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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Off-pump technique and replacement therapy for coronary artery bypass surgery in a patient with hemophilia B.

PMID: 31152365
Journal: JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Year: 2019
Reference: J Thromb Thrombolysis. 2019 Aug;48(2):299-302. doi: 10.1007/s11239-019-01888-9.
Impact factor: 2.941
Publication type: Paper in international publication
Authors: Santamaria, A, Fernandez-Caballero, M, Martinez, M F, Oristrell, G, Palmer, N et al.
DOI: 10.1007/s11239-019-01888-9

Olaparib as maintenance treatment following first-line platinum-based chemotherapy in patients with a germline BRCA mutation and metastatic pancreatic cancer: phase III POLO trial.

PMID: 32085054
Journal: ANNALS OF ONCOLOGY
Year: 2019
Reference: Ann Oncol. 2019 Jul;30 Suppl 4:iv152. doi: 10.1093/annonc/mdz183. Epub 2019 Dec 4.
Impact factor: 14.196
Publication type: Letter or abstract
Authors: Golan, T, Van Cutsem, E, Macarulla, T, Hall, M, Park, J, Hochhauser, D, Arnold, D, Oh, D, Reinacher-Schick, A, Tortora, G et al.
DOI: 10.1093/annonc/mdz183

Oligoclonal bands do not represent dissemination in time in the 2017 revisions to the McDonald criteria.

PMID: 31094275
Journal: Multiple Sclerosis Journal
Year: 2019
Reference: Mult Scler. 2019 Oct;25(12):1690-1691. doi: 10.1177/1352458519846103. Epub 2019 May 16.
Impact factor: 5.649
Publication type: Paper in international publication
Authors: Tintore, Mar, Montalban, Xavier, Arrambide, Georgina et al.
DOI: 10.1177/1352458519846103

Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome.

PMID: 30915227
Journal: Multiple sclerosis journal - experimental, transla
Year: 2019
Reference: Mult Scler J Exp Transl Clin. 2019 Mar 20;5(1):2055217319836664. doi: 10.1177/2055217319836664. eCollection 2019 Jan-Mar.
Impact factor: 0
Publication type: Paper in international publication
Authors: Langille, Megan, Mathey, Guillaume, Neuteboom, Rinze F, Pelletier, Jean, Pohl, Daniela, Reich, Daniel S, Ignacio Rojas, Juan, Shabanova, Veronika, Shapiro, Eugene D, Stone, Robert T et al.
DOI: 10.1177/2055217319836664

One-shot domain adaptation in multiple sclerosis lesion segmentation using convolutional neural networks.

PMID: 30555005
Journal: NeuroImage-Clinical
Year: 2019
Reference: Neuroimage Clin. 2019;21:101638. doi: 10.1016/j.nicl.2018.101638. Epub 2018 Dec 10.
Impact factor: 3.943
Publication type: Paper in international publication
Authors: Valverde, Sergi, Salem, Mostafa, Cabezas, Mariano, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Salvi, Joaquim, Oliver, Arnau, Llado, Xavier et al.
DOI: 10.1016/j.nicl.2018.101638

ONE-STEP NUCLEIC ACID AMPLIFICATION FOR INTRAOPERATIVE ANALYSIS OF SENTINEL LYMPH NODE IN PAPILLARY THYROID CARCINOMA.

PMID: 30400049
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2019
Reference: Eur J Endocrinol. 2019 Jan 1;180(1):21-29. doi: 10.1530/EJE-18-0624.
Impact factor: 5.107
Publication type: Paper in international publication
Authors: Fort, Jose M, Pujol-Borrell, Ricardo, Ramon Y Cajal, Santiago, Gonzalez, Oscar, Castell, Joan, Mesa, Jordi, Roca, Isabel, Caubet, Enric, Iglesias Felip, Carmela, Zafon, Carles et al.
DOI: 10.1530/EJE-18-0624

Opportunistic testing of BRCA1, BRCA2 and mismatch repair genes improves the yield of phenotype driven hereditary cancer gene panels.

