Estudio de fase 3 de pembrolizumab en combinación con carboplatino/taxano (paclitaxel o nab-paclitaxel) seguido de pembrolizumab con o sin mantenimiento con MK 2870 en el tratamiento de primera línea del cáncer pulmonar no microcítico epidermoide metastásico

• Protocol code: MK-2870-023
• EudraCT code: No aplica
• Service: Ophthalmology
• Principal investigator:  Pardo Aranda, Alejandro
• Pathology: Malalties de l’ull i dels seus annexos
• Phase: Fase III

An open-label extension trial of the long-term safety and efficacy ofBl 1015550 taken orally in patients with idiopathic pulmonary fibrosis (IPF) andprogressive pulmonary fibrosis (PPF)

• Protocol code: 1305-0031
• EudraCT code: No aplica
• Research group: Pneumology
• Service: Pneumology
• Principal investigator:  Ojanguren Arranz, Iñigo
• Pathology: Malalties del sistema respiratori
• Phase: Fase III
• Status: Recruiting volunteers

A randomised, double-blind, parallel group, roll-over study evaluatinglong-term safety and efficacy of oral doses of BI 1291583 q.d. in patients withbronchiectasis (ClairleafTM)/ Estudio de continuación, aleatorizado, doble ciego y congrupos paralelos para evaluar la eficacia y la seguridad a largo plazo de dosis orales deBI 1291583 una vez al día en pacientes con bronquiectasia (ClairleafTM)

• Protocol code: 1397-0017
• EudraCT code: No aplica
• Research group: Shock, Organ Dysfunction and Resuscitation
• Service: RTA ICU
• Principal investigator:  Alvarez Gonzalez, Antonio
• Phase: Fase II

Estudio de fase 2/3, multicéntrico, aleatorizado, doble ciego ycontrolado con placebo para evaluar la eficacia, la seguridad y la tolerabilidad de BHV-7000 en sujetos con epilepsia de inicio focal refractaria

• Protocol code: BHV7000-303
• EudraCT code: No aplica
• Research group: Research Group on Status Epilepticus and Acute Seizures
• Service: Neurology
• Principal investigator:  Toledo Argany, Manuel
• Pathology: Tumors
• Phase: Fase III

Estudio de fase 3, aleatorizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia y la seguridad de belimumab administrado por vía subcutánea en adultos con enfermedad pulmonar intersticial (EPI) asociada a enfermedad del tejido conectivo (ETC).

• Protocol code: 221672
• EudraCT code: No aplica
• Research group: Systemic Diseases
• Service: Internal Medicine
• Principal investigator:  Mestre Torres, Jaume
• Phase: Fase III

A phase II, randomized, open-label study to assess the efficacy, safety, and pharmacokinetics (PK) of maintenance cabozantinib (XL184) plus best supportive care (BSC) versus BSC in children, adolescents and young adults (AYA) with unresectable residual osteosarcoma either at diagnosis or at first relapse after standard treatment.

• Protocol code: CLIN-60000-461
• EudraCT code: No aplica
• Research group: Childhood Cancer and Blood Disorders
• Service: Pediatric Oncohematology
• Principal investigator:  Gros Subias, Luís
• Pathology: Tumors
• Phase: Fase II

A Randomized, Double-blind, Placebo-controlled, Global Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986446, an Anti-MTBR Tau Monoclonal Antibody, in Participants with Early Alzheimer’s Disease (TargetTau-1)

• Protocol code: CN008-0003
• EudraCT code: No aplica
• Research group: Neurovascular Diseases
• Service: Neurology
• Principal investigator:  Delgado Martínez, Maria Pilar
• Pathology: Malalties del sistema nerviós
• Phase: Fase II

A Randomized, Open-Label, Phase 2 Study Evaluating Abemaciclib in Combination With Temozolomide Compared to Temozolomide Monotherapy in Children and Young Adults With Newly Diagnosed High-Grade Glioma Following Radiotherapy

• Protocol code: I3Y-MC-JPEH
• EudraCT code: No aplica
• Research group: Childhood Cancer and Blood Disorders
• Service: Pediatric Oncohematology
• Principal investigator:  Llort Sales, Anna
• Pathology: Tumors
• Phase: Fase II

Efficacy and safety of co-administered cagrilintide and semaglutide (CagriSema)1.0 mg/1.0 mg s.c. once weekly versus tirzepatide 5 mg s.c. once weekly in participants with type 2diabetes inadequately controlled on metformin, SGLT2 inhibitor or both

• Protocol code: NN9388-7741
• EudraCT code: No aplica
• Research group: Diabetes and Metabolism
• Service: Endocrinology
• Principal investigator:  Ciudin Mihai, Andreea
• Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més
• Phase: Fase III