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Stroke Research

The search for quality and innovation has always been an inherent part of the activity of the Stroke Research Group and represents the common thread that leads us to excellence and continuous improvement.

In recent years, the Stroke Research Group has established itself as a leader in the management, recruitment and international coordination of multicenter clinical trials, as well as in the development of patents for new thrombectomy devices and the creation of new technological solutions and digital platforms to improve the diagnosis, treatment and follow-up of stroke patients. Robust strategic alliances have also been consolidated with public and private entities that ensure the viability and scalability of the research projects initiated in our group.

The Stroke Research Group is made up of a transversal and multidisciplinary team that shares a common idea: to contribute from its area of knowledge to the care and management of stroke through the effective transfer of knowledge and the complementarity of the processes of clinical research.

Team

Laia Sanchez i Trilles

Laia Sanchez i Trilles

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Laura Ludovica Gramegna .

Laura Ludovica Gramegna .

Research technician
Stroke research
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Li , Jiahui

Li , Jiahui

Research technician
Stroke research
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Magda Jablonska

Magda Jablonska

Postdoctoral researcher
Stroke research
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Maria Victoria Sala Sanz de Madrid

Maria Victoria Sala Sanz de Madrid

Administration and Management
Stroke research
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Miriam Correa Losada

Miriam Correa Losada

Research technician
Stroke research
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Laia Sanchez i Trilles

Laia Sanchez i Trilles

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Laura Ludovica Gramegna .

Laura Ludovica Gramegna .

Research technician
Stroke research
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Li , Jiahui

Li , Jiahui

Research technician
Stroke research
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Magda Jablonska

Magda Jablonska

Postdoctoral researcher
Stroke research
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Maria Victoria Sala Sanz de Madrid

Maria Victoria Sala Sanz de Madrid

Administration and Management
Stroke research
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Miriam Correa Losada

Miriam Correa Losada

Research technician
Stroke research
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Research lines

Innovation in clinical processes for cerebral reperfusion

Responsible: Dr. Carlos Molina

IP: -

Innovation in clinical research nursing processes in stroke

Responsible: Dra. Estela Sanjuan

IP: -

Innovation platforms in communication technology and telemedicine

Responsible: Dr. Marc Ribo

IP: -

Innovative designs and implementation of clinical trials in stroke

Responsible: Dr. Carlos Molina

IP: -

Projects

POC4TRIAGE: Point-of-Care Devices for Urgent Care Triage

IP: Carlos Molina Cateriano
Collaborators: Noelia Rodríguez Villatoro, Carole Conforti, David Rodriguez Luna
Funding agency: EUROPEAN COMMISSION
Funding: 672750
Reference: POC4TRIAGE_HE-HLTH2023
Duration: 01/07/2024 - 30/06/2028

Early identification of intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) and implications in endovascular treatment

IP: Marc Ribó Jacobi
Collaborators: Marc Rodrigo Gisbert
Funding agency: Fundació Institut de Recerca HUVH
Funding: 59681.19
Reference: DORADO/2024/RODRIGO
Duration: 08/06/2024 - 07/06/2026

BIOBANCOS Y BIOMODELOS

IP: Isabel Novoa Garcia
Collaborators: Joaquim Vives Armengol, Anna Duarri Piqué, Eva Colas Ortega, Oriol Bestard Matamoros, Marta Rosal Fontana, Carmen Espejo Ruiz, Marielle Esteves Coelho, Juan Jose Gonzalez Lopez, Sheyla Pascual Martín, Alejandro Tomasello Weitz, Shirley Guzmán Avilés
Funding agency: Instituto de Salud Carlos III
Funding: 137460
Reference: PT23/00040
Duration: 01/01/2024 - 31/12/2026

Aplicación de estrategias para agilizar el tratamiento de pacientes con ictus agudo

IP: Marc Ribó Jacobi
Collaborators: Marta Olive Gadea, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 65000
Reference: CM23/00280
Duration: 31/03/2024 - 30/03/2026

Publications

Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels.

PMID: 39908430
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2025
Reference: N Engl J Med. 2025 Feb 5. doi: 10.1056/NEJMoa2408954.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Angelika; Amaro, Sergio; Arenillas, Juan F; Balmer, Luzia; Bellante, Flavio; Bolognese, Manuel; Brehm, Alex; Buhk, Jan-Hendrik; Castano, Carlos; Coutinho, Jonathan M et al.
DOI: 10.1056/NEJMoa2408954

Clinical Results of the ANAIS Study: Mechanical Thrombectomy Using the ANA Device in Combination with a Stent Retriever in Subjects with Acute Ischemic Stroke.

PMID: 40037699
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2025
Reference: AJNR Am J Neuroradiol. 2025 Mar 4;46(3):502-509. doi: 10.3174/ajnr.A8556.
Impact factor:
Publication type: Paper in international publication
Authors: Bashir, Saima; Diana, Francesco; Diaz-Perez, Jose; Dios, Marta De; Galve, Inyaki; Gramegna, Laura Ludovica; Hernandez, David; Requena, Manuel; Ribo, Marc; Rivera, Eila et al.
DOI: 10.3174/ajnr.A8556

Clinico-radiological features of intracranial atherosclerosis-related large vessel occlusion prior to endovascular treatment.

