Dr. Josep Gámez, head of the Peripheral Nervous System group at Vall d’Hebron Institute of Research (VHIR), presented the book "http://www.plataformaafectadosela.org/2013/09/muneca-de-trapo-de-leo-montero/" "Muñeca de trapo", written by Leo Montero, a 45 year-old patient with Amyotrophic Lateral Sclerosis (ALS). Leo explains in her book the daily life of this progressive neurodegenerative disease, from the emotions, love, acceptance and depression, to the thought of dying. Dr. Gámez describes her as "a fighter who doesn’t conform to the lack of treatment" and highlights the activities that she has carried out in order to get funds to receive stem cell transplants. Dr. Gámez met her in 2009 when she came from Dènia to receive a third medical opinion and the confirmation of the fearing diagnosis. Now, 6 years after the first diagnosis, Leo defines herself as a "rug doll" who has seen the death of all her body, except her brain. The cause of ALS is unknown, there is no cure and no treatment available. It is a debilitating disease characterized by the loss of motor neurons which cause rapidly progressive weakness, muscle atrophy and the death of the patient by breathing failure. Dr. Josep Gámez leads at VHIR "http://www.vhir.org/larecerca/grupsrecerca/ca_grups_linees.asp?Idioma=en&mv1=2&mv2=1&mh1=2&mh2=1&mh3=1&mh4=0&ms=0&area=4&grup=12&menu=2" three research lines in the molecular mechanisms and genetic mutations in ALS, and participates in "http://www.alsuntangled.com/" ALSUntangled, which is a network of clinical experts with the aim of offering alternative or off-label ALS treatments.