About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 35021312 Journal: World Journal of Mens Health Year: 2022 Reference: World J Mens Health. 2022 Apr;40(2):270-279. doi: 10.5534/wjmh.210117. Epub 2021 Dec 27. Impact factor: Publication type: Paper in international publication Authors: Campistol, Miriam; Celma, Anna; de Torres, Ines; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Santamaria, Anna; Semidey, Maria E et al. DOI: 10.5534/wjmh.210117
PMID: 33532864 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Mar 25;37(4):687-696. doi: 10.1093/ndt/gfab019. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Ars, Elisabet; Bujons-Tur, Anna; Bullich, Gemma; Domingo-Gallego, Andrea; Ejarque-Vila, Laia; Fraga, Gloria; Furlano, Monica; Llano-Rivas, Isabel; Lluis, Guirado et al. DOI: 10.1093/ndt/gfab019
PMID: 35326740 Journal: Cancers Year: 2022 Reference: Cancers (Basel). 2022 Mar 21;14(6). pii: cancers14061589. doi: 10.3390/cancers14061589. Impact factor: Publication type: Paper in international publication Authors: Abascal, Jose M; Borque-Fernando, Angel; Celma, Anna; de Torres, Ines M; Escobar, Manel; Esteban, Luis M; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas et al. DOI: 10.3390/cancers14061589
PMID: 35243388 Journal: European Urology Open Science Year: 2022 Reference: Eur Urol Open Sci. 2022 Jan 23;37:38-44. doi: 10.1016/j.euros.2021.12.009. eCollection 2022 Mar. Impact factor: Publication type: Paper in international publication Authors: Campistol, Miriam; Celma, Anna; de Torres, Ines; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Santamaria, Anna; Semidey, Maria E; Trilla, Enrique et al. DOI: 10.1016/j.euros.2021.12.009
PMID: 33841866 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2021 Mar 30;14(4):1207-1215. doi: 10.1093/ckj/sfaa247. eCollection 2021 Apr. Impact factor: Publication type: Paper in international publication Authors: Jatem, Elias; Lopez, Mercedes; Madrid, Alvaro; Martinez, Cristina; Roca, Neus; Segarra, Alfons et al. DOI: 10.1093/ckj/sfaa247
PMID: 33794951 Journal: Orphanet Journal of Rare Diseases Year: 2021 Reference: Orphanet J Rare Dis. 2021 Apr 1;16(1):154. doi: 10.1186/s13023-021-01786-5. Impact factor: Publication type: Letter or abstract Authors: Anton-Gamero, Montserrat; Ariceta, Gema; Chocron, Sara; de la Cerda-Ojeda, Francisco; de Lucas-Collantes, Carmen; Espinosa, Laura; Fernandez-Escribano, Angustias; Fernandez-Fernandez, Marta; Fernandez-Maseda, M masculine Angeles; Ferrando, Susana et al. DOI: 10.1186/s13023-021-01786-5
PMID: 33772065 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 Mar 26;11(1):6957. doi: 10.1038/s41598-021-86218-x. Impact factor: Publication type: Paper in international publication Authors: Arevalo, Jazmine; Lorente, David; Meseguer, Anna; Morote, Juan; Salcedo, Maria Teresa; Trilla, Enrique et al. DOI: 10.1038/s41598-021-86218-x
PMID: 33245331 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Feb 20;36(3):413-425. doi: 10.1093/ndt/gfaa210. Impact factor: Publication type: Paper in international publication Authors: Allinovi, M; Allinovi, M; Alpay, H; Ariceta, G; Askiti, V; Aufricht, C; Bacchetta, J; Bacchetta, Justine; Bakkaloglu, S A; Bakkaloglu, S A et al. DOI: 10.1093/ndt/gfaa210
PMID: 31910234 Journal: PLoS One Year: 2020 Reference: PLoS One. 2020 Jan 7;15(1):e0227340. doi: 10.1371/journal.pone.0227340. eCollection 2020. Impact factor: Publication type: Paper in international publication Authors: Alcaraz, Estefania; Bayascas, Jose R; Borgo, Christian; Itarte, Emilio; Marin, Oriano; Meseguer, Anna; Pinna, Lorenzo A; Plana, Maria; Ruzzene, Maria; Salvi, Mauro et al. DOI: 10.1371/journal.pone.0227340
