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Neuroradiology

The main characteristic of our group is its multidisciplinary nature, as it is comprised of neuroradiologists, technologists, and a physicist, engineer, and biochemist.

The main objectives of our projects are to gain knowledge about the pathophysiologic mechanisms implicated in several neurological diseases and to evaluate new biomarkers and therapies through the use of qualitative and quantitative magnetic resonance (MR) and computed tomography (CT) techniques, and by applying artificial intelligence tools to create prognostic models. Our focus is on the study of diseases such as multiple sclerosis, epilepsy, neuro-oncology, and stroke.

In addition, because of the experience we have acquired along the years in performing MR studies, we act as a platform for designing MR-based projects, processing images, and conducting quantitative data analysis.

Team

Sofía María Sceppacuercia

Sofía María Sceppacuercia

Predoctoral researcher
Neuroradiology
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Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
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Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
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Carla Gonzalez Junyent

Carla Gonzalez Junyent

Predoctoral researcher
Neuroradiology
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Cristina Auger Acosta

Cristina Auger Acosta

Research technician
Neuroradiology
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Deborah Pareto Onghena

Deborah Pareto Onghena

Main researcher
Neuroradiology
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Sofía María Sceppacuercia

Sofía María Sceppacuercia

Predoctoral researcher
Neuroradiology
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Ana Maria Nieto Montoya

Ana Maria Nieto Montoya

Administration and Management
Neuroradiology
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Andrea De Barros Figueredo

Andrea De Barros Figueredo

Predoctoral researcher
Neuroradiology
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Carla Gonzalez Junyent

Carla Gonzalez Junyent

Predoctoral researcher
Neuroradiology
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Cristina Auger Acosta

Cristina Auger Acosta

Research technician
Neuroradiology
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Deborah Pareto Onghena

Deborah Pareto Onghena

Main researcher
Neuroradiology
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Research lines

Application of MR techniques in the assessment of psychiatric disorders

The purpose is to investigate the effects of psychiatric disorders on brain structure, integrity and function.

IP: Alex Rovira Cañellas

Application of MR techniques in the study of seizures

The objective of this research line is to evaluate the structural changes that occur in the brain after or during epileptic seizures using different MRI techniques, as well as assess the role of MRI in the etiological diagnosis and location of the epileptogenic focus and analyze its influence on the treatment and evolution of these patients.

IP: Silvana Isabel Sarria Estrada

Application of MRI imaging to the study of Parkinson's disease

The aim of the line is to evaluate the added value of the information provided by MRI techniques, mainly aimed at the evaluation of melanin, myelin, presence of Fe, structural and functional connectivity in the study of Parkinson’s disease.

IP: Fco. Javier Aymerich Martínez, Alex Rovira Cañellas

Application of MRI in autoimmune disorders: NMOSD and MOGAD

The objective of this research line is to evaluate the value of MRI in the diagnosis of autoimmune (NMOSD and MOGAD) diseases and as a marker of progression and treatment response.

IP: Cristina Auger Acosta, Alex Rovira Cañellas

Projects

ResEM Project - Desarrollo de un modelo global de reserva funcional y estructural del sistema nervioso central en esclerosis múltiple

IP: Jaume Sastre Garriga
Collaborators: Cristina Auger Acosta, Carme Santoyo Medina, Manel Alberich Jordà, M Jesus Arevalo Navines, Xavier Montalban Gairín, Lucía Gutiérrez Ruiz, Neus Mongay Ochoa
Funding agency: Instituto de Salud Carlos III
Funding: 157300
Reference: PI22/00750
Duration: 01/01/2023 - 31/12/2025

Caracterización estructural y funcional de la vía visual anterior en pacientes con esclerosis múltiple temprana (VISIONEM).

IP: Angela Vidal Jordana
Collaborators: Dulce María Moncho Rodríguez, Alex Rovira Cañellas, Manel Alberich Jordà, Neus Mongay Ochoa, Joaquin Castillo Justribo, Sergio Cabello
Funding agency: Instituto de Salud Carlos III
Funding: 48400
Reference: PI22/01589
Duration: 01/01/2023 - 31/12/2025

Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL.

IP: Ramón Vilallonga Puy
Collaborators: Mercedes Pérez Lafuente, Nuria Roson Gradaille, Laura Puente Ramo, Carla Gonzalez Junyent, Marta Comas Martínez, Alba Rojano Toimil, Arturo Cirera De Tudela, Elisa Merino Peña, Clara Pañella Vilamú, Ana Maria Ciscar Bellés, Carlos Petrola Chacón
Funding agency: Instituto de Salud Carlos III
Funding: 171820
Reference: PI22/00880
Duration: 01/01/2023 - 31/12/2025

Deciphering clinical features and pathogenesis of myelin oligodendrocyte glycoprotein (MOG) antibodies in adult patients with a first demyelinating syndrome

IP: Alvaro Cobo Calvo
Collaborators: Rosalia Horno Ocaña, Cristina Auger Acosta, Deciphering clinical features and pathogenesis of myelin oligodendrocyte glycoprotein (MOG) antibodies in adult patients with a , Luciana Midaglia Fernandez, Breogan Rodriguez Acevedo, Mireia Castillo Juarez
Funding agency: Instituto de Salud Carlos III
Funding: 134915
Reference: PI20/00800
Duration: 01/01/2021 - 30/06/2025

Publications

Posterior fossa ring-enhancing lesions in the adult immunocompetent host: illustrative cases, systematic review, and proposed diagnostic algorithm.

