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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Is There an Association Between Nocturia and Nighttime Hypertension in Patients With Moderate to Severe Sleep Apnea?

PMID: 35312559
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 Apr;58(4):369-371. doi: 10.1016/j.arbres.2021.09.014. Epub 2021 Oct 12.
Impact factor: 4.872
Publication type: Letter whit IF
Authors: Lloberes, Patricia, Silveira, Maria Guadalupe, Sampol, Julia, Esquinas, Cristina, Espinel, Eugenia, Ferrer, Roser, Gonzalo, Marta, Sampol, Gabriel et al.
DOI: 10.1016/j.arbres.2021.09.014

An open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single doses of GSK2586881 in participants with pulmonary arterial hypertension.

PMID: 35506108
Journal: Pulmonary Circulation
Year: 2022
Reference: Pulm Circ. 2022 Jan 20;12(1):e12024. doi: 10.1002/pul2.12024. eCollection 2022 Jan.
Impact factor: 3.017
Publication type: Paper in international publication
Authors: Simon, Marc A, Hanrott, Kate, Budd, David C, Torres, Fernando, Grunig, Ekkehard, Escribano-Subias, Pilar, Meseguer, Manuel L, Halank, Michael, Opitz, Christian, Hall, David A et al.
DOI: 10.1002/pul2.12024

Exacerbations among patients with asthma are largely dependent on the presence of multimorbidity.

PMID: 35503227
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Investig Allergol Clin Immunol. 2022 May 2:0. doi: 10.18176/jiaci.0816.
Impact factor: 7.033
Publication type: Paper in international publication
Authors: Dominguez-Ortega, J, Luna-Porta, J A, Olaguibel, J M, Barranco, E, Arismendi, E, Barroso, B, Betancor, D, Bobolea, I, Caballero, M L, Cardaba, B et al.
DOI: 10.18176/jiaci.0816

The Effect of Borderline Pulmonary Hypertension on Survival in Chronic Lung Disease.

PMID: 35462365
Journal: RESPIRATION
Year: 2022
Reference: Respiration. 2022 Apr 22:1-11. doi: 10.1159/000524263.
Impact factor: 3.58
Publication type: Paper in international publication
Authors: Piccari, Lucilla, Wort, Stephen John, Meloni, Federica, Rizzo, Monica, Price, Laura C, Martino, Lavinia, Salvaterra, Elena, Scelsi, Laura, Lopez Meseguer, Manuel, Blanco, Isabel et al.
DOI: 10.1159/000524263

Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue.

PMID: 34312290
Journal: MOLECULAR CANCER RESEARCH
Year: 2021
Reference: Mol Cancer Res. 2021 Nov;19(11):1840-1853. doi: 10.1158/1541-7786.MCR-21-0220. Epub 2021 Jul 26.
Impact factor: 5.852
Publication type: Paper in international publication
Authors: Blommaert, Eline, Herranz, Carmen, Roman, Antonio, Saez, Berta, Ancochea, Julio, Valenzuela, Claudia, Ussetti, Piedad, Laporta, Rosalia, Rodriguez-Portal, Jose A, van Moorsel, Coline H M et al.
DOI: 10.1158/1541-7786.MCR-21-0220

Variability of blood eosinophil count and prognosis of COPD exacerbations.

PMID: 34269633
Journal: ANNALS OF MEDICINE
Year: 2021
Reference: Ann Med. 2021 Dec;53(1):1152-1158. doi: 10.1080/07853890.2021.1949489.
Impact factor: 4.709
Publication type: Paper in international publication
Authors: Martinez-Gestoso, Sandra, Garcia-Sanz, Maria-Teresa, Calvo-Alvarez, Uxio, Doval-Oubina, Liliana, Camba-Matos, Sandra, Salgado, Francisco-Javier, Munoz, Xavier, Perez-Lopez-Corona, Purificacion, Gonzalez-Barcala, Francisco-Javier et al.
DOI: 10.1080/07853890.2021.1949489

COVID-19 in Solid Organ Transplant Recipients in Spain Throughout 2020: Catching the Wave?

