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Clinical Pharmacology

The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.

The group is a Special Group of Research recognized by AGAUR GenCat.  It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut. 

Research lines

Efectividad, resultados y análisis beneficio/riesgo del uso de medicamentos en la práctica clínica habitual

In this line of research, studies of the use of drugs in real clinical practice are mainly carried out, such as monitoring the use of outpatient hospital drugs and medicines evaluated for their special conditions of use (e.g. off-label and compassionate use).


In addition, research is being carried out into the use of medicines within a European consortium led by Utrecht University EU PE&PV, and at the request of the European Medicines Agency (e.g. use of retinoids in women of childbearing age).

IP: Immaculada Danes Carreras, Mònica Sabaté Gallego

Epidemiology and pain treatment

Primarily focused on the analysis of acute and chronic postoperative pain and neuropathic pain.

IP: Francisco Javier Medel Rebollo

Pharmacovigilance

Analysis of the spontaneous reported adverse drug reactions at the Hospital, in order to improve knowledge of the safety profile of new commercialized drugs and to be able to estimate the incidence of their adverse drug reactions. Analysis of the drug use in the real world setting in order to improve the prevention of adverse drug reactions.

IP: Maria Antònia Agustí Escasany, Cristina Aguilera Martin

Acute renal failure

In collaboration with three hospitals of the Metropolitan Area of Barcelona the group performs two studies to identify hospital admissions due to acute renal failure and hospital-acquired acute renal failure related to rennin-angiotensin-aldosterone system and other drugs with in-hospital use. The aim is to estimate the incidence rate and the severity, to describe the clinic characteristics and clinical course, the drugs involved, other associated risk factors, the length of the hospital stay, and the economical impact.

IP: Maria Antònia Agustí Escasany

Blog

News

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The results show the need for continuous monitoring of patients to detect and manage possible adverse effects occurring months and years after treatment.

The creation of hybrid digital-human interaction spaces between avatars and people offers new opportunities for personalized medicine