Skip to main content

Pneumology

The group’s basic and clinical research activity, above all, surrounds the fields of inflammation and repair, respiratory insufficiency and tissue hypoxia, and these fields complement one another and are connected through the study of conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, infections, transplants, pulmonary hypertension or sleep-related breathing disorders.

The group has an experimental research laboratory and a clinical research and clinical trial unit. It is made up of professionals from different specialties (pulmonologists, biologists, nurses, laboratory technicians, physiotherapists etc.). This multidisciplinary team provides an added value to the group and guarantees the existence of the critical mass necessary to carry out scientific projects.

Our group is a node that belongs to the CIBERES network (CIBER for respiratory diseases) and also works in collaboration with groups of the highest national and international prestige.

Publications

Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial.

PMID: 35144989
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2022
Reference: Eur Respir J. 2022 Mar 10;59(3). pii: 13993003.03036-2021. doi: 10.1183/13993003.03036-2021. Print 2022 Mar.
Impact factor: 16.671
Publication type: Letter whit IF
Authors: Agusti, Alvar; Munoz, Xavier; Romero-Mesones, Christian; Sibila, Oriol; Lopez-Giraldo, Alejandra; Moral, Vicente Plaza; Curto, Elena; Echazarreta, Andres L; Marquez, Silvana E; Pascual-Guardia, Sergi et al.
DOI: 10.1183/13993003.03036-2021

Multi-ancestry genome-wide association study of asthma exacerbations.

PMID: 35754128
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2022
Reference: Pediatr Allergy Immunol. 2022 Jun;33(6):e13802. doi: 10.1111/pai.13802.
Impact factor: 6.377
Publication type: Paper in international publication
Authors: Herrera-Luis, Esther; Ortega, Victor E; Sio, Yang Yie; Gorenjak, Mario; Espuela-Ortiz, Antonio; Lethem, Ryan; Vijverberg, Susanne J; Forno, Erick; Yan, Qi; Jorgensen, Andrea L et al.
DOI: 10.1111/pai.13802

Early outcomes in adults hospitalized with severe SARS-CoV-2 infection receiving tocilizumab.

PMID: 35755602
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin. 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcle.2021.06.023. Epub 2022 Jun 18.
Impact factor: 1.725
Publication type: Paper in international publication
Authors: Sellares-Nadal, Julia; Almirante, Benito; Guillen-Del-Castillo, Alfredo; Sampol, Julia; Augustin, Salvador; Bosch-Nicolau, Pau; Monforte-Pallares, Arnau; Sempere-Gonzalez, Abiu; Eremiev-Eremiev, Simeon; Miarons, Marta et al.
DOI: 10.1016/j.medcle.2021.06.023

Lung transplantation for acute respiratory distress syndrome - a retrospective European Cohort Study.

PMID: 34824051
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2022
Reference: Eur Respir J. 2022 Jun 30;59(6). pii: 13993003.02078-2021. doi: 10.1183/13993003.02078-2021. Print 2022 Jun.
Impact factor: 16.671
Publication type: Paper in international publication
Authors: Gottlieb, Jens; Lepper, Philipp M; Berastegui, Cristina; Montull, Beatriz; Hoetzenecker, Konrad; Tikkanen, Jussi; le Pavec, Jerome; Verschuuren, Erik; Sandhaus, Tim; Haneya, Assad et al.
DOI: 10.1183/13993003.02078-2021

Can we Train the Immune System of Patients With Cystic Fibrosis?

PMID: 35699016
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):708-710. doi: 10.1016/j.arbr.2020.10.016.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Assante, Giulio, Martinez-Gallo, Monica, Traversi, Letizia, Tur-Torres, Jordi, Romero Mesones, Christian Eduardo, Chang-Macchiu, Patricia, Alvarez, Antoni, Clofent Alarcon, David, Polverino, Eva, Torres-Sierra, Sandra et al.
DOI: 10.1016/j.arbr.2020.10.016

Peribronchovascular emphysema. The Macklin effect.

PMID: 35699007
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):697. doi: 10.1016/j.arbr.2021.09.001. Epub 2021 Sep 20.
Impact factor: 4.872
Publication type: Paper in international publication
Authors: Villar, Ana, Granados, Galo, Ferreiro, Antia et al.
DOI: 10.1016/j.arbr.2021.09.001

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry.