PMID: 39880690
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2025
Reference: AJNR Am J Neuroradiol. 2025 Jan 29:ajnr.A8677. doi: 10.3174/ajnr.A8677.
Impact factor:
Publication type: Paper in international publication
Authors: Bocchio, Anna Paola; Borrelli, Serena; de Hennin, Alexia; El Sankari, Souraya; Finet, Patrice; Lolli, Valentina; Maggi, Pietro; Reich, Daniel S; Rovira, Alex; Scoppettuolo, Pasquale et al.
DOI: 10.3174/ajnr.A8677

Age-Related Disability Outcomes After a First Demyelinating Event.

PMID: 39903901
Journal: NEUROLOGY
Year: 2025
Reference: Neurology. 2025 Feb 25;104(4):e210305. doi: 10.1212/WNL.0000000000210305. Epub 2025 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo Navines, Maria Jesus; Arino, Helena; Arrambide, Georgina; Auger, Cristina; Bollo, Luca; Carbonell-Mirabent, Pere; Carvajal, Rene; Castillo, Joaquin; Cobo-Calvo, Alvaro; Comabella, Manuel et al.
DOI: 10.1212/WNL.0000000000210305

Uncovering alternative diagnoses in patients with clinical syndromes suggestive of multiple sclerosis: A transversal study from the prospective Barcelona CIS cohort.

PMID: 39907218
Journal: Multiple Sclerosis Journal
Year: 2025
Reference: Mult Scler. 2025 Feb 5:13524585251314749. doi: 10.1177/13524585251314749.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo, M feminine Jesus; Arino, Helena; Arrambide, Georgina; Auger, Cristina; Bollo, Luca; Carbonell-Mirabent, Pere; Carvajal, Rene; Castillo, Joaquin; Cobo-Calvo, Alvaro; Comabella, Manuel et al.
DOI: 10.1177/13524585251314749

Unmasking paramagnetic rim multiple sclerosis lesions: the advantages of quantitative susceptibility mapping over phase imaging.

PMID: 39916750
Journal: Brain Communications
Year: 2025
Reference: Brain Commun. 2025 Jan 27;7(1):fcaf037. doi: 10.1093/braincomms/fcaf037. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Pareto, Deborah; Rovira, Alex et al.
DOI: 10.1093/braincomms/fcaf037

Late/delayed gadolinium enhancement in MRI after intravenous administration of extracellular gadolinium-based contrast agents: is it worth waiting?

PMID: 38386150
Journal: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
Year: 2024
Reference: MAGMA. 2024 Feb 22. doi: 10.1007/s10334-024-01151-0.
Impact factor:
Publication type: Paper in international publication
Authors: Dekkers, Ilona A; Mallio, Carlo Augusto; Parillo, Marco; Quattrocchi, Carlo Cosimo; Rovira, Alex; van der Molen, Aart J et al.
DOI: 10.1007/s10334-024-01151-0

T1/T2-weighted ratio: A feasible MRI biomarker in multiple sclerosis.

PMID: 38389172
Journal: Multiple Sclerosis Journal
Year: 2024
Reference: Mult Scler. 2024 Feb 22:13524585241233448. doi: 10.1177/13524585241233448.
Impact factor:
Publication type: Paper in international publication
Authors: Boaventura, Mateus; Pareto, Deborah; Rimkus, Carolina de Medeiros; Rovira, Alex; Sastre-Garriga, Jaume et al.
DOI: 10.1177/13524585241233448

Defining a standard set of health outcomes for patients with relapsing-remitting multiple sclerosis.

PMID: 38401203
Journal: Multiple Sclerosis and Related Disorders
Year: 2024
Reference: Mult Scler Relat Disord. 2024 Feb 13;84:105501. doi: 10.1016/j.msard.2024.105501.
Impact factor:
Publication type: Paper in international publication
Authors: Becerril Rios, Noelia; Benedito-Palos, Laura; Borges Guerra, Monica; Carrascal Rueda, Pedro; Comellas, Marta; Delgado Sanchez, Olga; Echeto, Ainara; Llaneza Gonzalez, Miguel; Meca Lallana, Virgina; Morell Baladron, Alberto et al.
DOI: 10.1016/j.msard.2024.105501

Trans-Synaptic Degeneration in the Visual Pathway in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

PMID: 38447105
Journal: NEUROLOGY
Year: 2024
Reference: Neurology. 2024 Apr 9;102(7):e209156. doi: 10.1212/WNL.0000000000209156. Epub 2024 Mar 6.
Impact factor:
Publication type: Paper in international publication
Authors: Acevedo, Breogan Rodriguez; Alberich, Manel; Alvarez, Javier V; Arrambide, Georgina; Auger, Cristina; Bollo, Luca; Cabello, Sergio; Castillo, Joaquin; Cobo-Calvo, Alvaro; Comabella, Manuel et al.
DOI: 10.1212/WNL.0000000000209156

Increased cytomegalovirus immune responses at disease onset are protective in the long-term prognosis of patients with multiple sclerosis.

PMID: 36344261
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Mar;94(3):173-180. doi: 10.1136/jnnp-2022-330205. Epub 2022 Nov 7.
Impact factor:
Publication type: Paper in international publication
Authors: Carbonell-Mirabent, Pere; Comabella, Manuel; Fissolo, Nicolas; Lunemann, Jan D; Malhotra, Sunny; Montalban, Xavier; Rovira, Alex; Sao Aviles, Augusto; Tintore, Mar et al.
DOI: 10.1136/jnnp-2022-330205

Spinal cord reserve in multiple sclerosis.

