OF ASTHMA
Year: 2022
Reference: J Asthma. 2022 Jun;59(6):1195-1202. doi: 10.1080/02770903.2021.1917605. Epub 2021 May 8.
Impact factor: 2.515
Publication type: Paper in international publication
Authors: Martinez Rivera, Carlos, Crespo-Lessman, Astrid, Arismendi, Ebymar, Munoz-Esquerre, Mariana, Ausin, Pilar, Bobolea, Irina, Dalmau Duch, Gaspar, Pifarre Teixido, Ricardo, Sabater Talaverano, Gladis, Sogo Sabardia, Ana et al.
DOI: 10.1080/02770903.2021.1917605

Effectiveness of Treatment With Dual Bronchodilation (LABA/LAMA) Compared With Combination Therapy (LABA/ICS) for Patients With COPD: A Population-Based Study.

PMID: 35618580
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 May 13. pii: S0300-2896(22)00337-4. doi: 10.1016/j.arbres.2022.05.002.
Impact factor: 4.872
Publication type: Paper in national publication
Authors: Monteagudo, Monica, Nunez, Alexa, Barrecheguren, Miriam, Miravitlles, Marc et al.
DOI: 10.1016/j.arbres.2022.05.002

Why Use Aprepitant Only as a Cough Suppressant in Lung Cancer When at Higher Doses it Could Also Exert an Antitumor Action?

PMID: 35606264
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 May 13. pii: S0300-2896(22)00339-8. doi: 10.1016/j.arbres.2022.05.004.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Munoz, Miguel, Munoz, Miguel E, Morell, Ferran, Covenas, Rafael et al.
DOI: 10.1016/j.arbres.2022.05.004

Tuberculosis Reactivation After Severe SARS-COV-2 Pneumonia.

PMID: 35550308
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 Apr 27. pii: S0300-2896(22)00323-4. doi: 10.1016/j.arbres.2022.03.024.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: De Souza-Galvao, Maria-Luiza, Jimenez-Fuentes, Maria-Angeles, Cardoso-Landivar, Jose et al.
DOI: 10.1016/j.arbres.2022.03.024

Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.

PMID: 34378323
Journal: EMBO Molecular Medicine
Year: 2021
Reference: EMBO Mol Med. 2021 Sep 7;13(9):e13929. doi: 10.15252/emmm.202113929. Epub 2021 Aug 11.
Impact factor: 12.137
Publication type: Paper in international publication
Authors: Miller, Suzanne, Garcia, Nadia, Capellades, Jordi, Gomez, Antonio, Vidal, August, Palomero, Luis, Espin, Roderic, Extremera, Ana I, Blommaert, Eline, Revilla-Lopez, Eva et al.
DOI: 10.15252/emmm.202113929

Circulating Cell Biomarkers in Pulmonary Arterial Hypertension: Relationship with Clinical Heterogeneity and Therapeutic Response.

PMID: 34359858
Journal: Cells
Year: 2021
Reference: Cells. 2021 Jul 4;10(7). pii: cells10071688. doi: 10.3390/cells10071688.
Impact factor: 6.6
Publication type: Paper in international publication
Authors: Barbera, Joan Albert, Peinado, Victor I, Blanco, Isabel, Garcia-Lucio, Jessica, Del Pozo, Roberto, Garcia, Agustin Roberto, Ferrer, Elisabet, Crespo, Isabel, Rodriguez-Chiaradia, Diego A, Simeon-Aznar, Carmen Pilar et al.
DOI: 10.3390/cells10071688

CMV-specific Cell-Mediated Immunity Predicts High level of CMV Replication after Prophylaxis withdrawal in Lung Transplant Recipients.

PMID: 33245359
Journal: JOURNAL OF INFECTIOUS DISEASES
Year: 2021
Reference: J Infect Dis. 2021 Aug 2;224(3):526-531. doi: 10.1093/infdis/jiaa727.
Impact factor: 5.226
Publication type: Paper in international publication
Authors: Revilla-Lopez, Eva, Jarque, Marta, Crespo, Elena, Torija, Alba, Bravo, Carles, Los Arcos, Ibai, Meneghini, Maria, Fava, Alex, Roman, Antonio, Monforte, Victor et al.
DOI: 10.1093/infdis/jiaa727

Impact of baseline patient characteristics on dupilumab efficacy in type 2 asthma.

