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Hepato-bilio-pancreatic surgery (HBP) and liver transplantation

Until 2017, this group was constituted as a consolidated group in the VHIR under the name of "Digestive Transplants" with a consolidated research trajectory. Our group has two large areas of research: liver transplantation, which is cross-sectional adult-pediatric and; on the other hand, research, specifically in the fields of liver resections, liver cancer (primary or metastatic), biliary cancer, pancreatic cancer and pancreatitis. Both areas have very innovative aspects, with translational objectives, including artificial intelligence, transcriptomics and molecular biology.

The general objective of the liver transplant research area is to improve the preservation of liver grafts, as well as increase the survival of grafts and transplant patients. The research area related to cancer or acute pancreatitis has as a general objective to improve the management and treatment of patients with pancreatitis, as well as to improve the diagnosis and survival of cancer patients.

Team

Maria Margaret Mercadal Hally

Maria Margaret Mercadal Hally

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Mireia Caralt Barba

Mireia Caralt Barba

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Ramon Charco Torra

Ramon Charco Torra

Head of group
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Maria Margaret Mercadal Hally

Maria Margaret Mercadal Hally

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Mireia Caralt Barba

Mireia Caralt Barba

Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Ramon Charco Torra

Ramon Charco Torra

Head of group
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more

Research lines

Nous escores predictius i factors de mal pronòstic en la pancreatitis aguda

IP: Elizabeth Pando Rau, Joaquin Balsells Valls

Noves indicacións en el camp del transplant oncology

Colangiocarcinoma intrahepatic i perihiliar i les metàstasis hepàtiques colo-rectals irresecables.

IP: Cristina Dopazo Taboada, Ramon Charco Torra

Perfils moleculars en metàstasis hepàtiques colorectals respectables

Té com a objectiu avaluar el pronòstic en l'entorn preoperatori en comparació amb els factors clínics i histològics.

IP: Cristina Dopazo Taboada, Ramon Charco Torra

Sarcopènia i càncer de pàncrees

IP: Elizabeth Pando Rau, Joaquin Balsells Valls

Publications

Intraductal papillary neoplasms of the bile duct: A European retrospective multicenter observational study (EUR-IPNB Study).

PMID: 36917142
Journal: International Journal of Surgery
Year: 2023
Reference: Int J Surg. 2023 Mar 15. doi: 10.1097/JS9.0000000000000280.
Impact factor:
Publication type: Paper in international publication
Authors: Achalandabaso, Mar; Achalandabaso, Mar; Alcazar-Lopez, Candido F; Alsammani, Mohammedsuror; Amaral, Maria Joao; Andersson, Bodil; Asbun, Horacio; Balakrishnan, Anita; Berrevoet, Frederik; Bjornsson, Bergthor et al.
DOI: 10.1097/JS9.0000000000000280

Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients.

PMID: 36949385
Journal: BMC GASTROENTEROLOGY
Year: 2023
Reference: BMC Gastroenterol. 2023 Mar 23;23(1):81. doi: 10.1186/s12876-023-02730-6.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, Joaquim; Barros, Marta; Blanco, Laia; Charco, Ramon; Fernandes, Nair; Herms, Daniel; Hidalgo, Nils Jimmy; Mata, Rodrigo; Pando, Elizabeth; Villasante, Sara et al.
DOI: 10.1186/s12876-023-02730-6

Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period.

PMID: 36987799
Journal: Experimental and Clinical Transplantation
Year: 2023
Reference: Exp Clin Transplant. 2023 Mar;21(3):236-244. doi: 10.6002/ect.2022.0412.
Impact factor:
Publication type: Paper in international publication
Authors: Castells, Lluis; Dopazo, Cristina; Len, Oscar; Llado, Laura; Los-Arcos, Ibai; Lung, Mayli; Nuvials, Xavier; Oriol, Isabel; Perez-Cameo, Cristina; Sabe, Nuria et al.
DOI: 10.6002/ect.2022.0412

Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry.

PMID: 37028826
Journal: HPB
Year: 2023
Reference: HPB (Oxford). 2023 Apr;25(4):400-408. doi: 10.1016/j.hpb.2022.07.015. Epub 2022 Aug 17.
Impact factor:
Publication type: Paper in international publication
Authors: Abu Hilal, Mohammed; Balsells, Joaquim; Berrevoet, Frederik; Besselink, Marc G; Bjornsson, Bergthor; Boggi, Ugo; Bratlie, Svein O; Burdio, Fernando; Cabus, Santiago S; Can, Mehmet F et al.
DOI: 10.1016/j.hpb.2022.07.015

Laparoscopic intragastric approach to transgastric necrosectomy.

PMID: 34855268
Journal: Journal of Hepato-Biliary-Pancreatic Sciences
Year: 2022
Reference: J Hepatobiliary Pancreat Sci. 2022 Aug;29(8):e75-e76. doi: 10.1002/jhbp.1086. Epub 2021 Dec 14.
Impact factor:
Publication type: Paper in international publication
Authors: D'Angelo, E; Dopazo, C; Lopez, R; Puig, O; Vellalta, G; Vidal, L et al.
DOI: 10.1002/jhbp.1086

Ultra Deep Sequencing of Circulating Cell-Free DNA as a Potential Tool for Hepatocellular Carcinoma Management.

PMID: 36010868
Journal: Cancers
Year: 2022
Reference: Cancers (Basel). 2022 Aug 11;14(16). pii: cancers14163875. doi: 10.3390/cancers14163875.
Impact factor:
Publication type: Paper in international publication
Authors: Bermudez-Ramos, Maria; Bilbao, Itxarone; Gregori, Josep; Guerrero-Murillo, Mercedes; Higuera, Monica; Martinez-Camprecios, Joan; Merino, Xavier; Minguez, Beatriz; Quer, Josep; Rodriguez-Frias, Francisco et al.
DOI: 10.3390/cancers14163875

Alternatives to left lateral sector in paediatric liver transplantation-a systematic review on monosegmental and reduced grafts.

