About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.
At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.
PMID: 37976444 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2023 Reference: J Clin Oncol. 2023 Nov 17:JCO2301363. doi: 10.1200/JCO.23.01363. Impact factor: Publication type: Paper in international publication Authors: Alegre-Martin, Jose; Bryl, Maciej; Castro-Marrero, Jesus; Chiu, Chao-Hua; Dumoulin, Daphne W; Hoang, Tien; Hong, Min Hee; Huang, Meilin; Johnson, Melissa; Jurek, Joanna et al. DOI: 10.1200/JCO.23.01363
PMID: 37995294 Journal: RHEUMATOLOGY Year: 2023 Reference: Rheumatology (Oxford). 2023 Nov 23:kead614. doi: 10.1093/rheumatology/kead614. Impact factor: Publication type: Paper in international publication Authors: Blasi, Joan; Bong, David A; Chu, Winnie C; Concepcion, Nathan David P; Coronel, Luis; D'Agostino, Maria Antonietta; Daltro, Pedro; DiPrete, Olivia; Garcia-Pena, Pilar; Kasznia-Brown, Joanna et al. DOI: 10.1093/rheumatology/kead614
PMID: 38002647 Journal: Journal of Clinical Medicine Year: 2023 Reference: J Clin Med. 2023 Nov 10;12(22):7033. doi: 10.3390/jcm12227033. Impact factor: Publication type: Paper in international publication Authors: Blasi, Joan; Bong, David A; Coronel, Luis; D'Agostino, Maria Antonietta; Mandl, Peter; Martinoli, Carlo; Miguel-Perez, Maribel; Moller, Ingrid; Montane, Eva; Sabate, Monica et al. DOI: 10.3390/jcm12227033
PMID: 38086222 Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY Year: 2023 Reference: Eur Neuropsychopharmacol. 2023 Dec 11;79:32-37. doi: 10.1016/j.euroneuro.2023.10.004. Impact factor: Publication type: Paper in international publication Authors: Alfonso, Miqueu; Amoretti, Silvia; Anmella, Gerard; Arranz, Belen; Benson, Mikael; Bernardo, Miquel; Dal Santo, Francesco; Eklund, Desire; Garcia-Portilla, Maria Paz; Gawel, Danuta et al. DOI: 10.1016/j.euroneuro.2023.10.004
PMID: 34099189 Journal: Biological Psychiatry Year: 2022 Reference: Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23. Impact factor: Publication type: Paper in international publication Authors: Abbott, Liam; Abdellaoui, Abdel; Adams, Mark J; Adams, Mark J; Adolfsson, Annelie Nordin; Adolfsson, Rolf; Adolfsson, Rolf; Agartz, Ingrid; Agerbo, Esben; Agerbo, Esben et al. DOI: 10.1016/j.biopsych.2021.02.972
PMID: 35051890 Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM Year: 2022 Reference: Semin Arthritis Rheum. 2022 Apr;53:151940. doi: 10.1016/j.semarthrit.2021.12.008. Epub 2021 Dec 31. Impact factor: Publication type: Paper in international publication Authors: Alvarado-Cardenas, M; Gil-Vila, Albert; Martinez-Gomez, X; Pinal-Fernandez, Iago; Selva-O'Callaghan, Albert; Simo-Perdigo, M; Trallero-Araguas, Ernesto et al. DOI: 10.1016/j.semarthrit.2021.12.008
PMID: 34649820 Journal: Reumatologia clinica Year: 2022 Reference: Reumatol Clin. 2022 Mar;18(3):131-140. doi: 10.1016/j.reumae.2021.02.002. Epub 2021 Oct 11. Impact factor: Publication type: Paper in international publication Authors: Alegre de Miquel, Cayetano; Almirall Bernabe, Miriam; Brito Garcia, Noe; Casanueva Fernandez, Benigno; Castillo Ojeda, Cristina; Collado Cruz, Antonio; Diaz Del Campo Fontecha, Petra; Merino Argumanez, Carol; Monteso-Curto, Pilar; Palao Tarrero, Angela et al. DOI: 10.1016/j.reuma.2021.02.004
PMID: 34893470 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2022 Reference: Ann Rheum Dis. 2022 Apr;81(4):490-495. doi: 10.1136/annrheumdis-2021-220964. Epub 2021 Dec 10. Impact factor: Publication type: Paper in international publication Authors: Alabas, Oras A; Dubash, Sayam; Emery, Paul; Garcia-Montoya, Leticia; Helliwell, Philip S; Marzo-Ortega, Helena; McGonagle, Dennis G; Michelena, Xabier; Tan, Ai Lyn; Wakefield, Richard J et al. DOI: 10.1136/annrheumdis-2021-220964
PMID: 33898490 Journal: Frontiers in Medicine Year: 2021 Reference: Front Med (Lausanne). 2021 Apr 9;8:656667. doi: 10.3389/fmed.2021.656667. eCollection 2021. Impact factor: Publication type: Paper in international publication Authors: Azuaga, Ana Belen; Canete, Juan D; Celis, Raquel; Cuervo, Andrea; Fare, Regina; Julia, Antonio; Lorenzo, Andres; Pablos, Jose L; Ramirez, Julio; Sanmarti, Raimon et al. DOI: 10.3389/fmed.2021.656667
PMID: 33893449 Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION Year: 2021 Reference: Eur J Clin Nutr. 2021 Sep;75(9):1368-1382. doi: 10.1038/s41430-021-00913-6. Epub 2021 Apr 23. Impact factor: Publication type: Paper in international publication Authors: Almaraz, Esther Rodriguez; Alperi, Mercedes; Andreu, Jose Luis; Aterido, Adria; Aterido, Adria; Barreiro-de Acosta, Manuel; Blanco, Francisco; Blanco, Ricardo; Canete, Juan D; Carazo, Jose Luis Sanchez et al. DOI: 10.1038/s41430-021-00913-6