PMID: 38316891
Journal: Scientific Reports
Year: 2024
Reference: Sci Rep. 2024 Feb 5;14(1):2945. doi: 10.1038/s41598-024-53354-z.
Impact factor:
Publication type: Paper in international publication
Authors: Bashir, Saima; De Dios Lascuevas, Marta; Garcia-Tornel, Alvaro; Hernandez, David; Juega, Jesus; Molina, Carlos A; Muchada, Marian; Olive-Gadea, Marta; Pagola, Jorge; Pinana, Carlos et al.
DOI: 10.1038/s41598-024-53354-z

Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study.

PMID: 38335240
Journal: STROKE
Year: 2024
Reference: Stroke. 2024 Feb 9. doi: 10.1161/STROKEAHA.123.045731.
Impact factor:
Publication type: Paper in international publication
Authors: Adams, Latasha; Affan, Muhammad; Aguiar de Sousa, Diana; Al Kasab, Sami; Ali, Farman; AlMajali, Mohammad; Alvarado-Bolanos, Alonso; Alvi, Muhammad; Amar, Jordan; Anadani, Mohammad et al.
DOI: 10.1161/STROKEAHA.123.045731

Enhancing blood pressure management protocol implementation in patients with acute intracerebral haemorrhage through a nursing-led approach: A retrospective cohort study.

PMID: 38379362
Journal: JOURNAL OF CLINICAL NURSING
Year: 2024
Reference: J Clin Nurs. 2024 Feb 20. doi: 10.1111/jocn.17080.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Garcia-Tornel, Alvaro; Minarro, Olga; Molina, Carlos A; Muchada, Marian; Olive-Gadea, Marta; Pancorbo, Olalla; Rodriguez-Luna, David; Rodriguez-Samaniego, Maria Teresa; Rodriguez-Villatoro, Noelia et al.
DOI: 10.1111/jocn.17080

Stroke-associated pneumonia according to mCDC criteria: impact on prognosis and antibiotic therapy.

PMID: 38497035
Journal: Frontiers in Neurology
Year: 2024
Reference: Front Neurol. 2024 Feb 28;15:1358628. doi: 10.3389/fneur.2024.1358628. eCollection 2024.
Impact factor:
Publication type: Paper in international publication
Authors: Alcahut-Rodriguez, Cristian; Alvarez-Larruy, Marta; Avellaneda, Carla; Bustamante, Alejandro; Dominguez-Mayoral, Ana; Dorado, Laura; Ezcurra-Diaz, Garbine; Faura, Julia; Fernandez-Perez, Isabel; Freijo, Mari Mar et al.
DOI: 10.3389/fneur.2024.1358628

Endovascular vs Medical Management for Late Anterior Large Vessel Occlusion With Prestroke Disability: Analysis of CLEAR and RESCUE-Japan.

PMID: 36332983
Journal: NEUROLOGY
Year: 2023
Reference: Neurology. 2023 Feb 14;100(7):e751-e763. doi: 10.1212/WNL.0000000000201543. Epub 2022 Nov 4.
Impact factor:
Publication type: Paper in international publication
Authors: Abdalkader, Mohamad; Caparros, Francois; Castonguay, Alicia; Cordonnier, Charlotte; Demeestere, Jelle; Farooqui, Mudassir; Farzin, Behzad; Fischer, Urs; Gutierrez, Santiago Ortega; Haussen, Diogo C et al.
DOI: 10.1212/WNL.0000000000201543

Intensive 90-day textile wearable Holter monitoring: an alternative to detect paroxysmal atrial fibrillation in selected patients with cryptogenic stroke.

PMID: 35882656
Journal: HEART AND VESSELS
Year: 2023
Reference: Heart Vessels. 2023 Jan;38(1):114-121. doi: 10.1007/s00380-022-02141-9. Epub 2022 Jul 27.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Arenillas, Juan F; Boned, Sandra; Cabezas, Juan Antonio; De Lera-Alfonso, Mercedes; de Torres, Reyes; Deck, Matias; Dorado, Laura; Francisco-Pascual, Jaume; Garcia-Tornel, Alvaro et al.
DOI: 10.1007/s00380-022-02141-9

Remote Training of Neurointerventions by Audiovisual Streaming : Experiences from the European ESMINT-EYMINT E-Fellowship Program.

PMID: 35829740
Journal: Clinical Neuroradiology
Year: 2023
Reference: Clin Neuroradiol. 2023 Mar;33(1):137-145. doi: 10.1007/s00062-022-01192-9. Epub 2022 Jul 13.
Impact factor:
Publication type: Paper in international publication
Authors: Andersson, Tommy; Bechstein, Matthias; Boccardi, Edoardo; Boulouis, Gregoire; Broocks, Gabriel; Chapot, Rene; Cognard, Christophe; Daller, Cornelia; de Dios Lascuevas, Marta; Fiehler, Jens et al.
DOI: 10.1007/s00062-022-01192-9

Combined technique as first approach in mechanical thrombectomy: Efficacy and safety of REACT catheter combined with stent retriever.

PMID: 35491662
Journal: INTERVENTIONAL NEURORADIOLOGY
Year: 2023
Reference: Interv Neuroradiol. 2023 Oct;29(5):504-509. doi: 10.1177/15910199221095798. Epub 2022 May 2.
Impact factor:
Publication type: Paper in international publication
Authors: Boned, Sandra; Cuevas, Jose Luis; De Dios, Marta; Garcia-Tornel, Alvaro; Gramegna, Laura Ludovica; Hernandez, David; Molina, Carlos; Muchada, Marian; Olive-Gadea, Marta; Pinana, Carlos et al.
DOI: 10.1177/15910199221095798

Monocyte-to-Lymphocyte Ratio in Clot Analysis as a Marker of Cardioembolic Stroke Etiology.