PMID: 36690430
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Jul;94(7):502-510. doi: 10.1136/jnnp-2022-330613. Epub 2023 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Auger, Cristina; Carbonell-Mirabent, Pere; Garcia-Vidal, Aran; Montalban, Xavier; Pareto, Deborah; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar; Vidal-Jordana, Angela et al.
DOI: 10.1136/jnnp-2022-330613

Using The Virtual Brain to study the relationship between structural and functional connectivity in patients with multiple sclerosis: a multicenter study.

PMID: 36813475
Journal: CEREBRAL CORTEX
Year: 2023
Reference: Cereb Cortex. 2023 Jun 8;33(12):7322-7334. doi: 10.1093/cercor/bhad041.
Impact factor:
Publication type: Paper in international publication
Authors: Deco, Gustavo; Filippi, Massimo; Foster, Michael A; Gonzalez-Escamilla, Gabriel; Groppa, Sergiu; Harbo, Hanne F; Hogestol, Einar A; Llufriu, Sara; Marti-Juan, Gerard; Martinez-Heras, Eloy et al.
DOI: 10.1093/cercor/bhad041

Deciphering multiple sclerosis disability with deep learning attention maps on clinical MRI.

PMID: 36940621
Journal: NeuroImage-Clinical
Year: 2023
Reference: Neuroimage Clin. 2023;38:103376. doi: 10.1016/j.nicl.2023.103376. Epub 2023 Mar 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Coll, Llucia; Coll, Llucia; Comabella, Manuel; Galan, Ingrid et al.
DOI: 10.1016/j.nicl.2023.103376

Uncovertebral synovitis: A rare cause of acute neck pain.

PMID: 36146974
Journal: The journal of the Royal College of Physicians of Edinburgh
Year: 2022
Reference: J R Coll Physicians Edinb. 2022 Mar;52(1):48-49. doi: 10.1177/14782715221088975.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Calderon, Willem; Lozada-Martinez, Ivan; Parizel, Paul M et al.
DOI: 10.1177/14782715221088975

Detection of lesions in the optic nerve with magnetic resonance imaging using a 3D convolutional neural network.

PMID: 36126515
Journal: NeuroImage-Clinical
Year: 2022
Reference: Neuroimage Clin. 2022;36:103187. doi: 10.1016/j.nicl.2022.103187. Epub 2022 Sep 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Calderon, Willem; Camara, Oscar; Frias, Marcos; Garcia-Vidal, Aran; Marti-Juan, Gerard; Montalban, Xavier; Pareto, Deborah; Piella, Gemma; Rovira, Alex et al.
DOI: 10.1016/j.nicl.2022.103187

Commentary: predictor of shunt response in idiopathic normal pressure hydrocephalus.

PMID: 36104627
Journal: NEURORADIOLOGY
Year: 2022
Reference: Neuroradiology. 2022 Nov;64(11):2097-2099. doi: 10.1007/s00234-022-03051-3.
Impact factor:
Publication type: Editorail in international publication
Authors: Hodel, Jerome; Rovira, Alex et al.
DOI: 10.1007/s00234-022-03051-3

Gadolinium-enhanced brain lesions in multiple sclerosis relapse.

PMID: 36064284
Journal: NEUROLOGIA
Year: 2022
Reference: Neurologia (Engl Ed). 2022 Sep;37(7):557-563. doi: 10.1016/j.nrleng.2021.10.005.
Impact factor:
Publication type: Paper in international publication
Authors: Batlle-Nadal, J; Blanco, Y; Brieva-Ruiz, L; Cano-Orgaz, A; Capellades, J; Carmona, O; Gea, M; Hervas-Garcia, J V; Martin-Aguilar, L; Massuet-Vilamajo, A et al.
DOI: 10.1016/j.nrleng.2021.10.005

Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers.

PMID: 34556662
Journal: Scientific Data
Year: 2021
Reference: Sci Data. 2021 Sep 23;8(1):251. doi: 10.1038/s41597-021-01044-0.
Impact factor:
Publication type: Letter or abstract
Authors: Abramovic, Mihael; Alonso-Ortiz, Eva; Arneitz, Carina; Atcheson, Nicole; Barlow, Laura; Barry, Robert L; Barth, Markus; Battiston, Marco; Buchel, Christian; Budde, Matthew et al.
DOI: 10.1038/s41597-021-01044-0

Effect of Changes in MS Diagnostic Criteria Over 25 Years on Time to Treatment and Prognosis in Patients With Clinically Isolated Syndrome.

PMID: 34521693
Journal: NEUROLOGY
Year: 2021
Reference: Neurology. 2021 Oct 26;97(17):e1641-e1652. doi: 10.1212/WNL.0000000000012726. Epub 2021 Sep 14.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo, Maria Jesus; Arrambide, Georgina; Auger, Cristina; Carbonell, Pere; Castillo, Joaquin; Cobo-Calvo, Alvaro; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Montalban, Xavier et al.
DOI: 10.1212/WNL.0000000000012726

Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers.

PMID: 34508107
Journal: Scientific Data
Year: 2021
Reference: Sci Data. 2021 Sep 10;8(1):242. doi: 10.1038/s41597-021-01026-2.
Impact factor:
Publication type: Letter or abstract
Authors: Abramovic, Mihael; Alonso-Ortiz, Eva; Arneitz, Carina; Atcheson, Nicole; Barlow, Laura; Barry, Robert L; Barth, Markus; Battiston, Marco; Buchel, Christian; Budde, Matthew et al.
DOI: 10.1038/s41597-021-01026-2

Quantification of Cervical Cord Cross-Sectional Area: Which Acquisition, Vertebra Level, and Analysis Software? A Multicenter Repeatability Study on a Traveling Healthy Volunteer.