PMID: 33882889 Journal: BMC MUSCULOSKELETAL DISORDERS Year: 2021 Reference: BMC Musculoskelet Disord. 2021 Apr 21;22(1):372. doi: 10.1186/s12891-021-04248-y. Impact factor: Publication type: Paper in international publication Authors: Alperi, Mercedes; Blanco, Francisco; Castellanos-Moreira, Raul; Diaz-Torne, Cesar; Erra, Alba; Fernandez-Nebro, Antonio; Gomez, Antonio; Gonzalez, Isidoro; Haro, Isabel; Julia, Antonio et al. DOI: 10.1186/s12891-021-04248-y
PMID: 33867271 Journal: Reumatologia clinica Year: 2021 Reference: Reumatol Clin (Engl Ed). 2021 Apr 15:S1699-258X(21)00065-6. doi: 10.1016/j.reuma.2021.01.007. Impact factor: Publication type: Paper in national publication Authors: Alcocer, Patricia; Barbadillo, Carmen; Belzunegui, Joaquin; Camins, Jordi; Carrasco Cubero, Carmen; Carrion-Barbera, Irene; Castellvi, Ivan; Cobo-Ibanez, Tatiana; Delgado-Frias, Esmeralda; Freire, Mercedes et al. DOI: 10.1016/j.reuma.2021.01.007
PMID: 32351168 Journal: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY Year: 2020 Reference: Scand J Rheumatol. 2020 Jul;49(4):259-266. doi: 10.1080/03009742.2020.1726449. Epub 2020 Apr 30. Impact factor: Publication type: Paper in international publication Authors: Combe, B; Fautrel, B; Guillemin, F; Lukas, C; Marsal, S; Olive, A; Rincheval, N; Rodriguez-Muguruza, S; Valero, O et al. DOI: 10.1080/03009742.2020.1726449
PMID: 32295620 Journal: ARTHRITIS RESEARCH & THERAPY Year: 2020 Reference: Arthritis Res Ther. 2020 Apr 15;22(1):82. doi: 10.1186/s13075-020-02168-1. Impact factor: Publication type: Paper in international publication Authors: Abad, Miguel Angel; Bermudez, Alberto; Cabez, Ana; Calvo-Alen, Jaime; Canete, Juan D; Cobeta, Juan Carlos; Fernandez, Pilar; Garcia, M Luz; Gomez, Susana; Gonzalez, Beatriz et al. DOI: 10.1186/s13075-020-02168-1
PMID: 32291908 Journal: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Year: 2020 Reference: J Cell Mol Med. 2020 May;24(10):5865-5877. doi: 10.1111/jcmm.15260. Epub 2020 Apr 14. Impact factor: Publication type: Paper in international publication Authors: Alegre, Jose; Almenar-Perez, Eloy; Bekheit, Mina; Castro-Marrero, Jesus; Cheema, Amanpreet K; Collado, Fanny; Fletcher, Mary A; Klimas, Nancy G; Martin-Martinez, Eva; Nathanson, Lubov et al. DOI: 10.1111/jcmm.15260
PMID: 32182400 Journal: Arthritis & Rheumatology Year: 2020 Reference: Arthritis Rheumatol. 2020 Jul;72(7):1236. doi: 10.1002/art.41262. Epub 2020 May 27. Impact factor: Publication type: Paper in international publication Authors: Camprodon-Gomez, Maria; Fernandez-Codina, Andreu; Pope, Janet E et al. DOI: 10.1002/art.41262
PMID: 30907380 Journal: Revista Espanola de Salud Publica Year: 2019 Reference: Rev Esp Salud Publica. 2019 Mar 25;93. Impact factor: Publication type: Letter or abstract Authors: Adan, Alfredo; Andreu, Jose Luis; Arraiza, Antonio; Casado, Paloma; Cervera, Ricard; Codesido, Maria; Dauden, Esteban; Escobar, Carina; Gil, Angel; Hinojosa, Joaquin et al. DOI:
PMID: 30893475 Journal: EUROPEAN JOURNAL OF IMMUNOLOGY Year: 2019 Reference: Eur J Immunol. 2019 Jul;49(7):1107-1116. doi: 10.1002/eji.201848065. Epub 2019 Apr 2. Impact factor: Publication type: Paper in international publication Authors: Anez, Gustavo A; Campos-Caro, Antonio; de la Varga-Martinez, Raquel; Medina-Varo, Fermin; Rodriguez, Carmen; Rodriguez-Bayona, Beatriz et al. DOI: 10.1002/eji.201848065
PMID: 30552173 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Mar;78(3). pii: annrheumdis-2018-214158. doi: 10.1136/annrheumdis-2018-214158. Epub 2018 Dec 14. Impact factor: Publication type: Paper in international publication Authors: Absher, Devin; Alperi-Lopez, Mercedes; Aterido, Adria; Blanco, Francisco; Blanco, Ricardo; Bonas-Guarch, Silvia; Canete, Juan D; Castaneda, Santos; Codo, Laia; Corominas, Hector et al. DOI: 10.1136/annrheumdis-2018-214158
PMID: 30760090 Journal: LUPUS Year: 2019 Reference: Lupus. 2019 Mar;28(3):396-405. doi: 10.1177/0961203319828521. Epub 2019 Feb 13. Impact factor: Publication type: Paper in international publication Authors: Agraz, I; Alvarez-Rios, A M; Cortes-Hernandez, J; Garcia-Vives, E; Moline, T; Ordi-Ros, J; Sole, C; Vidal, M et al. DOI: 10.1177/0961203319828521
Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs
The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.
It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.