PMID: 34586594
Journal: Translational Stroke Research
Year: 2022
Reference: Transl Stroke Res. 2022 Dec;13(6):949-958. doi: 10.1007/s12975-021-00946-w. Epub 2021 Sep 29.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Boned, Sandra; Camacho, Jessica; Cardona, Pere; Coscojuela, Pilar; De-La-Torre, Carolina; Deck, Matias; Diaz, Humberto; Dorado, Laura; Gallur, Laura et al.
DOI: 10.1007/s12975-021-00946-w

Determinants of Leptomeningeal Collateral Status Variability in Ischemic Stroke Patients.

PMID: 34585652
Journal: CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Year: 2022
Reference: Can J Neurol Sci. 2022 Nov;49(6):767-773. doi: 10.1017/cjn.2021.226. Epub 2021 Sep 29.
Impact factor:
Publication type: Paper in international publication
Authors: Demchuk, Andrew; Fainardi, Enrico; Field, Thalia S; Goyal, Mayank; Hill, Michael D; Holodinsky, Jessalyn K; Khaw, Alexander V; Menon, Bijoy K; Najm, Mohamed; Qiu, Wu et al.
DOI: 10.1017/cjn.2021.226

Validation of a cloud-based tele-stroke system reliability in determining national institutes of health stroke scale scores for acute ischemic stroke screening in the emergency department.

PMID: 36203984
Journal: Frontiers in Neurology
Year: 2022
Reference: Front Neurol. 2022 Sep 20;13:973165. doi: 10.3389/fneur.2022.973165. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Moskovitz, Anner; Ohanyan, Sona; Reznik, Anna; Ribo, Marc; Saban, Mor; Sivan-Hoffmann, Rotem et al.
DOI: 10.3389/fneur.2022.973165

Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion.

PMID: 36239645
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2022
Reference: N Engl J Med. 2022 Oct 13;387(15):1373-1384. doi: 10.1056/NEJMoa2207576.
Impact factor:
Publication type: Paper in international publication
Authors: Bian, Shichun; Brown, Scott; Brown, Scott; Cai, Kaifeng; Cai, Lipeng; Cai, Xinyu; Cao, Jiaming; Cao, Jie; Cao, Yuezhou; Chang, Mingze et al.
DOI: 10.1056/NEJMoa2207576

Impact of Multiphase Computed Tomography Angiography for Endovascular Treatment Decision-Making on Outcomes in Patients with Acute Ischemic Stroke.

PMID: 34649382
Journal: Journal of Stroke
Year: 2021
Reference: J Stroke. 2021 Sep;23(3):377-387. doi: 10.5853/jos.2021.00619. Epub 2021 Sep 30.
Impact factor:
Publication type: Paper in international publication
Authors: Abdalrahman, Sarah; Almekhlafi, Mohammed A; Demchuk, Andrew M; Fainardi, Enrico; Goyal, Mayank; Hafeez, Moiz; Hill, Michael D; Khaw, Alexander; Menon, Bijoy K; Najm, Mohamed et al.
DOI: 10.5853/jos.2021.00619

Effectiveness of Thrombectomy in Stroke According to Baseline Prognostic Factors: Inverse Probability of Treatment Weighting Analysis of a Population-Based Registry.

PMID: 34649384
Journal: Journal of Stroke
Year: 2021
Reference: J Stroke. 2021 Sep;23(3):401-410. doi: 10.5853/jos.2021.00962. Epub 2021 Sep 30.
Impact factor:
Publication type: Paper in international publication
Authors: Almendros, Maria Cruz; Amaro, Sergio; Aragones, Josep Maria; Baiges, Juanjo; Barcelo, Miquel; Canovas, David; Cardona, Pedro; Carrion, Dolors; Catena, Esther; Chamorro, Angel et al.
DOI: 10.5853/jos.2021.00962

Impact of general anesthesia on posterior circulation large vessel occlusions after endovascular thrombectomy.

PMID: 33573525
Journal: International Journal of Stroke
Year: 2021
Reference: Int J Stroke. 2021 Oct;16(7):792-797. doi: 10.1177/1747493020976247. Epub 2020 Dec 1.
Impact factor:
Publication type: Paper in international publication
Authors: Bashir, Saima; Camps-Renom, Pol; Canovas, David; Cardona, Pere; Chamorro, Angel; de la Ossa, Natalia P; Hernandez-Perez, Maria; Molina, Carlos; Purroy, Francisco; Rodriguez-Campello, Ana et al.
DOI: 10.1177/1747493020976247

MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy.

PMID: 34530925
Journal: Acta Neuropathologica Communications
Year: 2021
Reference: Acta Neuropathol Commun. 2021 Sep 16;9(1):154. doi: 10.1186/s40478-021-01257-9.
Impact factor:
Publication type: Paper in international publication
Authors: Bonaterra-Pastra, Anna; Camacho, Jessica; Castillo-Ribelles, Laura; de Kort, Anna M; Delgado, Pilar; Hernandez-Guillamon, Mar; Klijn, Catharina J M; Kuiperij, H Bea; Marazuela, Paula; Martinez-Saez, Elena et al.
DOI: 10.1186/s40478-021-01257-9

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.