PMID: 30927264
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2019
Reference: Int J Cancer. 2019 Nov 15;145(10):2682-2691. doi: 10.1002/ijc.32304. Epub 2019 Apr 15.
Impact factor: 4.982
Publication type: Paper in international publication
Authors: Feliubadalo, Lidia, Lopez-Fernandez, Adria, Pineda, Marta, Diez, Orland, Del Valle, Jesus, Gutierrez-Enriquez, Sara, Teule, Alex, Gonzalez, Sara, Stjepanovic, Neda, Salinas, Monica et al.
DOI: 10.1002/ijc.32304

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis.

PMID: 31652649
Journal: Cells
Year: 2019
Reference: Cells. 2019 Oct 22;8(10). pii: cells8101299. doi: 10.3390/cells8101299.
Impact factor: 5.656
Publication type: Paper in international publication
Authors: Valls-Lacalle, Laura, Negre-Pujol, Corall, Rodriguez, Cristina, Varona, Saray, Valera-Canellas, Antoni, Consegal, Marta, Martinez-Gonzalez, Jose, Rodriguez-Sinovas, Antonio et al.
DOI: 10.3390/cells8101299

Optimal duration of treatment with eculizumab in atypical hemolytic uremic syndrome (aHUS)-a question to be addressed in a scientific way.

PMID: 30693384
Journal: PEDIATRIC NEPHROLOGY
Year: 2019
Reference: Pediatr Nephrol. 2019 May;34(5):943-949. doi: 10.1007/s00467-019-4192-7. Epub 2019 Jan 28.
Impact factor: 2.816
Publication type: Editorail in international publication
Authors: Ariceta, Gema et al.
DOI: 10.1007/s00467-019-4192-7

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.

PMID: 30647034
Journal: BMJ Open
Year: 2019
Reference: BMJ Open. 2019 Jan 15;9(1):e023455. doi: 10.1136/bmjopen-2018-023455.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Raj, Ashok, Pearse, Rupert M, Macdonald, Neil, Abbott, Tom, Martin, Tim, Januszewska, Marta, Niebrzegowska, Edyta, Bekele, Solana, Pates, Katherine, Haines, Ryan et al.
DOI: 10.1136/bmjopen-2018-023455

Optimisation of the use of APRI and FIB-4 to rule out cirrhosis in patients with chronic hepatitis B: results from the SONIC-B study.

PMID: 30975477
Journal: Lancet Gastroenterology & Hepatology
Year: 2019
Reference: Lancet Gastroenterol Hepatol. 2019 Jul;4(7):538-544. doi: 10.1016/S2468-1253(19)30087-1. Epub 2019 Apr 9.
Impact factor: 12.856
Publication type: Paper in international publication
Authors: Chan, Henry L-Y, Sonneveld, Milan J, Brouwer, Willem P, Zeuzem, Stefan, Liaw, Yun-Fan, Hansen, Bettina E, Choi, Hannah, Wat, Cynthia, Pavlovic, Vedran, Gaggar, Anuj et al.
DOI: 10.1016/S2468-1253(19)30087-1

Optimization of surgical treatment of advanced ovarian cancer: a Spanish expert perspective.

PMID: 30377941
Journal: Clinical & Translational Oncology
Year: 2019
Reference: Clin Transl Oncol. 2019 May;21(5):656-664. doi: 10.1007/s12094-018-1967-4. Epub 2018 Oct 30.
Impact factor: 2.441
Publication type: Paper in international publication
Authors: Chiva, L, Rodriguez-Garzotto, A, Gil-Moreno, A, Minig, L, de Santiago, J, Domingo, S, Martinez, S et al.
DOI: 10.1007/s12094-018-1967-4

Optimization of the neurosurgical patient in Intensive Care.

