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Clinical Pharmacology

The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.

The group is a Special Group of Research recognized by AGAUR GenCat.  It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut. 

Publications

Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage: a multicenter case-control study.

PMID: 35114859
Journal: ANNALS OF MEDICINE
Year: 2022
Reference: Ann Med. 2022 Dec;54(1):379-392. doi: 10.1080/07853890.2021.2016940.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Carmelo; Bacariza-Cortinas, Manuel; Estany-Gestal, Ana; Figueiras, Adolfo; Ibanez, Luisa; Ibarra-Garcia, Eguzkine; Macias-Garcia, Fernando; Mallah, Narmeen; Martin-Arias, Luis; Palacios-Zabalza, Itziar et al.
DOI: 10.1080/07853890.2021.2016940

Application of pharmacovigilance tools in a case of subacute anterior angle narrowing while under furosemide exposure.

PMID: 35078871
Journal: BMJ case reports
Year: 2022
Reference: BMJ Case Rep. 2022 Jan 25;15(1). pii: 15/1/e244581. doi: 10.1136/bcr-2021-244581.
Impact factor:
Publication type: Letter or abstract
Authors: Anderssen-Nordahl, Emilie; Gomez Munoz, Alicia; Perello Carrascosa, Manel; Riera-Arnau, Judit et al.
DOI: 10.1136/bcr-2021-244581

European association for clinical pharmacology and therapeutics young clinical pharmacologists working group: a cornerstone for the brighter future of clinical pharmacology.

PMID: 35037981
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2022
Reference: Eur J Clin Pharmacol. 2022 Apr;78(4):691-694. doi: 10.1007/s00228-022-03277-3. Epub 2022 Jan 17.
Impact factor:
Publication type: Paper in international publication
Authors: Alcubilla, Pau; Arellano, Ana Lucia; Belancic, Andrej; Jouanjus, Emilie; Nogueiras-Alvarez, Rita; Roncato, Rossana; Saez-Penataro, Joaquin; Sans-Pola, Carla; Zunic, Miodrag et al.
DOI: 10.1007/s00228-022-03277-3

Antidepressant Use and Stroke or Mortality Risk in the Elderly.

PMID: 34632668
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2022
Reference: Eur J Neurol. 2022 Feb;29(2):469-477. doi: 10.1111/ene.15137. Epub 2021 Oct 25.
Impact factor:
Publication type: Paper in international publication
Authors: Ballarin, Elena; Berger, Ursula; Ibanez, Luisa; Maisterra, Olga; On, Begum Irmak; Sabate, Monica; San-Jose, Antonio; Vidal, Xavier et al.
DOI: 10.1111/ene.15137

The relationship between the severity and mortality of SARS-CoV-2 infection and 25-hydroxyvitamin D concentration - a metaanalysis.

PMID: 33966262
Journal: Advances in respiratory medicine
Year: 2021
Reference: Adv Respir Med. 2021;89(2):145-157. doi: 10.5603/ARM.a2021.0037.
Impact factor:
Publication type: Review in international publication
Authors: Amado, Jose; Ghashut, Rawia A; Laird, Eamon; Oscanoa, Teodoro J; Romero-Ortuno, Roman; Vidal, Xavier et al.
DOI: 10.5603/ARM.a2021.0037

Genetic risk factors in drug-induced liver injury due to isoniazid-containing anti-tuberculosis drug regimens.

PMID: 33135175
Journal: CLINICAL PHARMACOLOGY & THERAPEUTICS
Year: 2021
Reference: Clin Pharmacol Ther. 2021 Apr;109(4):1125-1135. doi: 10.1002/cpt.2100. Epub 2020 Dec 5.
Impact factor:
Publication type: Paper in international publication
Authors: Aithal, Guruprasad P; Andrade, Raul J; Bjornsson, Einar; Daly, Ann K; Devarbhavi, Harshad; Eapen, Chundamannil E; Goel, Ashish; Grove, Jane I; Ibanez, Luisa; Larrey, Dominique et al.
DOI: 10.1002/cpt.2100

A case series of confusional states and other neurotoxic effects caused by ertapenem.

PMID: 33010054
Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2021
Reference: Br J Clin Pharmacol. 2021 Apr;87(4):2140-2145. doi: 10.1111/bcp.14582. Epub 2020 Nov 3.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, Antonia; Danes, Immaculada; Gracia, Rosa M; Perello, Manel; Perez, Eulalia; Pigrau, Carles; Sueiras, Maria et al.
DOI: 10.1111/bcp.14582

Integrated health intervention on polypharmacy and inappropriate prescribing in elderly people with multimorbidity: Results at the end of the intervention and at 6 months after the intervention.

PMID: 32593414
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 Mar 26;156(6):263-269. doi: 10.1016/j.medcli.2020.04.030. Epub 2020 Jun 24.
Impact factor:
Publication type: Paper in national publication
Authors: Agusti, Antonia; Gost, Jordi; Laorden, Helena; Oropeza, Vanessa; Perez-Bocanegra, Carmen; Romero, Rosa; San-Jose, Antonio; Vidal, Xavier et al.
DOI: 10.1016/j.medcli.2020.04.030

Blog

News

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The study by physician Emilie Anderssen seeks to optimize the medicalization of people living in nursing homes.