PMID: 34421797
Journal: Frontiers in Neurology
Year: 2021
Reference: Front Neurol. 2021 Aug 4;12:693333. doi: 10.3389/fneur.2021.693333. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Bellenberg, Barbara; Brouwer, Iman; Filippi, Massimo; Gandini Wheeler-Kingshott, Claudia A M; Kappos, Ludwig; Lukas, Carsten; Pareto, Deborah; Parmar, Katrin; Prados, Ferran et al.
DOI: 10.3389/fneur.2021.693333

The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS.

PMID: 31610739
Journal: Multiple Sclerosis Journal
Year: 2020
Reference: Mult Scler. 2020 Nov;26(13):1658-1669. doi: 10.1177/1352458519877810. Epub 2019 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Anglada, Elisenda; Arevalo, Maria Jesus; Arrambide, Georgina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaquin; Comabella, Manuel; de Barros, Andrea; Espejo, Carmen; Galan, Ingrid et al.
DOI: 10.1177/1352458519877810

Clinical-radiological approach to nontraumatic myelopathy.

PMID: 33069364
Journal: Radiologia
Year: 2020
Reference: Radiologia. 2020 Nov - Dec;62(6):464-480. doi: 10.1016/j.rx.2020.07.004. Epub 2020 Oct 14.
Impact factor:
Publication type: Review in national publication
Authors: Garrido Morro, I; Guzman de Villoria Lebiedziejewski, J; Herrera Herrera, I; Ordonez Gonzalez, C; Rovira, A et al.
DOI: 10.1016/j.rx.2020.07.004

Isolated cerebral mucormycosis associated with intravenous drug use.

PMID: 33067115
Journal: JOURNAL DE MYCOLOGIE MEDICALE
Year: 2020
Reference: J Mycol Med. 2020 Dec;30(4):101046. doi: 10.1016/j.mycmed.2020.101046. Epub 2020 Oct 6.
Impact factor:
Publication type: Letter or abstract
Authors: Auger, C; Dura-Miralles, X; Escola-Verge, L; Fernandez-Hidalgo, N; Lung, M; Martin-Gomez, M-T; Martinez-Ricarte, F; Moreno, D et al.
DOI: 10.1016/j.mycmed.2020.101046

Relationship of estrogen synthesis capacity in the brain with obesity and self-control in men and women.

PMID: 32868418
Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Year: 2020
Reference: Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22962-22966. doi: 10.1073/pnas.2006117117. Epub 2020 Aug 31.
Impact factor:
Publication type: Paper in international publication
Authors: Alexoff, David L; Alia-Klein, Nelly; Biegon, Anat; Fowler, Joanna S; Hildebrandt, Tom; Kim, Sung Won; Logan, Jean; Pareto, Deborah; Preston-Campbell, Rebecca; Wang, Gene-Jack et al.
DOI: 10.1073/pnas.2006117117

Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis.

PMID: 31424490
Journal: JAMA Neurology
Year: 2019
Reference: JAMA Neurol. 2019 Dec 1;76(12):1446-1456. doi: 10.1001/jamaneurol.2019.2478.
Impact factor:
Publication type: Paper in international publication
Authors: Calabrese, Massimiliano; Clarke, Margareta A; De Stefano, Nicola; Enzinger, Christian; Evangelou, Nikos; Giorgio, Antonio; Kappos, Ludwig; Meier, Dominik; Montalban, Xavier; Paul, Friedemann et al.
DOI: 10.1001/jamaneurol.2019.2478

Longitudinal spinal cord atrophy in multiple sclerosis using the generalised boundary shift integral.

PMID: 31385358
Journal: ANNALS OF NEUROLOGY
Year: 2019
Reference: Ann Neurol. 2019 Nov;86(5):704-713. doi: 10.1002/ana.25571. Epub 2019 Aug 22.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Barkhof, Frederik; Brownlee, Wallace J; Ciccarelli, Olga; Ciccarelli, Olga; Filippi, Massimo; Filippi, Massimo; Frederiksen, Jette; Gallo, Antonio; Gandini Wheeler-Kingshott, Claudia A M et al.
DOI: 10.1002/ana.25571

Acromegaly remission, SIADH and pituitary function recovery after macroadenoma apoplexy

PMID: 31310082
Journal: Endocrinology, diabetes & metabolism case repo
Year: 2019
Reference: Endocrinol Diabetes Metab Case Rep. 2019 Jul 15;2019(1). doi: 10.1530/EDM-19-0057.
Impact factor:
Publication type: Paper in international publication
Authors: Arikan, F; Biagetti, B; Sanz-Sapera, E; Sarria-Estrada, S et al.
DOI: 10.1530/EDM-19-0057

Use of gadolinium for MRI diagnostic or surveillance studies in patients with MS.

PMID: 31285397
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 Aug 6;93(6):239-240. doi: 10.1212/WNL.0000000000007891. Epub 2019 Jul 8.
Impact factor:
Publication type: Editorail in international publication
Authors: Haider, Lukas; Naismith, Robert T; Rovira, Alex et al.
DOI: 10.1212/WNL.0000000000007891

Urgent challenges in quantification and interpretation of brain grey matter atrophy in individual MS patients using MRI.

