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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS.

PMID: 26024899
Journal: NEUROLOGY
Year: 2015
Reference: Neurology. 2015 Jul 7;85(1):29-39. doi: 10.1212/WNL.0000000000001706. Epub 2015 May 29.
Impact factor: 8.286
Publication type: Clinical Trials
Authors: Griffiths, Sarah, von Rosenstiel, Philipp, Gottschalk, Rebecca, Zhang, Ying, Dahlke, Frank, Tomic, Davorka, Mueller-Lenke, Nicole, Sprenger, Till, Derfuss, Tobias, Kappos, Ludwig et al.
DOI: 10.1212/WNL.0000000000001706

Switching from zidovudine/lamivudine to tenofovir/emtricitabine improves fat distribution as measured by fat mass ratio.

PMID: 25496141
Journal: HIV MEDICINE
Year: 2015
Reference: HIV Med. 2015 Jul;16(6):370-4. doi: 10.1111/hiv.12210. Epub 2014 Dec 11.
Impact factor: 3.454
Publication type: Paper in international publication
Authors: Martinez, E, Ribera, E, Clotet, B, Estrada, V, Sanz, J, Berenguer, J, Rubio, R, Pulido, F, Larrousse, M, Curran, A et al.
DOI: 10.1111/hiv.12210

Switching to second-generation tyrosine kinase inhibitor improves the response and outcome of frontline imatinib-treated patients with chronic myeloid leukemia with more than 10% of BCR-ABL/ABL ratio at 3 months.

PMID: 25756742
Journal: Cancer Medicine
Year: 2015
Reference: Cancer Med. 2015 Jul;4(7):995-1002. doi: 10.1002/cam4.440. Epub 2015 Mar 10.
Impact factor: 2.5
Publication type: Paper in international publication
Authors: Garcia-Gutierrez, Jose-Valentin, Massague, Isabel, Giraldo, Pilar, Perez-Encinas, Manuel, de Paz, Raquel, Martinez-Lopez, Joaquin, Bautista, Guiomar, Osorio, Santiago, Requena, Maria-Jose, Palomera, Luis et al.
DOI: 10.1002/cam4.440

Syncope Unit: rationale and requirement - the European Heart Rhythm Association position statement endorsed by the Heart Rhythm Society.

PMID: 26108809
Journal: EUROPACE
Year: 2015
Reference: Europace. 2015 Sep;17(9):1325-40. doi: 10.1093/europace/euv115. Epub 2015 Jun 24.
Impact factor: 3.67
Publication type: Paper in international publication
Authors: Benditt, David, Krahn, Andrew, Morillo, Carlos Arturo, Olshansky, Brian, Raj, Satish, Sheldon, Robert, Shen, Win Kuang, Sun, Benjamin, Hachul, Denise, Abe, Haruhiko et al.
DOI: 10.1093/europace/euv115

Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis.

PMID: 25761863
Journal: HEPATOLOGY
Year: 2015
Reference: Hepatology. 2015 Sep;62(3):762-72. doi: 10.1002/hep.27779. Epub 2015 Apr 13.
Impact factor: 11.055
Publication type: Paper in international publication
Authors: Affo, Silvia, Morales-Ibanez, Oriol, Sancho-Bru, Pau, Dominguez, Marlene, Garcia-Pagan, Juan Carlos, Fernandez, Javier, Arroyo, Vicente, Gines, Pere, Louvet, Alexandre, Mathurin, Philippe et al.
DOI: 10.1002/hep.27779

Takotsubo cardiomyopathy and elderly adults: still a benign condition?

PMID: 25688623
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2015
Reference: J Am Geriatr Soc. 2015 Feb;63(2):404-7. doi: 10.1111/jgs.13276.
Impact factor: 4.572
Publication type: Letter whit IF
Authors: Nunez-Gil, Ivan J, Sionis, Alessandro, Andres, Mireia, Almendro Delia, Manuel, Martin, Ana, Lozano, Alvaro, Cordoba Soriano, Juan Gabriel, Linares Vicente, Jose A, Gonzalez Sucarrats, Silvia, Sanchez Grande Flecha, Alejandro et al.
DOI: 10.1111/jgs.13276

Tamoxifen administration to mice.

PMID: 25734062
Journal: Cold Spring Harbor protocols
Year: 2015
Reference: Cold Spring Harb Protoc. 2015 Mar 2;2015(3):269-71. doi: 10.1101/pdb.prot077966.
Impact factor: 0
Publication type: Paper in international publication
Authors: Whitfield, Jonathan, Littlewood, Trevor, Soucek, Laura et al.
DOI: 10.1101/pdb.prot077966

Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity.

PMID: 25407002
Journal: EUROPEAN JOURNAL OF HUMAN GENETICS
Year: 2015
Reference: Eur J Hum Genet. 2015 Sep;23(9):1192-9. doi: 10.1038/ejhg.2014.252. Epub 2014 Nov 19.
Impact factor: 4.225
Publication type: Paper in international publication
Authors: Trujillano, Daniel, Santin, Sheila, Ossowski, Stephan, Mendizabal, Santiago, Fraga, Gloria, Madrid, Alvaro, Ariceta, Gema, Ballarin, Jose, Torra, Roser, Ars, Elisabet et al.
DOI: 10.1038/ejhg.2014.252

Targeted therapy for genetic cancer syndromes: Fanconi anemia, medullary thyroid cancer, tuberous sclerosis, and RASopathies.