PMID: 33540340
Journal: RESPIRATORY MEDICINE
Year: 2021
Reference: Respir Med. 2021 Mar;178:106220. doi: 10.1016/j.rmed.2020.106220. Epub 2020 Nov 12.
Impact factor: 3.415
Publication type: Paper in international publication
Authors: Ulrich, Silvia, Gomez Sanchez, Miguel-Angel, Humbert, Marc, Pittrow, David, Simonneau, Gerald, Gall, Henning, Grunig, Ekkehard, Klose, Hans, Halank, Michael, Langleben, David et al.
DOI: 10.1016/j.rmed.2020.106220

Management of drug toxicity in M. avium complex pulmonary disease - an expert panel survey.

PMID: 32910814
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2021
Reference: Clin Infect Dis. 2021 Jul 1;73(1):e256-e259. doi: 10.1093/cid/ciaa1361.
Impact factor: 8.313
Publication type: Paper in international publication
Authors: Wagner, Dirk, van Ingen, Jakko, Aliberti, Stefano, Andrejak, Claire, Chalmers, James D, Codecasa, Luigi R, Daley, Charles L, Hasegawa, Naoki, Griffith, David E, Hoefsloot, Wouter et al.
DOI: 10.1093/cid/ciaa1361

The Importance of Reference Centers and Registries for Rare Diseases: The Example of Alpha-1 Antitrypsin Deficiency.

PMID: 32791925
Journal: COPD-Journal of Chronic Obstructive Pulmonary Disease
Year: 2020
Reference: COPD. 2020 Aug;17(4):346-354. doi: 10.1080/15412555.2020.1795824.
Impact factor: 2.5
Publication type: Paper in international publication
Authors: Miravitlles, Marc, Nunez, Alexa, Torres-Duran, Maria, Casas-Maldonado, Francisco, Rodriguez-Hermosa, Juan Luis, Lopez-Campos, Jose Luis, Calle, Myriam, Rodriguez, Esther, Esquinas, Cristina, Barrecheguren, Miriam et al.
DOI: 10.1080/15412555.2020.1795824

Diagnostic benefits of adding EspC, EspF and Rv2348-B to the QuantiFERON Gold In-tube antigen combination.

PMID: 32764560
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Aug 6;10(1):13234. doi: 10.1038/s41598-020-70204-w.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Millet, J P, Villar-Hernandez, R, Blauenfeldt, T, Garcia-Garcia, E, Muriel-Moreno, B, De Souza-Galvao, M L, Ruiz-Manzano, J, Pilarte, J, Jimenez, M A, Centeno, C et al.
DOI: 10.1038/s41598-020-70204-w

Tuberculosis Following Lung Transplantation. A 27-Year Spanish Multicenter Experience. Incidence, Presentation, Prevention and Treatment with Rifampicin.

PMID: 31771919
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Aug;56(8):493-498. doi: 10.1016/j.arbres.2019.10.013. Epub 2019 Nov 23.
Impact factor: 4.957
Publication type: Paper in national publication
Authors: Sole, Amparo, Part-Lopez, Mar, Saez, Berta, Laporta, Rosalia, Anguera, Gabriel, Cuesta, Victor Mora, De Pablo, Alicia, Canyada-Martinez, Antonio J, Pastor, Amparo, Gil, Ana et al.
DOI: 10.1016/j.arbres.2019.10.013

Evaluation of the Integrated Tuberculosis Research Program Sponsored by the Spanish Society of Pulmonology and Thoracic Surgery: 11 Years on.

PMID: 31780285
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Aug;56(8):483-492. doi: 10.1016/j.arbres.2019.10.006. Epub 2019 Nov 25.
Impact factor: 4.957
Publication type: Paper in national publication
Authors: Bustamante, A, Calpe, J L, Canas, F, Casas, F, Casas, X, Cases, E, Castrodeza, R, Cebrian, J J, Ciruelos, J E, Delgado, A E et al.
DOI: 10.1016/j.arbres.2019.10.006

The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) ERS Clinical Research Collaboration.

PMID: 30498055
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2018
Reference: Eur Respir J. 2018 Nov 29;52(5). pii: 52/5/1802074. doi: 10.1183/13993003.02074-2018. Print 2018 Nov.
Impact factor: 12.242
Publication type: Editorail in international publication
Authors: Polverino, Eva, Chalmers, James D, Altenburg, Josje, Shteinberg, Michal, Goeminne, Pieter C, Welte, Tobias, Shoemark, Amelia, Almagro, Marta, Blasi, Francesco, Aliberti, Stefano et al.
DOI: 10.1183/13993003.02074-2018

Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp.

PMID: 30455865
Journal: Clinical and Translational Allergy
Year: 2018
Reference: Clin Transl Allergy. 2018 Nov 9;8:46. doi: 10.1186/s13601-018-0232-9. eCollection 2018.
Impact factor: 3.539
Publication type: Paper in international publication
Authors: Cruz, M J, Amengual, M J, Munoz, X, Sogo, A et al.
DOI: 10.1186/s13601-018-0232-9

Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management.

