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Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Right Ventricular Postsystolic Strain Curve Morphology before and after Vasodilator Treatment in Idiopathic Pulmonary Arterial Hypertension.

PMID: 35832825
Journal: CASE (Philadelphia, Pa.)
Year: 2022
Reference: CASE (Phila). 2022 Apr 22;6(5):228-232. doi: 10.1016/j.case.2022.03.005. eCollection 2022 Jul.
Impact factor: 0
Publication type: Letter or abstract
Authors: Mayos-Perez, Mercedes, Meseguer, Manuel Lopez, Podzamczer, Ines, Bos, Lidia, Rodriguez-Perez, Alvaro, Leta, Ruben et al.
DOI: 10.1016/j.case.2022.03.005

Analysis of Exposure and Respiratory Health Effects of Volcanic Eruption in the Canary Islands (ASHES). A SEPAR Study.

PMID: 35811209
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 May 21. pii: S0300-2896(22)00346-5. doi: 10.1016/j.arbres.2022.04.012.
Impact factor: 4.872
Publication type: Letter whit IF
Authors: Ruano-Ravina, Alberto, Acosta, Orlando, Perez, David Diaz, Casanova, Ciro, Velasco, Valle, Llanos, Ana Belen, Peces-Barba, German, Barreiro, Esther, Canas, Ana, Castano, Argelia et al.
DOI: 10.1016/j.arbres.2022.04.012

Plasma exosomes in obesity hypoventilation syndrome patients drive lung cancer cell malignant properties: Effect of long-term adherent CPAP treatment.

PMID: 35811031
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF D
Year: 2022
Reference: Biochim Biophys Acta Mol Basis Dis. 2022 Jul 8;1868(10):166479. doi: 10.1016/j.bbadis.2022.166479.
Impact factor: 5.187
Publication type: Paper in international publication
Authors: Gozal, David, Kheirandish-Gozal, Leila, Khalyfa, Abdelnaby, Masa, Juan F, Qiao, Zhuanhong, Gonzalez, Monica, Marti, Sergi, Khalyfa, Ahamed A et al.
DOI: 10.1016/j.bbadis.2022.166479

Impact of Lung Function Decline on Mortality in Lung Transplant Recipients: Long-Term Results From the L-CsA-i Study for the Prevention of Bronchiolitis Obliterans Syndrome.

PMID: 35721046
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2022 Jun 2;9:897581. doi: 10.3389/fmed.2022.897581. eCollection 2022.
Impact factor: 5.093
Publication type: Paper in international publication
Authors: Voelp, Andreas, Kneidinger, Nikolaus, Ghiani, Alessandro, Milger, Katrin, Monforte, Victor, Knoop, Christiane, Jaksch, Peter, Parmar, Jasvir, Ussetti, Piedad, Sole, Amparo et al.
DOI: 10.3389/fmed.2022.897581

Is there a procoagulant state long-term after lung transplantation? A prospective study.

PMID: 34560353
Journal: RESPIRATORY MEDICINE
Year: 2021
Reference: Respir Med. 2021 Nov;188:106584. doi: 10.1016/j.rmed.2021.106584. Epub 2021 Sep 11.
Impact factor: 3.415
Publication type: Paper in international publication
Authors: Saez-Gimenez, Berta, Clofent, David, Lopez Meseguer, Manuel, Bravo Masgoret, Carlos, Monforte, Victor, Berastegui, Cristina, Revilla-Lopez, Eva, Barrecheguren, Miriam, Arjona-Peris, Marta, Ruiz, Victoria et al.
DOI: 10.1016/j.rmed.2021.106584

Development of a Tool to Measure the Clinical Response to Biologic Therapy in Uncontrolled Severe Asthma: The FEV1, Exacerbations, Oral Corticosteroids, Symptoms Score.

PMID: 33549843
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2021
Reference: J Allergy Clin Immunol Pract. 2021 Jul;9(7):2725-2731. doi: 10.1016/j.jaip.2021.01.033. Epub 2021 Feb 4.
Impact factor: 8.861
Publication type: Paper in international publication
Authors: Crespo, Astrid, Perez de Llano, Luis, Davila, Ignacio, Martinez-Moragon, Eva, Dominguez-Ortega, Javier, Almonacid, Carlos, Colas, Carlos, Garcia-Rivero, Juan Luis, Carmona, Loreto, Garcia de Yebenes, Maria Jesus et al.
DOI: 10.1016/j.jaip.2021.01.033

Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.