PMID: 30982626
Journal: Medicina Intensiva
Year: 2019
Reference: Med Intensiva. 2019 Nov;43(8):489-496. doi: 10.1016/j.medin.2019.02.011. Epub 2019 Apr 11.
Impact factor: 1.982
Publication type: Paper in national publication
Authors: Arikan Abello, F, Sanchez Corral, A, Ferrer Roca, R, Santafe Colomina, M et al.
DOI: 10.1016/j.medin.2019.02.011

Optimization of the Therapeutic Approach to Patients with Sarcoma: Delphi Consensus.

PMID: 31975783
Journal: Sarcoma
Year: 2019
Reference: Sarcoma. 2019 Dec 26;2019:4351308. doi: 10.1155/2019/4351308. eCollection 2019.
Impact factor: 0
Publication type: Review in international publication
Authors: Lopez Pousa, Antonio, Martin-Broto, Javier, Valverde, Claudia Maria, Giner, Javier Lavernia, Del Muro Solans, Xavier Garcia, Cruz Jurado, Josefina, Alvarez Alvarez, Rosa et al.
DOI: 10.1155/2019/4351308

Optimization of Transbronchial Cryobiopsy in Lung Transplant Recipients.

PMID: 31229481
Journal: ANNALS OF THORACIC SURGERY
Year: 2019
Reference: Ann Thorac Surg. 2019 Oct;108(4):1052-1058. doi: 10.1016/j.athoracsur.2019.04.096. Epub 2019 Jun 21.
Impact factor: 3.919
Publication type: Paper in international publication
Authors: Loor, Karina, Culebras, Mario, Sansano, Irene, Alvarez, Antonio, Berastegui, Cristina, de Gracia, Javier et al.
DOI: 10.1016/j.athoracsur.2019.04.096

Optimizing the management of locally advanced pancreatic cancer with a focus on induction chemotherapy: Expert opinion based on a review of current evidence.

PMID: 31163334
Journal: CANCER TREATMENT REVIEWS
Year: 2019
Reference: Cancer Treat Rev. 2019 Jul;77:1-10. doi: 10.1016/j.ctrv.2019.05.007. Epub 2019 May 29.
Impact factor: 8.332
Publication type: Review in international publication
Authors: Seufferlein, Thomas, Hammel, Pascal, Delpero, Jean Robert, Macarulla, Teresa, Pfeiffer, Per, Prager, Gerald W, Reni, Michele, Falconi, Massimo, Philip, Philip A, Van Cutsem, Eric et al.
DOI: 10.1016/j.ctrv.2019.05.007

Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial.

PMID: 31533777
Journal: BREAST CANCER RESEARCH
Year: 2019
Reference: Breast Cancer Res. 2019 Sep 18;21(1):108. doi: 10.1186/s13058-019-1195-z.
Impact factor: 5.676
Publication type: Paper in international publication
Authors: Amillano, Kepa, Adamo, Barbara, Bellet, Meritxell, Pare, Laia, Pascual, Tomas, Vidal, Maria, Perez Fidalgo, Jose A, Blanch, Salvador, Martinez, Noelia, Murillo, Laura et al.
DOI: 10.1186/s13058-019-1195-z

Origins of DNA methylation defects in Wilms tumors.

PMID: 31103718
Journal: CANCER LETTERS
Year: 2019
Reference: Cancer Lett. 2019 Aug 10;457:119-128. doi: 10.1016/j.canlet.2019.05.013. Epub 2019 May 16.
Impact factor: 6.508
Publication type: Paper in international publication
Authors: Anvar, Zahra, Acurzio, Basilia, Roma, Josep, Cerrato, Flavia, Verde, Gaetano et al.
DOI: 10.1016/j.canlet.2019.05.013

Osteogenic commitment of Wharton's jelly mesenchymal stromal cells: mechanisms and implications for bioprocess development and clinical application.

