Infectious Diseases

The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.

The group's lines of research are mainly focused on four areas:

Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.

Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).

Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.

Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.

Projects

Aquest any no hi ha projectes actius.

Publications

Exploratory study of an oral screening dysplasia program for HIV-infected men who have sex with men.

PMID: 35730367
Journal: AIDS
Year: 2022
Reference: AIDS. 2022 Jun 23. pii: 00002030-990000000-00044. doi: 10.1097/QAD.0000000000003287.
Impact factor: 4.177
Publication type: Paper in international publication
Authors: Planas, Bibiana; Garcia, Jorge; Hernandez-Losa, Javier; Molina, Maria Del Mar; Dinares, Maria Carme; Callejo, Angela; Curran, Adria; Navarro, Jordi; Suanzes, Paula; Falco, Vicenc et al.
DOI: 10.1097/QAD.0000000000003287

Early outcomes in adults hospitalized with severe SARS-CoV-2 infection receiving tocilizumab.

PMID: 35755602
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin. 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcle.2021.06.023. Epub 2022 Jun 18.
Impact factor: 1.725
Publication type: Paper in international publication
Authors: Sellares-Nadal, Julia; Almirante, Benito; Guillen-Del-Castillo, Alfredo; Sampol, Julia; Augustin, Salvador; Bosch-Nicolau, Pau; Monforte-Pallares, Arnau; Sempere-Gonzalez, Abiu; Eremiev-Eremiev, Simeon; Miarons, Marta et al.
DOI: 10.1016/j.medcle.2021.06.023

[Consensus document for the management of schistosomiasis in Primary Care].

PMID: 35753207
Journal: Atencion Primaria
Year: 2022
Reference: Aten Primaria. 2022 Jun 23;54(8):102408. doi: 10.1016/j.aprim.2022.102408.
Impact factor: 1.137
Publication type: Paper in national publication
Authors: Salas-Coronas, Joaquin; Perez Perez, Alejandra; Roure, Silvia; Sanchez Peinador, Carmen; Santos Larregola, Laura; Arranz Izquierdo, Javier; Bocanegra, Cristina; Garcia Lopez Hortelano, Milagros; Garcia Vazquez, Elisa; Moza Morinigo, Helena et al.
DOI: 10.1016/j.aprim.2022.102408

Transforming a public university hospital and its area of influence into a comprehensive resource in response to the COVID-19 pandemic.

PMID: 35780057
Journal: Journal of healthcare quality research
Year: 2022
Reference: J Healthc Qual Res. 2022 Mar 10. pii: S2603-6479(22)00012-4. doi: 10.1016/j.jhqr.2022.02.006.
Impact factor: 0
Publication type: Paper in international publication
Authors: Rodriguez, I; Barba, M-A; Cebrian, R; Abadias, M-J; Aller, M-B; Cossio-Gil, Y; Roman, A; Dominguez, J-M; Campins, M; Martinez, J et al.
DOI: 10.1016/j.jhqr.2022.02.006

Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: results from the Brazilian COVID-19 Registry.

PMID: 33444752
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2021
Reference: Int J Infect Dis. 2021 Jun;107:300-310. doi: 10.1016/j.ijid.2021.01.019. Epub 2021 Jan 12.
Impact factor:
Publication type: Paper in international publication
Authors: do Nascimento, Israel J Borges; Etges, Ana Paula B S; Marcolino, Milena S; Martins, Karina P M P; Molina, Israel; Monteiro, Luanna S; Oliveira, Luana M; Polanczyk, Carisi A; Ruschel, Karen B; Sales, Thais L S et al.
DOI: 10.1016/j.ijid.2021.01.019

Impact of placental malaria on maternal, placental and fetal cord responses and its role in pregnancy outcomes in women from Blue Nile State, Sudan.

PMID: 33422078
Journal: MALARIA JOURNAL
Year: 2021
Reference: Malar J. 2021 Jan 9;20(1):35. doi: 10.1186/s12936-021-03580-x.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelrahim, Mutasim; Adam, Ishag; Franco-Jarava, Clara; Molina, Israel; Noureldien, Ali; Omer, Mona; Omer, Samia et al.
DOI: 10.1186/s12936-021-03580-x

Inherited GATA2 Deficiency Is Dominant by Haploinsufficiency and Displays Incomplete Clinical Penetrance.