PMID: 29984155
Journal: NeuroImage-Clinical
Year: 2018
Reference: Neuroimage Clin. 2018 Apr 26;19:466-475. doi: 10.1016/j.nicl.2018.04.023. eCollection 2018.
Impact factor:
Publication type: Review in national publication
Authors: Amiri, Houshang; Barkhof, Frederik; Battaglini, Marco; Bendfeldt, Kerstin; Calabrese, Massimiliano; de Sitter, Alexandra; de Stefano, Nicola; Enzinger, Christian; Filippi, Massimo; Gandini Wheeler-Kingshott, Claudia A M et al.
DOI: 10.1016/j.nicl.2018.04.023

Brain atrophy 15 years after CIS: Baseline and follow-up clinico-radiological correlations.

PMID: 28445084
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 May;24(6):721-727. doi: 10.1177/1352458517707070. Epub 2017 Apr 26.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Huerga, Elena; Mitjana, Raquel; Montalban, Xavier; Otero-Romero, Susana; Pareto, Deborah; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar et al.
DOI: 10.1177/1352458517707070

Progression of regional grey matter atrophy in multiple sclerosis.

PMID: 29741648
Journal: BRAIN
Year: 2018
Reference: Brain. 2018 Jun 1;141(6):1665-1677. doi: 10.1093/brain/awy088.
Impact factor:
Publication type: Paper in international publication
Authors: Alexander, Daniel C; Barkhof, Frederik; Battaglini, Marco; Brownlee, Wallace J; Cawley, Niamh; Chard, Declan; Ciccarelli, Olga; De Angelis, Floriana; De Stefano, Nicola; Enzinger, Christian et al.
DOI: 10.1093/brain/awy088

Measurement of Whole-Brain and Gray Matter Atrophy in Multiple Sclerosis: Assessment with MR Imaging.

PMID: 29714673
Journal: RADIOLOGY
Year: 2018
Reference: Radiology. 2018 Aug;288(2):554-564. doi: 10.1148/radiol.2018172468. Epub 2018 May 1.
Impact factor:
Publication type: Paper in international publication
Authors: De Stefano, Nicola; Filippi, Massimo; Horsfield, Mark A; Pagani, Elisabetta; Palace, Jacqueline; Rocca, Maria A; Rovira, Alex; Sastre-Garriga, Jaume; Sima, Diana; Smeets, Dirk et al.
DOI: 10.1148/radiol.2018172468

Grey matter atrophy is associated with disability increase in natalizumab-treated patients.

PMID: 27354019
Journal: Multiple Sclerosis Journal
Year: 2017
Reference: Mult Scler. 2017 Apr;23(4):556-566. doi: 10.1177/1352458516656808. Epub 2016 Jul 11.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Ciampi, Ethel; Montalban, Xavier; Pareto, Deborah; Rio, Jordi; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar; Tur, Carmen; Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458516656808

Criteria for training and accreditation in Interventional Neuroradiology-Neurointervention, approved by the Spanish Group of Interventional Neuroradiology (GENI), the Spanish Society of Neuroradiology (SENR), the Spanish Group of Cerebrovascular Diseases (GEECV), the Spanish Society of Neurology (SEN), and the vascular disease specialists in the Spanish Society of Neurosurgery (SENEC). Requirements for accreditation in Interventional Neuroradiology-Neurointervention for institutions and specialists.

PMID: 27137521
Journal: NEUROLOGIA
Year: 2017
Reference: Neurologia. 2017 Mar;32(2):106-112. doi: 10.1016/j.nrl.2016.02.005. Epub 2016 Apr 30.
Impact factor:
Publication type: Review in national publication
Authors: Arenillas, J; Arikan-Abello, F; Fernandez Alen, J; Fortea, F; Gallego, J; Gonzalez, A; Masjuan, J; Rovira, A et al.
DOI: 10.1016/j.nrl.2016.02.005

Chelated or dechelated gadolinium deposition.

PMID: 29165253
Journal: LANCET NEUROLOGY
Year: 2017
Reference: Lancet Neurol. 2017 Dec;16(12):955. doi: 10.1016/S1474-4422(17)30364-2. Epub 2017 Nov 14.
Impact factor:
Publication type: Letter or abstract
Authors: Clement, Olivier; Quattrocchi, Carlo Cosimo; Radbruch, Alexander; Roberts, Donna R; Rovira, Alex et al.
DOI: 10.1016/S1474-4422(17)30364-2

Lesion topographies in multiple sclerosis diagnosis: A reappraisal.

PMID: 29101276
Journal: NEUROLOGY
Year: 2017
Reference: Neurology. 2017 Dec 5;89(23):2351-2356. doi: 10.1212/WNL.0000000000004715. Epub 2017 Nov 3.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Castillo, Joaquin; Comabella, Manuel; de Barros, Andrea; Galan, Ingrid; Midaglia, Luciana; Mitjana, Raquel; Montalban, Xavier; Mulero, Patricia et al.
DOI: 10.1212/WNL.0000000000004715

MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes.

PMID: 26604134
Journal: HUMAN MOLECULAR GENETICS
Year: 2016
Reference: Hum Mol Genet. 2016 Jan 15;25(2):308-16. doi: 10.1093/hmg/ddv473. Epub 2015 Nov 24.
Impact factor:
Publication type: Paper in international publication
Authors: Auger, Cristina; Aymerich, Xavier; Canto, Ester; Castillo, Joaquin; Comabella, Manuel; Fissolo, Nicolas; Montalban, Xavier; Nurtdinov, Ramil; Picon, Carmen; Rio, Jordi et al.
DOI: 10.1093/hmg/ddv473

[Atypical ganglioglioma with BRAF V600E mutation: a case report and review of the literature].