PMID: 34241988
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Oct 1;105(10):2146-2155. doi: 10.1097/TP.0000000000003873.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Molina, Maria, Vazquez-Sanchez, Teresa, Crespo, Marta, Facundo, Carme, Rodriguez-Ferrero, M feminine Luisa, Ruiz Fuentes, M feminine Carmen, Loinaz, Carmelo, Bernal, Gabriel, Melilli, Edoardo, Bravo, Carlos et al.
DOI: 10.1097/TP.0000000000003873

Systematic review on long-term adverse effects of inhaled corticosteroids in the treatment of COPD.

PMID: 34168063
Journal: European Respiratory Review
Year: 2021
Reference: Eur Respir Rev. 2021 Jun 23;30(160). pii: 30/160/210075. doi: 10.1183/16000617.0075-2021. Print 2021 Jun 30.
Impact factor: 8.839
Publication type: Review in international publication
Authors: Nunez, Alexa, Urrutia, Gerard, Mohammed, Jibril, Vazquez-Niebla, Juan Carlos, Monteagudo, Monica, Auladell-Rispau, Ariadna, Miravitlles, Marc et al.
DOI: 10.1183/16000617.0075-2021

Effects of the extracorporeal membrane oxygenation circuit on plasma levels of ceftolozane.

PMID: 31387460
Journal: PERFUSION-UK
Year: 2020
Reference: Perfusion. 2020 Apr;35(3):267-270. doi: 10.1177/0267659119864813. Epub 2019 Aug 7.
Impact factor: 1.234
Publication type: Paper in international publication
Authors: Argudo, Eduard, Riera, Jordi, Luque, Sonia, Los-Arcos, Ibai, Lopez-Meseguer, Manuel, Sandiumenge, Alberto, Nuvials, Xavier, Grau, Santiago, Ferrer, Ricard et al.
DOI: 10.1177/0267659119864813

Screening for Latent Tuberculosis and Biological Therapy.

PMID: 31128848
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Mar;56(3):139-140. doi: 10.1016/j.arbres.2019.04.008. Epub 2019 May 22.
Impact factor: 4.957
Publication type: Editorial in national publication
Authors: de Souza-Galvao, Maria Luiza, Jimenez-Fuentes, Maria Angeles et al.
DOI: 10.1016/j.arbres.2019.04.008

Non-Malignant Obstruction of the Upper Airway: A Rare Case of Tracheal Amyloidosis.

PMID: 31128847
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Apr;56(4):252. doi: 10.1016/j.arbres.2019.03.030. Epub 2019 May 23.
Impact factor: 4.957
Publication type: Paper in national publication
Authors: Felipe Montiel, Almudena, Loor Reyes, Karina, Culebras Amigo, Mario et al.
DOI: 10.1016/j.arbres.2019.03.030

Association Between Routine Blood Biomarkers and Clinical Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease.

PMID: 32280207
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: Int J Chron Obstruct Pulmon Dis. 2020 Mar 31;15:681-690. doi: 10.2147/COPD.S240720. eCollection 2020.
Impact factor: 2.772
Publication type: Paper in international publication
Authors: Nunez, Alexa, Marras, Viviana, Harlander, Matevz, Mekov, Evgeni, Esquinas, Cristina, Turel, Matjaz, Lestan, David, Petkov, Rosen, Yanev, Nikolay, Pirina, Pietro et al.
DOI: 10.2147/COPD.S240720

Sleep-disordered breathing, circulating exosomes, and insulin sensitivity in adipocytes.

PMID: 29892042
Journal: INTERNATIONAL JOURNAL OF OBESITY
Year: 2018
Reference: Int J Obes (Lond). 2018 Jun;42(6):1127-1139. doi: 10.1038/s41366-018-0099-9. Epub 2018 Jun 11.
Impact factor: 5.151
Publication type: Paper in international publication
Authors: de Terreros, Francisco J Gomez, Khalyfa, Abdelnaby, Gozal, David, Masa, Juan F, Marin, Jose Maria, Qiao, Zhuanghong, Corral, Jaime, Gonzalez, Monica, Marti, Sergi, Kheirandish-Gozal, Leila et al.
DOI: 10.1038/s41366-018-0099-9

Impact of Hypertonic Saline Solutions on Sputum Expectoration and Their Safety Profile in Patients with Bronchiectasis: A Randomized Crossover Trial.