PMID: 34326187
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2021
Reference: Eur Respir J. 2021 Oct 7;58(4). pii: 13993003.04605-2020. doi: 10.1183/13993003.04605-2020. Print 2021 Oct.
Impact factor: 16.671
Publication type: Letter or abstract
Authors: Busse, William W, Paggiaro, Pierluigi, Munoz, Xavier, Casale, Thomas B, Castro, Mario, Canonica, G Walter, Douglass, Jo A, Tohda, Yuji, Daizadeh, Nadia, Ortiz, Benjamin et al.
DOI: 10.1183/13993003.04605-2020

Lung Transplant in HIV-Infected Patients. Single Centre Experience.

PMID: 32466038
Journal: JOURNAL OF HEART AND LUNG TRANSPLANTATION
Year: 2020
Reference: J Heart Lung Transplant. 2020 Apr;39(4S):S81-S82. doi: 10.1016/j.healun.2020.01.1306. Epub 2020 Mar 30.
Impact factor: 7.865
Publication type: Paper in international publication
Authors: Arjona Peris, M, Revilla Lopez, E, Berastegui, C, Saez Gimenez, B, Barrecheguren, M, Bravo, C, Monforte, V, Bello, I, Sacanell, J, Burgos, J et al.
DOI: 10.1016/j.healun.2020.01.1306

Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases.

PMID: 32457198
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2020
Reference: Eur Respir J. 2020 Jul 9;56(1). pii: 13993003.01398-2020. doi: 10.1183/13993003.01398-2020. Print 2020 Jul.
Impact factor: 12.339
Publication type: Letter whit IF
Authors: Borisov, Sergey, Alffenaar, Jan-Willem, Andrejak, Claire, Bachez, Pierre, Bart, Pierre-Alexandre, Belilovski, Evgeny, Cardoso-Landivar, Jose, Centis, Rosella, D'Ambrosio, Lia, De Souza-Galvao, Maria-Luiza et al.
DOI: 10.1183/13993003.01398-2020

Analysis of Blood Biomarkers in Patients with Chronic Obstructive Pulmonary Disease (COPD) and with Asthma-COPD Overlap (ACO).

PMID: 32380914
Journal: COPD-Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: COPD. 2020 Jun;17(3):306-310. doi: 10.1080/15412555.2020.1761314. Epub 2020 May 7.
Impact factor: 2.5
Publication type: Paper in international publication
Authors: Barrecheguren, Miriam, Gava, Giordana, Nunez, Alexa, Esquinas, Cristina, Sarasate, Mikel, Loeb, Eduardo, Pirina, Pietro, Miravitlles, Marc et al.
DOI: 10.1080/15412555.2020.1761314

Long-term Noninvasive Ventilation in Obesity Hypoventilation Syndrome without Severe Obstructive Sleep Apnea.

PMID: 32343963
Journal: CHEST
Year: 2020
Reference: Chest. 2020 Sep;158(3):1176-1186. doi: 10.1016/j.chest.2020.03.068. Epub 2020 Apr 25.
Impact factor: 8.308
Publication type: Paper in international publication
Authors: Egea, Carlos, Barca, Javier, Vazquez-Polo, Francisco J, Negrin, Miguel A, Martel-Escobar, Maria, Barbe, Ferran, Mokhlesi, Babak, Riesco, Juan A, Gonzalez-Mangado, Nicolas, Troncoso, Maria F et al.
DOI: 10.1016/j.chest.2020.03.068

PHARMACOKINETIC STUDY OF CONVERSION BETWEEN TWO FORMULATIONS OF ONCE-DAILY EXTENDED-RELEASE TACROLIMUS IN STABLE LUNG TRANSPLANT PATIENTS.

PMID: 29965950
Journal: TRANSPLANTATION
Year: 2018
Reference: Transplantation. 2018 Oct;102(10):e439-e446. doi: 10.1097/TP.0000000000002348.
Impact factor: 3.96
Publication type: Paper in international publication
Authors: Roman, Antonio, Vima, Jaume, Sintes, Helena, Saez-Gimenez, Berta, Berastegui, Cristina, Lopez-Meseguer, Manuel, Monforte, Victor, Bravo, Carlos, Gomez-Olles, Susana et al.
DOI: 10.1097/TP.0000000000002348

Mandibular advancement devices in the treatment of obstructive sleep apnea. A necessary and effective option.

