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Shock, Organ Dysfunction and Resuscitation

The goal of the Shock, Organic Dysfunction and Resuscitation Research Group (SODIR) is comprehensive, innovative research into the areas of shock, acute respiratory failure, acute kidney failure, organic dysfunction, resuscitation and critical patient monitoring. In addition, the research group has a special interest in applying artificial intelligence as an instrument to find innovative solutions for critical patients.

Team

Ricard Ferrer Roca

Ricard Ferrer Roca

Head of group
Shock, Organ Dysfunction and Resuscitation
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Juan Carlos Ruiz Rodriguez

Juan Carlos Ruiz Rodriguez

Main researcher
Shock, Organ Dysfunction and Resuscitation
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Marcos Pérez Carrasco

Marcos Pérez Carrasco

Shock, Organ Dysfunction and Resuscitation
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Jordi Riera del Brío

Jordi Riera del Brío

Shock, Organ Dysfunction and Resuscitation
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Sandra Renard Tissedre

Sandra Renard Tissedre

Shock, Organ Dysfunction and Resuscitation
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Aguado Lain, Carmen

Aguado Lain, Carmen

Shock, Organ Dysfunction and Resuscitation
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Ricard Ferrer Roca

Ricard Ferrer Roca

Head of group
Shock, Organ Dysfunction and Resuscitation
Read more
Juan Carlos Ruiz Rodriguez

Juan Carlos Ruiz Rodriguez

Main researcher
Shock, Organ Dysfunction and Resuscitation
Read more
Marcos Pérez Carrasco

Marcos Pérez Carrasco

Shock, Organ Dysfunction and Resuscitation
Read more
Jordi Riera del Brío

Jordi Riera del Brío

Shock, Organ Dysfunction and Resuscitation
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Sandra Renard Tissedre

Sandra Renard Tissedre

Shock, Organ Dysfunction and Resuscitation
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Aguado Lain, Carmen

Aguado Lain, Carmen

Shock, Organ Dysfunction and Resuscitation
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Research lines

Research line in ECMO

The research line in ECMO, led by Dr. J. Riera, aims at clinical research in ECMO and the development of advanced simulation models in ECMO with the technology industry, such as the Hybrids VITA system, already marketed, which allows the realization of ECMO in a realistic simulation environment.

IP: Jordi Riera del Brío

Critically ill patient monitoring

The research line in  critically ill patient monitoring, led by Dr.J.C.Ruiz, has as objectives the research in the application of echocardiography and other non-invasive or minimally invasive monitoring systems in the study of the pathophysiological mechanisms of the hemodynamic and cardiac dysfunction of the critical patient, and the study of microcirculation and its involvement in the pathophysiology of severe sepsis with multiorgan dysfunction.

IP: Juan Carlos Ruiz Rodriguez

Clinical Research Unit

SODIR has created the Clinical Research Unit for to participate in the clinical trials promoted by the industry. This Unit centralizes all the clinical trials that are developed in the Group and allows a professional management of clinical trials, being a very positive and highly valued imput by the pharma companys. The Unit also give support to competitive research projects. Actually we are working in 14 clinical trials focused mainly on the field of sepsis and infectious diseases. The Unit is formed by nursing and doctors exclusively dedicated to clinical research (24 hours, 7 days/week).

IP: Ricard Ferrer Roca

Acute kidney failure in critical ill patients

The research line acute renal failure kidney focuses in extracorporeal replacement therapies and acute kidney injury.


Mainly attention has been focused on continuous renal replacement therapy (CRRT), to which absorptive therapies and hepatic replacement therapies have been linked. In relation to CRRT we have recently participated in the REGISFRA multicentric study, whose objective was to draw a map of CRRT in Catalonia. In addition, our attention is focused on projects of therapy optimization concerning type and dosage as well as in biomarkers that can early predict the requirement of CRRT in our patients.


In relation to acute kidney injury (AKI), the projects are based on the early recognition of patients at risk for AKI and on the prophylactic measures necessary to prevent these patients from finally developing an AKI.

IP: Marcos Pérez Carrasco

Projects

Impacte d'una intervenció multimodal sobre la perspectiva i satisfacció dels pacients, familiars i professionals de la Unitat de Cures Intensives.

IP: Montserrat Aran Esteve
Collaborators: Rocio Tabernero Gallego, Elisabet Gallart Vive, Rosa Maria Gracia Gozalo, Montse Rodriguez Gomez, Xavier Nuvials Casals, Nuria Vidal Tarrasón, Isidro Alcalà Jimenez, Adoración Nieto Ruiz, Laia Rafel Perez
Funding agency: Col·legi Oficial d'Infermers/es de Barcelona
Funding: 7502
Reference: PR-724/2024
Duration: 01/01/2025 - 31/12/2027

Validación clínica de Heecap, un sistema de electroestimulación no invasiva de la musculatura respiratoria para pacientes bajo ventilación mecánica.

IP: Ricard Ferrer Roca
Collaborators: Andres Francisco Pacheco Reyes, Alba Gómez Garrido, Francisco Javier Ramos Gómez, Gonzalo Ballesteros Reviriego
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 221996
Reference: CPP2023-010467
Duration: 01/05/2024 - 30/04/2027

Ministerio de Ciencia

INDICATE: A Federated Infrastructure for ICU Data across Europe

IP: Ricard Ferrer Roca
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 97370
Reference: INDICATE_HE_DIGI-2024
Duration: 01/12/2024 - 31/03/2028

Capacidad predictiva de la "impresión subjetiva de la enfermera" en la detección del riesgo de deterioro agudo de los pacientes hospitalizados.

