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Liver Diseases

The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.

Team

Joan Genescà Ferrer

Joan Genescà Ferrer

Head of group
Liver Diseases
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Josep Quer Sivila

Josep Quer Sivila

Main researcher
Liver Diseases
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Maria Martell Pérez-Alcalde

Maria Martell Pérez-Alcalde

Main researcher
Liver Diseases
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Carolina Campos Martinez

Carolina Campos Martinez

Predoctoral researcher
Liver Diseases
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Jordi Llaneras Artigues

Jordi Llaneras Artigues

Predoctoral researcher
Liver Diseases
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Nerea Gómez Mateos

Nerea Gómez Mateos

Liver Diseases
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Joan Genescà Ferrer

Joan Genescà Ferrer

Head of group
Liver Diseases
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Josep Quer Sivila

Josep Quer Sivila

Main researcher
Liver Diseases
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Maria Martell Pérez-Alcalde

Maria Martell Pérez-Alcalde

Main researcher
Liver Diseases
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Carolina Campos Martinez

Carolina Campos Martinez

Predoctoral researcher
Liver Diseases
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Jordi Llaneras Artigues

Jordi Llaneras Artigues

Predoctoral researcher
Liver Diseases
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Nerea Gómez Mateos

Nerea Gómez Mateos

Liver Diseases
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Research lines

Càncer hepàtic

Biòpsia liquida en carcinoma hepatocel·lular

Biomarcadors de carcinoma hepatocel·lular

Efectes de la suplementació del Zinc en models preclínics de carcinoma hepatocel·lular

Assaigs clínics per carcinoma hepatocel·lular

IP: Beatriz Minguez Rosique

Cirrosis i malalties vasculars hepàtiques

Trombosis portal

Malalties vasculars porto-sinusoïdals

Hipertensió portal

Encefalopatia hepàtica

IP: Macarena Simon-Talero Horga

Hepatitis virals - biologia molecular

Subtipat i resistències del virus de la hepatitis C

Quasispècies del virus de la hepatitis E

Exosomes hepàtics en malalties hepàtiques i tumors hepàtics

Identificació, caracterització i variabilitat d’agents virals per seqüenciació massiva, Next Generation Sequencing (NGS)


Serveis o tecnologies rellevants


Seqüenciació Sanger i massiva (NGS)

Extracció i amplificació àcids nucleics

Filogènia molecular disseny primers

Tècniques de Biologia Molecular

Gradients per aïllament i estudi d'exosomes en plasma i femta

Citometria de Flux

Resposta immune cel·lular

Cultius

Clonació, expressió de proteïnes recombinants en cultius cel·lulars

Bioinformàtica

IP: Juan Ignacio Esteban Mur, Josep Quer Sivila

Hepatitis virals i immunitat

Resposta immune en pacients amb hepatitis crònica B (HBeAg negatius)

Marcadors serològics i virològics per monitoritzar la infecció crònica per VHB i VHD

Mecanismes d'interacció entre VHB i VHD

Estudis fenotípics in vitro en models de transfecció o infecció del VHB i VHD

Virus de la hepatitis E

Eliminació del virus de la hepatitis C en poblacions d' alta prevalença

Mecanismes fisiopatològics de la hepatitis autoimmune

Hepatitis immunomediadas per inhibidors de checkpoint oncològics


Serveis o tecnologies rellevants:


Estudi de les quasispècies dels virus VHB i VHD per seqüenciació massiva

IP: Maria Buti Ferret, Maria del Mar Riveiro Barciela

Projects

Non-invasive assessment of cACLD and CSPH

IP: Joan Genescà Ferrer
Collaborators: Juan Bañares Sanchez
Funding agency: Hospital Universitari Vall d'Hebron
Funding: 35000
Reference: AULA/2024/BAÑERAS
Duration: 01/06/2024 - 31/05/2025

Plataforma de soporte para la Investigación Clínica

IP: Inmaculada Fuentes Camps
Collaborators: Antonio Moreno Galdó, Rafael Simó Canonge, Tamara Del Rio Higueras, Ariadna Martín Balcells, Mª Eulàlia Molinas Guilera, Laura Cascales Bolaño, Olga Sánchez- Maroto Carrizo, Maria Soraya Badia Ventura, Angelica Valderrama Rodríguez, Amaia Latasa Arrazubi, Joan Genescà Ferrer, Gemma Vona Giralt, Paula Isabel Roldan Caballero
Funding agency: Instituto de Salud Carlos III
Funding: 274920
Reference: PT23/00062
Duration: 01/01/2024 - 31/12/2026

ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients

IP: José Raul Herance Camacho
Collaborators: Beatriz Minguez Rosique, Clara Ramírez Serra, Cristina Gamez Cenzano, Juan Manuel Pericàs Pulido, Nuria Roson Gradaille, Andreea Ciudin Mihai, Alberto Roque Pérez, Queralt Martin Saladich, Maria Nazarena Pizzi, Ramón Vilallonga Puy
Funding agency: EUROPEAN COMMISSION
Funding: 724000
Reference: ARTEMIS_HE-HLTH2023
Duration: 01/01/2024 - 31/12/2027

Application of bioinformatic tools in the diagnosis of infectious diseases through metagenomics and deep-sequencing

IP: Josep Quer Sivila
Collaborators: Marta Ibañez Lligoña, Miriam Izquierdo Sans
Funding agency: Fundació "La Caixa"
Funding: 117900
Reference: 132074
Duration: 01/09/2023 - 31/08/2026

Publications

Integrating viral hepatitis management into the emergency department: A further step towards viral hepatitis elimination.

PMID: 38074506
Journal: JHEP Reports
Year: 2024
Reference: JHEP Rep. 2023 Oct 12;6(1):100932. doi: 10.1016/j.jhepr.2023.100932. eCollection 2024 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Banares, Juan; Barreira-Diaz, Ana; Blanco-Grau, Albert; Buti, Maria; Campins, Magda; Casado, Miguel Angel; Colom, Joan; Dominguez-Hernandez, Raquel; Esteban, Rafael; Falco-Roget, Anna et al.
DOI: 10.1016/j.jhepr.2023.100932

Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL.

