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Diagnostic Nanotools (DINA)

At Diagnostic Nanotools, we work to ameliorate the diagnosis of diseases. On the one hand, we produce rapid assays and electrochemical biosensors, with a special emphasis on point-of-care diagnosis of infectious diseases.

In this context, we develop single-step immunoassays, classical biosensors (in which a sensor is modified with bioreceptors for the specific detection of the analyte of interest) and magneto-biosensors (in which the assay is performed on magnetic particles). We explore the implementation of nanomaterials to obtain improved transducers and as signal amplifiers to generate faster and more sensitive biosensors. We also seek to automate the tests using extremely simple and economical paper microfluidics. On the other hand, we are developing "synthrocytes," a synthetic reagent that could replace animal erythrocytes in the hemagglutination assays used currently for the global surveillance of influenza viruses and in the control of vaccine production.

Team

Eva Baldrich Rubio

Eva Baldrich Rubio

Head of group
Diagnostic nanotools (DINA)
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Briza Pérez López

Briza Pérez López

Postdoctoral researcher
Diagnostic nanotools (DINA)
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Judit Prat Trunas

Judit Prat Trunas

Main researcher
Diagnostic nanotools (DINA)
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Haridian Tato Mateo

Haridian Tato Mateo

Research technician
Diagnostic nanotools (DINA)
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Menyar Ben Jaballah

Menyar Ben Jaballah

Postdoctoral researcher
Diagnostic nanotools (DINA)
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Maria Urpí Castany

Maria Urpí Castany

Research technician
Diagnostic nanotools (DINA)
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Eva Baldrich Rubio

Eva Baldrich Rubio

Head of group
Diagnostic nanotools (DINA)
Read more
Briza Pérez López

Briza Pérez López

Postdoctoral researcher
Diagnostic nanotools (DINA)
Read more
Judit Prat Trunas

Judit Prat Trunas

Main researcher
Diagnostic nanotools (DINA)
Read more
Haridian Tato Mateo

Haridian Tato Mateo

Research technician
Diagnostic nanotools (DINA)
Read more
Menyar Ben Jaballah

Menyar Ben Jaballah

Postdoctoral researcher
Diagnostic nanotools (DINA)
Read more
Maria Urpí Castany

Maria Urpí Castany

Research technician
Diagnostic nanotools (DINA)
Read more

Projects

Paper-based dry-storage reagent integration into point-of-care diagnostic devices for infectious diseases.

IP: Eva Baldrich Rubio
Collaborators: Judit Prat Trunas, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 14835
Reference: MV23/00042
Duration: 08/03/2024 - 14/07/2024

CATMAL - Compact Analytical Tool for robust MALaria decentralized diagnosis and community surveillance

IP: Eva Baldrich Rubio
Collaborators: Francesc Zarzuela Serrat, Israel Molina Romero, Maria Urpí Castany, Adrián Sánchez Montalvá, Elena Sulleiro Igual, Judit Prat Trunas, Ines Mercedes Oliveira Souto, Briza Pérez López
Funding agency: Fundació "La Caixa"
Funding: 392205
Reference: HR23-00679
Duration: 01/12/2023 - 30/11/2026

Grups de Recerca Consolidats

IP: Eva Baldrich Rubio
Collaborators: Judit Prat Trunas, Cristina Andrés Vergés, Briza Pérez López
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00617
Duration: 01/01/2022 - 30/06/2025

Desenvolupament de dispositius diagnòstics

IP: Eva Baldrich Rubio
Collaborators: Judit Prat Trunas, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 89900
Reference: IFI22/00017
Duration: 01/01/2023 - 31/12/2026

Publications

Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?

PMID: 37027026
Journal: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
Year: 2023
Reference: Eur Child Adolesc Psychiatry. 2023 Apr 7. doi: 10.1007/s00787-023-02196-7.
Impact factor:
Publication type: Paper in international publication
Authors: Amoretti, Silvia; Ayora, Miriam; Baeza, Inmaculada; Balanza-Martinez, Vicent; Bernardo, Miquel; Bioque, Miquel; Butjosa, Anna; Casanovas, Francesc; Castro-Fornieles, Josefina; Contreras, Fernando et al.
DOI: 10.1007/s00787-023-02196-7

Paper-based microfluidic electro-analytical device (PMED) for magneto-assay automation: Towards generic point-of-care diagnostic devices.

PMID: 38039728
Journal: BIOSENSORS & BIOELECTRONICS
Year: 2023
Reference: Biosens Bioelectron. 2023 Nov 26;246:115875. doi: 10.1016/j.bios.2023.115875.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Carulla, A; Arias-Alpizar, K; Baldrich, E; Colomer-Farrarons, J; Del Campo, F J; Miribel-Catala, P Ll; Molina, I; Orio-Tejada, J; Prat-Trunas, J; Sanchez-Montalva, A et al.
DOI: 10.1016/j.bios.2023.115875

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The head of the Diagnostic Nanotools (DINA) group was part of a Spanish delegation that also participated in activities to establish contracts between national and international centers.

A project to develop a compact, inexpensive and easy to use device for mass screening for malaria.