IP: Sara López Branchadell
Collaborators: Esperanza Zuriguel Pérez, Juan Carlos Ruiz Rodriguez, Patricia Rubio Garrido
Funding agency: Col·legi Oficial d'Infermers/es de Barcelona
Funding: 1749
Reference: PR-593/2023
Duration: 01/01/2024 - 31/12/2025

Publications

Physiotherapy for patients on extracorporeal membrane oxygenation support: How, When, and Who. An international EuroELSO survey.

PMID: 36239077
Journal: PERFUSION-UK
Year: 2024
Reference: Perfusion. 2024 Jan;39(1):162-173. doi: 10.1177/02676591221133657. Epub 2022 Oct 14.
Impact factor:
Publication type: Paper in international publication
Authors: Antonini, Marta Velia; Barrett, Nicholas A; Dell'Amore, Andrea; Eden, Allaina; Loforte, Antonio; Polastri, Massimiliano; Riera, Jordi; Swol, Justyna et al.
DOI: 10.1177/02676591221133657

Hyperoxemia in invasively ventilated COVID-19 patients-Insights from the PRoVENT-COVID study.

PMID: 36274046
Journal: Pulmonology
Year: 2024
Reference: Pulmonology. 2024 May-Jun;30(3):272-281. doi: 10.1016/j.pulmoe.2022.09.003. Epub 2022 Sep 15.
Impact factor:
Publication type: Paper in international publication
Authors: Botta, M; Neto, A S; Paulus, F; Roca, O; Schultz, M J; Shrestha, G S; Tsonas, A M; van Meenen, D M et al.
DOI: 10.1016/j.pulmoe.2022.09.003

Extracorporeal membrane oxygenation in Jehovah's Witness patients: Case report, literature review, and summary of recommendations.

PMID: 34554022
Journal: PERFUSION-UK
Year: 2024
Reference: Perfusion. 2024 Jan;39(1):60-65. doi: 10.1177/02676591211047774. Epub 2021 Sep 23.
Impact factor:
Publication type: Paper in international publication
Authors: Argudo, Eduard; Bonilla, Camilo; Chiscano, Luis; Gallart, Elisabet; Lozano, Beatriz; Marin, Gemma; Martinez-Martinez, Maria; Mera, Abrahan; Pacheco, Andres; Palmada, Clara et al.
DOI: 10.1177/02676591211047774

Catastrophic Streptococcus pyogenes Disease: A Personalized Approach Based on Phenotypes and Treatable Traits.

PMID: 38391573
Journal: Antibiotics-Basel
Year: 2024
Reference: Antibiotics (Basel). 2024 Feb 15;13(2):187. doi: 10.3390/antibiotics13020187.
Impact factor:
Publication type: Paper in international publication
Authors: Bajana, Ivan; Bastidas, Juliana; Chiscano-Camon, Luis; Ferrer, Ricard; Franco-Jarava, Clara; Gonzalez-Lopez, Juan Jose; Larrosa, Nieves; Lopez-Martinez, Rocio; Maldonado, Carolina; Martin, Laura et al.
DOI: 10.3390/antibiotics13020187

Hyperglycemia in Acute Critically Ill COVID-19 Patients.

PMID: 36167740
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2023
Reference: Arch Bronconeumol. 2023 Jan;59(1):51-56. doi: 10.1016/j.arbres.2022.09.001. Epub 2022 Sep 9.
Impact factor:
Publication type: Letter whit IF
Authors: Barbe, Ferran; Cilloniz, Catia; de Gonzalo-Calvo, David; Fernandez-Barat, Laia; Ferrer, Ricard; Gabarrus, Albert; Garcia-Gasulla, Dario; Lorente, Jose Angel; Menendez, Rosario; Motos, Anna et al.
DOI: 10.1016/j.arbres.2022.09.001

In-hospital and 6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study.

PMID: 36402148
Journal: Lancet Respiratory Medicine
Year: 2023
Reference: Lancet Respir Med. 2023 Feb;11(2):151-162. doi: 10.1016/S2213-2600(22)00403-9. Epub 2022 Nov 16.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Shakra, Anas; Afukov, Ivan; Agnew, Nicola; Agnoletti, Vanni; Agus, Gianluca; Aigner, Tobias; Ajrhourh, Lucrezia; Akhyari, Payam; Albacete Moreno, Carlos L; Alcalde, Immaculada et al.
DOI: 10.1016/S2213-2600(22)00403-9

Effects of intubation timing in patients with COVID-19 throughout the four waves of the pandemic: a matched analysis.

PMID: 36396142
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2023
Reference: Eur Respir J. 2023 Mar 2;61(3):2201426. doi: 10.1183/13993003.01426-2022. Print 2023 Mar.
Impact factor:
Publication type: Paper in international publication
Authors: Adell-Serrano, Berta; Aguilera, Luciano; Amaya-Villar, Rosario; Anon, Jose Manuel; Barbe, Ferran; Barbera, Carme; Barberan, Jose; Barbeta, Enric; Blandino, Aaron; Boado, Maria Victoria et al.
DOI: 10.1183/13993003.01426-2022

Diagnosis of pneumonia: A shared need.

PMID: 36344417
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2023
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2023 Jan;41(1):57-58. doi: 10.1016/j.eimce.2022.10.009. Epub 2022 Nov 4.
Impact factor:
Publication type: Letter or abstract
Authors: Eiros, Jose Maria; Ferrer, Ricard; Mestre-Ferrandiz, Jorge; Torres, Antoni et al.
DOI: 10.1016/j.eimce.2022.10.009

Global Emergence of Resistance to Fluconazole and Voriconazole in Candida parapsilosis in Tertiary Hospitals in Spain During the COVID-19 Pandemic.