PMID: 38226342
Journal: EClinicalMedicine
Year: 2024
Reference: EClinicalMedicine. 2023 Dec 26;67:102384. doi: 10.1016/j.eclinm.2023.102384. eCollection 2024 Jan.
Impact factor:
Publication type: Paper in international publication
Authors: Genesca, Joan; Koenig, Franz; Machin, Nuria; Millar, Daniel; Pericas, Juan M; Posch, Martin; Rodriguez-Navarro, Sarai; Spiertz, Cecile; Van Dessel, Ann et al.
DOI: 10.1016/j.eclinm.2023.102384

Risk factors associated with mortality among elderly patients with COVID-19: Data from 55 intensive care units in Spain.

PMID: 36906462
Journal: Pulmonology
Year: 2023
Reference: Pulmonology. 2023 Sep-Oct;29(5):362-374. doi: 10.1016/j.pulmoe.2023.01.007. Epub 2023 Feb 17.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, F; Castaneda, T G; Cilloniz, C; de Gonzalo-Calvo, D; Fernandez-Barat, L; Ferrer, R; Gabarrus, A; Garcia-Gasulla, D; Motos, A; Penuelas, O et al.
DOI: 10.1016/j.pulmoe.2023.01.007

Review article: The need for more efficient and patient-oriented drug development pathways in NASH-setting the scene for platform trials.

PMID: 36918740
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2023
Reference: Aliment Pharmacol Ther. 2023 May;57(9):948-961. doi: 10.1111/apt.17456. Epub 2023 Mar 14.
Impact factor:
Publication type: Review in international publication
Authors: Aaes-Jorgensen, Anders; Anstee, Quentin M; Anstee, Quentin M; Balthaus, Tania; Capuano, George; de Preville, Natalie; Di Prospero, Nicholas A; DiProspero, Nicholas A; Duca, Anna; Genesca, Joan et al.
DOI: 10.1111/apt.17456

Uncovering the NAFLD burden in people living with HIV from high- and middle-income nations: a meta-analysis with a data gap from Subsaharan Africa.

PMID: 36924219
Journal: Journal of the International AIDS Society
Year: 2023
Reference: J Int AIDS Soc. 2023 Mar;26(3):e26072. doi: 10.1002/jia2.26072.
Impact factor:
Publication type: Review in international publication
Authors: Banares, Juan; Curran, Adria; Lazarus, Jeffrey V; Manzano-Nunez, Ramiro; Navarro, Jordi; Pericas, Juan M; Rivera-Esteban, Jesus; Schattenberg, Jorn M; Sena, Elena et al.
DOI: 10.1002/jia2.26072

Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period.

PMID: 36987799
Journal: Experimental and Clinical Transplantation
Year: 2023
Reference: Exp Clin Transplant. 2023 Mar;21(3):236-244. doi: 10.6002/ect.2022.0412.
Impact factor:
Publication type: Paper in international publication
Authors: Castells, Lluis; Dopazo, Cristina; Len, Oscar; Llado, Laura; Los-Arcos, Ibai; Lung, Mayli; Nuvials, Xavier; Oriol, Isabel; Perez-Cameo, Cristina; Sabe, Nuria et al.
DOI: 10.6002/ect.2022.0412

Monitoring progress towards elimination of hepatitis B and C in the EU/EEA.

PMID: 36962761
Journal: PLOS global public health
Year: 2022
Reference: PLOS Glob Public Health. 2022 Aug 17;2(8):e0000841. doi: 10.1371/journal.pgph.0000841. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Axelsson, Maria; Buti, Maria; Diaz, Asuncion; Duffell, Erika; Fursa, Olga; Hendrickx, Greet; James, Cary; Klavs, Irena; Korenjak, Marko; Maticic, Mojca et al.
DOI: 10.1371/journal.pgph.0000841

Radiography-based triage for COVID-19 in the Emergency Department in a Spanish cohort of patients.

PMID: 35702721
Journal: Medicina clinica (English ed.)
Year: 2022
Reference: Med Clin (Engl Ed). 2022 May 27;158(10):466-471. doi: 10.1016/j.medcle.2021.05.021. Epub 2022 Jun 9.
Impact factor:
Publication type: Paper in international publication
Authors: Arranz-Betegon, Maria; Canas-Ruano, Esperanza; Domingo-Baldrich, Eva; Fernandez-Codina, Andreu; Garcia-Vives, Eloi; Gil-Vila, Albert; Llaneras-Artigues, Jordi; Meza, Beatriz; Michelena, Xabier; Orozco-Galvez, Olimpia et al.
DOI: 10.1016/j.medcle.2021.05.021

Population screening for liver fibrosis: towards early diagnosis and intervention for chronic liver diseases.

PMID: 34537988
Journal: HEPATOLOGY
Year: 2022
Reference: Hepatology. 2022 Jan;75(1):219-228. doi: 10.1002/hep.32163. Epub 2021 Dec 10.
Impact factor: 17.425
Publication type: Review in international publication
Authors: Hartmann, Phillipp; Gines, Pere; Castera, Laurent; Lammert, Frank; Graupera, Isabel; Serra-Burriel, Miquel; Allen, Alina M; Wong, Vincent Wai-Sun; de Knegt, Robert J; Grgurevic, Ivica et al.
DOI: 10.1002/hep.32163

Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection.

PMID: 34950863
Journal: JHEP reports : innovation in hepatology
Year: 2022
Reference: JHEP Rep. 2021 Oct 24;4(1):100388. doi: 10.1016/j.jhepr.2021.100388. eCollection 2022 Jan.
Impact factor: 0
Publication type: Paper in international publication
Authors: Fletcher, Simon P; van Buuren, Nicholas; Ramirez, Ricardo; Turner, Scott; Chen, Diana; Suri, Vithika; Aggarwal, Abhishek; Moon, Christina; Kim, Sam; Kornyeyev, Dmytro et al.
DOI: 10.1016/j.jhepr.2021.100388

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

PMID: 33758887
Journal:
Year: 2021
Reference: medRxiv. 2021 Mar 12:2021.03.07.21252875. doi: 10.1101/2021.03.07.21252875. Preprint.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Alarcon-Riquelme, Marta E; Amitano, Sara; Asselta, Rosanna; Banales, Jesus; Bernardo, David; Bouysran, Youssef; Bujanda, Luis; Buti, Maria; Butler-Laporte, Guillaume; Cordioli, Mattia et al.
DOI: 10.1101/2021.03.07.21252875

Pilot Trial of Extended Hypothermic Lung Preservation to Analyze Ischemia-reperfusion Injury in Pigs.