PMID: 25725224
Journal: Discovery Medicine
Year: 2015
Reference: Discov Med. 2015 Feb;19(103):101-8.
Impact factor: 3.626
Publication type: Review in international publication
Authors: Agarwal, Rishi, Liebe, Sarah, Turski, Michelle L, Vidwans, Smruti J, Janku, Filip, Garrido-Laguna, Ignacio, Munoz, Javier, Schwab, Richard, Rodon, Jordi, Kurzrock, Razelle et al.
DOI:

Targeted therapy for genetic cancer syndromes: Von Hippel-Lindau disease, Cowden syndrome, and Proteus syndrome.

PMID: 25725225
Journal: Discovery Medicine
Year: 2015
Reference: Discov Med. 2015 Feb;19(103):109-16.
Impact factor: 3.626
Publication type: Review in international publication
Authors: Agarwal, Rishi, Liebe, Sarah, Turski, Michelle L, Vidwans, Smruti J, Janku, Filip, Garrido-Laguna, Ignacio, Munoz, Javier, Schwab, Richard, Rodon, Jordi, Kurzrock, Razelle et al.
DOI:

Targeting a cell state common to triple-negative breast cancers.

PMID: 25699542
Journal: Molecular Systems Biology
Year: 2015
Reference: Mol Syst Biol. 2015 Feb 19;11(1):789. doi: 10.15252/msb.20145664.
Impact factor: 10.872
Publication type: Paper in international publication
Authors: Kerzendorfer, Claudia, Lechtermann, Hannelore, Trefzer, Claudia, Klepsch, Freya, Muller, Andre C, Leitner, Ernestine, Macho-Maschler, Sabine, Superti-Furga, Giulio, Bennett, Keiryn L, Baselga, Jose et al.
DOI: 10.15252/msb.20145664

Targeting alpha-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations.

PMID: 26050140
Journal: LANCET NEUROLOGY
Year: 2015
Reference: Lancet Neurol. 2015 Aug;14(8):855-66. doi: 10.1016/S1474-4422(15)00006-X. Epub 2015 Jun 3.
Impact factor: 21.896
Publication type: Paper in international publication
Authors: Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stephane, Singleton, Andrew, Olanow, C Warren, Merchant, Kalpana M, Bezard, Erwan et al.
DOI: 10.1016/S1474-4422(15)00006-X

Tenofovir discontinuation after long-term viral suppression in HBeAg negative chronic hepatitis B. Can HBsAg levels be useful?

PMID: 26071338
Journal: JOURNAL OF CLINICAL VIROLOGY
Year: 2015
Reference: J Clin Virol. 2015 Jul;68:61-8. doi: 10.1016/j.jcv.2015.05.002. Epub 2015 May 8.
Impact factor: 3.016
Publication type: Paper in international publication
Authors: Buti, Maria, Casillas, Rosario, Riveiro-Barciela, Mar, Homs, Maria, Tabernero, David, Salcedo, Maria Teresa, Rodriguez-Frias, Francisco, Esteban, Rafael et al.
DOI: 10.1016/j.jcv.2015.05.002

Tenofovir disoproxil fumarate in Asian or Pacific Islander chronic hepatitis B patients with high viral load (>/= 9 log copies/ml).

PMID: 25277773
Journal: LIVER INTERNATIONAL
Year: 2015
Reference: Liver Int. 2015 Feb;35(2):422-8. doi: 10.1111/liv.12694. Epub 2014 Oct 28.
Impact factor: 4.85
Publication type: Paper in international publication
Authors: Fung, Scott, Horban, Andrzej, Petersen, Jorg, Sperl, Jan, Gane, Edward, Jacobson, Ira M, Yee, Leland J, Dinh, Phillip, Martins, Eduardo B, Flaherty, John F et al.
DOI: 10.1111/liv.12694

The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.

PMID: 25810396
Journal: JOURNAL OF IMMUNOLOGY
Year: 2015
Reference: J Immunol. 2015 May 1;194(9):4309-18. doi: 10.4049/jimmunol.1402887. Epub 2015 Mar 25.
Impact factor: 4.922
Publication type: Paper in international publication
Authors: Serrano-Candelas, Eva, Alvarez-Errico, Damiana, Picado, Cesar, Sayos, Joan, Rivera, Juan, Martin, Margarita, Ainsua-Enrich, Erola et al.
DOI: 10.4049/jimmunol.1402887

The administration of probiotics and synbiotics in immune compromised adults: is it safe?