PMID: 36467290
Journal: Open Forum Infectious Diseases
Year: 2022
Reference: Open Forum Infect Dis. 2022 Nov 7;9(11):ofac605. doi: 10.1093/ofid/ofac605. eCollection 2022 Nov.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Sanchez, Maria-Mercedes; Alcazar-Fuoli, Laura; Alcoceba, Eva; Ardanuy-Tisaire, Carmen; Ayats-Ardite, Josefina; Carballo-Gonzalez, Cristina; Collazos-Blanco, Ana; de Ayala, Ana Perez; Duran-Valle, Maria Teresa; Escribano, Pilar et al.
DOI: 10.1093/ofid/ofac605

Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock.

PMID: 36459524
Journal: PLoS One
Year: 2022
Reference: PLoS One. 2022 Dec 2;17(12):e0278708. doi: 10.1371/journal.pone.0278708. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Bajana, Ivan; Canela, Nuria; Chiscano-Camon, Luis; Ferrer, Ricard; Gonzalez, Juan Jose; Larrosa, Nieves; Palmada, Clara; Ribas, Vicent; Ruiz-Rodriguez, Juan Carlos; Ruiz-Sanmartin, Adolfo et al.
DOI: 10.1371/journal.pone.0278708

Satisfaction of intensive care unit patients linked to clinical and organisational factors: A cross-sectional multicentre study.

PMID: 36456425
Journal: Australian Critical Care
Year: 2022
Reference: Aust Crit Care. 2022 Nov 28:S1036-7314(22)00226-0. doi: 10.1016/j.aucc.2022.10.013.
Impact factor:
Publication type: Paper in international publication
Authors: Adamuz-Tomas, Jordi; Alcala-Jimenez, Isidro; Benito-Aracil, Llucia; Cuzco, Cecilia; de la Cueva-Ariza, Laura; Delgado-Hito, Pilar; Martinez-Momblan, Maria Antonia; Romero-Garcia, Marta et al.
DOI: 10.1016/j.aucc.2022.10.013

Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines.

PMID: 36443794
Journal: Genome Medicine
Year: 2022
Reference: Genome Med. 2022 Nov 29;14(1):134. doi: 10.1186/s13073-022-01137-4.
Impact factor:
Publication type: Paper in international publication
Authors: Ballestar, Esteban; Barmada, Anis; Ciudad, Laura; de la Calle-Fabregat, Carlos; Ferrer, Ricard; Ferrete-Bonastre, Anna G; Godoy-Tena, Gerard; Martinez-Gallo, Monica; Martins-Ferreira, Ricardo; Morante-Palacios, Octavio et al.
DOI: 10.1186/s13073-022-01137-4

[Reply to "Considerations on ICU triage ethics during the COVID-19 pandemic"].

PMID: 34629589
Journal: Medicina Intensiva
Year: 2021
Reference: Med Intensiva. 2021 Aug-Sep;45(6):382. doi: 10.1016/j.medin.2020.07.001. Epub 2020 Jul 19.
Impact factor:
Publication type: Letter or abstract
Authors: Cabre, L; Estella, A; Ferrer, R; Rubio, O et al.
DOI: 10.1016/j.medin.2020.07.001

Mapping the human genetic architecture of COVID-19.

PMID: 34237774
Journal: NATURE
Year: 2021
Reference: Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelrazik, Marwa; Abdullah, Tala; Abe, Ryuzo; Abe, Shinji; Abecasis, Goncalo R; Abel, Lynn; Abernathy, Caroline; Abraheem, Azmerelda; Abul-Husn, Noura S; Acosta-Herrera, Marialbert et al.
DOI: 10.1038/s41586-021-03767-x

[A systematic review and expert's analysis of risk factors of infections in adults due to carbapenem-resistant Pseudomonas aeruginosa or Acinetobacter baumannii in Spain].

PMID: 33913312
Journal: Revista Espanola de Quimioterapia
Year: 2021
Reference: Rev Esp Quimioter. 2021 Aug;34(4):298-307. doi: 10.37201/req/034.2021. Epub 2021 Apr 29.
Impact factor:
Publication type: Review in national publication
Authors: Badía, X; Cantón, R; Del Pozo, J L; Ferrer, R; García-Vidal, C; Garnacho-Montero, J; Larrosa, N; Pellicer, B; Pintado, V; Rascado, P et al.
DOI: 10.37201/req/034.2021

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

PMID: 34597274
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2021
Reference: J Clin Invest. 2021 Dec 1;131(23). pii: 152386. doi: 10.1172/JCI152386.
Impact factor:
Publication type: Paper in international publication
Authors: Aarberg Lund, Kristine Marie; Aarem, Jeanette; Aballi, Saad; Abdullah, Tala; Adeleye, Olumide; Adra, Darin; Afilalo, Jonathan; Afilalo, Marc; Afrasiabi, Zaman; Aghemo, Alessio et al.
DOI: 10.1172/JCI152386

[Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection].

PMID: 34629620
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Jul;56:11-18. doi: 10.1016/j.arbres.2020.03.005. Epub 2020 Mar 30.
Impact factor:
Publication type: Paper in national publication
Authors: Carratala Perales, Jose Manuel; Cinesi Gomez, Cesar; de Andres Nilsson, Jose M; de Haro Lopez, Candelaria; Egea Santaolalla, Carlos; Farrero Munoz, Eva; Ferrando Ortola, Carlos; Ferrer Monreal, Miquel; Ferrer Roca, Ricard; Garcia Fernandez, Javier et al.
DOI: 10.1016/j.arbres.2020.03.005

Impact of simulation-based teamwork training on COVID-19 distress in healthcare professionals.