PMID: 33417088
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Clin Immunol. 2021 Apr;41(3):639-657. doi: 10.1007/s10875-020-00930-3. Epub 2021 Jan 8.
Impact factor:
Publication type: Paper in international publication
Authors: Abel, Laurent; Alejo, Noe Ramirez; Ardeniz, Fatma Omur; Arias, Andres Augusto; Bellanne-Chantelot, Christine; Berron-Ruiz, Laura; Boisson-Dupuis, Stephanie; Branco, Lidia; Brunel, Anne-Sophie; Bustamante, Jacinta et al.
DOI: 10.1007/s10875-020-00930-3

Secular trends in the epidemiology and clinical characteristics of Enterococcus faecalis infective endocarditis at a referral center (2007-2018).

PMID: 33404892
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2021
Reference: Eur J Clin Microbiol Infect Dis. 2021 Jun;40(6):1137-1148. doi: 10.1007/s10096-020-04117-x. Epub 2021 Jan 6.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Escola-Verge, Laura; Fernandez-Galera, Ruben; Fernandez-Hidalgo, Nuria; Larrosa, Maria Nieves et al.
DOI: 10.1007/s10096-020-04117-x

Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

PMID: 32960957
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2020
Reference: Clin Infect Dis. 2020 Dec 31;71(11):2905-2916. doi: 10.1093/cid/ciaa696.
Impact factor: 8.313
Publication type: Paper in international publication
Authors: Vourli, Georgia, Noori, Teymur, Pharris, Anastasia, Porter, Kholoud, Axelsson, Maria, Begovac, Josip, Cazein, Francoise, Costagliola, Dominique, Cowan, Susan, Croxford, Sara et al.
DOI: 10.1093/cid/ciaa696

Efficacy and safety of hydroxychloroquine in healthcare professionals with mild SARS-CoV-2 infection: Prospective, non-randomized trial.

PMID: 33413989
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2020 Dec 9. pii: S0213-005X(20)30413-4. doi: 10.1016/j.eimc.2020.10.023.
Impact factor: 1.654
Publication type: Paper in national publication
Authors: Alonso, Manuel, Espuga, Meritxell, Esperalba, Juliana, Gorgas, M feminine Queralt, Almirante, Benito, Ribera, Esteban, Andres, Cristina, Vidal, Xavier, Anton, Andres, Agusti, Antonia et al.
DOI: 10.1016/j.eimc.2020.10.023

High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients.

PMID: 33166788
Journal: EBioMedicine
Year: 2020
Reference: EBioMedicine. 2020 Dec;62:103077. doi: 10.1016/j.ebiom.2020.103077. Epub 2020 Nov 6.
Impact factor: 5.736
Publication type: Paper in international publication
Authors: Domingo, Pere, Ceausu, Andra, Pacheco, Yolanda Maria, Veloso, Sergi, Inciarte, Alexy, Vidal-Gonzalez, Judit, Peraire, Maria, Perpinan, Carles, Falco, Vicenc, Masip, Jenifer et al.
DOI: 10.1016/j.ebiom.2020.103077

Telemedicine experience between two hospitals from Angola and Spain.

PMID: 33161918
Journal: INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
Year: 2020
Reference: Int J Technol Assess Health Care. 2020 Dec;36(6):545-548. doi: 10.1017/S0266462320000847. Epub 2020 Nov 9.
Impact factor: 1.494
Publication type: Paper in international publication
Authors: Sanchez-Montalva, Adrian, Bosch-Nicolau, Pau, Molina, Israel, Cossio, Yolima, Lopez, Teresa, Mateus, Raquel M feminine, Gil-Olivas, Eva, Salvador, Fernando, Moreno, Milagros, Bocanegra, Cristina et al.
DOI: 10.1017/S0266462320000847

Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles.

PMID: 30583020
Journal: MICROBIAL PATHOGENESIS
Year: 2019
Reference: Microb Pathog. 2019 Mar;128:112-118. doi: 10.1016/j.micpath.2018.12.019. Epub 2018 Dec 21.
Impact factor: 2.581
Publication type: Paper in international publication
Authors: Calbo, E, Martinez, J A, Marco, F, Chaves, F, Lagarde, M, Lopez-Medrano, F, Montejo, J M, Bereciertua, E, Hernandez, J L, von Wichmann, M A et al.
DOI: 10.1016/j.micpath.2018.12.019

Executive summary of the GeSIDA/National AIDS Plan consensus document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2018).