PMID: 25304690
Journal: Beneficial Microbes
Year: 2015
Reference: Benef Microbes. 2015 Mar;6(1):3-17. doi: 10.3920/BM2014.0079.
Impact factor: 2.614
Publication type: Paper in international publication
Authors: Van den Nieuwboer, M, Brummer, R J, Guarner, F, Morelli, L, Cabana, M, Claassen, E et al.
DOI: 10.3920/BM2014.0079

The asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): opportunities and challenges.

PMID: 25405671
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2015
Reference: Curr Opin Pulm Med. 2015 Jan;21(1):74-9. doi: 10.1097/MCP.0000000000000118.
Impact factor: 2.756
Publication type: Paper in international publication
Authors: Miravitlles, Marc, Barrecheguren, Miriam, Esquinas, Cristina et al.
DOI: 10.1097/MCP.0000000000000118

The Burden of Neglected HIV-2 and HTLV-1 Infections in Spain.

PMID: 26616845
Journal: AIDS REVIEWS
Year: 2015
Reference: AIDS Rev. 2015 Oct-Dec;17(4):212-9.
Impact factor: 3.787
Publication type: Review in international publication
Authors: Penaranda, M, Trevino, Ana, Caballero, Estrella, de Mendoza, Carmen, Aguilera, Antonio, Piron, Maria, Soriano, Vicente, Rodriguez, C, Vera, M, del Romero, J et al.
DOI:

The CAT (COPD Assessment Test) questionnaire as a predictor of the evolution of severe COPD exacerbations.

PMID: 26542727
Journal: RESPIRATORY MEDICINE
Year: 2015
Reference: Respir Med. 2015 Dec;109(12):1546-52. doi: 10.1016/j.rmed.2015.10.011. Epub 2015 Oct 27.
Impact factor: 2.593
Publication type: Paper in international publication
Authors: Herrejon, Alberto, Malo de Molina, Rosa, Marcos, Pedro Jorge, Mayoralas-Alises, Sagrario, Ros, Jose Antonio, Valle, Manuel, Esquinas, Cristina, Barrecheguren, Miriam, Miravitlles, Marc, Garcia-Rivero, Juan Luis et al.
DOI: 10.1016/j.rmed.2015.10.011

The chronic obstructive pulmonary disease assessment test improves the predictive value of previous exacerbations for poor outcomes in COPD.

PMID: 26664105
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2015
Reference: Int J Chron Obstruct Pulmon Dis. 2015 Nov 30;10:2571-9. doi: 10.2147/COPD.S91163. eCollection 2015.
Impact factor: 3.141
Publication type: Paper in international publication
Authors: Miravitlles, Marc, Garcia-Sidro, Patricia, Fernandez-Nistal, Alonso, Buendia, Maria Jesus, Espinosa de Los Monteros, Maria Jose, Esquinas, Cristina, Molina, Jesus et al.
DOI: 10.2147/COPD.S91163

The clinical positioning of telavancin in Europe.

PMID: 25600892
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2015
Reference: Int J Antimicrob Agents. 2015 Mar;45(3):213-20. doi: 10.1016/j.ijantimicag.2014.12.006. Epub 2014 Dec 24.
Impact factor: 4.296
Publication type: Paper in international publication
Authors: Torres, Antoni, Rello, Jordi, Lode, Hartmut M, Courvalin, Patrice, Cornaglia, Giuseppe, Masterton, Robert et al.
DOI: 10.1016/j.ijantimicag.2014.12.006

The consensus molecular subtypes of colorectal cancer.

PMID: 26457759
Journal: NATURE MEDICINE
Year: 2015
Reference: Nat Med. 2015 Nov;21(11):1350-6. doi: 10.1038/nm.3967. Epub 2015 Oct 12.
Impact factor:
Publication type: Paper in international publication
Authors: Angelino, Paolo; Barras, David; Bernards, Rene; Boige, Valerie; Bot, Brian M; Broom, Bradley; de Reynies, Aurelien; De Sousa E Melo, Felipe; Delorenzi, Mauro; Dienstmann, Rodrigo et al.
DOI: 10.1038/nm.3967

[The development of Spanish paediatric cardiology and its impact on congenital heart disease management].

PMID: 26283323
Journal: ANALES DE PEDIATRIA
Year: 2015
Reference: An Pediatr (Barc). 2015 Nov;83(5):295-6. doi: 10.1016/j.anpedi.2015.07.022. Epub 2015 Aug 15.
Impact factor: 0.833
Publication type: Editorial in national publication
Authors: Albert Brotons, D C et al.
DOI: 10.1016/j.anpedi.2015.07.022

The effect of environmental chemicals on the tumor microenvironment.

PMID: 26106136
Journal: CARCINOGENESIS
Year: 2015
Reference: Carcinogenesis. 2015 Jun;36 Suppl 1:S160-83. doi: 10.1093/carcin/bgv035.
Impact factor: 5.334
Publication type: Review in international publication
Authors: Whitfield, Jonathan R, Curran, Colleen S, Forte, Stefano, Hamid, Roslida A, Heneberg, Petr, Koch, Daniel C, Krishnakumar, P K, Laconi, Ezio, Maguer-Satta, Veronique, Marongiu, Fabio et al.
DOI: 10.1093/carcin/bgv035