PMID: 35698954
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Jul;57(7):479-489. doi: 10.1016/j.arbr.2021.03.015.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Ojanguren, Amaia, Santamaria, Maite, Milla-Collado, Lucia, Fraile, Carlos, Gatius-Caldero, Sonia, Puy, Sara, Boldo, Alba, Gomez-Olles, Susana, Boada-Perez, Meritxell, Esquinas, Cristina et al.
DOI: 10.1016/j.arbr.2021.03.015

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

PMID: 34597274
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2021
Reference: J Clin Invest. 2021 Dec 1;131(23). pii: 152386. doi: 10.1172/JCI152386.
Impact factor: 14.808
Publication type: Paper in international publication
Authors: O'Byrne, Sheila M, Nakanishi, Tomoko, Pigazzini, Sara, Degenhardt, Frauke, Cordioli, Mattia, Butler-Laporte, Guillaume, Nafria-Jimenez, Beatriz, Hov, Johannes R, Migeotte, Isabelle, Renieri, Alessandra et al.
DOI: 10.1172/JCI152386

Assessing Liver Fibrosis Using the FIB4 Index in the Community Setting.

PMID: 34943471
Journal: Diagnostics
Year: 2021
Reference: Diagnostics (Basel). 2021 Nov 29;11(12). pii: diagnostics11122236. doi: 10.3390/diagnostics11122236.
Impact factor: 3.706
Publication type: Paper in international publication
Authors: Buti, Maria, Blanco-Grau, Albert, Gabriel-Medina, Pablo, Rodriguez-Algarra, Francisco, Villena, Yolanda, Lopez-Martinez, Rosa, Augustin, Salvador, Pons, Monica, Cruz, Luz-Maria, Rando-Segura, Ariadna et al.
DOI: 10.3390/diagnostics11122236

Pneumococcal superinfection in COVID-19 patients: A series of 5 cases.

PMID: 33521301
Journal:
Year: 2020
Reference: Med Clin (Engl Ed). 2020 Dec 11;155(11):502-505. doi: 10.1016/j.medcle.2020.05.028. Epub 2020 Dec 14.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Cucchiari, David; Gumucio, Roberto; Md, Emmanuel Coloma; Nicolas, David; Pericas, Juan M; Riera, Josep et al.
DOI: 10.1016/j.medcle.2020.05.028

Trends in Diagnosis of Alpha-1 Antitrypsin Deficiency Between 2015 and 2019 in a Reference Laboratory.

PMID: 33116457
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: Int J Chron Obstruct Pulmon Dis. 2020 Oct 7;15:2421-2431. doi: 10.2147/COPD.S269641. eCollection 2020.
Impact factor: 2.772
Publication type: Paper in international publication
Authors: Belmonte, Irene, Nunez, Alexa, Barrecheguren, Miriam, Esquinas, Cristina, Pons, Monica, Lopez-Martinez, Rosa M, Ruiz, Gerard, Blanco-Grau, Albert, Genesca, Joan, Ferrer, Roser et al.
DOI: 10.2147/COPD.S269641

VRK1 Phosphorylates Tip60/KAT5 and Is Required for H4K16 Acetylation in Response to DNA Damage.

PMID: 33076429
Journal: Cancers
Year: 2020
Reference: Cancers (Basel). 2020 Oct 15;12(10). pii: cancers12102986. doi: 10.3390/cancers12102986.
Impact factor: 6.126
Publication type: Paper in international publication
Authors: Garcia-Gonzalez, Raul, Morejon-Garcia, Patricia, Campillo-Marcos, Ignacio, Salzano, Marcella, Lazo, Pedro A et al.
DOI: 10.3390/cancers12102986

Amino acid substitutions associated with treatment failure of hepatitis C virus infection.

PMID: 32999010
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2020
Reference: J Clin Microbiol. 2020 Nov 18;58(12). pii: JCM.01985-20. doi: 10.1128/JCM.01985-20. Print 2020 Nov 18.
Impact factor: 5.897
Publication type: Paper in international publication
Authors: Soria, Maria Eugenia, Garcia-Crespo, Carlos, Martinez-Gonzalez, Brenda, Vazquez-Sirvent, Lucia, Lobo-Vega, Rebeca, de Avila, Ana Isabel, Gallego, Isabel, Chen, Qian, Garcia-Cehic, Damir, Llorens-Revull, Meritxell et al.
DOI: 10.1128/JCM.01985-20

Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH.

PMID: 31882668
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Dec 27;9(1):20183. doi: 10.1038/s41598-019-56366-2.
Impact factor: 4.011
Publication type: Paper in international publication
Authors: Hide, Diana, Fernandez-Iglesias, Anabel, Gil, Mar, Barbera, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genesca, Joan, Martell, Maria, Raurell, Imma, Bravo, Miren et al.
DOI: 10.1038/s41598-019-56366-2

Significant Improvement in Diagnosis of Hepatitis C Virus Infection by One Step Strategy in a Central Laboratory: An Optimal Tool for Hepatitis C Elimination?

PMID: 31694971
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2019
Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01815-19. doi: 10.1128/JCM.01815-19. Print 2019 Dec 23.
Impact factor: 4.959
Publication type: Paper in international publication
Authors: Quer, Josep, Casis-Saez, Ernesto, Rodriguez-Frias, Francisco, Esteban-Mur, Rafael, Buti-Ferret, Maria, Ferrer-Costa, Roser, Lopez-Martinez, Rosa, Arias-Garcia, Andrea, Rodriguez-Algarra, Francisco, Castellote-Belles, Laura et al.
DOI: 10.1128/JCM.01815-19

Viral load measurements in individuals with hepatitis C infection: On the EASL Recommendations on Treatment of Hepatitis C 2018.

PMID: 31666360
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2019
Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01379-19. doi: 10.1128/JCM.01379-19. Print 2019 Dec 23.
Impact factor: 4.959
Publication type: Letter or abstract
Authors: Rando-Segura, Ariadna, Buti, Maria, Quer, Josep, Lopez-Martinez, Rosa, Rodriguez-Frias, Francisco et al.
DOI: 10.1128/JCM.01379-19

Deep-sequencing study of HCV G4a resistance-associated substitutions in Egyptian patients failing DAA treatment.

