About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 34136127 Journal: Clinical and Translational Allergy Year: 2021 Reference: Clin Transl Allergy. 2021 Jun 9;11(4):e12014. doi: 10.1002/clt2.12014. eCollection 2021 Jun. Impact factor: 5.871 Publication type: Review in international publication Authors: Casale, Tomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M, Chkhartishvili, Ekaterine, Chu, Derek K, Cirule, Ieva, Cruz, Alvaro A, Czarlewski, Wienczyslawa, Del Giacco, Stefano, Carreiro-Martins, Pedro et al. DOI: 10.1002/clt2.12014
PMID: 34142390 Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY Year: 2021 Reference: Pediatr Allergy Immunol. 2021 Nov;32(8):1730-1742. doi: 10.1111/pai.13578. Epub 2021 Jul 21. Impact factor: 6.377 Publication type: Paper in international publication Authors: Tanno, Luciana Kase, Clark, Evangeline, Mamodaly, Myriam, Cardona, Victoria, Ebisawa, Motohiro, Asontegui, Ignacio, Sanchez-Borges, Mario, Santos, Alexandra F, Fiocchi, Alessandro, Worm, Margitta et al. DOI: 10.1111/pai.13578
PMID: 34071326 Journal: SENSORS Year: 2021 Reference: Sensors (Basel). 2021 May 28;21(11). pii: s21113746. doi: 10.3390/s21113746. Impact factor: 3.576 Publication type: Paper in international publication Authors: Capdevila, Lluis, Castro-Marrero, Jesus, Alegre, Jose, Ramos-Castro, Juan, Escorihuela, Rosa M et al. DOI: 10.3390/s21113746
PMID: 34069603 Journal: Medicina-Lithuania Year: 2021 Reference: Medicina (Kaunas). 2021 May 19;57(5). pii: medicina57050510. doi: 10.3390/medicina57050510. Impact factor: 2.43 Publication type: Paper in international publication Authors: Nacul, Luis, Authier, Francois Jerome, Scheibenbogen, Carmen, Lorusso, Lorenzo, Helland, Ingrid Bergliot, Martin, Jose Alegre, Sirbu, Carmen Adella, Mengshoel, Anne Marit, Polo, Olli, Behrends, Uta et al. DOI: 10.3390/medicina57050510
PMID: 30861336 Journal: Arthritis & Rheumatology Year: 2019 Reference: Arthritis Rheumatol. 2019 Aug;71(8):1371-1376. doi: 10.1002/art.40883. Epub 2019 Jun 18. Impact factor: 9.002 Publication type: Paper in international publication Authors: Pinal-Fernandez, Iago, Amici, David R, Parks, Cassie A, Derfoul, Assia, Casal-Dominguez, Maria, Pak, Katherine, Yeker, Richard, Plotz, Paul, Milisenda, Jose C, Selva-O'Callaghan, Albert et al. DOI: 10.1002/art.40883
PMID: 30847342 Journal: Frontiers in Medicine Year: 2019 Reference: Front Med (Lausanne). 2019 Feb 21;6:28. doi: 10.3389/fmed.2019.00028. eCollection 2019. Impact factor: 3.113 Publication type: Paper in international publication Authors: Veronez, Camila Lopes, Aabom, Anne, Martin, Renan Paulo, Filippelli-Silva, Rafael, Goncalves, Rozana Fatima, Nicolicht, Priscila, Mendes, Agatha Ribeiro, Da Silva, Jane, Guilarte, Mar, Grumach, Anete Sevciovic et al. DOI: 10.3389/fmed.2019.00028
PMID: 30808881 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Feb 26;9(1):2777. doi: 10.1038/s41598-019-39113-5. Impact factor: 4.011 Publication type: Paper in international publication Authors: Espinosa, Gerard, Burillo-Sanz, Sergio, Montes-Cano, Marco-Antonio, Garcia-Lozano, Jose-Raul, Olivas-Martinez, Israel, Ortego-Centeno, Norberto, Garcia-Hernandez, Francisco-Jose, Julia, Maria Rosa, Solans, Roser, Blanco, Ricardo et al. DOI: 10.1038/s41598-019-39113-5
PMID: 30789234 Journal: RHEUMATOLOGY Year: 2019 Reference: Rheumatology (Oxford). 2019 Jul 1;58(7):1299-1301. doi: 10.1093/rheumatology/kez015. Impact factor: 5.149 Publication type: Paper in international publication Authors: Simeon, Carmen Pilar, Carreria, Patricia, Ortego-Centeno, Norberto, Vicente, Esther, Worthington, Jane, Herrick, Ariane L, Martin, Javier, Teruel, Maria, Lopez-Isac, Elena, Duffus, Kate et al. DOI: 10.1093/rheumatology/kez015
PMID: 27999855 Journal: Journal of Nutrition Health & Aging Year: 2017 Reference: J Nutr Health Aging. 2017;21(1):92-104. doi: 10.1007/s12603-016-0803-1. Impact factor: 2.772 Publication type: Paper in international publication Authors: Siciliano, P, Goswami, N, Guldemond, N A, Henderson, D, Hinkema, M J, Liotta, G, Mair, A, Molloy, W, Monaco, A, Monsonis-Paya, I et al. DOI: 10.1007/s12603-016-0803-1
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