PMID: 33176180
Journal: LANCET
Year: 2020
Reference: Lancet. 2020 Nov 14;396(10262):1574-1584. doi: 10.1016/S0140-6736(20)32163-2. Epub 2020 Nov 8.
Impact factor:
Publication type: Review in international publication
Authors: Aarnio, K; Acosta, Boris Raul; Aegidius, Karen; Akutsu, Tsugio; Albiker, Christian; Alegiani, Anna; Alemseged, F; Almendrote, Miriam; Alonso, Angelika; Althaus, Katharina et al.
DOI: 10.1016/S0140-6736(20)32163-2

Management of acute stroke. Specific nursing care and treatments in the stroke unit.

PMID: 33153769
Journal: NEUROLOGIA
Year: 2020
Reference: Neurologia (Engl Ed). 2020 Nov 2:S0213-4853(20)30291-7. doi: 10.1016/j.nrl.2020.07.025.
Impact factor:
Publication type: Review in national publication
Authors: Boned, S; Calleja, L; Dalmases, G; Deck, M; Gallego, J C; Garcia-Tornel, A; Gonzalez, Y; Gutierrez, T; Juega, J M; Lorenzo, E et al.
DOI: 10.1016/j.nrl.2020.07.025

SAA (Serum Amyloid A): A Novel Predictor of Stroke-Associated Infections.

PMID: 33161846
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Dec;51(12):3523-3530. doi: 10.1161/STROKEAHA.120.030064. Epub 2020 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Azurmendi Gil, Leire; Boned, Sandra; Bustamante, Alejandro; Faura, Julia; Fluri, Felix; Katan, Mira; Lapierre-Fetaud, Vanessa; Luft, Andreas; Montaner, Joan; Sanchez, Jean-Charles et al.
DOI: 10.1161/STROKEAHA.120.030064

Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Transient Ischemic Attack in Prevention of Disabling Stroke: A Randomized Clinical Trial.

PMID: 33159526
Journal: JAMA Neurology
Year: 2020
Reference: JAMA Neurol. 2020 Nov 7;78(2):1-9. doi: 10.1001/jamaneurol.2020.4396.
Impact factor:
Publication type: Paper in international publication
Authors: Adami, Alessandro; Adrasetty, Gopal Rao; Agnelli, Giancarlo; Ahmed, Niaz; Akhmadeeva, Leila; Aksentiev, Sergei; Al-Senani, Fahmi; Alamowitch, Sonia; Alghamdi, Saeed; Alhussein, Fawaz et al.
DOI: 10.1001/jamaneurol.2020.4396

Implementation of a protocol for direct stroke patient transfer and mobilization of a stroke team to reduce times to reperfusion.

PMID: 31777209
Journal: Emergencias
Year: 2019
Reference: Emergencias. 2019 Dic;31(6):385-390.
Impact factor:
Publication type: Paper in international publication
Authors: Calleja Macho, Laura; Giron Espot, Pilar; Rodriguez-Samaniego, Maria Teresa; Rubiera Del Fueyo, Marta; Sanjuan Menendez, Estela; Santana Roman, Katherine E et al.
DOI:

The ADAN Scale: A proposed scale for prehospital use to identify status epilepticus.

PMID: 30565357
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2019
Reference: Eur J Neurol. 2019 May;26(5):760-e55. doi: 10.1111/ene.13885. Epub 2019 Jan 20.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, Laura; Fonseca, Elena; Mazuela, Gonzalo; Olive, Marta; Quintana, Manuel; Requena, Manuel; Salas-Puig, Xavier; Santamarina, Estevo; Toledo, Manuel et al.
DOI: 10.1111/ene.13885

PATJ Low Frequency Variants Are Associated with Worse Ischemic Stroke Functional Outcome: A Genome-Wide Meta-Analysis.

PMID: 30582445
Journal: CIRCULATION RESEARCH
Year: 2019
Reference: Circ Res. 2019 Jan 4;124(1):114-120. doi: 10.1161/CIRCRESAHA.118.313533.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Bustamante, Alejandro; Carrera, Caty; Castellanos, Mar; Cruchaga, Carlos; Cuadrado-Godia, Elisa; Cullell, Natalia; Davalos, Antoni; Delgado, Pilar; Diaz-Navarro, Rosa M et al.
DOI: 10.1161/CIRCRESAHA.118.313533

Intensive Care to Facilitate Organ Donation: A Report on the 4-Year Experience of a Spanish Center With a Multidisciplinary Model to Promote Referrals Out of the Intensive Care Unit.

PMID: 31627922
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2019
Reference: Transplant Proc. 2019 Nov;51(9):3018-3026. doi: 10.1016/j.transproceed.2019.08.025. Epub 2019 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Baena, Jacinto; Baguena, Marcelino; Boned, Sandra; Ferrer, Ricard; Gomez, Aroa; Mazo, Cristopher; Nuvials, Francesc Xavier; Pont, Teresa; Rubiera, Marta; Sandiumenge, Alberto et al.
DOI: 10.1016/j.transproceed.2019.08.025

Blood pressure lowering in acute intracerebral hemorrhage.

PMID: 30404950
Journal: Aging-US
Year: 2018
Reference: Aging (Albany NY). 2018 Nov 7;10(11):3056-3057. doi: 10.18632/aging.101637.
Impact factor:
Publication type: Paper in international publication
Authors: Pancorbo, Olalla; Rodriguez-Luna, David et al.
DOI: 10.18632/aging.101637

Direct Transfer to Angio-Suite to Reduce Workflow Times and Increase Favorable Clinical Outcome.