PMID: 31571936
Journal: Infection and Drug Resistance
Year: 2019
Reference: Infect Drug Resist. 2019 Sep 10;12:2799-2807. doi: 10.2147/IDR.S214735. eCollection 2019.
Impact factor: 3
Publication type: Paper in international publication
Authors: Amer, Fatma, Yousif, Monkez M, Hammad, Noha M, Garcia-Cehic, Damir, Gregori, Josep, Rando-Segura, Ariadna, Nieto-Aponte, Leonardo, Esteban, Juan Ignacio, Rodriguez-Frias, Francisco, Quer, Josep et al.
DOI: 10.2147/IDR.S214735

2018 Annual Report of the European Liver Transplant Registry (ELTR) - 50-year evolution of liver transplantation.

PMID: 30259574
Journal: TRANSPLANT INTERNATIONAL
Year: 2018
Reference: Transpl Int. 2018 Dec;31(12):1293-1317. doi: 10.1111/tri.13358.
Impact factor:
Publication type: Paper in international publication
Authors: Adam, Rene; Andujar, Rafael Lopez; Azoulay, Daniel; Bachellier, Philippe; Bennet, William; Berlakovich, Gabriela; Boudjema, Karim; Cailliez, Valerie; Cherqui, Daniel; Colledan, Michele et al.
DOI: 10.1111/tri.13358

Characterization of Novel Missense Variants of SERPINA1 Gene Causing Alpha-1 Antitrypsin Deficiency.

PMID: 29232161
Journal: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Year: 2018
Reference: Am J Respir Cell Mol Biol. 2018 Jun;58(6):706-716. doi: 10.1165/rcmb.2017-0179OC.
Impact factor: 4.1
Publication type: Paper in international publication
Authors: Belmonte, Irene, Rodriguez-Frias, Francisco, Vilar, Marcal, Saez, Raquel, Iturbe, Igor, Castillo, Silvia, Molina-Molina, Maria, Texido, Anna, Tirado-Conde, Gema, Lopez-Campos, Jose Luis et al.
DOI: 10.1165/rcmb.2017-0179OC

Immune reconstitution inflammatory syndrome in HIV-infected patients with Pneumocystis jirovecii pneumonia.

PMID: 29187293
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2018
Reference: Enferm Infecc Microbiol Clin. 2018 Dec;36(10):621-626. doi: 10.1016/j.eimc.2017.11.002. Epub 2017 Nov 26.
Impact factor: 1.714
Publication type: Paper in national publication
Authors: Roade Tato, Luisa, Burgos Cibrian, Joaquin, Curran Fabregas, Adria, Navarro Mercade, Jordi, Willekens, Rein, Martin Gomez, Maria Teresa, Ribera Pascuet, Esteban, Falco Ferrer, Vicenc et al.
DOI: 10.1016/j.eimc.2017.11.002

Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant.

PMID: 30519058
Journal: Infection and Drug Resistance
Year: 2018
Reference: Infect Drug Resist. 2018 Nov 8;11:2207-2210. doi: 10.2147/IDR.S172226. eCollection 2018.
Impact factor: 3.443
Publication type: Paper in international publication
Authors: Perales, Celia, Chen, Qian, Soria, Maria Eugenia, Gregori, Josep, Garcia-Cehic, Damir, Nieto-Aponte, Leonardo, Castells, Lluis, Imaz, Arkaitz, Llorens-Revull, Meritxell, Domingo, Esteban et al.
DOI: 10.2147/IDR.S172226

The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship-results from an international cross-sectional survey.

PMID: 28775763
Journal: World Journal of Emergency Surgery
Year: 2017
Reference: World J Emerg Surg. 2017 Aug 1;12:34. doi: 10.1186/s13017-017-0145-2. eCollection 2017.
Impact factor:
Publication type: Paper in international publication
Authors: Abbo, Lilian M; Abu-Zidan, Fikri M; Adesunkanmi, Abdulrashid K; Al-Dahir, Sara; Al-Hasan, Majdi N; Alis, Halil; Alves, Carlos; Ansaloni, Luca; Araujo da Silva, Andre R; Augustin, Goran et al.
DOI: 10.1186/s13017-017-0145-2

Deep sequencing in the management of hepatitis virus infections.

PMID: 28040474
Journal: VIRUS RESEARCH
Year: 2017
Reference: Virus Res. 2017 Jul 15;239:115-125. doi: 10.1016/j.virusres.2016.12.020. Epub 2016 Dec 28.
Impact factor: 2.526
Publication type: Review in national publication
Authors: Quer, Josep, Rodriguez-Frias, Francisco, Gregori, Josep, Tabernero, David, Soria, Maria Eugenia, Garcia-Cehic, Damir, Homs, Maria, Bosch, Albert, Pinto, Rosa Maria, Esteban, Juan Ignacio et al.
DOI: 10.1016/j.virusres.2016.12.020

Effectiveness and safety of ombitasvir, paritaprevir, ritonavir +/- dasabuvir +/- ribavirin: An early access programme for Spanish patients with genotype 1/4 chronic hepatitis C virus infection.

PMID: 27976491
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2017
Reference: J Viral Hepat. 2017 Mar;24(3):226-237. doi: 10.1111/jvh.12637. Epub 2016 Dec 15.
Impact factor: 4.179
Publication type: Paper in international publication
Authors: Perello, C, Real, Y, Jorquera, F, Calleja, J L, Rayuela, Federico Saez, Simon, Miguel Angel, Gonzalez, Jose Manuel, Munoz, Eduardo, Gonzalez, Marta, Jimenez, Miguel et al.
DOI: 10.1111/jvh.12637

Assessment of a novel automatic real-time PCR assay on the Cobas4800 analyzer as a screening platform for HCV genotyping in clinical practice: comparison with massive sequencing.