PMID: 31779673
Journal: Stem Cell Research & Therapy
Year: 2019
Reference: Stem Cell Res Ther. 2019 Nov 28;10(1):356. doi: 10.1186/s13287-019-1450-3.
Impact factor: 4.627
Publication type: Paper in international publication
Authors: Cabrera-Perez, Raquel, Monguio-Tortajada, Marta, Gamez-Valero, Ana, Rojas-Marquez, Raquel, Borras, Francesc Enric, Roura, Santiago, Vives, Joaquim et al.
DOI: 10.1186/s13287-019-1450-3

Outcome, efficacy and safety of endovascular thrombectomy in ischaemic stroke according to time to reperfusion: data from a multicentre registry.

PMID: 30944585
Journal: Therapeutic Advances in Neurological Disorders
Year: 2019
Reference: Ther Adv Neurol Disord. 2019 Mar 27;12:1756286419835708. doi: 10.1177/1756286419835708. eCollection 2019.
Impact factor: 3.58
Publication type: Paper in international publication
Authors: Gralla, Jan, Meinel, Thomas Raphael, Kaesmacher, Johannes, Mordasini, Pasquale, Mosimann, Pascal J, Jung, Simon, Arnold, Marcel, Heldner, Mirjam Rachel, Michel, Patrik, Hajdu, Steven D et al.
DOI: 10.1177/1756286419835708

Outcome in Direct Versus Transfer Patients in the DAWN Controlled Trial.

PMID: 31303153
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Aug;50(8):2163-2167. doi: 10.1161/STROKEAHA.119.025710. Epub 2019 Jul 15.
Impact factor: 6.046
Publication type: Paper in international publication
Authors: Smith, Wade S, Aghaebrahim, Amin, Jadhav, Ashutosh P, Hanel, Ricardo, Sauvageau, Eric, Granja, Manuel F, Zhang, Yanchang, Haussen, Diogo C, Budzik, Ronald F, Bonafe, Alain et al.
DOI: 10.1161/STROKEAHA.119.025710

Outcome of kidney transplantation from young pediatric donors (aged less than 6 years) to young size-matched recipients.

PMID: 31005637
Journal: Journal of Pediatric Urology
Year: 2019
Reference: J Pediatr Urol. 2019 May;15(3):213-220. doi: 10.1016/j.jpurol.2019.03.015. Epub 2019 Mar 28.
Impact factor: 1.736
Publication type: Review in international publication
Authors: Gander, R, Asensio, M, Molino, J A, Lara, L E, Lopez, M, Lopez, M, Ariceta, G, Royo, G F et al.
DOI: 10.1016/j.jpurol.2019.03.015

Outcome of localized liver-bile duct rhabdomyosarcoma according to local therapy: A report from the European Paediatric Soft-Tissue Sarcoma Study Group (EpSSG)-RMS 2005 study.

PMID: 30920113
Journal: PEDIATRIC BLOOD & CANCER
Year: 2019
Reference: Pediatr Blood Cancer. 2019 Jul;66(7):e27725. doi: 10.1002/pbc.27725. Epub 2019 Mar 28.
Impact factor: 2.486
Publication type: Paper in international publication
Authors: Rogers, Timothy, Minard-Colin, Veronique, Gaze, Mark N, Terwisscha, Sheila, Van Noesel, Max, De Corti, Federica, Guillen Burrieza, Gabriela, De Salvo, Gian Luca, Kelsey, Anna, Orbach, Daniel et al.
DOI: 10.1002/pbc.27725

Outcomes by sex following treatment initiation with darunavir/cobicistat in a large Spanish cohort of the CODAR study (GeSIDA 9316).

PMID: 31236601
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2019
Reference: J Antimicrob Chemother. 2019 Oct 1;74(10):3044-3048. doi: 10.1093/jac/dkz254.
Impact factor: 5.113
Publication type: Paper in international publication
Authors: de La Fuente Moral, S, Perez Elias, M J, Alejos, B, Vivancos, M J, Ribera, E, Galindo, M J, Vilanova-Trillo, L, Garcia-Fraile Fraile, L J, Sanz, Jose, de Los Santos, Ignacio et al.
DOI: 10.1093/jac/dkz254