PMID: 33349248
Journal: BMC Medical Education
Year: 2020
Reference: BMC Med Educ. 2020 Dec 21;20(1):515. doi: 10.1186/s12909-020-02427-4.
Impact factor:
Publication type: Paper in international publication
Authors: Arnedo, Mireia; Beneria, Anna; Contreras, Sofia; Garcia-Ruiz, Itziar; Perez-Carrasco, Marco; Radua, Joaquim; Rius, Jordi Baneras; Rodriguez-Carballeira, Monica et al.
DOI: 10.1186/s12909-020-02427-4

Capping or Suctioning for Tracheostomy Decannulation. Reply.

PMID: 33326726
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2020
Reference: N Engl J Med. 2020 Dec 17;383(25):2481. doi: 10.1056/NEJMc2031385.
Impact factor:
Publication type: Letter or abstract
Authors: Colinas, Laura; Hernandez Martinez, Gonzalo; Roca, Oriol et al.
DOI: 10.1056/NEJMc2031385

Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19.

PMID: 33317616
Journal: CRITICAL CARE
Year: 2020
Reference: Crit Care. 2020 Dec 14;24(1):691. doi: 10.1186/s13054-020-03398-0.
Impact factor:
Publication type: Paper in international publication
Authors: Abadia, Jesica; Aldecoa, Cesar; Almansa, Raquel; Barbe, Ferran; Berezo, Jose Angel; Bermejo-Martin, Jesus F; Blanca-Lopez, Natalia; Blanco, Jesus; Bustamante, Elena; Bustamante-Munguira, Juan et al.
DOI: 10.1186/s13054-020-03398-0

MONOGRÁFICO: ANTISEPSIA EN EL PACIENTE CRÍTICO: Introducción.

PMID: 30366680
Journal: Medicina Intensiva
Year: 2019
Reference: Medicina Intensiva. 2019 Mar;43:1. doi: 10.1016/j.medin.2018.07.018.
Impact factor:
Publication type: Paper in national publication
Authors: Diaz, E; Nuvials, X; Ramirez, P et al.
DOI: 10.1016/j.medin.2018.07.018

Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study.

PMID: 30790030
Journal: INTENSIVE CARE MEDICINE
Year: 2019
Reference: Intensive Care Med. 2019 May;45(5):592-600. doi: 10.1007/s00134-019-05567-4. Epub 2019 Feb 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alessandri, Francesco; Antonelli, Massimo; Beale, Richard; Brochard, Laurent; Brodie, Daniel; Capelier, Gilles; Chiche, Jean-Daniel; Combes, Alain; de Backer, Daniel; Diehl, Jean-Luc et al.
DOI: 10.1007/s00134-019-05567-4

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.

PMID: 31104069
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 May 28;321(20):1993-2002. doi: 10.1001/jama.2019.5358.
Impact factor:
Publication type: Paper in international publication
Authors: Barie, Philip S; Crowther, Mark; Daga, Mradul Kumar; Esmon, Charles T; Fareed, Jawed; Ferrer Roca, Ricard; Fineberg, David; Francois, Bruno; Gando, Satoshi; Gorelick, Kenneth J et al.
DOI: 10.1001/jama.2019.5358

An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High Flow Therapy.

PMID: 30576221
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2019
Reference: Am J Respir Crit Care Med. 2019 Jun 1;199(11):1368-1376. doi: 10.1164/rccm.201803-0589OC.
Impact factor:
Publication type: Paper in international publication
Authors: Caralt, Berta; Frat, Jean-Pierre; Garcia-de-Acilu, Marina; Hernandez, Gonzalo; Masclans, Joan R; Messika, Jonathan; Ricard, Jean-Damien; Roca, Oriol; Samper, Manuel; Sztrymf, Benjamin et al.
DOI: 10.1164/rccm.201803-0589OC

Surviving Sepsis Campaign: Research Priorities for Sepsis and Septic Shock.

PMID: 29957716
Journal: CRITICAL CARE MEDICINE
Year: 2018
Reference: Crit Care Med. 2018 Aug;46(8):1334-1356. doi: 10.1097/CCM.0000000000003225.
Impact factor:
Publication type: Paper in international publication
Authors: Antonelli, Massimo; Coopersmith, Craig M; De Backer, Daniel; Deutschman, Clifford S; Evans, Laura E; Ferrer, Ricard; Hellman, Judith; Jog, Sameer; Kesecioglu, Jozef; Lat, Ishaq et al.
DOI: 10.1097/CCM.0000000000003225

Improving knowledge about sepsis 3 definition in critically ill patients: new insights

PMID: NOPMID042
Journal: Journal of Emergency and Critical Care Medicine
Year: 2018
Reference: Improving knowledge about sepsis 3 definition in critically ill patients: new insights. J Emerg Crit Care Med. 2018;2(4)
Impact factor:
Publication type: Editorail in international publication
Authors: Ferrer Roca, Ricard; Martínez, María Luisa; Ruiz Rodriguez, Juan Carlos et al.
DOI: 10.21037/jeccm.2018.04.05

Respiratory support therapy after extubation: Who and how?