PMID: 27927921
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2017
Reference: J Clin Microbiol. 2017 Feb;55(2):504-509. doi: 10.1128/JCM.01960-16. Epub 2016 Dec 7.
Impact factor: 3.631
Publication type: Paper in international publication
Authors: Nieto-Aponte, Leonardo, Quer, Josep, Ruiz-Ripa, Alicia, Tabernero, David, Gonzalez, Carolina, Gregori, Josep, Vila, Marta, Asensio, Miriam, Garcia-Cehic, Damir, Ruiz, Gerardo et al.
DOI: 10.1128/JCM.01960-16

alpha1 and alpha2-adrenergic agonists on cirrhotic patients with refractory ascites.

PMID: 26284943
Journal: LIVER INTERNATIONAL
Year: 2016
Reference: Liver Int. 2016 Feb;36(2):177-80. doi: 10.1111/liv.12941.
Impact factor: 4.47
Publication type: Editorail in international publication
Authors: Ventura-Cots, Meritxell, Santos, Begona, Genesca, Joan et al.
DOI: 10.1111/liv.12941

New real-time-PCR method to identify single point mutations in hepatitis C virus.

PMID: 27920481
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2016
Reference: World J Gastroenterol. 2016 Nov 21;22(43):9604-9612.
Impact factor: 2.787
Publication type: Paper in international publication
Authors: Chen, Qian, Belmonte, Irene, Buti, Maria, Nieto, Leonardo, Garcia-Cehic, Damir, Gregori, Josep, Perales, Celia, Ordeig, Laura, Soria, Maria Eugenia, Esteban, Rafael et al.
DOI: 10.3748/wjg.v22.i43.9604

Application of a diagnostic algorithm for the rare deficient variant Mmalton of alpha-1-antitrypsin deficiency: a new approach.

PMID: 27877030
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2016
Reference: Int J Chron Obstruct Pulmon Dis. 2016 Oct 11;11:2535-2541. eCollection 2016.
Impact factor: 3.046
Publication type: Paper in international publication
Authors: Rodriguez-Frias, Francisco, Belmonte, Irene, Barrecheguren, Miriam, Lopez-Martinez, Rosa M, Esquinas, Cristina, Rodriguez, Esther, Miravitlles, Marc et al.
DOI: 10.2147/COPD.S115940

Basal values and changes of liver stiffness predict the risk of disease progression in compensated advanced chronic liver disease.

PMID: 27388262
Journal: DIGESTIVE AND LIVER DISEASE
Year: 2016
Reference: Dig Liver Dis. 2016 Oct;48(10):1214-9. doi: 10.1016/j.dld.2016.06.019. Epub 2016 Jun 25.
Impact factor: 2.719
Publication type: Paper in international publication
Authors: Pons, Monica, Simon-Talero, Macarena, Millan, Laura, Ventura-Cots, Meritxell, Santos, Begona, Augustin, Salvador, Genesca, Joan et al.
DOI: 10.1016/j.dld.2016.06.019

[Littoral cell angioma. An uncommon cause of constitutional syndrome].

PMID: 25070519
Journal: MEDICINA CLINICA
Year: 2015
Reference: Med Clin (Barc). 2015 Mar 9;144(5):239. doi: 10.1016/j.medcli.2014.04.019. Epub 2014 Jul 26.
Impact factor: 1.417
Publication type: Letter or abstract
Authors: Santafe Colomina, Manel, Roade Tato, Luisa, Callejas Moraga, Eduardo L, Pinal Fernandez, Iago et al.
DOI: 10.1016/j.medcli.2014.04.019

Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.

PMID: 26395289
Journal: JOURNAL OF GENERAL VIROLOGY
Year: 2015
Reference: J Gen Virol. 2015 Dec;96(12):3493-3498. doi: 10.1099/jgv.0.000289.
Impact factor: 3.183
Publication type: Paper in international publication
Authors: Casillas, Rosario, Perez-Del-Pulgar, Sofia, Gregori, Josep, Rodriguez-Frias, Francisco, Gonzalez, Patricia, Garcia-Cehic, Damir, Ramirez, Santseharay, Forns, Xavier, Quer, Josep, Esteban, Juan I et al.
DOI: 10.1099/jgv.0.000289

Immunogenicity of hepatitis B vaccine in patients with inflammatory bowel disease and the benefits of revaccination.

PMID: 25160690
Journal: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Year: 2015
Reference: J Gastroenterol Hepatol. 2015 Jan;30(1):92-8. doi: 10.1111/jgh.12712.
Impact factor: 3.504
Publication type: Paper in international publication
Authors: Cossio-Gil, Yolima, Martinez-Gomez, Xavier, Campins-Marti, Magda, Rodrigo-Pendas, Jose Angel, Borruel-Sainz, Natalia, Rodriguez-Frias, Francisco, Casellas-Jorda, Francesc et al.
DOI: 10.1111/jgh.12712

Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus.

PMID: 26714168
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 Dec 29;10(12):e0144816. doi: 10.1371/journal.pone.0144816. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Riveiro-Barciela, Mar, Caballero, Andrea, Gregori, Josep, Homs, Maria, Tabernero, David, Gonzalez, Carolina, Quer, Josep, Blasi, Maria, Casillas, Rosario, Nieto, Leonardo et al.
DOI: 10.1371/journal.pone.0144816

Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadrid.

PMID: 25287719
Journal: RESP RES
Year: 2014
Reference: Respir Res. 2014 Oct 7;15:125. doi: 10.1186/s12931-014-0125-y.
Impact factor: 3.382
Publication type: Paper in international publication
Authors: Lara, Beatriz, Martinez, Maria Teresa, Blanco, Ignacio, Hernandez-Moro, Cristina, Velasco, Eladio A, Rodriguez-Frias, Francisco, Perez, Laura, Vazquez, Irene, Alonso, Javier, Posada, Manuel et al.
DOI: 10.1186/s12931-014-0125-y

Groove sign in eosinophilic fasciitis.

PMID: 25043386
Journal: LANCET
Year: 2014
Reference: Lancet. 2014 Nov 15;384(9956):1774. doi: 10.1016/S0140-6736(14)60526-2. Epub 2014 Jul 17.
Impact factor: 39.207
Publication type: Letter or abstract
Authors: Pinal-Fernandez, Iago, Callejas-Moraga, Eduardo Luis, Roade-Tato, Maria Luisa, Simeon-Aznar, Carmen Pilar et al.
DOI: 10.1016/S0140-6736(14)60526-2

HIV-2 and HTLV-1 infections in Spain, a non-endemic region.