PMID: 34437784
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2021
Reference: N Engl J Med. 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665.
Impact factor: 91.253
Publication type: Paper in international publication
Authors: Demeyere, Benedicte, Barry, Peter J, Mall, Marcus A, Alvarez, Antonio, Colombo, Carla, de Winter-de Groot, Karin M, Fajac, Isabelle, McBennett, Kimberly A, McKone, Edward F, Ramsey, Bonnie W et al.
DOI: 10.1056/NEJMoa2100665

Lung Transplant Improves Survival and Quality of Life Regardless of Telomere Dysfunction.

PMID: 34395476
Journal: Frontiers in Medicine
Year: 2021
Reference: Front Med (Lausanne). 2021 Jul 30;8:695919. doi: 10.3389/fmed.2021.695919. eCollection 2021.
Impact factor: 5.093
Publication type: Paper in international publication
Authors: Planas-Cerezales, Lurdes, Arias-Salgado, Elena G, Berastegui, Cristina, Montes-Worboys, Ana, Gonzalez-Montelongo, Rafaela, Lorenzo-Salazar, Jose M, Vicens-Zygmunt, Vanesa, Garcia-Moyano, Marta, Dorca, Jordi, Flores, Carlos et al.
DOI: 10.3389/fmed.2021.695919

Predictors of respiratory complications in patients with C5-T5 spinal cord injuries.

PMID: 32581306
Journal: SPINAL CORD
Year: 2020
Reference: Spinal Cord. 2020 Dec;58(12):1249-1254. doi: 10.1038/s41393-020-0506-7. Epub 2020 Jun 24.
Impact factor: 1.773
Publication type: Paper in international publication
Authors: Sampol, Julia, Gonzalez-Viejo, Miguel Angel, Gomez, Alba, Marti, Sergi, Pallero, Mercedes, Rodriguez, Esther, Launois, Patricia, Sampol, Gabriel, Ferrer, Jaume et al.
DOI: 10.1038/s41393-020-0506-7

Preventing readmissions of COPD patients: more prospective studies are needed.

PMID: 32499307
Journal: European Respiratory Review
Year: 2020
Reference: Eur Respir Rev. 2020 Jun 3;29(156). pii: 29/156/200097. doi: 10.1183/16000617.0097-2020. Print 2020 Jun 30.
Impact factor: 6.22
Publication type: Editorail in international publication
Authors: Nunez, Alexa, Miravitlles, Marc et al.
DOI: 10.1183/16000617.0097-2020

Lung Transplantation Outcomes in Lymphangioleiomyomatosis.

PMID: 32465365
Journal: JOURNAL OF HEART AND LUNG TRANSPLANTATION
Year: 2020
Reference: J Heart Lung Transplant. 2020 Apr;39(4S):S308-S309. doi: 10.1016/j.healun.2020.01.692. Epub 2020 Mar 30.
Impact factor: 7.865
Publication type: Paper in international publication
Authors: Lopez, E Revilla, Gimenez, B Saez, Berastegui, C, Barrecheguren, M, Meseguer, M Lopez, Monforte, V, Olles, S Gomez, Roman, A, Bravo, C et al.
DOI: 10.1016/j.healun.2020.01.692

Acute respiratory failure among lung transplant adults requiring intensive care: Changing spectrum of causative organisms and impact of procalcitonin test in the diagnostic work up.

PMID: 32473604
Journal: Transplant Infectious Disease
Year: 2020
Reference: Transpl Infect Dis. 2020 Oct;22(5):e13346. doi: 10.1111/tid.13346. Epub 2020 Jun 20.
Impact factor: 2.071
Publication type: Paper in international publication
Authors: Tejada, Sofia, Campogiani, Laura, Mazo, Cristopher, Romero, Anabel, Pena, Yolanda, Pont, Teresa, Gomez, Aroa, Roman, Antonio, Rello, Jordi et al.
DOI: 10.1111/tid.13346

Th1-skewed profile and excessive production of proinflammatory cytokines in a NFKB1-deficient patient with CVID and severe gastrointestinal manifestations.

PMID: 30063981
Journal: CLINICAL IMMUNOLOGY
Year: 2018
Reference: Clin Immunol. 2018 Oct;195:49-58. doi: 10.1016/j.clim.2018.07.015. Epub 2018 Jul 29.
Impact factor: 3.557
Publication type: Paper in international publication
Authors: Dieli-Crimi, Romina, Martinez-Gallo, Monica, Franco-Jarava, Clara, Antolin, Maria, Blasco, Laura, Paramonov, Ida, Semidey, Maria E, Fernandez, Antoni Alvarez, Velasquez, Julio, Martin-Nalda, Andrea et al.
DOI: 10.1016/j.clim.2018.07.015

The overlap between bronchiectasis and chronic airways diseases: state of the art and future directions.