PMID: 29122291
Journal: Medicina Intensiva
Year: 2018
Reference: Med Intensiva. 2018 May;42(4):255-257. doi: 10.1016/j.medin.2017.09.005. Epub 2017 Nov 6.
Impact factor:
Publication type: Review in international publication
Authors: Hernandez, G; Roca, O et al.
DOI: 10.1016/j.medin.2017.09.005

Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).

PMID: 29632995
Journal: INTENSIVE CARE MEDICINE
Year: 2018
Reference: Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9.
Impact factor:
Publication type: Paper in international publication
Authors: Achtzehn, Ute; Almirall, Jordi; Alvarez-Lerma, Francisco; Artigas, Antonio; Belohradsky, Bernd H; Bobenhausen, Iris; Bonastre Mora, Juan; Brealey, David; Brederlau, Jorg; Dalken, Benjamin et al.
DOI: 10.1007/s00134-018-5143-7

Toward a personalized response approach in sepsis 4.0.

PMID: 27609495
Journal: Medicina Intensiva
Year: 2017
Reference: Med Intensiva. 2017 Jan - Feb;41(1):55-56. doi: 10.1016/j.medin.2016.06.005. Epub 2016 Sep 5.
Impact factor:
Publication type: Letter whit IF
Authors: Artigas, A; de Haro, C; Ferrer, R; Martin-Loeches, I; Rodriguez, A; Torrents, E et al.
DOI: 10.1016/j.medin.2016.06.005

Impact of Source Control in Patients With Severe Sepsis and Septic Shock.

PMID: 27611975
Journal: CRITICAL CARE MEDICINE
Year: 2017
Reference: Crit Care Med. 2017 Jan;45(1):11-19. doi: 10.1097/CCM.0000000000002011.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Rocha, Luis; Artigas, Antonio; Ferrer, Ricard; Goma, Gemma; Guillamat-Prats, Raquel; Levy, Mitchell M; Martin-Loeches, Ignacio; Martinez, Maria Luisa; Pozo Laderas, Juan Carlos; Suarez, David et al.
DOI: 10.1097/CCM.0000000000002011

Declining mortality due to severe sepsis and septic shock in Spanish intensive care units: A two-cohort study in 2005 and 2011.

PMID: 28029501
Journal: Medicina Intensiva
Year: 2017
Reference: Med Intensiva. 2017 Jan - Feb;41(1):28-37. doi: 10.1016/j.medin.2016.09.004. Epub 2016 Oct 28.
Impact factor:
Publication type: Paper in national publication
Authors: Artigas, A; Ferrer, R; Goma, G; Martinez, M L; Piacentini, E; Romay, E; Sanchez, B; Suarez, D et al.
DOI: 10.1016/j.medin.2016.09.004

Impact of a multifaceted educational intervention including serious games to improve the management of invasive candidiasis in critically ill patients.

PMID: 27645566
Journal: Medicina Intensiva
Year: 2017
Reference: Med Intensiva. 2017 Jan - Feb;41(1):3-11. doi: 10.1016/j.medin.2016.07.003. Epub 2016 Sep 16.
Impact factor:
Publication type: Paper in national publication
Authors: Ferrer, R; Llinares, P; Maseda, E; Quindos, G; Rodriguez, A; Zaragoza, R et al.
DOI: 10.1016/j.medin.2016.07.003

Erratum to: The Intensive Care Global Study on Severe Acute Respiratory Infection (ICGLOSSARI): a multicenter, multinational, 14-day inception cohort study.

PMID: 27038479
Journal: INTENSIVE CARE MEDICINE
Year: 2016
Reference: Intensive Care Med. 2016 May;42(5):953. doi: 10.1007/s00134-016-4317-4.
Impact factor:
Publication type: Letter or abstract
Authors: Beale, Richard; Brochard, Laurent; Chiche, Jean Daniel; Ferrer, Ricard; Moreno, Rui; Reinhart, Konrad; Rezende, Ederlon; Rhodes, Andrew; Sakr, Yasser; Thompson, B Taylor et al.
DOI: 10.1007/s00134-016-4317-4

Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines.

PMID: 26723563
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2016
Reference: Clin Microbiol Infect. 2016 Apr;22(4):359-364. doi: 10.1016/j.cmi.2015.12.016. Epub 2015 Dec 23.
Impact factor:
Publication type: Paper in international publication
Authors: Bassetti, M; Blot, S; Chastre, J; Felton, T; Luyt, C-E; Palmer, L B; Pereira, J M; Poulakou, G; Qiu, H; Rello, J et al.
DOI: 10.1016/j.cmi.2015.12.016

Influenza A virus infection is associated with systemic capillary leak syndrome: case report and systematic review of the literature.

PMID: 26330157
Journal: ANTIVIRAL THERAPY
Year: 2016
Reference: Antivir Ther. 2016;21(2):181-3. doi: 10.3851/IMP2989. Epub 2015 Sep 2.
Impact factor:
Publication type: Review in international publication
Authors: Almirante, Benito; Escola, Laura; Len, Oscar; Magnifico, Bruno; Mora, Chema; Papiol, Elisabeth; Revilla, Eva; Sousa, Adrian et al.
DOI: 10.3851/IMP2989

Primary Graft Dysfunction and Mortality Following Lung Transplantation: A Role for Proadrenomedullin Plasma Levels.

PMID: 26461449
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2016
Reference: Am J Transplant. 2016 Feb;16(2):634-9. doi: 10.1111/ajt.13478. Epub 2015 Oct 13.
Impact factor:
Publication type: Paper in international publication
Authors: Baldira, Jaume; Bello, Irene; Berastegui, Cristina; Bravo, Carlos; Canela, Mercedes; Cubero, M; Deu, Maria; Gavalda, Joan; Jauregui, Alberto; Lagunes, Leonel et al.
DOI: 10.1111/ajt.13478

[Littoral cell angioma. An uncommon cause of constitutional syndrome].