PMID: 29759422
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2019
Reference: Enferm Infecc Microbiol Clin. 2019 Mar;37(3):195-202. doi: 10.1016/j.eimc.2018.02.010. Epub 2018 Jun 18.
Impact factor: 1.685
Publication type: Paper in international publication
Authors: Perez-Molina, Jose A, Polo, Rosa, Lopez-Aldeguer, Jose, Lozano, Fernando, Aguirrebengoa, Koldo, Arribas, Jose Ramon, Boix, Vicente, Rivero, Antonio, Rubio, Rafael, Santos, Jesus et al.
DOI: 10.1016/j.eimc.2018.02.010

Multidrug (MDR) and extensively drug resistant (XDR) Gram negative prosthetic joint infections (PJI): Role of surgery and impact of colistin administration.

PMID: 30395988
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2019
Reference: Int J Antimicrob Agents. 2019 Mar;53(3):294-301. doi: 10.1016/j.ijantimicag.2018.10.018. Epub 2018 Nov 3.
Impact factor: 4.615
Publication type: Paper in international publication
Authors: Tattevin, Pierre, Papadopoulos, Antonios, Ribera, Alba, Mavrogenis, Andreas, Rodriguez-Pardo, Dolors, Bonnet, Eric, Salles, Mauro Jose, Dolores Del Toro, Maria, Nguyen, Sophie, Garcia, Antonio Blanco et al.
DOI: 10.1016/j.ijantimicag.2018.10.018

International mass gatherings and travel-associated illness: A GeoSentinel cross-sectional, observational study.

PMID: 31707112
Journal: Travel Medicine and Infectious Disease
Year: 2019
Reference: Travel Medicine and Infectious Disease. 2019 Nov;32:101504.. doi: 10.1016/j.tmaid.2019.101504.
Impact factor: 4.868
Publication type: Paper in international publication
Authors: Gautret, Philippe, Angelo, Kristina M, Asgeirsson, Hilmir, Duvignaud, Alexandre, van Genderen, Perry J J, Bottieau, Emmanuel, Chen, Lin H, Parker, Salim, Connor, Bradley A, Barnett, Elizabeth D et al.
DOI: 10.1016/j.tmaid.2019.101504

The challenge of discordant serology in Chagas Disease: The role of two confirmatory techniques in inconclusive cases.

PMID: 29775566
Journal: ACTA TROPICA
Year: 2018
Reference: Acta Trop. 2018 Sep;185:144-148. doi: 10.1016/j.actatropica.2018.05.010. Epub 2018 May 15.
Impact factor: 2.509
Publication type: Paper in international publication
Authors: Moure, Zaira, Sulleiro, Elena, Iniesta, Laura, Guillen, Carmen, Molina, Israel, Alcover, M Magdalena, Riera, Cristina, Pumarola, Tomas, Fisa, Roser et al.
DOI: 10.1016/j.actatropica.2018.05.010

Candida periprosthetic joint infection: a rare and difficult-to-treat infection.

PMID: 29746950
Journal: JOURNAL OF INFECTION
Year: 2018
Reference: J Infect. 2018 Aug;77(2):151-157. doi: 10.1016/j.jinf.2018.03.012. Epub 2018 May 8.
Impact factor: 4.603
Publication type: Paper in international publication
Authors: Ariza, Javier, Escola-Verge, Laura, Rodriguez-Pardo, Dolors, Lora-Tamayo, Jaime, Morata, Laura, Murillo, Oscar, Vilchez, Helem, Sorli, Luisa, Carrion, Laura Guio, Barbero, Jose M feminine et al.
DOI: 10.1016/j.jinf.2018.03.012

Ulcerated nodule on the neck: Syphilitic chancre.

PMID: 29731137
Journal: MEDICINA CLINICA
Year: 2018
Reference: Med Clin (Barc). 2018 Dec 21;151(12):e73. doi: 10.1016/j.medcli.2018.03.020. Epub 2018 May 3.
Impact factor: 1.168
Publication type: Paper in national publication
Authors: Iglesias-Plaza, Ana, Arando, Maider et al.
DOI: 10.1016/j.medcli.2018.03.020

The impact of deep surgical site infection on surgical outcomes after posterior adult spinal deformity surgery: a matched control study.

PMID: 29728924
Journal: EUROPEAN SPINE JOURNAL
Year: 2018
Reference: Eur Spine J. 2018 Oct;27(10):2518-2528. doi: 10.1007/s00586-018-5583-3. Epub 2018 May 4.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Haddad, Sleiman, Nunez-Pereira, Susana, Pigrau, Carlos, Rodriguez-Pardo, Dolors, Vila-Casademunt, Alba, Alanay, Ahmet, Acaroglu, Emre R, Kleinstueck, Frank S, Obeid, Ibrahim, Perez-Grueso, Francisco Javier Sanchez et al.
DOI: 10.1007/s00586-018-5583-3

Empiric Therapy With Carbapenem-Sparing Regimens for Bloodstream Infections due to Extended-Spectrum beta-Lactamase-Producing Enterobacteriaceae: Results From the INCREMENT Cohort.

