About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 35131032 Journal: eLife Year: 2022 Reference: Elife. 2022 Feb 8;11. pii: 73926. doi: 10.7554/eLife.73926. Impact factor: 8.146 Publication type: Paper in international publication Authors: Lobo-Jarne, Teresa; Garrido, Marta; Iglesias, Mar; Espinosa, Lluis; Malhotra, Vivek; Alonso-Maranon, Josune; Cantero-Recasens, Gerard et al. DOI: 10.7554/eLife.73926
PMID: 35137195 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Feb 7. pii: 6523371. doi: 10.1093/ndt/gfac029. Impact factor: 5.992 Publication type: Paper in international publication Authors: Decramer, Stephane; Devuyst, Olivier; van Dyck, Maria; Ferraro, Pietro Manuel; Fila, Marc; Francisco, Telma; Ghiggeri, Gian Marco; Gondra, Leire; Guarino, Stefano; Hooman, Nakysa et al. DOI: 10.1093/ndt/gfac029
PMID: 33779754 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Jun 23;37(7):1270-1280. doi: 10.1093/ndt/gfab075. Impact factor: 5.992 Publication type: Paper in international publication Authors: Marco, Helena; Caravaca-Fontan, Fernando; Diaz-Encarnacion, Montserrat; Cabello, Virginia; Ariceta, Gema; Quintana, Luis F; Barros, Xoana; Rodriguez-Mendiola, Nuria; Mon, Carmen; Fraga, Gloria et al. DOI: 10.1093/ndt/gfab075
PMID: 34971403 Journal: PEDIATRIC NEPHROLOGY Year: 2022 Reference: Pediatr Nephrol. 2022 Aug;37(8):1867-1875. doi: 10.1007/s00467-021-05226-1. Epub 2021 Dec 31. Impact factor: 3.714 Publication type: Paper in international publication Authors: Jobs, K; Yazicioglu, Burcu; Bakkaloglu, Sevcan A; Abranches, M; Akman, S; Alpay, H; Ariceta, G; Atmis, B; Bael, A; Bakkaloglu, S A et al. DOI: 10.1007/s00467-021-05226-1
PMID: 33841866 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2021 Mar 30;14(4):1207-1215. doi: 10.1093/ckj/sfaa247. eCollection 2021 Apr. Impact factor: 4.452 Publication type: Paper in international publication Authors: Jatem, Elias, Madrid, Alvaro, Lopez, Mercedes, Segarra, Alfons, Martinez, Cristina, Roca, Neus et al. DOI: 10.1093/ckj/sfaa247
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