PMID: 25180694
Journal: AIDS REV
Year: 2014
Reference: AIDS Rev. 2014 Jul-Sep;16(3):152-9.
Impact factor: 4.023
Publication type: Paper in international publication
Authors: de Mendoza, Carmen, Caballero, Estrella, Aguilera, Antonio, Piron, Maria, Ortiz de Lejarazu, Raul, Rodriguez, Carmen, Cabezas, Teresa, Gonzalez, Rocio, Trevino, Ana, Soriano, Vicente et al.
DOI:

Relevance of a full-length genomic RNA standard and a thermal-shock step for optimal hepatitis delta virus quantification.

PMID: 24989607
Journal: J CLIN MICROBIOL
Year: 2014
Reference: J Clin Microbiol. 2014 Sep;52(9):3334-8. doi: 10.1128/JCM.00940-14. Epub 2014 Jul 2.
Impact factor: 4.232
Publication type: Paper in international publication
Authors: Blasi, Maria, Lutgehetmann, Marc, Buti, Maria, Esteban, Rafael, Dandri, Maura, Rodriguez-Frias, Francisco, Giersch, Katja, Homs, Maria et al.
DOI: 10.1128/JCM.00940-14

Unconventional secretion is a major contributor of cancer cell line secretomes.

PMID: 23268930
Journal: MOLECULAR & CELLULAR PROTEOMICS
Year: 2013
Reference: Mol Cell Proteomics. 2013 May;12(5):1046-60. doi: 10.1074/mcp.M112.021618. Epub 2012 Dec 26.
Impact factor:
Publication type: Paper in international publication
Authors: Baselga, Jose; Gregori, Josep; Mendez, Olga; Salvans, Candida; Villanueva, Josep; Villarreal, Laura et al.
DOI: 10.1074/mcp.M112.021618

Hepatitis E virus: new faces of an old infection.

PMID: 24114815
Journal: Annals of Hepatology
Year: 2013
Reference: Ann Hepatol. 2013 Nov-Dec;12(6):861-70.
Impact factor: 1.671
Publication type: Review in international publication
Authors: Riveiro-Barciela, Mar, Rodriguez-Frias, Francisco, Buti, Maria et al.
DOI:

Quasispecies structure, cornerstone of hepatitis B virus infection: mass sequencing approach.

PMID: 24222943
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2013
Reference: World J Gastroenterol. 2013 Nov 7;19(41):6995-7023. doi: 10.3748/wjg.v19.i41.6995.
Impact factor: 2.547
Publication type: Review in international publication
Authors: Rodriguez-Frias, Francisco, Buti, Maria, Tabernero, David, Homs, Maria et al.
DOI: 10.3748/wjg.v19.i41.6995

Molecular epidemiology and putative origin of hepatitis C virus in random volunteers from Argentina.

PMID: 24124326
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2013
Reference: World J Gastroenterol. 2013 Sep 21;19(35):5813-27. doi: 10.3748/wjg.v19.i35.5813.
Impact factor: 2.547
Publication type: Paper in international publication
Authors: del Pino, Noemi, Oubina, Jose Raul, Rodriguez-Frias, Francisco, Esteban, Juan Ignacio, Buti, Maria, Otero, Teresa, Gregori, Josep, Garcia-Cehic, Damir, Camos, Silvia, Cubero, Maria et al.
DOI: 10.3748/wjg.v19.i35.5813

Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing.

PMID: 23155338
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2012
Reference: World J Gastroenterol. 2012 Nov 14;18(42):6096-105. doi: 10.3748/wjg.v18.i42.6096.
Impact factor: 2.471
Publication type: Paper in international publication
Authors: Tabernero, David, Quer, Josep, Sanchez, Alex, Corral, Noelia, Esteban, Rafael, Rodriguez-Frias, Francisco, Buti, Maria, Homs, Maria et al.
DOI: 10.3748/wjg.v18.i42.6096

IL28B genetic variation and hepatitis C virus-specific CD4(+) T-cell responses in anti-HCV-positive blood donors.

PMID: 23121365
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2012
Reference: J Viral Hepat. 2012 Dec;19(12):867-71. doi: 10.1111/j.1365-2893.2012.01631.x. Epub 2012 Jul 4.
Impact factor: 4.088
Publication type: Paper in international publication
Authors: Bes, M, Sauleda, S, Campos-Varela, I, Rodriguez-Frias, F, Casamitjana, N, Homs, M, Piron, M, Quer, J, Tabernero, D, Guardia, J et al.
DOI: 10.1111/j.1365-2893.2012.01631.x

alpha1-Antitrypsin in Fibromyalgia: Results of a Randomized, Placebo-Controlled, Double-Blind and Crossover Pilot Trial.

PMID: 22190533
Journal: Musculoskeletal care
Year: 2012
Reference: Musculoskeletal Care. 2012 Sep;10(3):178-83. doi: 10.1002/msc.1000. Epub 2011 Dec 22.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , et al.
DOI: 10.1002/msc.1000

Hepatitis B virus in transfusion medicine: still a problem?

PMID: 22305086
Journal: BIOLOGICALS
Year: 2012
Reference: Biologicals. 2012 May;40(3):180-6. doi: 10.1016/j.biologicals.2011.09.014. Epub 2012 Feb 2.
Impact factor: 1.698
Publication type: Review in international publication
Authors: Hatzakis, A, Arslan, O, Ayob, Y, Belkhiri, D, Bianco, L, Bird, A, Bon, E H, Boukef, K, Brojer, E, Crookes, R et al.
DOI: 10.1016/j.biologicals.2011.09.014

Clinical outcome of acute and chronic hepatitis delta over time: a long-term follow-up study.

PMID: 20546496
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2011
Reference: J Viral Hepat. 2011 Jun;18(6):434-42. doi: 10.1111/j.1365-2893.2010.01324.x.
Impact factor: 3.502
Publication type: Paper in international publication
Authors: , , , , , , , , et al.
DOI: 10.1111/j.1365-2893.2010.01324.x

World Health Organization collaborative study to calibrate the 3rd International Standard for Hepatitis C virus RNA nucleic acid amplification technology (NAT)-based assays.