PMID: 30355182
Journal: STROKE
Year: 2018
Reference: Stroke. 2018 Nov;49(11):2723-2727. doi: 10.1161/STROKEAHA.118.021989.
Impact factor:
Publication type: Paper in international publication
Authors: Aires, Ana; Boned, Sandra; Coscojuela, Pilar; Juega, Jesus; Martins, Nuno; Mendez, Beatriz; Molina, Carlos A; Muchada, Marian; Pagola, Jorge; Requena, Manuel et al.
DOI: 10.1161/STROKEAHA.118.021989

Endovascular Thrombectomy for Mild Strokes: How Low Should We Go?

PMID: 30355094
Journal: STROKE
Year: 2018
Reference: Stroke. 2018 Oct;49(10):2398-2405. doi: 10.1161/STROKEAHA.118.022114.
Impact factor:
Publication type: Paper in international publication
Authors: Abraham, Michael; Cai, Chunyan; Chen, Michael; Costa, Renata; Elijovich, Lucas; Farrell, Christine M; Goyal, Nitin; Graybeal, Dion; Grotta, James C; Hasan, Rashedul et al.
DOI: 10.1161/STROKEAHA.118.022114

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data.

PMID: 30264728
Journal: LANCET NEUROLOGY
Year: 2018
Reference: Lancet Neurol. 2018 Oct;17(10):895-904. doi: 10.1016/S1474-4422(18)30242-4. Epub 2018 Sep 18.
Impact factor:
Publication type: Paper in international publication
Authors: Aceituno, A; Acosta, I; Adams, A; Adatia, S; Aerden, Leo A M; Aeron-Thomas, John; Aggour, Mohamed; Aghaebrahim, A; Agid, R; Aguettaz, Pierre et al.
DOI: 10.1016/S1474-4422(18)30242-4

Admission CT perfusion may overestimate initial infarct core: the ghost infarct core concept.

PMID: 27566491
Journal: Journal of NeuroInterventional Surgery
Year: 2017
Reference: J Neurointerv Surg. 2017 Jan;9(1):66-69. doi: 10.1136/neurintsurg-2016-012494. Epub 2016 Aug 26.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Boned, Sandra; Coscojuela, Pilar; Flores, Alan; Juega, Jesus; Molina, Carlos A; Muchada, Marian; Padroni, Marina; Pagola, Jorge; Ribo, Marc et al.
DOI: 10.1136/neurintsurg-2016-012494

The impact of post-stroke complications on in-hospital mortality depends on stroke severity.

PMID: 31008302
Journal: European stroke journal
Year: 2017
Reference: Eur Stroke J. 2017 Mar;2(1):54-63. doi: 10.1177/2396987316681872. Epub 2016 Nov 28.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Bustamante, Alejandro; Garcia-Berrocoso, Teresa; Giralt, Dolors; Molina, Carlos; Montaner, Joan; Rubiera, Marta; Serena, Joaquin et al.
DOI: 10.1177/2396987316681872

Off-Label Use of Direct Oral Anticoagulants in Intracerebral Hemorrhage Patients With Prosthetic Valves.

PMID: 29030474
Journal: STROKE
Year: 2017
Reference: Stroke. 2017 Nov;48(11):3183-3186. doi: 10.1161/STROKEAHA.117.017592. Epub 2017 Oct 13.
Impact factor:
Publication type: Paper in international publication
Authors: Chaturvedi, Seemant; Diener, Hans-Christoph; Hohnloser, Stefan H; Molina, Carlos A; Selim, Magdy H et al.
DOI: 10.1161/STROKEAHA.117.017592

Thrombectomy in Acute Stroke With Tandem Occlusions From Dissection Versus Atherosclerotic Cause.

PMID: 28974628
Journal: STROKE
Year: 2017
Reference: Stroke. 2017 Nov;48(11):3145-3148. doi: 10.1161/STROKEAHA.117.018264. Epub 2017 Oct 3.
Impact factor:
Publication type: Paper in international publication
Authors: Behme, Daniel; Boutchakova, Maria; Cognard, Christophe; Dorn, Franziska; Eiden, Sebastian; Gory, Benjamin; Haussen, Diogo C; Holtmannspotter, Markus; Killer-Oberpfalzer, Monika; Labreuche, Julien et al.
DOI: 10.1161/STROKEAHA.117.018264

CBV_ASPECTS Improvement over CT_ASPECTS on Determining Irreversible Ischemic Lesion Decreases over Time.

PMID: 27781042
Journal: Interventional neurology
Year: 2016
Reference: Interv Neurol. 2016 Sep;5(3-4):140-147. Epub 2016 Jun 28.
Impact factor:
Publication type: Paper in international publication
Authors: Boned, Sandra; Cabero, Jordi; Coscojuela, Pilar; Juega, Jesus M; Molina, Carlos A; Muchada, Marian; Padroni, Marina; Pagola, Jorge; Ribo, Marc; Rodriguez-Luna, David et al.
DOI: 10.1159/000446969

Improving the Evaluation of Collateral Circulation by Multiphase Computed Tomography Angiography in Acute Stroke Patients Treated with Endovascular Reperfusion Therapies.

PMID: 27781051
Journal: Interventional neurology
Year: 2016
Reference: Interv Neurol. 2016 Sep;5(3-4):209-217. Epub 2016 Sep 1.
Impact factor:
Publication type: Paper in international publication
Authors: Boned, Sandra; Carvalho, Vanessa; Coscojuela, Pilar; Flores, Alan; Garcia-Tornel, Alvaro; Goyal, Mayank; Juega, Jesus; Menon, Bijoy; Molina, Carlos A; Muchada, Marian et al.
DOI: 10.1159/000448525

Combination of Thrombolysis and Statins in Acute Stroke Is Safe: Results of the STARS Randomized Trial (Stroke Treatment With Acute Reperfusion and Simvastatin).