PMID: 29878856
Journal: Journal of Aerosol Medicine and Pulmonary Drug Delivery
Year: 2018
Reference: J Aerosol Med Pulm Drug Deliv. 2018 Oct;31(5):281-289. doi: 10.1089/jamp.2017.1443. Epub 2018 Jun 7.
Impact factor: 2.927
Publication type: Paper in international publication
Authors: Herrero-Cortina, Beatriz, Alcaraz, Victoria, Vilaro, Jordi, Torres, Antoni, Polverino, Eva et al.
DOI: 10.1089/jamp.2017.1443

Clinical characteristics and outcome of lung transplant recipients with respiratory isolation of Corynebacterium spp.

PMID: 29793964
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2018
Reference: J Clin Microbiol. 2018 Jul 26;56(8). pii: JCM.00142-18. doi: 10.1128/JCM.00142-18. Print 2018 Aug.
Impact factor: 4.054
Publication type: Paper in international publication
Authors: Len, Oscar, Teresa Martin-Gomez, Maria, Baroja, Aida, Berastegui, Cristina, Deu, Maria, Sacanell, Judith, Roman, Antonio, Gavalda, Joan, Los-Arcos, Ibai et al.
DOI: 10.1128/JCM.00142-18

The role of transbronchial cryobiopsy in lung transplantation.

PMID: 29779238
Journal: HISTOPATHOLOGY
Year: 2018
Reference: Histopathology. 2018 Oct;73(4):593-600. doi: 10.1111/his.13656. Epub 2018 Jul 5.
Impact factor: 3.267
Publication type: Paper in international publication
Authors: Montero, M Angeles, de Gracia, Javier, Culebras, Mario, Mugnier, Jacqueline, Alvarez, Antonio, Berastegui, Cristina, Ortiz-Villalon, Cristian et al.
DOI: 10.1111/his.13656

BALF cytokines in different phenotypes of chronic lung allograft dysfunction in lung transplant patients.

PMID: 28008659
Journal: CLINICAL TRANSPLANTATION
Year: 2017
Reference: Clin Transplant. 2017 Mar;31(3). doi: 10.1111/ctr.12898. Epub 2017 Jan 27.
Impact factor: 1.865
Publication type: Paper in international publication
Authors: Berastegui, Cristina, Gomez-Olles, Susana, Sanchez-Vidaurre, Sara, Culebras, Mario, Monforte, Victor, Lopez-Meseguer, Manuel, Bravo, Carlos, Ramon, Maria-Antonia, Romero, Laura, Sole, Joan et al.
DOI: 10.1111/ctr.12898

Utility of Bronchoalveolar Lavage for the Diagnosis of Asbestos-Related Diseases.

PMID: 27914752
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Jun;53(6):318-323. doi: 10.1016/j.arbres.2016.08.016. Epub 2016 Nov 30.
Impact factor: 2.979
Publication type: Paper in national publication
Authors: Cruz, Maria Jesus, Curull, Victor, Pijuan, Lara, Alvarez-Simon, Daniel, Sanchez-Font, Albert, de Gracia, Javier, Culebras, Mario, Ferrer, Jaume et al.
DOI: 10.1016/j.arbres.2016.08.016

Hypersensitivity Pneumonitis: Perspectives in Diagnosis and Management.

PMID: 28598197
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2017
Reference: Am J Respir Crit Care Med. 2017 Sep 15;196(6):680-689. doi: 10.1164/rccm.201611-2201PP.
Impact factor: 13.204
Publication type: Paper in international publication
Authors: Vasakova, Martina, Morell, Ferran, Walsh, Simon, Leslie, Kevin, Raghu, Ganesh et al.
DOI: 10.1164/rccm.201611-2201PP

Epidemiology and Immediate Indirect Effects of Respiratory Viruses in Lung Transplant Recipients: A 5-Year Prospective Study.

PMID: 27615811
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2017
Reference: Am J Transplant. 2017 May;17(5):1304-1312. doi: 10.1111/ajt.14042. Epub 2016 Oct 14.
Impact factor: 6.165
Publication type: Paper in international publication
Authors: Roman, A, Peghin, M, Hirsch, H H, Len, O, Codina, G, Berastegui, C, Saez, B, Sole, J, Cabral, E, Sole, A et al.
DOI: 10.1111/ajt.14042

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.