PMID: 27149188
Journal: REVISTA DE NEUROLOGIA
Year: 2016
Reference: Rev Neurol. 2016 May 16;62(10):455-9.
Impact factor:
Publication type: Paper in national publication
Authors: Auger, C; Cicuendez, M; Cordero, E; Martinez-Ricarte, F; Martinez-Saez, E; Radoi, A; Sahuquillo, J; Toledo, M et al.
DOI: 10.33588/rn.6210.2015449

Power estimation for non-standardized multisite studies.

PMID: 27039700
Journal: NEUROIMAGE
Year: 2016
Reference: Neuroimage. 2016 Jul 1;134:281-94. doi: 10.1016/j.neuroimage.2016.03.051. Epub 2016 Apr 1.
Impact factor:
Publication type: Paper in international publication
Authors: Amann, Michael; Bakshi, Rohit; Beyer, Mona K; Bischof, Antje; Carriero, Alessandro; Comabella, Manuel; Cournu-Rebeix, Isabelle; Crane, Jason C; D'Alfonso, Sandra; Demaerel, Philippe et al.
DOI: 10.1016/j.neuroimage.2016.03.051

[Response to treatment with interferon beta in patients with multiple sclerosis. Validation of the Rio Score].

PMID: 27439483
Journal: REVISTA DE NEUROLOGIA
Year: 2016
Reference: Rev Neurol. 2016 Aug 16;63(4):145-50.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez-Cermeno, J C; Arroyo, R; Arroyo, R; Blanco, Y; Comabella, M; Diaz, R M; Fernandez, O; Garcia-Merino, J A; Izquierdo, G; Montalban, X et al.
DOI:

Similar biological effect of high-dose oral versus intravenous methylprednisolone in multiple sclerosis relapses.

PMID: 25145693
Journal: MULT SCLER J
Year: 2015
Reference: Mult Scler. 2015 Apr;21(5):646-50. doi: 10.1177/1352458514546786. Epub 2014 Aug 21.
Impact factor:
Publication type: Paper in international publication
Authors: Brieva, L; Cano, A; Carmona, O; Grau-Lopez, L; Hervas, J V; Martinez-Caceres, E M; Ramio-Torrenta, L; Ramo-Tello, C; Rovira, A; Saiz, A et al.
DOI: 10.1177/1352458514546786

Reproducibility of qualitative assessments of temporal lobe atrophy in MRI studies.

PMID: 24970598
Journal: Radiologia
Year: 2015
Reference: Radiologia. 2015 May-Jun;57(3):225-8. doi: 10.1016/j.rx.2014.04.002. Epub 2014 Jun 23.
Impact factor:
Publication type: Letter or abstract
Authors: Acevedo, C; Auger, C; Frascheri, L; Mitjana, R; Rovira, A; Sarria-Estrada, S; Siurana, S et al.
DOI: 10.1016/j.rx.2014.04.002

Reflex seizures triggered by cutaneous stimuli.

PMID: 26590698
Journal: SEIZURE-EUR J EPILEP
Year: 2015
Reference: Seizure. 2015 Dec;33:72-5. doi: 10.1016/j.seizure.2015.10.013. Epub 2015 Oct 25.
Impact factor:
Publication type: Paper in international publication
Authors: Gonzalez-Cuevas, M; Sala-Padro, J; Salas-Puig, J; Santamarina, E; Sarria, S; Sueiras-Gil, M; Toledo, M et al.
DOI: 10.1016/j.seizure.2015.10.013

[Visual epileptic seizures. Signs and symptoms, and clinical implications].

PMID: 25760720
Journal: REV NEUROLOGIA
Year: 2015
Reference: Rev Neurol. 2015 Mar 16;60(6):257-62.
Impact factor:
Publication type: Paper in national publication
Authors: Cambrodi-Masip, Roser; Gonzalez-Cuevas, Montserrat; Quintana, Manuel; Salas-Puig, Javier; Santamarina, Estevo; Sarria, Silvana; Sueiras-Gil, Maria; Toledo, Manuel et al.
DOI: 10.33588/rn.6006.2014404

[Consensus statement on the clinical management of human immunodeficiency virus-associated neurocognitive disorders].

PMID: 23642283
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2014
Reference: Enferm Infecc Microbiol Clin. 2014 Jan;32(1):37-47. doi: 10.1016/j.eimc.2013.03.005. Epub 2013 Apr 30.
Impact factor:
Publication type: Paper in national publication
Authors: Alcolea Rodriguez, Daniel; Alonso Villaverde, Carlos; Antela Lopez, Antonio; Arribas Lopez, Jose Ramon; Blanch Andreu, Jordi; Casado Osorio, Jose Luis; de Leon-Naranjo, Fernando Lozano; Galindo Puerto, M Jose; Garolera i Freixa, Maite; Goenaga Sanchez, Miguel Angel et al.
DOI: 10.1016/j.eimc.2013.03.005

Functional correlates of cognitive dysfunction in multiple sclerosis: A multicenter fMRI Study.

PMID: 25045065
Journal: HUMAN BRAIN MAPPING
Year: 2014
Reference: Hum Brain Mapp. 2014 Dec;35(12):5799-814. doi: 10.1002/hbm.22586. Epub 2014 Jul 18.
Impact factor:
Publication type: Paper in international publication
Authors: Abdel-Aziz, Khaled; Arevalo, Maria J; Barkhof, Frederik; Bisecco, A; Ciccarelli, Olga; Comi, G; Damjanovic, D; Enzinger, Christian; Fazekas, Franz; Filippi, Massimo et al.
DOI: 10.1002/hbm.22586

Automatic multiple sclerosis lesion detection in brain MRI by FLAIR thresholding.

