Skip to main content

Neurotraumatology and Neurosurgery Research Unit (UNINN)

The Neurotraumatology and Neurosurgery Research Unit (UNINN) is a translational research group fully integrated into the European research community and accredited as a Consolidated Research Group since 2005.

The UNINN conduct both basic and clinical research, with the aim of transferring benchside discoveries to the bedside. We have robust intramural synergies, national collaborations with basic scientists, and international collaborations and alliances with researchers from multiple countries and institutions with whom we share common research goals.

Our research unit participates in multinational clinical trials funded by the pharmaceutical industry and the European Union (EU). Our research unit is highly focused on developing and using new technologies to improve the assessment of clinical outcomes, incorporating quality of life measures, and patient-reported outcomes. We also maintain an important collection of brain tissue samples, serum, LCR, and microdialysates from the cerebral extracellular space of neurocritical patients. 

Publications

Diagnosis and treatment of Chiari malformation and syringomyelia in adults: international consensus document.

PMID: 34129128
Journal: NEUROLOGICAL SCIENCES
Year: 2022
Reference: Neurol Sci. 2022 Feb;43(2):1327-1342. doi: 10.1007/s10072-021-05347-3. Epub 2021 Jun 15.
Impact factor:
Publication type: Paper in international publication
Authors: Barbanera, Andrea; Bertuccio, Alessandro; Chiapparini, Luisa; Ciaramitaro, Palma; Farinotti, Mariangela; Garbossa, Diego; Massimi, Luca; Peretta, Paola; Poca, Maria Antonia; Sahuquillo, Juan et al.
DOI: 10.1007/s10072-021-05347-3

Diagnosis and treatment of Chiari malformation type 1 in children: the International Consensus Document.

PMID: 34097175
Journal: NEUROLOGICAL SCIENCES
Year: 2022
Reference: Neurol Sci. 2022 Feb;43(2):1311-1326. doi: 10.1007/s10072-021-05317-9. Epub 2021 Jun 7.
Impact factor:
Publication type: Paper in international publication
Authors: Caldarelli, Massimo; Canheu, Alexandre Casagrande; Celada, Carlo; Chiapparini, Luisa; Chieffo, Daniela; Ciaramitaro, Palma; Cinalli, Giuseppe; Di Rocco, Federico; Erbetta, Alessandra; Farinotti, Mariangela et al.
DOI: 10.1007/s10072-021-05317-9

Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation.

PMID: 35065038
Journal: LANCET NEUROLOGY
Year: 2022
Reference: Lancet Neurol. 2022 Feb;21(2):153-162. doi: 10.1016/S1474-4422(21)00374-4.
Impact factor:
Publication type: Paper in international publication
Authors: Ackerlund, Cecilia; Adams, Hadie; Adeoye, Opeolu; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe et al.
DOI: 10.1016/S1474-4422(21)00374-4

Correction to: Diagnosis and treatment of Chiari Malformation and syringomyelia in adults: International Consensus Document.

PMID: 34786631
Journal: NEUROLOGICAL SCIENCES
Year: 2022
Reference: Neurol Sci. 2022 Feb;43(2):1483-1484. doi: 10.1007/s10072-021-05724-y.
Impact factor:
Publication type: Letter or abstract
Authors: Barbanera, Andrea; Bertuccio, Alessandro; Bolognese, Paolo; Brodbelt, Andrew; Celada, Carlo; Chiapparini, Luisa; Ciaramitaro, Palma; Cocito, Dario; Curone, Marcella; Devigili, Grazia et al.
DOI: 10.1007/s10072-021-05724-y

Surgical or endovascular management of middle cerebral artery aneurysms: A randomized comparison.

PMID: 33556601
Journal: World Neurosurgery
Year: 2021
Reference: World Neurosurg. 2021 May;149:e521-e534. doi: 10.1016/j.wneu.2021.01.142. Epub 2021 Feb 5.
Impact factor:
Publication type: Paper in international publication
Authors: Altschul, David J; Arikan, Fuat; Ashforth, Robert A; Bilocq, Alain; Boisseau, William; Bojanowski, Michel W; Bricout, Nicolas; Chaalala, Chiraz; Chagnon, Miguel; Chan, Vivien Ky et al.
DOI: 10.1016/j.wneu.2021.01.142

CO2-induced intracranial hypertension and high-amplitude B-waves in a patient with Chiari 1 malformation and sleep apnea syndrome that resolved following CPAP therapy.

PMID: 33528722
Journal: ACTA NEUROCHIRURGICA
Year: 2021
Reference: Acta Neurochir (Wien). 2021 Nov;163(11):3075-3082. doi: 10.1007/s00701-021-04717-2. Epub 2021 Feb 2.
Impact factor:
Publication type: Letter or abstract
Authors: de la Calzada, Maria D; Fernandez-Torrelles, Sara; Ferre, Alex; Moncho, Dulce; Poca, Maria A; Sahuquillo, Juan et al.
DOI: 10.1007/s00701-021-04717-2

Reduced hippocampal subfield volumes and memory performance in preterm children with and without germinal matrix-intraventricular hemorrhage.

PMID: 33510243
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Jan 28;11(1):2420. doi: 10.1038/s41598-021-81802-7.
Impact factor:
Publication type: Paper in international publication
Authors: Delgado, Ignacio; Fernandez de Gamarra-Oca, Lexuri; Junque, Carme; Macaya, Alfons; Ojeda, Natalia; Poca, Maria A; Solana, Elisabeth; Soria-Pastor, Sara; Vazquez, Elida; Zubiaurre-Elorza, Leire et al.
DOI: 10.1038/s41598-021-81802-7

Optic nerve region in multiple sclerosis diagnosis: the utility of visual evoked potentials.