PMID: 27758944
Journal: STROKE
Year: 2016
Reference: Stroke. 2016 Nov;47(11):2870-2873. doi: 10.1161/STROKEAHA.116.014600. Epub 2016 Oct 6.
Impact factor:
Publication type: Clinical Trials
Authors: Bravo, Yolanda; Bustamante, Alejandro; Canovas, David; Corbeto, Natalia; de Arce, Anna; de la Torre, Javier; Delgado, Pilar; Delgado-Mederos, Raquel; Freijo, Mar; Garcia-Matas, Silvia et al.
DOI: 10.1161/STROKEAHA.116.014600

Prehospital Scales to Identify Patients With Large Vessel Occlusion: It Is Time for Action.

PMID: 27758947
Journal: STROKE
Year: 2016
Reference: Stroke. 2016 Nov;47(11):2877-2878. doi: 10.1161/STROKEAHA.116.014911. Epub 2016 Oct 6.
Impact factor:
Publication type: Paper in international publication
Authors: Abilleira, Sonia; Jimenez, Xavier; Perez de la Ossa, Natalia; Ribo, Marc et al.
DOI: 10.1161/STROKEAHA.116.014911

Endovascular treatment for M2 occlusions in the era of stentrievers: a descriptive multicenter experience.

PMID: 24578483
Journal: J NEUROINTERV SURG
Year: 2015
Reference: J Neurointerv Surg. 2015 Apr;7(4):234-7. doi: 10.1136/neurintsurg-2014-011100. Epub 2014 Feb 27.
Impact factor:
Publication type: Paper in international publication
Authors: Abilleira, Sonia; Canovas, David; Cardona, Pere; de Miquel, M Angeles; Flores, Alan; Garcia Bermejo, Pablo; Gomis, Meritxell; Marti-Fabregas, Joan; Obach, Victor; Ribo, Marc et al.
DOI: 10.1136/neurintsurg-2014-011100

Intracerebral Hematoma Morphologic Appearance on Noncontrast Computed Tomography Predicts Significant Hematoma Expansion.

PMID: 26451019
Journal: STROKE
Year: 2015
Reference: Stroke. 2015 Nov;46(11):3111-6. doi: 10.1161/STROKEAHA.115.010566. Epub 2015 Oct 8.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Hazzaa, Mohammed; Aviv, Richard I; Bhatia, Rohit; Blacquiere, Dylan; Boulanger, Jean-Martin; Czlonkowska, Anna; Demchuk, Andrew M; Deshpande, Anirudda; Dowlatshahi, Dar; Dzialowski, Imanuel et al.
DOI: 10.1161/STROKEAHA.115.010566

Maximal Admission Core Lesion Compatible With Favorable Outcome in Acute Stroke Patients Undergoing Endovascular Procedures.

PMID: 26294674
Journal: STROKE
Year: 2015
Reference: Stroke. 2015 Oct;46(10):2849-52. doi: 10.1161/STROKEAHA.115.010707. Epub 2015 Aug 20.
Impact factor:
Publication type: Paper in international publication
Authors: Bonet, Sandra; Coscojuela, Pilar; Flores, Alan; Lemus, Miguel; Molina, Carlos A; Muchada, Marian; Pagola, Jorge; Ribo, Marc; Rodriguez-Luna, David; Rovira, Alex et al.
DOI: 10.1161/STROKEAHA.115.010707

Poor Collateral Circulation Assessed by Multiphase Computed Tomographic Angiography Predicts Malignant Middle Cerebral Artery Evolution After Reperfusion Therapies.

PMID: 26419969
Journal: STROKE
Year: 2015
Reference: Stroke. 2015 Nov;46(11):3149-53. doi: 10.1161/STROKEAHA.115.010608. Epub 2015 Sep 29.
Impact factor:
Publication type: Paper in international publication
Authors: Boned, Sandra; Carcamo, Daniel; Coscojuela, Pilar; Flores, Alan; Lemus, Miguel; Meler, Pilar; Molina, Carlos A; Muchada, Marian; Pagola, Jorge; Ribo, Marc et al.
DOI: 10.1161/STROKEAHA.115.010608

Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial.

PMID: 24895878
Journal: RADIOLOGY
Year: 2014
Reference: Radiology. 2014 Oct;273(1):202-10. doi: 10.1148/radiol.14132649. Epub 2014 Jun 5.
Impact factor:
Publication type: Clinical Trials
Authors: Abbott, L; Abou-Chebl, A; Albuquerque, F; Amarenco, P; Amarenco, P; Anderson, C; Arora, A; Atkinson, R; Barnwell, S; Baxter, B et al.
DOI: 10.1148/radiol.14132649

Functional Outcome After Primary Endovascular Therapy or IV Thrombolysis Alone for Stroke. An Observational, Comparative Effectiveness Study.

PMID: 25428822
Journal: CEREBROVASCULAR DISEASES
Year: 2014
Reference: Cerebrovasc Dis. 2014;38(5):328-36. doi: 10.1159/000368433. Epub 2014 Nov 21.
Impact factor:
Publication type: Paper in international publication
Authors: Abilleira, Sonia; Aja, Lucia; Baiges, Joan Josep; Blasco, Jordi; Canovas, David; Cardona, Pere; Castano, Carlos; Castellanos, Mar; Chamorro, Angel; Cocho, Dolores et al.
DOI: 10.1159/000368433

Prognostic value of plasma chitotriosidase activity in acute stroke patients.