PMID: 24813718
Journal: COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
Year: 2014
Reference: Comput Methods Programs Biomed. 2014 Jul;115(3):147-61. doi: 10.1016/j.cmpb.2014.04.006. Epub 2014 Apr 19.
Impact factor:
Publication type: Paper in international publication
Authors: Cabezas, Mariano; Freixenet, Jordi; Llado, Xavier; Oliver, Arnau; Ramio-Torrenta, Lluis; Roura, Eloy; Rovira, Alex; Vilanova, Joan C et al.
DOI: 10.1016/j.cmpb.2014.04.006

Determinants of iron accumulation in deep grey matter of multiple sclerosis patients.

PMID: 24787429
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Nov;20(13):1692-8. doi: 10.1177/1352458514531085. Epub 2014 Apr 30.
Impact factor:
Publication type: Paper in international publication
Authors: Amann, Michael; Barkhof, Frederik; Ciccarelli, Olga; de Graaf, Wolter L; Enzinger, Christian; Fazekas, Franz; Filippi, Massimo; Frederiksen, Jette L; Kappos, Ludwig; Khalil, Michael et al.
DOI: 10.1177/1352458514531085

Recommendations to improve imaging and analysis of brain lesion load and atrophy in longitudinal studies of multiple sclerosis.

PMID: 23263472
Journal: JOURNAL OF NEUROLOGY
Year: 2013
Reference: J Neurol. 2013 Oct;260(10):2458-71. doi: 10.1007/s00415-012-6762-5. Epub 2012 Dec 21.
Impact factor:
Publication type: Paper in international publication
Authors: Ashburner, J; Barkhof, F; Barkhof, F; Battaglini, M; Ciccarelli, O; de Stefano, N; de Stefano, N; Enzinger, C; Fazekas, F; Filippi, M et al.
DOI: 10.1007/s00415-012-6762-5

[How to prepare an oral presentation and a conference].

PMID: 23517736
Journal: Radiologia
Year: 2013
Reference: Radiologia. 2013 Jun;55 Suppl 1:S2-7. doi: 10.1016/j.rx.2013.01.004. Epub 2013 Mar 19.
Impact factor:
Publication type: Letter or abstract
Authors: Auger, C; Naidich, T P; Rovira, A et al.
DOI: 10.1016/j.rx.2013.01.004

Atypical idiopathic inflammatory demyelinating lesions: prognostic implications and relation to multiple sclerosis.

PMID: 23620065
Journal: JOURNAL OF NEUROLOGY
Year: 2013
Reference: J Neurol. 2013 Aug;260(8):2016-22. doi: 10.1007/s00415-013-6918-y. Epub 2013 Apr 26.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Enzinger, Christian; Fazekas, Franz; Fillipp, Massimo; Flores, Jose; Frederiksen, Jette; Gama, Hugo; Gass, Achim; Miller, David H; Montalban, Xavier et al.
DOI: 10.1007/s00415-013-6918-y

Clinical impact of early brain atrophy in clinically isolated syndromes.

PMID: 23652215
Journal: Multiple Sclerosis Journal
Year: 2013
Reference: Mult Scler. 2013 Dec;19(14):1878-86. doi: 10.1177/1352458513488231. Epub 2013 May 7.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, G; Auger, C; Castillo, J; Edo, M C; Horga, A; Huerga, E; Montalban, X; Nos, C; Perez-Miralles, F; Perkal, H et al.
DOI: 10.1177/1352458513488231

Nigrostriatal pathway dysfunction in a methanol-induced delayed dystonia-parkinsonism.

PMID: 22976778
Journal: MOVEMENT DISORDERS
Year: 2012
Reference: Mov Disord. 2012 Sep 1;27(10):1220-1. doi: 10.1002/mds.25049.
Impact factor:
Publication type: Editorail in international publication
Authors: Castell-Conesa, Joan; Cuberas-Borros, Gemma; Franquet, Elisa; Hernandez-Vara, Jorge; Lorenzo-Bosquet, Carlos; Rovira, Alex; Salvado-Figueres, Maria et al.
DOI: 10.1002/mds.25049

MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice.

PMID: 22016411
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2012
Reference: AJNR Am J Neuroradiol. 2012 May;33(5):803-17. Epub 2011 Oct 20.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.3174/ajnr.A2640

Value of NMO-IgG determination at the time of presentation as CIS.

PMID: 22551725
Journal: NEUROLOGY
Year: 2012
Reference: Neurology. 2012 May 15;78(20):1608-11. doi: 10.1212/WNL.0b013e3182563b32. Epub 2012 May 2.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1212/WNL.0b013e3182563b32

MMP-2/MMP-9 plasma level and brain expression in Cerebral Amyloid Angiopathy-associated hemorrhagic stroke.

PMID: 21707819
Journal: BRAIN PATHOLOGY
Year: 2012
Reference: Brain Pathol. 2012 Mar;22(2):133-41. doi: 10.1111/j.1750-3639.2011.00512.x. Epub 2011 Sep 15.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1750-3639.2011.00512.x

Interferon Beta-1b for the Treatment of Primary Progressive Multiple Sclerosis: Five-Year Clinical Trial Follow-up.

PMID: 22084124
Journal: ARCHIVES OF NEUROLOGY
Year: 2011
Reference: Arch Neurol. 2011 Nov;68(11):1421-7.
Impact factor:
Publication type: Paper in international publication
Authors: Aymerich, Francesc Xavier; Brieva, Luis; Calle, David; Comabella, Manuel; Galan, Ingrid; Montalban, Xavier; Nos, Carlos; Perkal, Hector; Rio, Jordi; Rovira, Alex et al.
DOI: 10.1001/archneurol.2011.241

[Spanish multi-centre observational study of the first attacks suggestive of multiple sclerosis: the PREM cohort].