PMID: 25070519
Journal: MED CLIN-BARCELONA
Year: 2015
Reference: Med Clin (Barc). 2015 Mar 9;144(5):239. doi: 10.1016/j.medcli.2014.04.019. Epub 2014 Jul 26.
Impact factor:
Publication type: Letter or abstract
Authors: Callejas Moraga, Eduardo L; Pinal Fernandez, Iago; Roade Tato, Luisa; Santafe Colomina, Manel et al.
DOI: 10.1016/j.medcli.2014.04.019

The Role of Omega-3 Polyunsaturated Fatty Acids in the Treatment of Patients with Acute Respiratory Distress Syndrome: A Clinical Review.

PMID: 26339627
Journal: BIOMED RES INT
Year: 2015
Reference: Biomed Res Int. 2015;2015:653750. doi: 10.1155/2015/653750. Epub 2015 Aug 3.
Impact factor:
Publication type: Review in international publication
Authors: Caralt, B; Garcia de Acilu, M; Leal, S; Masclans, J R; Roca, O; Sabater, J et al.
DOI: 10.1155/2015/653750

Interfaces in non-invasive ventilation: one mask doesn't fit all.

PMID: 25479471
Journal: MINERVA ANESTESIOL
Year: 2015
Reference: Minerva Anestesiol. 2015 May;81(5):478-9. Epub 2014 Dec 5.
Impact factor:
Publication type: Paper in national publication
Authors: Masclans, J R; Roca, O et al.
DOI:

Humidified High Flow Nasal Cannula Supportive Therapy Improves Outcomes in Lung Transplant Recipients Readmitted to the Intensive Care Unit Because of Acute Respiratory Failure.

PMID: 25340596
Journal: TRANSPLANTATION
Year: 2015
Reference: Transplantation. 2015 May;99(5):1092-8. doi: 10.1097/TP.0000000000000460.
Impact factor:
Publication type: Paper in international publication
Authors: Caballero, Jesus; Caralt, Berta; de Acilu, Marina Garcia; Masclans, Joan R; Roca, Oriol; Ruiz, Adolf; Ruiz, Juan Carlos; Sacanell, Judit; Serra, Joaquim et al.
DOI: 10.1097/TP.0000000000000460

Cerebral aspergillosis in adult critically ill patients: a descriptive report of 10 patients from the AspICU cohort.

PMID: 24315314
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2014
Reference: Int J Antimicrob Agents. 2014 Feb;43(2):165-9. doi: 10.1016/j.ijantimicag.2013.10.012. Epub 2013 Nov 15.
Impact factor:
Publication type: Paper in international publication
Authors: Blasco-Navalpotro, Miguel; Blot, Stijn; Blot, Stijn I; Brusselaers, Nele; Bulpa, Pierre; Cardoso, Teresa; Charles, Pierre-Emmanuel; Charles, Pierre-Emmanuel; Clause, Didier; Courouble, Patricia et al.
DOI: 10.1016/j.ijantimicag.2013.10.012

Bilastine vs. hydroxyzine: occupation of brain histamine H1 -receptors evaluated by positron emission tomography in healthy volunteers.

PMID: 24833043
Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2014
Reference: Br J Clin Pharmacol. 2014 Nov;78(5):970-80. doi: 10.1111/bcp.12421.
Impact factor:
Publication type: Clinical guide
Authors: Bullich, Santiago; Farre, Magi; Herance, Jose-Raul; Labeaga, Luis; Martin, Soraya; Menoyo, Esther; Papaseit, Esther; Perez, Marta; Perez-Mana, Clara; Rojas, Santiago et al.
DOI: 10.1111/bcp.12421

[Empirical antimicrobial therapy in ICU admitted patients. Influence of microbiological confirmation on the length of treatment].

PMID: 25536429
Journal: Revista Espanola de Quimioterapia
Year: 2014
Reference: Rev Esp Quimioter. 2014 Dec;27(4):252-60.
Impact factor:
Publication type: Paper in national publication
Authors: Alcaraz, R; Arnau, E; Caballero, J; Laborda, C; Larrosa, M N; Nuvials, X; Palomar, M; Perez, M; Serra, J et al.
DOI:

Impact of prompt catheter withdrawal and adequate antimicrobial therapy on the prognosis of hospital-acquired parenteral nutrition catheter-related bacteraemia.

PMID: 24888250
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2014
Reference: Clin Microbiol Infect. 2014 Nov;20(11):1205-10. doi: 10.1111/1469-0691.12703. Epub 2014 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alcaraz, R; Almirante, B; Burgos, R; Fernandez-Hidalgo, N; Ferrer, C; Pahissa, A; Pigrau, C; Planes, A M; Rodriguez-Pardo, D et al.
DOI: 10.1111/1469-0691.12703

Effect of High Flow Nasal Cannula and Body Position on End-Expiratory Lung Volume. A Cohort Study Using Electrical Impedance Tomography.

PMID: 23050520
Journal: Respiratory Care
Year: 2013
Reference: Respir Care. 2013 Apr;58(4):589-96. doi: 10.4187/respcare.02086.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes, Jordi; Masclans, Joan Ramon; Perez, Purificacion; Rello, Jordi; Riera, Jordi; Roca, Oriol et al.
DOI: 10.4187/respcare.02086

EPICO PROJECT. Development of educational recommendations using the DELPHI technique on invasive candidiasis in non- neutropenic critically ill adult patients.

