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Stroke Research

The search for quality and innovation has always been an inherent part of the activity of the Stroke Research Group and represents the common thread that leads us to excellence and continuous improvement.

In recent years, the Stroke Research Group has established itself as a leader in the management, recruitment and international coordination of multicenter clinical trials, as well as in the development of patents for new thrombectomy devices and the creation of new technological solutions and digital platforms to improve the diagnosis, treatment and follow-up of stroke patients. Robust strategic alliances have also been consolidated with public and private entities that ensure the viability and scalability of the research projects initiated in our group.

The Stroke Research Group is made up of a transversal and multidisciplinary team that shares a common idea: to contribute from its area of knowledge to the care and management of stroke through the effective transfer of knowledge and the complementarity of the processes of clinical research.

Publications

Torque Teno Virus plasma DNA load: a novel prognostic biomarker in CAR-T therapy.

PMID: 37919456
Journal: BONE MARROW TRANSPLANTATION
Year: 2023
Reference: Bone Marrow Transplant. 2023 Nov 2. doi: 10.1038/s41409-023-02114-0.
Impact factor:
Publication type: Paper in international publication
Authors: Albert, Eliseo; Amat, Paula; Balaguer, Aitana; Barba, Pere; Beas, Francisco; Benzaquen, Ana; Bhuva, Parita; Bonafe, Alain; Budzik, Ronald F; Campos, Diana et al.
DOI: 10.1038/s41409-023-02114-0

Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT.

PMID: 37919201
Journal: Enfermedades infecciosas y microbiologia clinica (
Year: 2023
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2023 Oct 31:S2529-993X(23)00255-1. doi: 10.1016/j.eimce.2023.07.007.
Impact factor:
Publication type: Clinical guide
Authors: Albucher, Jean Francois; Ariza, Javier; Baeza, Jose; Belzunegui-Otano, Joaquin; Benito, Natividad; Buetikofer, Lukas; Cobo, Javier; Del-Toro, Maria-Dolores; Dobrocky, Tomas; Eker, Omer et al.
DOI: 10.1016/j.eimce.2023.07.007

VacLok-Augmented Direct Aspiration Thrombectomy : A Novel Method of an Aspiration First-pass Approach for Acute Ischemic Stroke.

PMID: 37932449
Journal: Clinical Neuroradiology
Year: 2023
Reference: Clin Neuroradiol. 2023 Nov 6. doi: 10.1007/s00062-023-01354-3.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Almenar-Bonet, Luis; Andersson, Tommy; Atienza, Felipe; Aurelio Sarralde-Aguayo, Jose; Baguda, Javier De Juan; Barge-Caballero, Eduardo; Blasco-Peiro, Teresa; Camino, Manuela; Carlos Sanchez-Salado, Jose; Coll, Elisabeth et al.
DOI: 10.1007/s00062-023-01354-3

JAK-inhibitor treatment for inborn errors of JAK/STAT signaling: An ESID and EBMT IEWP retrospective study.

PMID: 37935260
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2023
Reference: J Allergy Clin Immunol. 2023 Nov 5:S0091-6749(23)01390-8. doi: 10.1016/j.jaci.2023.10.018.
Impact factor:
Publication type: Paper in international publication
Authors: Albert, Michael H; Andersson, Tommy; Aumann, Volker; Bakhtiar, Shahrzad; Barlogis, Vincent; Booth, Claire; Buddingh, Emmeline P; Cagdas, Deniz; Castelle, Martin; Chan, Alice Y et al.
DOI: 10.1016/j.jaci.2023.10.018

Herpes simplex encephalitis in the context of immune checkpoint inhibitors: a complex interplay.

PMID: 34988947
Journal: ACTA NEUROLOGICA BELGICA
Year: 2022
Reference: Acta Neurol Belg. 2022 Jun;122(3):823-825. doi: 10.1007/s13760-021-01864-2. Epub 2022 Jan 6.
Impact factor: 2.396
Publication type: Letter or abstract
Authors: Lallana, Sofia; Sanchez-Tejerina, Daniel; Auger, Cristina; Callejo, Ana; Rio, Jordi; Cobo-Calvo, Alvaro et al.
DOI: 10.1007/s13760-021-01864-2

Disentangling Workflow Paradigms and Treatment Decision-Making in Acute Ischemic Stroke-Reply.

PMID: 35129613
Journal: JAMA Neurology
Year: 2022
Reference: JAMA Neurol. 2022 Mar 1;79(3):312. doi: 10.1001/jamaneurol.2021.5346.
Impact factor: 18.302
Publication type: Letter or abstract
Authors: Ribo, Marc; Requena, Manuel et al.
DOI: 10.1001/jamaneurol.2021.5346

Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial.

