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Jordi Barquinero Mañez

I am an MD, specialized in Internal Medicine, and senior researcher at the Vall d'Hebron Research Institute (VHIR). Doctor from the UAB with Extraordinary Award. I received post-doctoral training at the Fred Hutchinson Cancer Research Center (Seattle). I am currently leading the Gene and Cell Therapy group at the VHIR. My interest has focused on understanding disease mechanisms and finding effective therapies for orphan diseases. In our laboratory we have worked on gene therapy research projects for several rare diseases, mainly of genetic origin.

Institutions of which they are part

Head of group
Gene and Cell Therapy
Vall Hebron Institut de Recerca

Jordi Barquinero Mañez

Institutions of which they are part

Head of group
Gene and Cell Therapy
Vall Hebron Institut de Recerca

I am an MD, specialized in Internal Medicine, and senior researcher at the Vall d'Hebron Research Institute (VHIR). Doctor from the UAB with Extraordinary Award. I received post-doctoral training at the Fred Hutchinson Cancer Research Center (Seattle). I am currently leading the Gene and Cell Therapy group at the VHIR. My interest has focused on understanding disease mechanisms and finding effective therapies for orphan diseases. In our laboratory we have worked on gene therapy research projects for several rare diseases, mainly of genetic origin.

I am an MD specialized in Internal Medicine (Vall d'Hebron University Hospital). I worked at the Intensive Care Unit (HUVH) and the Emergency Department of the Hospital de l'Esperança. I did pre-doctoral studies on autoimmunity at the University of Louisville (Dr. N. Harris) and got my PhD at the Autonomous University of Barcelona with Extraordinary Award, with a work that contributed to the description of a new disease, the primary antiphospholipid syndrome. I was a postdoc at the Fred Hutchinson Cancer Research Center (Dr. R. Storb, Seattle), where I was trained in hematopoietic stem cell gene therapy. I am currently group leader of the gene and cell therapy group (VHIR), where we investigate new therapeutic strategies for rare genetic diseases, mostly in collaboration with other groups on campus and from other national and international institutions. We have participated in research projects using models of multiple sclerosis, hemophilia, MNGIE, in a clinical trial for Fanconi anemia type A (coordinated by Drs. J. Bueren and P. Río, at the CIEMAT (Madrid)), and more recently, in a novel gene therapy approach for muscular dystrophy due to merosin deficiency, in collaboration with the Pediatric Neurology group (Drs. F. Munell and D. Gómez). Our group is part of the national network TERAV (RICORS). I have participated in European projects (INHERINET, CONSERT), including one as coordinator (HEMO-IPS, e-Rare-2), in which we experimentally demonstrated the mutagenic mechanism of the "Royal disease", the form of hemophilia B that affected several European royal families in the 19th and 20th centuries. I participate as a teacher in different master's degrees and I am a member of the American and European Gene and Cell Therapy Societies, and was one of the founding members of the Spanish Society of Gene and Cell Therapy.

Projects

Nuevas aproximaciones experimentales para acelerar la recuperación postrasplante del componente linfoide del sistema hematopoyético humano

IP: Jordi Barquinero Mañez
Collaborators: Ramon Gimeno Martinez
Funding agency: Instituto de Salud Carlos III
Funding: 146036.97
Reference: MS04/00293
Duration: 11/03/2005 - 31/01/2011

Inducción de tolerancia en la encefalitis autoinmune experimental mediante terapia génica

IP: Jordi Barquinero Mañez
Collaborators: Herena Eixarch Ahufinger, Carmen Espejo Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 71300
Reference: PI020205
Duration: 06/11/2002 - 06/11/2005

Gene Therapy of Hematopoietic Stem cells for Inherited Diseases

IP: Jordi Barquinero Mañez
Collaborators: Francisco Vidal Pérez
Funding agency: EUROPEAN COMMISSION
Funding: 207199
Reference: QLK3-CT-2001-00427
Duration: 01/11/2001 - 31/10/2004

Desarrollo de modelos preclínicos de terapia géncia para enfermedades hereditarias

IP: -
Collaborators: Jordi Barquinero Mañez
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CP00/3047
Duration: 19/02/2001 - 18/01/2007

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