PMID: 24148838
Journal: International Journal of Stroke
Year: 2014
Reference: Int J Stroke. 2014 Oct;9(7):910-6. doi: 10.1111/ijs.12160. Epub 2013 Oct 22.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Bustamante, Alejandro; Dominguez, Carmen; Flores, Alan; Garcia-Berrocoso, Teresa; Giralt, Dolors; Llombart, Victor; Molina, Carlos; Montaner, Joan; Penalba, Ana et al.
DOI: 10.1111/ijs.12160

EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke.

PMID: 24828363
Journal: International Journal of Stroke
Year: 2014
Reference: Int J Stroke. 2014 Jul;9(5):642-5. doi: 10.1111/ijs.12294. Epub 2014 May 15.
Impact factor:
Publication type: Clinical Trials
Authors: Bath, P M W; Bath, Philip M W; Brainin, M; Broessner, G; Colam, B; Cordonnier, C; Czlonkowska, A; Dalkara, T; Demotes, J; Demotes, Jacques et al.
DOI: 10.1111/ijs.12294

Difficult catheter access to the occluded vessel during endovascular treatment of acute ischemic stroke is associated with worse clinical outcome.

PMID: 23117130
Journal: Journal of NeuroInterventional Surgery
Year: 2013
Reference: J Neurointerv Surg. 2013 May;5 Suppl 1:i70-3. doi: 10.1136/neurintsurg-2012-010438. Epub 2012 Oct 31.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Flores, Alan; Meler, Pilar; Mendonca, Nuno; Molina, Carlos A; Pagola, Jorge; Pineiro, Soco; Ribo, Marc; Rodriguez-Luna, David; Rubiera, Marta et al.
DOI: 10.1136/neurintsurg-2012-010438

Impact of blood pressure changes and course on hematoma growth in acute intracerebral hemorrhage.

PMID: 23647568
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2013
Reference: Eur J Neurol. 2013 Sep;20(9):1277-83. doi: 10.1111/ene.12180. Epub 2013 May 5.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, J; Coscojuela, P; Flores, A; Hernandez-Guillamon, M; Ibarra, B; Meler, P; Molina, C A; Montaner, J; Muchada, M; Pagola, J et al.
DOI: 10.1111/ene.12180

Arterial Blood Gas Analysis of Samples Directly Obtained Beyond Cerebral Arterial Occlusion During Endovascular Procedures Predicts Clinical Outcome.

PMID: 22211838
Journal: JOURNAL OF NEUROIMAGING
Year: 2013
Reference: J Neuroimaging. 2013 Apr;23(2):180-4. doi: 10.1111/j.1552-6569.2011.00667.x. Epub 2011 Dec 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1552-6569.2011.00667.x

[Strokes and their relationship with sleep and sleep disorders.]

PMID: 21163212
Journal: NEUROLOGIA
Year: 2013
Reference: Neurologia. 2013 Mar;28(2):103-18. doi: 10.1016/j.nrl.2010.09.016. Epub 2010 Nov 19.
Impact factor:
Publication type: Review in national publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.nrl.2010.09.016

Poststroke treatment with selective serotonin reuptake inhibitors: a journey from sadness to motor recovery.

PMID: 23065004
Journal: STROKE
Year: 2012
Reference: Stroke. 2012 Nov;43(11):3154-5. doi: 10.1161/STROKEAHA.112.657635. Epub 2012 Oct 11.
Impact factor:
Publication type: Editorail in international publication
Authors: Molina, Carlos A; Selim, Magdy H et al.
DOI: 10.1161/STROKEAHA.112.657635

Brain natriuretic Peptide is associated with worsening and mortality in acute stroke patients but adds no prognostic value to clinical predictors of outcome.

PMID: 23018289
Journal: CEREBROVASCULAR DISEASES
Year: 2012
Reference: Cerebrovasc Dis. 2012;34(3):240-5. doi: 10.1159/000341858. Epub 2012 Sep 26.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, J; Delgado, P; Garcia-Berrocoso, T; Mendioroz, M; Molina, C A; Montaner, J; Palacios, M; Perea-Gainza, M; Ribo, M; Rosell, A et al.
DOI: 10.1159/000341858

Preferential Effect of Premorbid Statins on Atherothrombotic Strokes through Collateral Circulation Enhancement.

PMID: 22906913
Journal: EUROPEAN NEUROLOGY
Year: 2012
Reference: Eur Neurol. 2012;68(3):171-6. doi: 10.1159/000337862. Epub 2012 Aug 14.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Flores, Alan; Molina, Carlos A; Pagola, Jorge; Pineiro, Socorro; Ribo, Marc; Rodriguez-Luna, David; Rubiera, Marta; Sargento-Freitas, Joao; Silva, Fernando et al.
DOI: 10.1159/000337862

IL1B and VWF Variants Are Associated With Fibrinolytic Early Recanalization in Patients With Ischemic Stroke.