PMID: 35143603
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2022
Reference: JAMA. 2022 Mar 1;327(9):826-835. doi: 10.1001/jama.2022.1645.
Impact factor: 56.274
Publication type: Paper in international publication
Authors: Avellaneda, C; Camps-Renom, Pol; Zarco, Federico; Oleaga, Laura; Cardona, Pere; Castano, Carlos; Macho, Juan; Cuadrado-Godia, Elisa; Vivas, Elio; Lopez-Rueda, Antonio et al.
DOI: 10.1001/jama.2022.1645

REACT Aspiration Catheters: Clinical Experience and Technical Considerations.

PMID: 35718472
Journal: Neurointervention
Year: 2022
Reference: Neurointervention. 2022 Jul;17(2):70-77. doi: 10.5469/neuroint.2022.00255. Epub 2022 Jun 20.
Impact factor: 0
Publication type: Review in international publication
Authors: Li, Jiahui; Ribo, Marc et al.
DOI: 10.5469/neuroint.2022.00255

Systematic CT perfusion acquisition in acute stroke increases vascular occlusion detection and thrombectomy rates.

PMID: 34857668
Journal: Journal of NeuroInterventional Surgery
Year: 2021
Reference: J Neurointerv Surg. 2021 Dec 2. pii: neurintsurg-2021-018241. doi: 10.1136/neurintsurg-2021-018241.
Impact factor: 5.836
Publication type: Paper in international publication
Authors: Olive-Gadea, Marta, Requena, Manuel, Diaz, Facundo, Boned, Sandra, Garcia-Tornel, Alvaro, Muchada, Marian, Deck, Matias, Lozano, Prudencio, Rodriguez-Villatoro, Noelia, Juega, Jesus et al.
DOI: 10.1136/neurintsurg-2021-018241

Direct Transfer to Angiosuite in Acute Stroke: Why, When, and How?

PMID: 34785602
Journal: NEUROLOGY
Year: 2021
Reference: Neurology. 2021 Nov 16;97(20 Supplement 2):S34-S41. doi: 10.1212/WNL.0000000000012799.
Impact factor: 9.91
Publication type: Review in international publication
Authors: Requena, Manuel, Ren, Zeguang, Ribo, Marc et al.
DOI: 10.1212/WNL.0000000000012799

Monocyte-to-Lymphocyte Ratio in Clot Analysis as a Marker of Cardioembolic Stroke Etiology.

PMID: 34586594
Journal: Translational Stroke Research
Year: 2021
Reference: Transl Stroke Res. 2021 Sep 29. pii: 10.1007/s12975-021-00946-w. doi: 10.1007/s12975-021-00946-w.
Impact factor: 6.829
Publication type: Paper in international publication
Authors: Ribo, Marc, Juega, Jesus, Palacio-Garcia, Carlos, Rodriguez, Maite, Deck, Matias, Rodriguez-Luna, David, Requena, Manuel, Garcia-Tornel, Alvaro, Rodriguez-Villatoro, Noelia, Rubiera, Marta et al.
DOI: 10.1007/s12975-021-00946-w

Impact of COVID-19 Infection on the Outcome of Patients With Ischemic Stroke.

PMID: 34455823
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 Dec;52(12):3908-3917. doi: 10.1161/STROKEAHA.121.034883. Epub 2021 Aug 30.
Impact factor: 7.914
Publication type: Paper in international publication
Authors: Martinez-Domeno, Alejandro, Prats-Sanchez, Luis, Guasch-Jimenez, Marina, Cardona, Pere, Nunez-Guillen, Ana, Requena, Manuel, Rubiera, Marta, Olive, Marta, Bustamante, Alejandro, Gomis, Meritxell et al.
DOI: 10.1161/STROKEAHA.121.034883

Circulating Aquaporin-4 as a biomarker of early neurological improvement in stroke patients: a pilot study.

PMID: 31672489
Journal: NEUROSCIENCE LETTERS
Year: 2020
Reference: Neurosci Lett. 2020 Jan 1;714:134580. doi: 10.1016/j.neulet.2019.134580. Epub 2019 Oct 28.
Impact factor:
Publication type: Paper in international publication
Authors: Bustamante, Alejandro; Garcia-Tornel, Alvaro; Mancha, Fernando; Montaner, Joan; Penalba, Anna; Ramiro, Laura; Rovira, Alex; Simats, Alba et al.
DOI: 10.1016/j.neulet.2019.134580

Angioplasty with a retrievable stent to treat vasospasm secondary to subarachnoid hemorrhage due to an aneurysm: a multicenter study of safety and efficacy.