PMID: 23817652
Journal: Revista Espanola de Quimioterapia
Year: 2013
Reference: Rev Esp Quimioter. 2013 Jun;26(2):131-50.
Impact factor:
Publication type: Paper in national publication
Authors: Aguado Garcia, Jose Maria; Aguilar Aguilar, Gerardo; Alcala Llorente, Miguel Angel; Aldecoa, Cesar; Almirante Guajedo, Benito; Alvarez Lerma, Francisco; Alvarez Lerma, Francisco; Anton Pascual, Jose Luis; Aragon Gonzalez, Cesar; Aragon Gonzalez, Cesar et al.
DOI:

Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "Seville Document".

PMID: 23867181
Journal: Blood Transfusion
Year: 2013
Reference: Blood Transfus. 2013 Oct;11(4):585-610. doi: 10.2450/2013.0029-13. Epub 2013 Jun 17.
Impact factor:
Publication type: Paper in international publication
Authors: Asuero, Marisol; Asuero, Marisol; Basora, Misericordia; Bautista-Paloma, Francisco Jose; Bisbe, Elvira; Boveda, Jose Luis; Castillo-Munoz, Auxiliadora; Colomina, Maria Jose; Contreras, Enric; Contreras, Enric et al.
DOI: 10.2450/2013.0029-13

Human Mesenchymal Stem Cells Overexpressing the IL-33 Antagonist Soluble IL-1 Receptor-Like-1 Attenuate Endotoxin-Induced Acute Lung Injury.

PMID: 23656573
Journal: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Year: 2013
Reference: Am J Respir Cell Mol Biol. 2013 Oct;49(4):552-62. doi: 10.1165/rcmb.2012-0406OC.
Impact factor:
Publication type: Paper in international publication
Authors: Aran, Josep M; Baekelandt, Veerle; Cruz, Maria J; Martinez-Gonzalez, Itziar; Masclans, Joan R; Moreno, Rafael; Rello, Jordi; Roca, Oriol; Salcedo, Maria T et al.
DOI: 10.1165/rcmb.2012-0406OC

Antibiotic prescription patterns in the empirical therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality.

PMID: 23158399
Journal: CRITICAL CARE
Year: 2012
Reference: Crit Care. 2012 Nov 18;16(6):R223. doi: 10.1186/cc11869.
Impact factor:
Publication type: Paper in international publication
Authors: Artigas, Antoni; Diaz-Martin, Ana; Ferrer, Ricard; Garnacho-Montero, Jose; Levy, Mitchell M; Lopez-Pueyo, Maria J; Martin-Loeches, Ignacio; Martinez-Gonzalez, Maria L; Ortiz-Leyba, Carlos; Piacentini, Enrique et al.
DOI: 10.1186/cc11869

Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study.

PMID: 22301068
Journal: Medicina Intensiva
Year: 2012
Reference: Med Intensiva. 2012 May;36(4):257-63. Epub 2012 Feb 1.
Impact factor:
Publication type: Paper in national publication
Authors: Almansa, R; Bermejo-Martin, J F; Lopez-Campos, G; Martin-Loeches, I; Papiol, E; Rello, J et al.
DOI: 10.1016/j.medin.2011.10.009

Solid organ transplant training objectives for residents.

PMID: 22980670
Journal: Medicina Intensiva
Year: 2012
Reference: Med Intensiva. 2012 Nov;36(8):584-8. doi: 10.1016/j.medin.2012.03.012. Epub 2012 Sep 13.
Impact factor:
Publication type: Paper in national publication
Authors: Ballesteros, M A; Masclans, J R; Rello, J; Roca, O; Sabater, J; Vicente, R et al.
DOI: 10.1016/j.medin.2012.03.012

Mortality after surgery in Europe: a 7 day cohort study.

PMID: 22998715
Journal: LANCET
Year: 2012
Reference: Lancet. 2012 Sep 22;380(9847):1059-65. doi: 10.1016/S0140-6736(12)61148-9.
Impact factor:
Publication type: Paper in international publication
Authors: ; Aakeroey, Kristin; Acan, Ivana; Adams, David; Adams, Tim; Adanic, Mirta; Adolfsson, Anne; Afonso, Ofelia; Afshari, Arash; Agarwal, Banwari et al.
DOI: 10.1016/S0140-6736(12)61148-9

Severe sepsis mortality prediction with relevance vector machines.

PMID: 22254260
Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Year: 2011
Reference: Conf Proc IEEE Eng Med Biol Soc. 2011;2011:100-3.
Impact factor:
Publication type: Letter or abstract
Authors: Lopez, Jesus Caballero; Rello, Jordi; Ribas, Vicent J; Ruiz-Rodriguez, Juan Carlos; Ruiz-Sanmartin, Adolf; Vellido, Alfredo; Wojdel, Anna et al.
DOI: 10.1109/IEMBS.2011.6089906

Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients.

PMID: 22126648
Journal: CRITICAL CARE
Year: 2011
Reference: Crit Care. 2011;15(6):R286. doi: 10.1186/cc10573. Epub 2011 Nov 28.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/cc10573

Combination antibiotic therapy for community-acquired pneumonia.

PMID: 22113077
Journal: Annals of intensive care
Year: 2011
Reference: Ann Intensive Care. 2011 Nov 23;1:48. doi: 10.1186/2110-5820-1-48.
Impact factor:
Publication type: Letter or abstract
Authors: ; et al.
DOI: 10.1186/2110-5820-1-48

CD4+ cell counts and HIV-RNA levels do not predict outcomes of community-acquired pneumonia in hospitalized HIV-infected patients.