PMID: 33328323
Journal: NEUROLOGY
Year: 2021
Reference: Neurology. 2021 Jan 26;96(4):e482-e490. doi: 10.1212/WNL.0000000000011339. Epub 2020 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Cabello, Sergio; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Moncho, Dulce; Montalban, Xavier; Nos, Carlos et al.
DOI: 10.1212/WNL.0000000000011339

Distal catheter lengthening in pediatric patients with hydrocephalus using a guidewire-assisted technique.

PMID: 32232564
Journal: CHILDS NERVOUS SYSTEM
Year: 2020
Reference: Childs Nerv Syst. 2020 Nov;36(11):2733-2740. doi: 10.1007/s00381-020-04591-w. Epub 2020 Mar 30.
Impact factor:
Publication type: Paper in international publication
Authors: Cano, Paola; Gonzalez, Diego; Munar, Francisca; Poca, Maria A; Rosas, Katiuska; Sahuquillo, Juan et al.
DOI: 10.1007/s00381-020-04591-w

Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury.

PMID: 32201256
Journal: JOURNAL OF CLINICAL EPIDEMIOLOGY
Year: 2020
Reference: J Clin Epidemiol. 2020 Jun;122:95-107. doi: 10.1016/j.jclinepi.2020.03.005. Epub 2020 Mar 20.
Impact factor:
Publication type: Paper in international publication
Authors: Akerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Antoni, Anna; Ao, Braden Te; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa et al.
DOI: 10.1016/j.jclinepi.2020.03.005

Letter to the Editor Regarding: "Safety and Feasibility Assessment of the O-Arm as an Intraoperative Angiography Device in Aneurysm Surgery".

PMID: 32204276
Journal: World Neurosurgery
Year: 2020
Reference: World Neurosurg. 2020 Apr;136:419. doi: 10.1016/j.wneu.2019.12.048.
Impact factor:
Publication type: Letter or abstract
Authors: Vilalta, Jordi et al.
DOI: 10.1016/j.wneu.2019.12.048

Post-operative high blood pressure.

PMID: 32178910
Journal: Revista espanola de anestesiologia y reanimacion
Year: 2020
Reference: Rev Esp Anestesiol Reanim. 2020 May;67 Suppl 1:33-38. doi: 10.1016/j.redar.2019.11.008. Epub 2020 Mar 13.
Impact factor:
Publication type: Letter or abstract
Authors: de Nadal, M et al.
DOI: 10.1016/j.redar.2019.11.008

Perampanel: A therapeutic alternative in refractory status epilepticus associated with MELAS syndrome.

PMID: 30834194
Journal: Epilepsy & behavior case reports
Year: 2019
Reference: Epilepsy Behav Case Rep. 2019 Feb 7;11:92-95. doi: 10.1016/j.ebcr.2019.01.008. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, Laura; Alpuente, Alicia; Guzman, Lorena; Maisterra, Olga; Salas-Puig, Javier; Santamarina, Estevo; Sarria, Silvana; Sueiras, Maria; Toledo, Manuel et al.
DOI: 10.1016/j.ebcr.2019.01.008

Symptomatic delayed coil migration after balloon assisted embolization: An underreported adverse event?

PMID: 29625853
Journal: NEUROCIRUGIA
Year: 2019
Reference: Neurocirugia (Astur). 2019 Mar - Apr;30(2):87-93. doi: 10.1016/j.neucir.2018.02.005. Epub 2018 Apr 3.
Impact factor:
Publication type: Paper in national publication
Authors: Arikan, Fuat; Banos-Carrasco, Pilar; Fonseca, Lino; Gandara-Sabatini, Dario; Najarro-Quispe, Rafael; Rodriguez-Hernandez, Ana; Torne, Ramon et al.
DOI: 10.1016/j.neucir.2018.02.005

The Sport Concussion Assessment Tool (SCAT2) for evaluating civilian mild traumatic brain injury. A pilot normative study.

PMID: 30785950
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Feb 20;14(2):e0212541. doi: 10.1371/journal.pone.0212541. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Castro, Lidia; Cevallos, Mauricio; Gandara, Dario; Pacios, Maria E; Poca, Maria A; Radoi, Andreea; Sahuquillo, Juan et al.
DOI: 10.1371/journal.pone.0212541

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma.

PMID: 30733620
Journal: NATURE
Year: 2019
Reference: Nature. 2019 Feb;566(7745):E13. doi: 10.1038/s41586-019-0959-z.
Impact factor:
Publication type: Letter or abstract
Authors: Admon, Arie; Britten, Cedrik M; Bukur, Valesca; Bunse, Lukas; Capper, David; Castle, John C; Derhovanessian, Evelyna; Dietrich, Pierre-Yves; Dorner, Sonja; Dutoit, Valerie et al.
DOI: 10.1038/s41586-019-0959-z

Blog

News

The goal is to test a low-cost, easy-to-use and non-invasive monitor, which will serve to control intracranial pressure (PICO) values, which will help to control and treat different acute brain pathologies.

The new tool will improve patient care and allow early detection of complications, as the hospital previously did not have a specific form.

Entre els projectes es troben 12 investigacions on participen investigadors i investigadores de Vall d’Hebron.

Rates

Check the current rates for the LUMINEX MAGPIX service offered by the Neurotraumatology and Neurosurgery Research Unit (UNINN).