PMID: 32622517
Journal: Radiologia
Year: 2020
Reference: Radiologia (Engl Ed). 2020 Jul 1:S0033-8338(20)30072-2. doi: 10.1016/j.rx.2020.04.011.
Impact factor:
Publication type: Paper in national publication
Authors: Aja, L; Chirife, O; Lopez-Rueda, A; Pinana, C; Remollo, S; Tomasello, A; Vargas, A; Werner, M et al.
DOI: 10.1016/j.rx.2020.04.011

Spontaneous systolic blood pressure drop early after mechanical thrombectomy predicts dramatic neurological recovery in ischaemic stroke patients.

PMID: 33598554
Journal: European stroke journal
Year: 2020
Reference: Eur Stroke J. 2020 Dec;5(4):362-369. doi: 10.1177/2396987320933384. Epub 2020 Jun 11.
Impact factor: 0
Publication type: Paper in international publication
Authors: Ribo, Marc, Tomasello, Alejandro, Molina, Carlos A, Rubiera, Marta, Deck, Matias, Juega, Jesus, Pagola, Jorge, Rodriguez-Villatoro, Noelia, Carvalho Dias, Mariana, Gabriel, Denis et al.
DOI: 10.1177/2396987320933384

Management of acute stroke. Specific nursing care and treatments in the stroke unit.

PMID: 33153769
Journal: NEUROLOGIA
Year: 2020
Reference: Neurologia. 2020 Nov 2. pii: S0213-4853(20)30291-7. doi: 10.1016/j.nrl.2020.07.025.
Impact factor: 2.283
Publication type: Review in national publication
Authors: Rodriguez-Luna, D, Sanjuan, E, Pancorbo, O, Santana, K, Minarro, O, Sala, V, Muchada, M, Boned, S, Juega, J M, Pagola, J et al.
DOI: 10.1016/j.nrl.2020.07.025

Mechanical thrombectomy for basilar artery occlusion: efficacy, outcomes, and futile recanalization in comparison with the anterior circulation.

PMID: 31239331
Journal: Journal of NeuroInterventional Surgery
Year: 2019
Reference: J Neurointerv Surg. 2019 Dec;11(12):1174-1180. doi: 10.1136/neurintsurg-2018-014516. Epub 2019 Jun 25.
Impact factor: 3.925
Publication type: Paper in international publication
Authors: Michel, Patrik, Hajdu, Steven, Ribo, Marc, Requena, Manuel, Maegerlein, Christian, Friedrich, Benjamin, Costalat, V, Benali, Amel, Pierot, Laurent, Gawlitza, Matthias et al.
DOI: 10.1136/neurintsurg-2018-014516

When to Stop.

PMID: 31177974
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Jul;50(7):1781-1788. doi: 10.1161/STROKEAHA.119.025088. Epub 2019 Jun 10.
Impact factor: 6.046
Publication type: Paper in international publication
Authors: Olive-Gadea, Marta, Garcia-Tornel, Alvaro, Requena, Manuel, Rubiera, Marta, Muchada, Marian, Pagola, Jorge, Rodriguez-Luna, David, Deck, Matias, Juega, Jesus, Rodriguez-Villatoro, Noelia et al.
DOI: 10.1161/STROKEAHA.119.025088

Farmalarm: Application for Mobile Devices Improves Risk Factor Control After Stroke

PMID: 31167621
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Jul;50(7):1819-1824. doi: 10.1161/STROKEAHA.118.024355. Epub 2019 Jun 6.
Impact factor: 6.046
Publication type: Paper in international publication
Authors: Juega, Jesus, Garcia-Tornel, Alvaro, Rodriguez-Luna, David, Pagola, Jorge, Rubiera, Marta, Molina, Carlos A, Ribo, Marc, Rodriguez-Villatoro, Noelia, Lopez, Rosa, Boned, Sandra et al.
DOI: 10.1161/STROKEAHA.118.024355

Predictors of response to endovascular treatment of posterior circulation stroke.

PMID: 31153569
Journal: EUROPEAN JOURNAL OF RADIOLOGY
Year: 2019
Reference: Eur J Radiol. 2019 Jul;116:219-224. doi: 10.1016/j.ejrad.2019.05.001. Epub 2019 May 2.
Impact factor: 2.948
Publication type: Paper in international publication
Authors: Tomasello, Alejandro, Molina, Carlos, Rovira, Alex, Rubiera, Marta, Gramegna, Laura Ludovica, Requena, Manuel, Dinia, Lavinia, Melendez, Fernando, Hernandez, David, Coscojuela, Pilar et al.
DOI: 10.1016/j.ejrad.2019.05.001

Blog

News

This project seeks to promote the use of artificial intelligence in stroke treatment, improving data management, transparency and clinical monitoring of patients.

A new consortium of leading organizations embarks on a groundbreaking project to enhance patient triage and healthcare delivery.

UMBRELLA, a consortium of over 20 public and private partners, kicks off this week with the aim of revolutionising the entire stroke care pathway in Europe by adopting a holistic approach that covers stroke diagnosis, prevention and care.