PMID: 30419907
Journal: RESPIRATORY RESEARCH
Year: 2018
Reference: Respir Res. 2018 Nov 12;19(1):219. doi: 10.1186/s12931-018-0923-8.
Impact factor: 3.751
Publication type: Paper in international publication
Authors: Gonzalez-Granado, Luis Ignacio, Martin, Carlos, Rodriguez-Gallego, Carlos, Sanchez-Ramon, Silvia, Group, Lung Id-Signal, de Gracia, Javier, Soler-Palacin, Pere et al.
DOI: 10.1186/s12931-018-0923-8

Correction: Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness.

PMID: 30419005
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Nov 12;13(11):e0207586. doi: 10.1371/journal.pone.0207586. eCollection 2018.
Impact factor: 2.766
Publication type: Letter or abstract
Authors: Esteller, Manel, Llatjos, Roger, Varela, Mar, Lopez, Jose Ignacio, Garcia, Nadia, Extremera, Ana I, Guma, Anna, Ortega, Raul, Pla, Maria Jesus, Fernandez, Adela et al.
DOI: 10.1371/journal.pone.0207586

Pulmonary disease by non-tuberculous mycobacteria - clinical management, unmet needs and future perspectives.

PMID: 28967797
Journal: Expert Review of Respiratory Medicine
Year: 2017
Reference: Expert Rev Respir Med. 2017 Dec;11(12):977-989. doi: 10.1080/17476348.2017.1386563. Epub 2017 Oct 10.
Impact factor: 2.432
Publication type: Paper in international publication
Authors: Diel, Roland, Jenkins, Stephen G, Loebinger, Michael R, Codecasa, Luigi R, Hoefsloot, Wouter, Larsson, Lars-Olof, Polverino, Eva et al.
DOI: 10.1080/17476348.2017.1386563

Fascin-1 is released from proximal tubular cells in response to calcineurin inhibitors (CNIs) and correlates with isometric vacuolization in kidney transplanted patients.

PMID: 28979691
Journal: American Journal of Translational Research
Year: 2017
Reference: Am J Transl Res. 2017 Sep 15;9(9):4173-4183. eCollection 2017.
Impact factor: 2.829
Publication type: Paper in international publication
Authors: Meseguer, Anna, Jacobs-Cacha, Conxita, Torres, Irina B, Lopez-Hellin, Joan, Cantarell, Carme, Azancot, Maria A, Roman, Antonio, Moreso, Francesc, Seron, Daniel, Sarro, Eduard et al.
DOI:

Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Type 2 Diabetic Patients.

PMID: 28945872
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2017
Reference: J Clin Endocrinol Metab. 2017 Nov 1;102(11):4109-4116. doi: 10.1210/jc.2017-00913.
Impact factor: 5.455
Publication type: Paper in international publication
Authors: Ciudin, Andreea, Gutierrez, Liliana, Hernandez, Cristina, Simo, Rafael, Hernandez, Marta, Seminario, Asuncion, Sanchez, Enric, Munoz, Xavier, Lopez-Cano, Carolina, Lecube, Albert et al.
DOI: 10.1210/jc.2017-00913

Acute exacerbations of COPD: risk factors for failure and relapse.

PMID: 28932112
Journal: International Journal of Chronic Obstructive Pulmonary Disease
Year: 2017
Reference: Int J Chron Obstruct Pulmon Dis. 2017 Sep 8;12:2687-2693. doi: 10.2147/COPD.S145253. eCollection 2017.
Impact factor: 3.157
Publication type: Review in international publication
Authors: Rogliani, Paola, Mantero, Marco, Crisafulli, Ernesto, Guerrero, Monica, Gramegna, Andrea, Cazzola, Mario, Blasi, Francesco, Polverino, Eva, Di Pasquale, Marta et al.
DOI: 10.2147/COPD.S145253

Blog

News

The EXPOSIM project will investigate the impact of environmental stressors such as pollution, noise and aeroallergens on immune-mediated diseases.

This recognition highlights both his career and the level of respiratory research in Spain.

The ERS Awards recognize outstanding members for their exceptional contributions in the field of respiratory medicine.

EXIMIOUS

EXIMIOUS (Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome), un projecte finançat per la Unió Europea que engloba 15 organitzacions de 7 països europeus.

EXIMIOUS té com a objectiu estudiar l’exposoma, és a dir, l’exposició a factors ambientals al llarg de la vida, per entendre la seva relació amb les malalties immunomediades, com ara les malalties autoimmunes o les al·lèrgies. Des del VHIR està liderat per la Dra. M Jesús Cruz i el seu equip de Pneumologia.