PMID: 21488880
Journal: VOX SANGUINIS
Year: 2011
Reference: Vox Sang. 2011 May;100(4):409-17. doi: 10.1111/j.1423-0410.2010.01434.x. Epub 2010 Dec 13.
Impact factor: 3.292
Publication type: Paper in international publication
Authors: Gesu, Giovanni, Baylis, S A, Heath, A B, Cuypers, Theo, Koppelman, Marco, Defer, Christine, Fanning, Liam, Cruz, Sandra, Tassen, Steve, Taylor, Paul et al.
DOI: 10.1111/j.1423-0410.2010.01434.x

Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome.

PMID: 21742757
Journal: NUCLEIC ACIDS RESEARCH
Year: 2011
Reference: Nucleic Acids Res. 2011 Oct;39(19):8457-71. Epub 2011 Jul 8.
Impact factor: 7.836
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1093/nar/gkr451

Utility of oligoclonal IgG band detection for MS diagnosis in daily clinical practice.

PMID: 21704629
Journal: JOURNAL OF IMMUNOLOGICAL METHODS
Year: 2011
Reference: J Immunol Methods. 2011 Aug 31;371(1-2):170-3. Epub 2011 Jun 17.
Impact factor: 2.34
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.jim.2011.06.009

Infrequent detection of hepatitis E virus RNA in pregnant women with hepatitis E virus antibodies in Spain.

PMID: 20629948
Journal: LIVER INTERNATIONAL
Year: 2010
Reference: Liver Int. 2010 Nov;30(10):1549-51. doi: 10.1111/j.1478-3231.2010.02304.x.
Impact factor: 2.987
Publication type: Letter or abstract
Authors: , , , , , , , , et al.
DOI: 10.1111/j.1478-3231.2010.02304.x

The use of malaria antibody tests in the prevention of transfusion-transmitted malaria.

PMID: 20136789
Journal: VOX SANGUINIS
Year: 2010
Reference: Vox Sang. 2010 Apr;98(3 Pt 2):468-78. Epub 2010 Jan 28.
Impact factor: 2.585
Publication type: Paper in international publication
Authors: Reesink, H W, Panzer, S, Wendel, S, Levi, J E, Ullum, H, Ekblom-Kullberg, S, Seifried, E, Schmidt, M, Shinar, E, Prati, D et al.
DOI: 10.1111/j.1423-0410.2009.01301.x

Inventory management.

PMID: 20432515
Journal: VOX SANGUINIS
Year: 2010
Reference: Vox Sang. 2010 Apr;98(3 Pt 1):e295-363.
Impact factor: 2.585
Publication type: Letter or abstract
Authors: Sarappa, C, Devine, D V, Sher, G D, Reesink, H W, Panzer, S, Hetzel, P A S, Wong, J K, Horvath, M, Leitner, G C, Schennach, H et al.
DOI:

Laboratory testing of individuals with severe alpha1-antitrypsin deficiency in three European centres.

PMID: 20436173
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2010
Reference: Eur Respir J. 2010 May;35(5):960-8.
Impact factor: 5.527
Publication type: Paper in international publication
Authors: Luisetti, M, Bals, R, Rodriguez-Frias, F, Jardi, R, Herr, C, Miravitlles, M, Ferrarotti, I et al.
DOI: 10.1183/09031936.00069709

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.

PMID: 19208682
Journal: GENOME RESEARCH
Year: 2009
Reference: Genome Res. 2009 Mar;19(3):438-51.
Impact factor: 10.176
Publication type: Paper in international publication
Authors: Fernandez, Agustin F, Rosales, Cecilia, Lopez-Nieva, Pilar, Grana, Osvaldo, Ballestar, Esteban, Ropero, Santiago, Espada, Jesus, Melo, Sonia A, Lujambio, Amaia, Fraga, Mario F et al.
DOI: 10.1101/gr.083550.108

Use of the novel INNO-LiPA line probe assay for detection of hepatitis B virus variants that confer resistance to entecavir therapy.

PMID: 19052182
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2009
Reference: J Clin Microbiol. 2009 Feb;47(2):485-8.
Impact factor: 3.945
Publication type: Paper in international publication
Authors: Buti, Maria, Esteban, Rafael, Schaper, Melanie, Jardi, Rosendo, Rodriguez-Frias, Francisco, Tabernero, David, Homs, Maria et al.
DOI: 10.1128/JCM.01678-08

Hepatitis C virus (HCV)-specific T-cell responses among recombinant immunoblot assay-3-indeterminate blood donors: a confirmatory evidence of HCV exposure.

PMID: 19222816
Journal: TRANSFUSION
Year: 2009
Reference: Transfusion. 2009 Jul;49(7):1296-305.
Impact factor: 3.475
Publication type: Paper in international publication
Authors: Guardia, Jaime, Sauleda, Silvia, Puig, Lluis, Cubero, Maria, Quer, Josep, Piron, Maria, Bes, Marta, Esteban, Juan Ignacio, Casamitjana, Natalia et al.
DOI: 10.1111/j.1537-2995.2009.02103.x

Successful use of entecavir for a severe case of reactivation of hepatitis B virus following polychemotherapy containing rituximab.

PMID: 19836097
Journal: JOURNAL OF HEPATOLOGY
Year: 2009
Reference: J Hepatol. 2009 Dec;51(6):1091-6.
Impact factor: 7.056
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1016/j.jhep.2009.07.012

Thesis

Targeted biodegradable nanoparticles of simvastatin as new therapeutic tool for chornic liver disease

PhD student: Mar Gil Soler
Director/s: Maria Nieves Martell Pérez-Alcalde, Diana Hide Alferez
University: Universidad Autònoma de Barcelona
Year: 2023

Experimental models in non-alcoholic steatohepatitis ans effects of therapeutic strantegies based on gut microbiota

PhD student: Aurora Barbera Belles
Director/s: Maria Nieves Martell Pérez-Alcalde, Salvador Augustin Recio
University: Universidad Autònoma de Barcelona
Year: 2023

Studies of viral and host biomarkers in hepatitis C virus infected patients

PhD student: Meritxell Llorens Revull
Director/s: Josep Quer Sivila, Marta Bes Maijo, Celia Belen Perales Viejo
University: Universitat Autònoma de Barcelona
Year: 2023

