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Clinical Pharmacology

The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.

The group is a Special Group of Research recognized by AGAUR GenCat.  It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut. 

Publications

Indications related to antidepressant prescribing in the Nivel-PCD database and the SIDIAP database.

PMID: 35134393
Journal: JOURNAL OF AFFECTIVE DISORDERS
Year: 2022
Reference: J Affect Disord. 2022 Apr 15;303:131-137. doi: 10.1016/j.jad.2022.02.001. Epub 2022 Feb 5.
Impact factor: 4.839
Publication type: Paper in international publication
Authors: van Dijk, L; Camacho-Arteaga, L F; Gardarsdottir, H; Ibanez, L; Souverein, P C; Ballarin, E; Sabate, M; Vidal, X; Hek, K et al.
DOI: 10.1016/j.jad.2022.02.001

Regulatory and clinical development to support the approval of advanced therapies medicinal products in Japan.

PMID: 35762253
Journal: EXPERT OPINION ON BIOLOGICAL THERAPY
Year: 2022
Reference: Expert Opin Biol Ther. 2022 Jul;22(7):831-842. doi: 10.1080/14712598.2022.2093637. Epub 2022 Jul 4.
Impact factor: 4.388
Publication type: Paper in international publication
Authors: Antonio, Vallano; Merce, Obach; Antonia, Agusti; Carolina, Iglesias-Lopez et al.
DOI: 10.1080/14712598.2022.2093637

Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study.

PMID: 35795713
Journal: EClinicalMedicine
Year: 2022
Reference: EClinicalMedicine. 2022 Jul 1;50:101529. doi: 10.1016/j.eclinm.2022.101529. eCollection 2022 Aug.
Impact factor: 0
Publication type: Paper in international publication
Authors: Castano, Luis; Borobia, Alberto M; Castillo de la Osa, Maria; Gonzalez-Perez, Maria; Garcia-Perez, Javier; Bertran, Maria Jesus; Campins, Magdalena; Lora, David; Perez-Olmeda, Mayte; Alcami, Jose et al.
DOI: 10.1016/j.eclinm.2022.101529

Impact of home CPAP treated obstructive sleep apnea on COVID-19 outcomes in hospitalized patients.

PMID: 35404224
Journal: Journal of Clinical Sleep Medicine
Year: 2022
Reference: J Clin Sleep Med. 2022 Jul 1;18(7):1857-1864. doi: 10.5664/jcsm.10016.
Impact factor: 4.062
Publication type: Paper in international publication
Authors: Sampol, Julia, Saez, Maria, Marti, Sergi, Pallero, Mercedes, Barrecheguren, Miriam, Ferrer, Jaume, Sampol, Gabriel, Vimes Fortis, Alba, Guillen Del Castillo, Alfredo, et al.
DOI: 10.5664/jcsm.10016

Comparison of regulatory pathways for the approval of advanced therapies in the European Union and the United States.

PMID: 33483292
Journal: CYTOTHERAPY
Year: 2021
Reference: Cytotherapy. 2021 Mar;23(3):261-274. doi: 10.1016/j.jcyt.2020.11.008. Epub 2021 Jan 19.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, Antonia; Iglesias-Lopez, Carolina; Obach, Merce; Vallano, Antonio et al.
DOI: 10.1016/j.jcyt.2020.11.008

Progressive multifocal leukoencephalopathy in the era of new disease-modifying treatments for multiple sclerosis.

PMID: 33431183
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 May 21;156(10):509-514. doi: 10.1016/j.medcli.2020.10.015. Epub 2021 Jan 9.
Impact factor:
Publication type: Paper in national publication
Authors: Bosch Ferrer, Montserrat; Filippi-Arriaga, Francesca; Riera-Arnau, Judit; Rodriguez-Acevedo, Breogan et al.
DOI: 10.1016/j.medcli.2020.10.015

COVID-19 in Solid Organ Transplantation: A Matched Retrospective Cohort Study and Evaluation of Immunosuppression Management.

PMID: 32941394
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Jan 1;105(1):138-150. doi: 10.1097/TP.0000000000003460.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Martinez, Carla; Anton, Andres; Berastegui, Cristina; Castells, Lluis; Del-Rio-Gutierrez, Jose-Manuel; Domenech, Laura; Garcia-Garcia, Sonia; Garcia-Ortega, Patricia; Gomez-Ganda, Laura; Gorgas-Torner, Maria-Queralt et al.
DOI: 10.1097/TP.0000000000003460

COVID-19 Clinical Profile in Latin American Migrants Living in Spain: Does the Geographical Origin Matter?

PMID: 34830495
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Nov 9;10(22). pii: jcm10225213. doi: 10.3390/jcm10225213.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Sempere, Abiu, Salvador, Fernando, Monforte, Arnau, Sampol, Julia, Espinosa-Pereiro, Juan, Miarons, Marta, Bosch-Nicolau, Pau, Guillen-Del-Castillo, Alfredo, Aznar, Maria Luisa, Campos-Varela, Isabel et al.
DOI: 10.3390/jcm10225213

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