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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Publications

Diagnosing, managing and preventing anaphylaxis: systematic review.

PMID: 32880997
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 May;76(5):1493-1506. doi: 10.1111/all.14580. Epub 2020 Sep 29.
Impact factor: 13.146
Publication type: Review in international publication
Authors: Regent, Lynne, Sanchez, Angel, Vlieg-Boerstra, Berber, Roberts, Graham, Oude Elberink, Hanneke, Michaelis, Louise J, Jensen, Britt, de Silva, Debra, Singh, Chris, Muraro, Antonella et al.
DOI: 10.1111/all.14580

Food-dependent NSAID-induced hypersensitivity reactions (FDNIH): unraveling the clinical features and risk factors.

PMID: 33289951
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 May;76(5):1480-1492. doi: 10.1111/all.14689. Epub 2020 Dec 22.
Impact factor: 13.146
Publication type: Paper in international publication
Authors: Sanchez-Lopez, Jaime, Araujo, Giovanna, Cardona, Victoria, Garcia-Moral, Alba, Casas-Saucedo, Rocio, Guilarte, Mar, Jose Torres, Maria, Dona, Inmaculada, Picado, Cesar, Pascal, Mariona et al.
DOI: 10.1111/all.14689

The Scleromyositis Phenotype. Lessons from a multicenter international cohort of anti-PM/Scl-positive patients.

PMID: 33983413
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Nov 3;60(11):4956-4957. doi: 10.1093/rheumatology/keab433.
Impact factor: 7.58
Publication type: Editorail in international publication
Authors: Selva-O'Callaghan, Albert, Simeon-Aznar, Carmen Pilar et al.
DOI: 10.1093/rheumatology/keab433

Digital technology for anaphylaxis management impact on patient behaviour. A randomised clinical Trial.

PMID: 33043475
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 May;76(5):1507-1516. doi: 10.1111/all.14626. Epub 2020 Nov 4.
Impact factor: 13.146
Publication type: Paper in international publication
Authors: Galvan-Blasco, Paula, Sala-Cunill, Anna, Luengo, Olga, Curran, Adrian, Moreno, Nuria, Labrador-Horrillo, Moises, Guilarte, Mar, Gonzalez-Medina, Monica, Victoria, Cardona et al.
DOI: 10.1111/all.14626

Delayed drug hypersensitivity to bortezomib: desensitization and tolerance to its analogue carfilzomib.

PMID: 30738005
Journal: ALLERGY
Year: 2019
Reference: Allergy. 2019 Jul;74(7):1384-1386. doi: 10.1111/all.13735. Epub 2019 Mar 14.
Impact factor: 6.771
Publication type: Letter whit IF
Authors: Gil-Serrano, Ingrid Johana, Galvan-Blasco, Paula, Guilarte, Mar, Cardona, Victoria, Labrador-Horrillo, Moises, Sala-Cunill, Anna, Luengo, Olga et al.
DOI: 10.1111/all.13735

Discoidin domain receptor 1 gene variants are associated with decreased white matter fractional anisotropy and decreased processing speed in schizophrenia.

PMID: 30597424
Journal: JOURNAL OF PSYCHIATRIC RESEARCH
Year: 2019
Reference: J Psychiatr Res. 2019 Mar;110:74-82. doi: 10.1016/j.jpsychires.2018.12.021. Epub 2018 Dec 24.
Impact factor: 3.917
Publication type: Paper in international publication
Authors: Gas, Cinta, Canales-Rodriguez, Erick Jorge, Radua, Joaquim, Abasolo, Nerea, Cortes, Maria Jose, Salvado, Ester, Muntane, Gerard, Aleman-Gomez, Yasser, Julia, Toni, Marsal, Sara et al.
DOI: 10.1016/j.jpsychires.2018.12.021

Psychometric properties of the Spanish version of the once-daily Urticaria Activity Score (UAS) in patients with chronic spontaneous urticaria managed in clinical practice (the EVALUAS study).

PMID: 30704532
Journal: Health and Quality of Life Outcomes
Year: 2019
Reference: Health Qual Life Outcomes. 2019 Jan 31;17(1):23. doi: 10.1186/s12955-019-1087-z.
Impact factor: 2.318
Publication type: Paper in international publication
Authors: Ferrer, Marta, Jauregui, Ignacio, Gimenez-Arnau, Ana, Bartra, Joan, Labrador-Horrillo, Moises, de Frutos, Javier Ortiz, Silvestre, Juan Francisco, Sastre, Joaquin, Velasco, Manuel, Valero, Antonio et al.
DOI: 10.1186/s12955-019-1087-z

IgE-mediated sensitization to galactose-alpha-1,3-galactose (alpha-gal) in urticaria and anaphylaxis in Spain: geographical variations and risk factors.

PMID: 30676319
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2019
Reference: J Investig Allergol Clin Immunol. 2019;29(6):436-443. doi: 10.18176/jiaci.0373. Epub 2019 Jan 24.
Impact factor: 3.802
Publication type: Paper in international publication
Authors: Mateo-Borrega, M B, Garcia, B, Hernando Larramendi, C, Azofra, J, Gonzalez-Mancebo, E, Alvarado, M I, Nunez-Orjales, R, Dieguez, M C, Guilarte, M, Soriano-Galarraga, A M et al.
DOI: 10.18176/jiaci.0373

Blog

News

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.