PMID: 22858724
Journal: STROKE
Year: 2012
Reference: Stroke. 2012 Oct;43(10):2659-65. Epub 2012 Aug 2.
Impact factor:
Publication type: Paper in international publication
Authors: Del Rio-Espinola, Alberto; Delgado, Pilar; Domingues-Montanari, Sophie; Fernandez-Cadenas, Israel; Freijo, Mari Mar; Giralt, Dolors; Marti-Fabregas, Joan; Mendioroz, Maite; Montaner, Joan; Obach, Victor et al.
DOI: 10.1161/STROKEAHA.112.657007

First clinical use of a novel neurovascular access and neuroprotection system demonstrates complete absence of emboli by transcranial Doppler during carotid artery stenting.

PMID: 22051994
Journal: JOURNAL OF CARDIOVASCULAR SURGERY
Year: 2011
Reference: J Cardiovasc Surg (Torino). 2011 Dec;52(6):853-7.
Impact factor:
Publication type: Paper in international publication
Authors: Chou, T M; Kolvenbach, R R; Pinter, L; Ribo, M; Roberts, T et al.
DOI:

Ultraearly hematoma growth predicts poor outcome after acute intracerebral hemorrhage.

PMID: 21998314
Journal: NEUROLOGY
Year: 2011
Reference: Neurology. 2011 Oct 25;77(17):1599-604. Epub 2011 Oct 12.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1212/WNL.0b013e3182343387

European Research Priorities for Intracerebral Haemorrhage.

PMID: 21986448
Journal: CEREBROVASCULAR DISEASES
Year: 2011
Reference: Cerebrovasc Dis. 2011;32(5):409-19. Epub 2011 Oct 8.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1159/000330653

Extending the Time Window for Endovascular Procedures According to Collateral Pial Circulation.

PMID: 21960574
Journal: STROKE
Year: 2011
Reference: Stroke. 2011 Dec;42(12):3465-9. Epub 2011 Sep 29.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1161/STROKEAHA.111.623827

Mobilization, endothelial differentiation and functional capacity of endothelial progenitor cells after ischemic stroke.

PMID: 20594997
Journal: MICROVASCULAR RESEARCH
Year: 2010
Reference: Microvasc Res. 2010 Dec;80(3):317-23. Epub 2010 Jun 4.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.mvr.2010.05.008

General or Local Anesthesia During Endovascular Procedures. Sailing Quiet in the Darkness or Fast Under a Daylight Storm.

PMID: 20930154
Journal: STROKE
Year: 2010
Reference: Stroke. 2010 Nov;41(11):2720-1. Epub 2010 Oct 7.
Impact factor:
Publication type: Editorail in international publication
Authors: ; et al.
DOI: 10.1161/STROKEAHA.110.595447

The Proteome of Human Brain After Ischemic Stroke.

PMID: 20940630
Journal: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Year: 2010
Reference: J Neuropathol Exp Neurol. 2010 Nov;69(11):1105-15.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1097/NEN.0b013e3181f8c539

Bringing Forward Reperfusion with Oxygenated Blood Perfusion beyond Arterial Occlusion during Endovascular Procedures in Patients with Acute Ischemic Stroke.

PMID: 20801767
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2010
Reference: AJNR Am J Neuroradiol. 2010 Nov;31(10):1899-902. Epub 2010 Aug 26.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.3174/ajnr.A2221

Residual flow at the site of intracranial occlusion on transcranial Doppler predicts response to intravenous thrombolysis: a multi-center study.

PMID: 19018132
Journal: CEREBROVASCULAR DISEASES
Year: 2009
Reference: Cerebrovasc Dis. 2009;27(1):5-12.
Impact factor:
Publication type: Paper in international publication
Authors: Alexandrov, Andrei V; Demchuk, Andrew M; Molina, Carlos A; Saqqur, Maher; Shuaib, Ashfaq; Tsivgoulis, Georgios et al.
DOI: 10.1159/000172628

Safety and dose-escalation study design of Transcranial Ultrasound in Clinical SONolysis for acute ischemic stroke: the TUCSON Trial.

PMID: 19236498
Journal: International Journal of Stroke
Year: 2009
Reference: Int J Stroke. 2009 Feb;4(1):42-8.
Impact factor:
Publication type: Paper in international publication
Authors: Alexandrov, Andrei V; Amarenco, Pierre; Barreto, Andrew D; Lao, Annabelle Y; Molina, Carlos A; Schellinger, Peter D; Sharma, Vijay K; Sierzenski, Paul et al.
DOI: 10.1111/j.1747-4949.2009.00252.x

Transcranial duplex sonography for monitoring hyperacute intracerebral hemorrhage.

PMID: 19164795
Journal: STROKE
Year: 2009
Reference: Stroke. 2009 Mar;40(3):987-90.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Delgado, Pilar; Delgado-Mederos, Raquel; Maisterra, Olga; Molina, Carlos A; Ortega, Gema; Perez, Estevo Santamarina; Ribo, Marc; Rubiera, Marta et al.
DOI: 10.1161/STROKEAHA.108.524249

Recanalization and reperfusion therapies for acute ischemic stroke.

PMID: 19342847
Journal: CEREBROVASCULAR DISEASES
Year: 2009
Reference: Cerebrovasc Dis. 2009;27 Suppl 1:162-7.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Molina, Carlos A et al.
DOI: 10.1159/000200455

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News

This project seeks to promote the use of artificial intelligence in stroke treatment, improving data management, transparency and clinical monitoring of patients.

A new consortium of leading organizations embarks on a groundbreaking project to enhance patient triage and healthcare delivery.

UMBRELLA, a consortium of over 20 public and private partners, kicks off this week with the aim of revolutionising the entire stroke care pathway in Europe by adopting a holistic approach that covers stroke diagnosis, prevention and care.