PMID: 29287937
Journal: MEDICINA CLINICA
Year: 2018
Reference: Med Clin (Barc). 2018 Jul 13;151(1):34-38. doi: 10.1016/j.medcli.2017.11.026. Epub 2017 Dec 27.
Impact factor: 1.168
Publication type: Paper in national publication
Authors: Sampol Rubio, Gabriel, Macias Escalada, Emilio, Montserrat Canal, Josep Maria, Teran Santos, Joaquin et al.
DOI: 10.1016/j.medcli.2017.11.026

Diagnosis of alpha1-antitrypsin deficiency not just in severe COPD.

PMID: 29921528
Journal: Pulmonology
Year: 2018
Reference: Pulmonology. 2018 Nov - Dec;24(6):351-353. doi: 10.1016/j.pulmoe.2018.05.005. Epub 2018 Jun 18.
Impact factor: 0
Publication type: Paper in international publication
Authors: Nunez, A, Barrecheguren, M, Rodriguez, E, Miravitlles, M, Esquinas, C et al.
DOI: 10.1016/j.pulmoe.2018.05.005

Current controversies in the stepping up and stepping down of inhaled therapies for COPD at the patient level.

PMID: 29924458
Journal: RESPIROLOGY
Year: 2018
Reference: Respirology. 2018 Sep;23(9):818-27. doi: 10.1111/resp.13341.
Impact factor: 4.407
Publication type: Review in national publication
Authors: Barreiro, Esther, Munoz, Xavier, Lopez-Campos, Jose Luis, Carrasco Hernandez, Laura, Bustamante, Victor et al.
DOI: 10.1111/resp.13341

Effects of diesel exhaust particle exposure on a murine model of asthma due to soybean.

PMID: 28628664
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Jun 19;12(6):e0179569. doi: 10.1371/journal.pone.0179569. eCollection 2017.
Impact factor: 2.806
Publication type: Paper in international publication
Authors: Alvarez-Simon, Daniel, Gomez-Olles, Susana, de Homdedeu, Miquel, Untoria, Maria-Dolores, Cruz, Maria-Jesus, Munoz, Xavier et al.
DOI: 10.1371/journal.pone.0179569

High sensitivity and negative predictive value of the DETECT algorithm for an early diagnosis of pulmonary arterial hypertension in systemic sclerosis: application in a single center.

PMID: 28615037
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2017
Reference: Arthritis Res Ther. 2017 Jun 14;19(1):135. doi: 10.1186/s13075-017-1327-8.
Impact factor: 4.121
Publication type: Paper in international publication
Authors: Guillen-Del Castillo, Alfredo, Callejas-Moraga, Eduardo L, Garcia, Gabriela, Rodriguez-Palomares, Jose F, Roman, Antonio, Berastegui, Cristina, Lopez-Meseguer, Manuel, Domingo, Enric, Fonollosa-Pla, Vicente, Simeon-Aznar, Carmen Pilar et al.
DOI: 10.1186/s13075-017-1327-8

Prognostic Role of Exhaled Breath Condensate pH and Fraction Exhaled Nitric Oxide in Systemic Sclerosis Related Interstitial Lung Disease.

PMID: 28038794
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Mar;53(3):120-127. doi: 10.1016/j.arbres.2016.09.014. Epub 2016 Dec 27.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Guillen-Del Castillo, Alfredo, Sanchez-Vidaurre, Sara, Simeon-Aznar, Carmen P, Cruz, Maria J, Fonollosa-Pla, Vicente, Munoz, Xavier et al.
DOI: 10.1016/j.arbres.2016.09.014

Non-IgE-Mediated Asthma after Zinc Exposure.

PMID: 27818026
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Jun;53(6):346-347. doi: 10.1016/j.arbres.2016.09.009. Epub 2016 Nov 3.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Leal, Angelica, Caselles, Irene, Rodriguez-Bayarri, Maria Jesus, Munoz, Xavier et al.
DOI: 10.1016/j.arbres.2016.09.009

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.