PMID: 21885316
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2011
Reference: Int J Infect Dis. 2011 Dec;15(12):e822-7. Epub 2011 Aug 31.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.ijid.2011.05.021

[Mortality risk factors in descending necrotizing mediastinitis].

PMID: 20227809
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2010
Reference: Arch Bronconeumol. 2010 Apr;46(4):182-7. doi: 10.1016/j.arbres.2010.01.008. Epub 2010 Mar 15.
Impact factor:
Publication type: Paper in national publication
Authors: Alcaraz Penarrocha, Rosa; Deu-Martin, Maria; Lopez Sanz, Iker; Romero Vielva, Laura; Saez-Barba, Manel; Sole Montserrat, Joan et al.
DOI: 10.1016/j.arbres.2010.01.008

[Primary decompressive craniectomy in patients with aneurysmatic subarachnoid hemorrhage. Results of a pilot study in 11 cases.]

PMID: 21165542
Journal: NEUROCIRUGIA
Year: 2010
Reference: Neurocirugia (Astur). 2010 Dec;21(6):452-460.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; ; et al.
DOI:

High-flow oxygen therapy in acute respiratory failure.

PMID: 20406507
Journal: Respiratory Care
Year: 2010
Reference: Respir Care. 2010 Apr;55(4):408-13.
Impact factor:
Publication type: Paper in international publication
Authors: Masclans, Joan R; Riera, Jordi; Roca, Oriol; Torres, Ferran et al.
DOI:

Broadening horizons: research priorities in pneumonia.

PMID: 20562546
Journal: CRITICAL CARE MEDICINE
Year: 2010
Reference: Crit Care Med. 2010 Jul;38(7):1602-3.
Impact factor:
Publication type: Editorail in international publication
Authors: Perez, Marcos; Rello, Jordi; Sanchez, Ana et al.
DOI: 10.1097/CCM.0b013e3181e4bafa

Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study.

PMID: 19696442
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2009
Reference: Am J Respir Crit Care Med. 2009 Nov 1;180(9):861-6.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Maria; Ambros, Alfonso; Anon, Jose Maria; Antuna, Maria Teresa; Aranjo, Juan B; Arenzana, Angel; Arenzana, Angel; Artigas, Antonio; Artigas, Antonio; Ayestaran, Jose Ignacio et al.
DOI: 10.1164/rccm.200812-1912OC

Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study.

PMID: 19696442
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2009
Reference: Am J Respir Crit Care Med. 2009 Nov 1;180(9):861-6.
Impact factor: 9.792
Publication type: Paper in international publication
Authors: de la Torre, Maria Victoria, Ferrer, Ricard, Artigas, Antonio, Suarez, David, Palencia, Eduardo, Levy, Mitchell M, Arenzana, Angel, Perez, Xose Luis, Sirvent, Josep-Maria, Goma, Gemma et al.
DOI: 10.1164/rccm.200812-1912OC

Thesis

Prevalencia del delirium en el paciente crítico en UCI.

PhD student: Jesús Caballero López
Director/s: Ricard Ferrer Roca, Juan Carlos Ruiz Rodriguez
University: Universitat Autònoma de Barcelona
Year: 2023

Limitación del esfuerzo terapéutico en las Unidades de Cuidados Intensivos de Cataluña

PhD student: Alexandra Cortina Gutierrez, Alexandra Cortina Gutierrez
Director/s: Alberto Sandiumenge Camps, Xavier Nuvials Casals
University: Universidad Autònoma de Barcelona
Year: 2022

Infecciones respiratorias asociadas con la ventilación mecànica. Impacto en el uso de antimicrobianos

PhD student: Xavier Nuvials Casals, Xavier Nuvials Casals
Director/s: Mercedes Palomar Martínez
University: Universidad Autònoma de Barcelona
Year: 2016

Perspectivas en Trasplante de Pulmón

PhD student: Jordi Riera del Brío
Director/s: Teresa Pont Castellana, Jordi Rello Condomines
University: Universidad Autònoma de Barcelona
Year: 2015

Lesión endotelial en la disfunción multiorgánica de la sepsis grave

PhD student: Juan Carlos Ruiz Rodriguez
Director/s: Miguel Vilardell Tarres, Joaquín Serra Vich, Miguel Vilardell Tarres
University: Universidad Autònoma de Barcelona
Year: 2015

Influenza A(H1N1)pdm 2009. Papel de la Medicina Intensiva durante la Pandemia y Post-Pandemia

PhD student: Marcos Pérez Carrasco
Director/s: Joan Ramon Masclans Enviz, Ferran Morell Brotad, Ferran Morell Brotad
University: Universidad Autònoma de Barcelona
Year: 2015

Qualitat de vida i alteracions morfo-funcionals en supervivents a una Síndrome del Destret Respiratori Agut

PhD student: Oriol Roca Gas
Director/s: Joan Ramon Masclans Enviz, Fco. Javier Muñoz Gall
University: Universidad Autònoma de Barcelona
Year: 2010

Blog

News

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

Hybrids VITA, developed together with Medical Simulator, reproduces different clinical scenarios for training on how to prevent, diagnose and treat possible complications of ECMO, which is a very complex technique.

Extracorporeal Cardiopulmonary Resuscitation (ECPR) offers therapeutic options for patients in whom conventional cardiopulmonary resuscitation techniques fail to restore the heartbeat.