PMID: 29020250
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2017
Reference: Clin Infect Dis. 2017 Oct 30;65(10):1615-1623. doi: 10.1093/cid/cix606.
Impact factor: 8.216
Publication type: Paper in international publication
Authors: Gutierrez-Gutierrez, Belen, Palacios-Baena, Zaira Raquel, Souli, Maria, Bonomo, Robert A, Carmeli, Yehuda, Paterson, David L, Pascual, Alvaro, Rodriguez-Bano, Jesus, Galvez, J, Falcone, M et al.
DOI: 10.1093/cid/cix606

Dual therapy with darunavir and ritonavir plus lamivudine versus triple therapy with darunavir and ritonavir plus tenofovir disoproxil fumarate and emtricitabine or abacavir and lamivudine for maintenance of HIV-1 viral suppression: randomised, open label, non-inferiority DUAL-GESIDA 8014-RIS-EST45 trial.

PMID: 29020293
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2017
Reference: Clin Infect Dis. 2017 Nov 29;65(12):2112-2118. doi: 10.1093/cid/cix734.
Impact factor: 8.216
Publication type: Paper in international publication
Authors: Pulido, Federico, Ribera, Esteban, Lagarde, Maria, Perez-Valero, Ignacio, Palacios, Rosario, Iribarren, Jose A, Payeras, Antoni, Domingo, Pere, Sanz, Jose, Cervero, Miguel et al.
DOI: 10.1093/cid/cix734

Risk factors that influence the empirical treatment of patients with acute pyelonephritis: a cohort study.

PMID: 28971876
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2017
Reference: Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: AAC.01317-17. doi: 10.1128/AAC.01317-17. Print 2017 Dec.
Impact factor: 4.302
Publication type: Paper in international publication
Authors: Bosch-Nicolau, Pau, Falco, Vicenc, Vinado, Belen, Andreu, Antonia, Len, Oscar, Almirante, Benito, Pigrau, Carles et al.
DOI: 10.1128/AAC.01317-17

[Candidemia and invasive candidiasis approach in critically ill patients: role of the echinocandins].

PMID: 28945064
Journal: Revista Espanola de Quimioterapia
Year: 2017
Reference: Rev Esp Quimioter. 2017 Oct;30(5):355-367. Epub 2017 Sep 25.
Impact factor: 0.75
Publication type: Review in national publication
Authors: Almirante, B, Garnacho-Montero, J, Maseda, E, Candel, F J, Grau, S, Guinea, J, Moreno, I, Munoz, P, Ruiz-Santana, S et al.
DOI:

[Update Chagas disease].

PMID: 26827133
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2016
Reference: Enferm Infecc Microbiol Clin. 2016 Feb;34(2):132-8. doi: 10.1016/j.eimc.2015.12.008. Epub 2016 Jan 28.
Impact factor: 1.53
Publication type: Paper in national publication
Authors: Molina, Israel, Salvador, Fernando, Sanchez-Montalva, Adrian et al.
DOI: 10.1016/j.eimc.2015.12.008

Medical care for refugees: A question of ethics and public health.

PMID: 26811213
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2016
Reference: Enferm Infecc Microbiol Clin. 2016 Feb;34(2):79-82. doi: 10.1016/j.eimc.2015.12.007. Epub 2016 Jan 19.
Impact factor: 1.53
Publication type: Paper in international publication
Authors: Perez-Molina, Jose Antonio, Alvarez-Martinez, Miriam J, Molina, Israel et al.
DOI: 10.1016/j.eimc.2015.12.007

Clinical characteristics, treatment and outcomes of MRSA bacteraemia in the elderly.

PMID: 26723914
Journal: JOURNAL OF INFECTION
Year: 2016
Reference: J Infect. 2016 Mar;72(3):309-16. doi: 10.1016/j.jinf.2015.12.009. Epub 2015 Dec 24.
Impact factor: 4.382
Publication type: Paper in international publication
Authors: Almirante, B, Padilla, Belen, Pintado, Vicente, Almirante, Benito, Lepe, Jose A, Lopez-Medrano, Francisco, Ruiz de Gopegui, Enrique, Martinez, Jose A, Montejo, Jose Miguel, Perez-Nadales, Elena et al.
DOI: 10.1016/j.jinf.2015.12.009

High Resolution Esophageal Manometry in Patients with Chagas Disease: A Cross-Sectional Evaluation.