PMID: 22052172
Journal: REVISTA DE NEUROLOGIA
Year: 2011
Reference: Rev Neurol. 2011 Nov 16;53(10):577-83.
Impact factor:
Publication type: Paper in national publication
Authors: Arroyo-Gonzalez, R; Aymerich, X; Bonaventura, I; de Andres, C; En Nombre Del Grupo de Investigadores Del Estudio ; Escartin, A; Escudero-Torrella, J; Farres, J; Lacruz, F; Marco-Igual, M et al.
DOI:

MR brain iron mapping in MS: A potential neurodegenerative marker or just another technique?

PMID: 21975201
Journal: NEUROLOGY
Year: 2011
Reference: Neurology. 2011 Nov 1;77(18):1660-1. Epub 2011 Oct 5.
Impact factor:
Publication type: Editorail in international publication
Authors: ; et al.
DOI: 10.1212/WNL.0b013e318236f120

Neuroimaging in acute liver failure.

PMID: 21945201
Journal: NEUROCHEMISTRY INTERNATIONAL
Year: 2011
Reference: Neurochem Int. 2011 Dec;59(8):1175-80. Epub 2011 Sep 14.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; et al.
DOI: 10.1016/j.neuint.2011.09.003

[Demyelinating lesions as incidental findings in magnetic resonance imaging: a study of 11 cases with clinico-radiological follow-up and a review of the literature]

PMID: 20645263
Journal: REVISTA DE NEUROLOGIA
Year: 2010
Reference: Rev Neurol. 2010 Aug;51(3):129-34.
Impact factor:
Publication type: Paper in national publication
Authors: Auger-Acosta, Cristina; Castillo, Joaquin; Edo, Mari Carmen; Horga-Hernandez, Alejandro; Mitjana, Raquel; Montalban, Xavier; Rio-Izquierdo, Jordi; Rovira, Alex; Sierra-Marcos, Alba; Tintore, Mar et al.
DOI:

[Recommendations for using and interpreting magnetic resonance imaging in multiple sclerosis]

PMID: 20609303
Journal: NEUROLOGIA
Year: 2010
Reference: Neurologia. 2010 May;25(4):248-65.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez-Cermeno, J C; Izquierdo, G; Prieto, J M; Rovira, A; Tintore, M et al.
DOI:

Clinical features of CIS of the brainstem/cerebellum of the kind seen in MS.

PMID: 19946780
Journal: JOURNAL OF NEUROLOGY
Year: 2010
Reference: J Neurol. 2010 May;257(5):742-6. Epub 2009 Nov 28.
Impact factor:
Publication type: Paper in international publication
Authors: Castillo, J; Comabella, M; Horga, A; Montalban, X; Nos, C; Perkal, H; Rio, J; Rovira, A; Sastre-Garriga, Jaume; Tellez, N et al.
DOI: 10.1007/s00415-009-5403-0

Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes.

PMID: 20530323
Journal: NEUROLOGY
Year: 2010
Reference: Neurology. 2010 Jun 8;74(23):1868-1876.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1212/WNL.0b013e3181e24136

[Diffuse astrocytoma presenting as an optic-spinal syndrome]

PMID: 19319816
Journal: REVISTA DE NEUROLOGIA
Year: 2009
Reference: Rev Neurol. 2009 Apr 1-15;48(7):354-6.
Impact factor:
Publication type: Paper in national publication
Authors: Alonso, J; Martinez, E; Montalban, X; Parees, I; Rovira, A et al.
DOI:

MR imaging findings in 56 patients with Wernicke encephalopathy: nonalcoholics may differ from alcoholics.

PMID: 18945789
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2009
Reference: AJNR Am J Neuroradiol. 2009 Jan;30(1):171-6.
Impact factor:
Publication type: Paper in international publication
Authors: Bertolini, M; Carollo, C; Gallucci, M; Pipitone, N; Rovira, A; Santa Cruz, D; Zuccoli, G et al.
DOI: 10.3174/ajnr.A1280

Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis.

PMID: 19218803
Journal: CEREBROVASCULAR DISEASES
Year: 2009
Reference: Cerebrovasc Dis. 2009;27(4):368-74.
Impact factor:
Publication type: Paper in international publication
Authors: Albers, G W; Berkefeld, J; Derex, L; Fiehler, J; Gass, A; Kastrup, A; Kim, J S; Lansberg, M G; Liebeskind, D S; Lorenz, M W et al.
DOI: 10.1159/000202427

Measures in the first year of therapy predict the response to interferon beta in MS.

PMID: 19542263
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Jul;15(7):848-53.
Impact factor:
Publication type: Paper in international publication
Authors: Aymerich, X; Castillo, J; Comabella, M; Horga, A; Montalban, X; Nos, C; Rio, J; Rovira, A; Sastre-Garriga, J; Tintore, M et al.
DOI: 10.1177/1352458509104591

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The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

Els doctors Xavier Montalban, Àlex Rovira i Mar Tintoré han estat reconeguts en la categoria de Neurociències i Comportament, i el doctor Jordi Rello en la categoria Interdisciplinària.

The program, promoted by Biocat in collaboration with CIMIT (Boston), is aimed at entrepreneurs in the process of bringing their technology to market in the next few years.

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Magnetic Resonance image analysis