Liquid biopsy in hepatocellular carcinoma: Utility of circulating cell-free DNA profiling and cytokine levels in hepatocellular carcinoma management

PhD student: Elena Vargas Accarino, Elena Vargas Accarino
Director/s: Beatriz Minguez Rosique, Maria del Mar Riveiro Barciela
University:
Year: 2023

Impact of hepatitis D viraemia on patient liver-related outcomes

PhD student: Adriana Palom Agusti, Adriana Palom Agusti
Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela
University: Universitat Autònoma de Barcelona
Year: 2022

Nuevos horizontes en la epidemiología, clínica, tratamiento y cribado de la infección por el virus de la hepatitis C en la era de los antivirales de acción directa, de Jordi Llaneras Artigues

PhD student: Jordi Llaneras Artigues
Director/s: Maria Buti Ferret, Maria del Mar Riveiro Barciela
University: Universitat Autònoma de Barcelona
Year: 2022

Optimización de factores pronósticos y tratamiento de la hemorragia digestiva por varices esofágicas en pacientes con cirrosis hepática.

PhD student: IRENE CONEJO SOSA
Director/s: Salvador Augustin Recio
University: Universidad Autònoma de Barcelona
Year: 2021

Estudi de caracterització i diagnòstic de la infecció aguda i crònica pel virus de l'Hepatitis E

PhD student: Sofia Romina Piriz Ruzo
Director/s: Josep Quer Sivila, Maria Buti Ferret, Francisco Rodríguez Frias
University: Universidad Autònoma de Barcelona
Year: 2021

Nuevos tratamientos en esteatohepatitis no alcohólica experimental: Combinación de estatinas y antagonistas del receptor A de endotelina para la recuperación del fenotipo alterado de las células del sinusoide hepático

PhD student: Miren Bravo Garmendia
Director/s: Maria Nieves Martell Pérez-Alcalde, Meritxell Genesca Ferrer
University: Universidad Autònoma de Barcelona
Year: 2020

Estudio de la quasiespecies del virus de la hepatitis delta: Análisis de la región del antígeno delta y de la ribozima

PhD student: Sara Sopena Santisteve
Director/s: Maria Buti Ferret, David Tabernero Caellas
University: Universidad Autònoma de Barcelona
Year: 2020

Paper de l'elastografia hepàtica i esplènica en el diagnòstic, segument i tractament de la malaltia hepàtica crònica avançada compensada

PhD student: Mònica Pons Delgado
Director/s: Joan Genescà Ferrer, Salvador Augustin Recio
University: Universidad Autònoma de Barcelona
Year: 2019

Canvis morfofuncionals en un model animal experimental de malaltia hepàtica per fetge gras no alcohòlic després de tractament amb cirurgia bariàtrica versus dieta hipocalòrica

PhD student: Eider Talavera Urquijo, Eider Talavera Urquijo
Director/s: José Maria Balibrea del Castillo, Maria Nieves Martell Pérez-Alcalde, Salvador Augustin Recio
University: Universidad Autònoma de Barcelona
Year: 2018

Caracterización molecular del perfil de resistencias del virus de la hepatitis C después del fallo terapéutico a antivirales de acción directa mediante secuenciación masiva

PhD student: Qian Chen
Director/s: Josep Quer Sivila, Celia Belen Perales Viejo, Josep Gregori Font
University: Universidad Autònoma de Barcelona
Year: 2018

Nuevos modelos experimentales para el estudio de mecanismos fisiopatológicos

PhD student: Teresa García Lezana
Director/s: Salvador Augustin Recio, Laia Chavarria Vilarasau, Joan Genescà Ferrer
University: Universidad Autònoma de Barcelona
Year: 2017

Complejidad de la cuasiespecie del virus de la Hepatitis B en la región X/precore: asociación con la evolución de la infección con y sin tratamiento antiviral

PhD student: Andrea Caballero Garralda
Director/s: Maria Buti Ferret, Francisco Rodríguez Frias
University: Universidad Autònoma de Barcelona
Year: 2016

Estudi de la composició de la quasiespècies del virus de la hepatitis B a les regions codificants de les proteïnes de l'envolta i la polimerasa viral per seqüenciació massiva: associació de les seves variants genètiques amb el tractament antiviral de la hepatitis B crònica amb anàlegs de nucleòsids/nucleòtids

PhD student: David Tabernero Caellas
Director/s: Maria Buti Ferret, Francisco Rodríguez Frias
University: Universidad Autònoma de Barcelona
Year: 2015

Tratamiento de la recurrencia de la infección por VHC en pacientes trasplantados hepáticos. Optimización del proceso.

PhD student: Isabel Campos Varela
Director/s: Juan Ignacio Esteban Mur, Lluis Castells Fusté
University: Universidad Autònoma de Barcelona
Year: 2013

Analysis of the natural evolution of the hepatitis B virus quasispecies in the preCore/Core regions and treatment effects using conventional techniques and ultra-deep pyrosequencing

PhD student: Maria Homs Riba
Director/s: Maria Buti Ferret, Francisco Rodríguez Frias
University: Universidad Autònoma de Barcelona
Year: 2012

Pronóstico de la hemorragia aguda por varices esofágicas en pacientes con cirrosis hepática

PhD student: Salvador Augustin Recio
Director/s: Joan Genescà Ferrer
University: Universidad Autònoma de Barcelona
Year: 2011

Edema cerebral de bajo grado en la encefalopatía hepática

PhD student: Beatriz Minguez Rosique
Director/s:
University: Universidad Autònoma de Barcelona
Year: 2007

Blog

News

Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.

Preliminary study results confirm that the drug resmetirom reduces the presence of fat, inflammation, cell damage and fibrosis in the liver.

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

Job offers

Clinical Researcher Liver Diseases Research Group _20240223
Start date:
01/07/2024
End date:
18/07/2024
Document: Download
Licensed technician_Group of Hepatology_20240219
Start date:
28/06/2024
End date:
12/07/2024
Document: Download
Postdoctoral Researcher_Advanced Chronic Liver Disease Laboratory_20240198
Start date:
11/06/2024
End date:
25/06/2024
Document: Download

Estudi sobre els patrons de consum habitual de l'alcohol en població jove

Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.

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