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Ensayo multinacional, abierto, aleatorizado y controlado para investigar la eficacia y la seguridad de NNC0365-3769 (Mim8) en adultos y adolescentes con hemofilia A con o sin inhibidores

  • Protocol code: NN7769-4514
  • EudraCT code: 2020-001048-24
  • Pathology: Hemofilia A con inhibidores
  • Pharmac: NNC0365-3769 (Mim8)
  • Promoter: Novo Nordisk A/S
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Fase III
  • Recruiting: Closed
  • Status: Cerrado

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Estudio abierto para investigar la eficacia, la seguridad y la farmacocinética de la profilaxis con concizumab en niños menores de 12 años con hemofilia A o B con o sin inhibidores

  • Protocol code: NN7415-4616
  • EudraCT code: 2020-000504-11
  • Pathology: Haemophilia A or B with or without inhibitors
  • Pharmac: Concizumab
  • Promoter: Novo Nordisk A/S
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Fase III
  • Recruiting: Open
  • Status: Activo

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Purpose: Request for information on VHIR clinical research.
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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
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A phase 3b open-label, multicenter study evaluating physicalactivity and joint health in previously treated patients =12 years of age with severehaemophilia A treated with intravenous recombinant coagulation factor VIII FcvonWillebrand Factor-XTEN fusion protein (rFVIIIFc-VWF-XTEN; efanesoctocogalfa) for 24 months.

  • Protocol code: BIVV001-001
  • EudraCT code: 2022-500275-31-00
  • Pathology: Haemophilia A
  • Pharmac: Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein (rFVIIIFc-VWF-XTEN; BIVV001)
  • Promoter: Swedish Orphan Biovitrum AB (publ) (Sweden)
  • Principal investigator:  Benitez Hidalgo, Olga
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Hematologia
  • Phase: Fase III
  • Recruiting: Closed
  • Status: Finalizado

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Estudio de dosis escalonadas para evaluar la farmacocinética, eficacia y seguridad de apotransferrina en pacientes con atransferrinemia.

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Estudio fase1/2, abierto, multicentrico, first in human para evualar la seguridad, tolerabilidad, pk y actividad atnitumoral de repotrectinib (TPX-0005) en pacientes con TSA y reordenamiento ALK, ROS1, o NTRK1-3 Rearrangements (TRIDENT-1)

  • Protocol code: TPX-0005-01
  • EudraCT code: 2016-003616-13
  • Pathology: Advanced solid tumors
  • Pharmac: TPX-0005
  • Promoter: Turning Point Therapeutics, Inc.
  • Principal investigator:  Felip Font, Enriqueta
  • Research group:  VHIO (Grups bàsics i clínics)
  • Service: Oncologia
  • Phase: Fase I
  • Recruiting: Open
  • Status: Activo

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Estudio fase 1b, abierto, de un solo brazo de tratamiento con Epcoritamab en pacientes pediátricos con neoplasias de células B maduras recidivantes/refractarias.

  • Protocol code: M20-429
  • EudraCT code: 2021-004555-16
  • Pathology: Relapsed/Refractory Aggressive Mature B-cell Neoplasms
  • Pharmac: Epcoritamab
  • Promoter: AbbVie Deutschland GmbH & Co. KG
  • Principal investigator:  Hladun Alvaro, Raquel
  • Research group:  Càncer i malalties hematològiques infantils
  • Service: Oncohematologia Pediàtrica
  • Phase: Fase I
  • Recruiting: Closed
  • Status: Cerrado

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FaR-RMS – Un estudio global para niños y adultos con Rabdomiosarcoma recién diagnosticado y recidivante

  • Protocol code: RG_17-247
  • EudraCT code: 2018-000515-24
  • Pathology: Rhabdoyosarcoma
  • Pharmac: Irinotecan with IVA (IrIVA).
  • Promoter: University of Birmingham
  • Principal investigator:  Hladun Alvaro, Raquel
  • Research group:  Càncer i malalties hematològiques infantils
  • Service: Oncohematologia Pediàtrica
  • Phase: Fase I
  • Recruiting: Open
  • Status: Activo

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Ensayo fase 1 / 2 para evaluar la seguridad y la eficacia de AZD0486 en pacientes adolescentes y adultos con leucemia linfoblástica aguda de células B en recaída o refractarios.

  • Protocol code: D7405C00001
  • EudraCT code: 2023-505840-20-00
  • Pathology: B-Cell Acute Lymphoblastic Leukaemia
  • Pharmac: AZD0486
  • Promoter: Astrazeneca AB (Sweden)
  • Principal investigator:  Barba Suñol, Pere
  • Research group:  Hematologia Experimental
  • Service: Hematologia
  • Phase: Fase I
  • Recruiting: Open
  • Status: Activo

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Estudio en fase III, aleatorizado, doble ciego, controlado con placebo y de dosis única para evaluar la eficacia y la seguridad de suvratoxumab en adultos y adolescentes con ventilación mecánica para la prevención de la neumonía nosocomial

  • Protocol code: AR-320-003
  • EudraCT code: 2021-004979-14
  • Pathology: Prevención de la neumonía nosocomial
  • Pharmac: Suvratoxumab
  • Promoter: Aridis Pharmaceuticals
  • Principal investigator:  Ferrer Roca, Ricard
  • Research group:  Shock, Disfunció Orgànica i Ressucitació
  • Service: UCI
  • Phase: Fase III
  • Recruiting: Closed
  • Status: Cerrado

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Protocolo NOPHO-DBH AML 2012 Estudio de investigación para el tratamiento de niños y adolescentes con leucemia mieloide aguda de 0 a 18 años.

  • Protocol code: NOPHO-DBH-AML-2012
  • EudraCT code: 2012-002934-35
  • Pathology: Acute Myeloid Leukemia (Pediatric 0-18 years)
  • Pharmac: NOPHO-DBH AML 2012 Protocol
  • Promoter: Västra Götaland Regionen
  • Principal investigator:  Murillo Sanjuán , Laura
  • Research group:  Càncer i malalties hematològiques infantils
  • Service: Oncohematologia Ped.
  • Phase: Fase III
  • Recruiting: Closed
  • Status: Finalizado

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
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The request for information on a research project or clinical trial does not entail inclusion in it.
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