PMID: 30049739
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Sep 15;52(3). pii: 13993003.00328-2018. doi: 10.1183/13993003.00328-2018. Print 2018 Sep.
Impact factor: 12.242
Publication type: Review in international publication
Authors: Paggiaro, Pierluigi, Shteinberg, Michal, Aliberti, Stefano, Chalmers, James D, Miravitlles, Marc, Angel Martinez-Garcia, Miguel, Dimakou, Katerina, Polverino, Eva, Hurst, John et al.
DOI: 10.1183/13993003.00328-2018

Addition of hyaluronic acid improves tolerance to 7% hypertonic saline solution in bronchiectasis patients.

PMID: 30014774
Journal: Therapeutic Advances in Respiratory Disease
Year: 2018
Reference: Ther Adv Respir Dis. 2018 Jan-Dec;12:1753466618787385. doi: 10.1177/1753466618787385.
Impact factor: 3.592
Publication type: Paper in international publication
Authors: Maiz, Luis, Giron, Rosa M, Prats, Eva, Clemente, Marta G, Polverino, Eva, Cano, Silvia, Cordovilla, Rosa, Dorca, Jordi, Penalver, Carlos, Baranda, Felix et al.
DOI: 10.1177/1753466618787385

Genetic Variants with Gene Regulatory Effects are Associated with Diisocyanate Asthma.

PMID: 29969634
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2018
Reference: J Allergy Clin Immunol. 2018 Sep;142(3):959-969. doi: 10.1016/j.jaci.2018.06.022. Epub 2018 Jun 30.
Impact factor: 13.258
Publication type: Paper in international publication
Authors: Munoz, Xavier, Quirce, Santiago, Tarlo, Susan, Sastre, Joaquin, Boulet, Louis Philippe, Weirauch, Matthew T, Kaufman, Kenneth, Lemiere, Catherine, Cruz, Maria-Jesus, Miller, Daniel et al.
DOI: 10.1016/j.jaci.2018.06.022

Assessment of the influence of direct tobacco smoke on infection and active TB management.

PMID: 28837570
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Aug 24;12(8):e0182998. doi: 10.1371/journal.pone.0182998. eCollection 2017.
Impact factor: 2.806
Publication type: Paper in international publication
Authors: Latorre, Irene, Altet, Neus, Jimenez-Fuentes, Maria Angeles, Maldonado, Jose, Molina, Israel, Gonzalez-Diaz, Yoel, Mila, Celia, Garcia-Garcia, Esther, Muriel, Beatriz, Villar-Hernandez, Raquel et al.
DOI: 10.1371/journal.pone.0182998

Long-term safety and effectiveness of levodopa-carbidopa intestinal gel infusion.

PMID: 28828219
Journal: Brain and Behavior
Year: 2017
Reference: Brain Behav. 2017 Jul 7;7(8):e00758. doi: 10.1002/brb3.758. eCollection 2017 Aug.
Impact factor: 2.157
Publication type: Paper in international publication
Authors: De Fabregues, Oriol, Dot, Joan, Abu-Suboh, Monder, Hernandez-Vara, Jorge, Ferre, Alex, Romero, Odile, Ibarria, Marta, Seoane, Jose Luis, Raguer, Nuria, Puiggros, Carolina et al.
DOI: 10.1002/brb3.758

Prophylaxis with enoxaparin for prevention of venous thromboembolism after lung transplantation: A retrospective study.

PMID: 28801922
Journal: TRANSPLANT INTERNATIONAL
Year: 2017
Reference: Transpl Int. 2017 Dec;30(12):1266-1274. doi: 10.1111/tri.13021. Epub 2017 Sep 7.
Impact factor: 3.079
Publication type: Paper in international publication
Authors: Saez-Gimenez, Berta, Berastegui, Cristina, Sintes, Helena, Perez, Javier, Figueredo, Ana, Lopez Meseguer, Manuel, Monforte, Victor, Bravo, Carlos, Santamaria, Amparo, Ramon, Maria Antonia et al.
DOI: 10.1111/tri.13021

Antibiotic resistance and population structure of cystic fibrosis Pseudomonas aeruginosa isolates from a Spanish multi-centre study.

PMID: 28735882
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2017
Reference: Int J Antimicrob Agents. 2017 Sep;50(3):334-341. doi: 10.1016/j.ijantimicag.2017.03.034. Epub 2017 Jul 20.
Impact factor: 4.307
Publication type: Clinical Trials
Authors: de Miguel, Maria Angeles, Garcia, Marta, Oliva, Concepcion, Prados, Maria Concepcion, Barrio, Maria Isabel, Pastor, Maria Dolores, Olveira, Casilda, de Gracia, Javier, Alvarez, Antonio, Escribano, Amparo et al.
DOI: 10.1016/j.ijantimicag.2017.03.034

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.