PMID: 26848957
Journal: PLoS Neglected Tropical Diseases
Year: 2016
Reference: PLoS Negl Trop Dis. 2016 Feb 5;10(2):e0004416. doi: 10.1371/journal.pntd.0004416. eCollection 2016 Feb.
Impact factor: 3.948
Publication type: Paper in international publication
Authors: Moris, Maria, Sanchez-Montalva, Adrian, Accarino, Anna, Ramirez, Kathleen, Azpiroz, Fernando, Ruiz-de-Leon, Antonio, Molina, Israel, Salvador, Fernando, Mego, Marianela et al.
DOI: 10.1371/journal.pntd.0004416

Influenza vaccination during the first six months after Solid Organ transplantation is Efficacious and safe.

PMID: 26232537
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2015
Reference: Clin Microbiol Infect. 2015 Nov;21(11):1040.e11-8. doi: 10.1016/j.cmi.2015.07.014. Epub 2015 Jul 29.
Impact factor: 5.768
Publication type: Paper in international publication
Authors: Perez-Romero, P, Bulnes-Ramos, A, Torre-Cisneros, J, Gavalda, J, Aydillo, T A, Moreno, A, Montejo, M, Farinas, M C, Carratala, J, Munoz, P et al.
DOI: 10.1016/j.cmi.2015.07.014

Risk of progression to high-grade anal intraepithelial neoplasia in HIV-infected MSM.

PMID: 25849833
Journal: AIDS
Year: 2015
Reference: AIDS. 2015 Mar 27;29(6):695-702. doi: 10.1097/QAD.0000000000000603.
Impact factor: 5.554
Publication type: Paper in international publication
Authors: Navarro, Jordi, Landolfi, Stefania, Villar, Judith, Crespo, Manel, Ribera, Esteve, Falco, Vicenc, Guelar, Ana, Tallada, Natalia, Burgos, Joaquin, Curran, Adria et al.
DOI: 10.1097/QAD.0000000000000603

Lymphogranuloma venereum in Barcelona, 2007-2012: the role of seroadaptation in men who have sex with men.

PMID: 24642056
Journal: EPIDEMIOLOGY AND INFECTION
Year: 2015
Reference: Epidemiol Infect. 2015 Jan;143(1):184-8. doi: 10.1017/S0950268814000545. Epub 2014 Mar 18.
Impact factor: 2.535
Publication type: Paper in international publication
Authors: Reyes-Uruena, J M, Garcia De Olalla, P, Vall-Mayans, M, Arando, M, Caballero, E, Cayla, J A, Marti-Pastor, Marc, Armengol, Pere, Jesus Barbera, M, Vives, Alvaro et al.
DOI: 10.1017/S0950268814000545

Disassembling bacterial extracellular matrix with DNase-coated nanoparticles to enhance antibiotic delivery in biofilm infections.

PMID: 25913364
Journal: JOURNAL OF CONTROLLED RELEASE
Year: 2015
Reference: J Control Release. 2015 Jul 10;209:150-8. doi: 10.1016/j.jconrel.2015.04.028. Epub 2015 Apr 23.
Impact factor: 7.705
Publication type: Paper in international publication
Authors: Levato, Riccardo, Julian, Esther, Crespo, Anna, Astola, Jose, Gavalda, Joan, Engel, Elisabeth, Mateos-Timoneda, Miguel Angel, Torrents, Eduard, Baelo, Aida et al.
DOI: 10.1016/j.jconrel.2015.04.028

Daptomycin is effective as antibiotic-lock therapy in a model of Staphylococcus aureus catheter-related infection.

PMID: 24412247
Journal: J INFECTION
Year: 2014
Reference: J Infect. 2014 Jun;68(6):548-52. doi: 10.1016/j.jinf.2014.01.001. Epub 2014 Jan 8.
Impact factor: 4.017
Publication type: Paper in international publication
Authors: Meije, Yolanda, Almirante, Benito, Del Pozo, Jose Luis, Martin, Maria Teresa, Fernandez-Hidalgo, Nuria, Shan, Adriana, Basas, Jana, Pahissa, Albert, Gavalda, Joan et al.
DOI: 10.1016/j.jinf.2014.01.001

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