About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.
With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.
In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.
IP: Fernanda Raquel Da Silva Andrade
IP: Joaquin Seras Franzoso
IP: Maria del Pilar Reimundo Diaz-Fierros
IP: Ibane Abasolo Olaortua
IP: Joaquin Seras Franzoso Collaborators: Maria Fidel Lledò, Miriam Izquierdo Sans Funding agency: Instituto de Salud Carlos III Funding: 119567 Reference: FI23/00223 Duration: 15/01/2024 - 14/01/2028
IP: David Martinez Selva Collaborators: Maria Teresa Salcedo Allende, Lorena Ramos Pérez, Pablo Gabriel Medina Funding agency: Instituto de Salud Carlos III Funding: 190000 Reference: PI23/00544 Duration: 01/01/2024 - 31/12/2026
IP: Ibai Los Arcos Bertiz Collaborators: M Teresa Martin Gomez, Yolanda Villena Ortiz, Javier Gomis Rodriguez, Joan Gavaldà Santapau, Judith Sacanell Lacasa, Marta Zapata Ortega, Leire Sanchez Corujo Funding agency: Instituto de Salud Carlos III Funding: 37500 Reference: PI23/01467 Duration: 01/01/2024 - 31/12/2026
IP: Joaquin Seras Franzoso Collaborators: Diana Fernandes de Rafael Funding agency: Asociación Cáncer de Páncreas Funding: 50000 Reference: ACANPAN/PROJECTES/2023/SERAS Duration: 05/12/2023 - 04/12/2025
PMID: 37376135 Journal: Pharmaceutics Year: 2023 Reference: Pharmaceutics. 2023 Jun 8;15(6):1686. doi: 10.3390/pharmaceutics15061686. Impact factor: Publication type: Review in international publication Authors: Abasolo, Ibane; Andrade, Fernanda; Baranda-Martinez-Abascal, Diego; Carcavilla, Pilar; Diaz-Riascos, Zamira Vanessa; German-Cortes, Julia; Molto-Abad, Marc; Montero, Sara; Rafael, Diana; Seras-Franzoso, Joaquin et al. DOI: 10.3390/pharmaceutics15061686
PMID: 37443087 Journal: Orphanet Journal of Rare Diseases Year: 2023 Reference: Orphanet J Rare Dis. 2023 Jul 13;18(1):188. doi: 10.1186/s13023-023-02793-4. Impact factor: Publication type: Letter or abstract Authors: Argudo, Ana; Arranz, Jose Antonio; Artuch, Rafael; Carnicer, Clara; de Aledo-Castillo, Jose Manuel Gonzalez; de Los Santos, Mariela Mercedes; Fernandez, Rosa; Garcia-Cazorla, Angeles; Garcia-Villoria, Judit; Garcia-Volpe, Camila et al. DOI: 10.1186/s13023-023-02793-4
PMID: 37555464 Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Year: 2023 Reference: BJOG. 2023 Aug 9. doi: 10.1111/1471-0528.17631. Impact factor: Publication type: Paper in international publication Authors: Alsius, Merce; Bonacina, Erika; Caamina, Sara; Carreras, Elena; Castillo-Ribelles, Laura; de Mingo, Laura; Diaz, Sonia; Garcia, Esperanza; Garcia-Manau, Pablo; Lopez, Monica et al. DOI: 10.1111/1471-0528.17631
PMID: 37569568 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Jul 29;24(15):12183. doi: 10.3390/ijms241512183. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Borras, Francesc E; Burgui, Idoia; Camos, Silvia; Corrales, Irene; Costafreda, Maria Isabel; Domingo, Esteban; Esteban, Juan Ignacio; Llorens-Revull, Meritxell; Martinez-Gonzalez, Brenda et al. DOI: 10.3390/ijms241512183
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
During the last year, the collaboration between Vall d’Hebron and ZeClinics has found three nanobody candidates with potent anticancer properties in zebrafish model.