PMID: 36016740
Journal: Hepatobiliary Surgery and Nutrition
Year: 2022
Reference: Hepatobiliary Surg Nutr. 2022 Aug;11(4):567-576. doi: 10.21037/hbsn-20-792.
Impact factor:
Publication type: Review in international publication
Authors: Gavriilidis, Paschalis; Hidalgo, Ernest et al.
DOI: 10.21037/hbsn-20-792

Benchmarking of minimally invasive distal pancreatectomy with splenectomy: European multicentre study.

PMID: 35834788
Journal: British Journal of Surgery
Year: 2022
Reference: Br J Surg. 2022 Oct 14;109(11):1124-1130. doi: 10.1093/bjs/znac204.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Sarireh, Bilal; Bassi, Claudio; Besselink, Marc; Bjornsson, Bergthor; Boggi, Ugo; Burdio, Fernando; Butturini, Giovanni; Capretti, Giovanni; Casadei, Riccardo; Coratti, Andrea et al.
DOI: 10.1093/bjs/znac204

Changes in Humoral Immune Response after SARS-CoV-2 Infection in Liver Transplant Recipients Compared to Immunocompetent Patients.

PMID: 33835707
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2021
Reference: Am J Transplant. 2021 Aug;21(8):2876-2884. doi: 10.1111/ajt.16599. Epub 2021 Apr 27.
Impact factor:
Publication type: Letter whit IF
Authors: Alamo-Martinez, Jose Maria; Alonso-Fernandez, Roberto; Arias-Milla, Ana; Blanco-Fernandez, Gerardo; Bustamante, Francisco Javier; Caballero-Marcos, Aranzazu; Cachero, Alba; Calatayud, Laura; Castells, Lluis; Colmenero, Jordi et al.
DOI: 10.1111/ajt.16599

Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers-A Prospective Observational Study.

PMID: 33824864
Journal: Canadian Journal of Gastroenterology and Hepatology
Year: 2021
Reference: Can J Gastroenterol Hepatol. 2021 Mar 22;2021:6643595. doi: 10.1155/2021/6643595. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Alberti, Piero; Balsells, Joaquim; Blanco, Laia; Caralt, Mireia; Charco, Ramon; Cirera, Arturo; Dopazo, Cristina; Gomez, Concepcion; Gomez, Maria Jose; Mata, Rodrigo et al.
DOI: 10.1155/2021/6643595

Percutaneous tibial nerve stimulation in patients with severe low anterior resection syndrome: randomized clinical trial.

PMID: 33793754
Journal: BRITISH JOURNAL OF SURGERY
Year: 2021
Reference: Br J Surg. 2021 Apr 30;108(4):380-387. doi: 10.1093/bjs/znaa171.
Impact factor:
Publication type: Paper in international publication
Authors: Alberti, P; Blanco, A; Espin-Basany, E; Fraccalvieri, D; Frago, R; Jimenez, L M; Marinello, F G; Ostiz, F; Pellino, G; Talavera, E et al.
DOI: 10.1093/bjs/znaa171

Recommendations and guidance on nutritional supplementation in the liver transplant setting.

PMID: 33724244
Journal: TRANSPLANTATION
Year: 2021
Reference: Transplantation. 2021 Dec 1;105(12):2528-2537. doi: 10.1097/TP.0000000000003736.
Impact factor:
Publication type: Review in international publication
Authors: Augustin, Salvador; Campos-Varela, Isabel; Gomez-Gavara, Concepcion et al.
DOI: 10.1097/TP.0000000000003736

Ampulloma in a Patient with a History of Roux-en-Y Gastrojejunal Bypass.

PMID: 32067701
Journal: CIRUGIA ESPANOLA
Year: 2020
Reference: Cir Esp. 2020 Dec;98(10):634-636. doi: 10.1016/j.ciresp.2019.12.013. Epub 2020 Feb 14.
Impact factor:
Publication type: Letter whit IF
Authors: Adell, Montse; Curell, Anna; Gomez-Gavara, Concepcion; Merino, Xavier; Pando, Elizabeth; Pando, Elizabeth et al.
DOI: 10.1016/j.ciresp.2019.12.013

Pancreatic cancer risk in relation to lifetime smoking patterns, tobacco type, and dose-response relationships.

PMID: 32051190
Journal: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
Year: 2020
Reference: Cancer Epidemiol Biomarkers Prev. 2020 May;29(5):1009-1018. doi: 10.1158/1055-9965.EPI-19-1027. Epub 2020 Feb 12.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, Joaquim; Barbera, Victor M; Carrato, Alfredo; Costello, Eithne; Crnogorac-Jurcevic, Tatjana; Dominguez-Munoz, Enrique; Farre, Antoni; Gomez-Rubio, Paulina; Greenhalf, William; Gress, Thomas M et al.
DOI: 10.1158/1055-9965.EPI-19-1027

Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors.

PMID: 32024476
Journal: BMC CANCER
Year: 2020
Reference: BMC Cancer. 2020 Feb 5;20(1):99. doi: 10.1186/s12885-020-6597-x.
Impact factor:
Publication type: Paper in international publication
Authors: Arribas, Joaquin; Carles, Joan; Castro, Sandra; Dopazo, Cristina; Fletcher, Jonathan A; Garcia-Valverde, Alfonso; George, Suzanne; Landolfi, Stefania; Lopez-Pousa, Antonio; Mancuso, Francesco M et al.
DOI: 10.1186/s12885-020-6597-x

Blog

News

The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The study also linked improved microbiota diversity to better liver function.