PMID: 30946218 Journal: TRANSPLANTATION Year: 2020 Reference: Transplantation. 2020 Jan;104(1):137-144. doi: 10.1097/TP.0000000000002726. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Baiko, Sergey; Battelino, Nina; Bjerre, Anna; Bonthuis, Marjolein; Cransberg, Karlien; Dyck, Maria Van; Groothoff, Jaap W; Harambat, Jerome; Jager, Kitty J et al. DOI: 10.1097/TP.0000000000002726
PMID: 32279925 Journal: HUMAN IMMUNOLOGY Year: 2020 Reference: Hum Immunol. 2020 Jun;81(6):293-299. doi: 10.1016/j.humimm.2020.03.003. Epub 2020 Apr 9. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Burballa, Carla; Crespo, Marta; Garcia, Carme; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores; Reed, Elaine F; Valenzuela, Nicole M et al. DOI: 10.1016/j.humimm.2020.03.003
PMID: 33133750 Journal: Journal of pediatric intensive care Year: 2020 Reference: J Pediatr Intensive Care. 2020 Dec;9(4):304-306. doi: 10.1055/s-0040-1709655. Epub 2020 Apr 17. Impact factor: 0 Publication type: Letter or abstract Authors: Esmel-Vilomara, Roger, Cruz, Alejandro, Inoriza, Cristina, Andreu, Eva, Munar, Francisca et al. DOI: 10.1055/s-0040-1709655
PMID: 30411406 Journal: TRANSPLANT INTERNATIONAL Year: 2019 Reference: Transpl Int. 2019 Mar;32(3):313-322. doi: 10.1111/tri.13372. Epub 2018 Nov 28. Impact factor: Publication type: Paper in international publication Authors: Angel, Alonso; Beneyto, Isabel; Cantarell, Carmen; Crespo, Marta; Fernandez, Ana; Franco, Antonio; Gonzalez Roncero, Francisco; Guirado, Lluis; Hernandez, Domingo; Jacobs-Cacha, Conxita et al. DOI: 10.1111/tri.13372
PMID: 30707220 Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Year: 2019 Reference: Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):473-487. doi: 10.1167/iovs.18-25000. Impact factor: Publication type: Paper in international publication Authors: Bonet, Aina; Carretero, Ana; Casellas, Alba; Catita, Joana; Lopez-Luppo, Mariana; Mendes-Jorge, Luisa; Mendez-Ferrer, Simon; Meseguer, Anna; Nacher, Victor; Navarro, Marc et al. DOI: 10.1167/iovs.18-25000
PMID: 30693384 Journal: PEDIATRIC NEPHROLOGY Year: 2019 Reference: Pediatr Nephrol. 2019 May;34(5):943-949. doi: 10.1007/s00467-019-4192-7. Epub 2019 Jan 28. Impact factor: Publication type: Editorail in international publication Authors: Ariceta, Gema et al. DOI: 10.1007/s00467-019-4192-7
PMID: 30506144 Journal: PEDIATRIC NEPHROLOGY Year: 2019 Reference: Pediatr Nephrol. 2019 Mar;34(3):475-486. doi: 10.1007/s00467-018-4116-y. Epub 2018 Nov 30. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Dehmel, Bastian; Hidalgo, Guillermo; Iles, Janet N; Jiang, Xun; Laskin, Benjamin; Schaefer, Franz; Shahinfar, Shahnaz; Vande Walle, Johan; Warady, Bradley A et al. DOI: 10.1007/s00467-018-4116-y
PMID: 29773235 Journal: Year: 2018 Reference: Nefrologia (Engl Ed). 2018 Sep-Oct;38(5):528-534. doi: 10.1016/j.nefro.2018.02.008. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Burballa, Carla; Cecchini, Lluis; Crespo, Marta; Frances, Albert; Fumado, Lluis; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores et al. DOI: 10.1016/j.nefro.2018.02.008
PMID: 29884503 Journal: Year: 2018 Reference: Nefrologia (Engl Ed). 2018 Sep-Oct;38(5):503-513. doi: 10.1016/j.nefro.2018.03.003. Epub 2018 Jun 5. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Bermejo, Sheila; Burballa, Carla; Buron, Andrea; Buxeda, Anna; Crespo, Marta; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores et al. DOI: 10.1016/j.nefro.2018.03.003
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
