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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Publications

PD-L1 testing based on SP142 antibody in metastatic triple-negative breast cancer: summary of an expert round-table discussion.

PMID: 33289433
Journal: Future Oncology
Year: 2021
Reference: Future Oncol. 2021 Apr;17(10):1209-1218. doi: 10.2217/fon-2020-1100. Epub 2020 Dec 8.
Impact factor: 3.404
Publication type: Review in international publication
Authors: Peiro, Gloria, Peg, Vicente, Lopez-Garcia, Maria Angeles, Comerma, Laura, Suarez-Gauthier, Ana, Ruiz, Irune, Rojo, Federico, Lopez, Angel Concha, Garcia-Caballero, Tomas et al.
DOI: 10.2217/fon-2020-1100

Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future.

PMID: 33399086
Journal: ESMO Open
Year: 2021
Reference: ESMO Open. 2021 Feb;6(1):100024. doi: 10.1016/j.esmoop.2020.100024. Epub 2020 Dec 2.
Impact factor: 6.54
Publication type: Paper in international publication
Authors: Pelosi, G, Hofman, P, Ilie, M, Chamorey, E, Brest, P, Schiappa, R, Nakache, V, Antoine, M, Garcia-Martos, M, Gibault, L et al.
DOI: 10.1016/j.esmoop.2020.100024

Secondary syphilis with liver involvement in a liver transplant recipient.

PMID: 32738832
Journal: Transplant Infectious Disease
Year: 2021
Reference: Transpl Infect Dis. 2021 Feb;23(1):e13431. doi: 10.1111/tid.13431. Epub 2020 Aug 16.
Impact factor: 2.228
Publication type: Review in international publication
Authors: Ferrandiz-Pulido, Carla, Ferrer, Berta, Salcedo, Maria Teresa, Velasco, Marta, Len, Oscar, Castells, Lluis et al.
DOI: 10.1111/tid.13431

[Update of the recommendations for the determination of biomarkers in colorectal carcinoma. National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology].

PMID: 33455693
Journal: Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de
Year: 2021
Reference: Rev Esp Patol. 2021 Jan-Mar;54(1):41-54. doi: 10.1016/j.patol.2020.07.004. Epub 2020 Oct 16.
Impact factor: 0
Publication type: Review in national publication
Authors: Perez-Segura, Pedro, Salazar, Ramon, Vera, Ruth, Garcia-Alfonso, Pilar, Garcia-Foncillas, Jesus, Garcia-Carbonero, Rocio, Musulen, Eva, Navarro, Samuel, Cuatrecasas, Miriam, Hernandez-Losa, Javier et al.
DOI: 10.1016/j.patol.2020.07.004

Evaluation of the intraoperative human papilloma virus test as a marker of early cure at 12 months after electrosurgical excision procedure in patients with cervical High Grade Squamous Intraepithelial Lesion: a prospective cohort study.

PMID: 31502397
Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Year: 2020
Reference: BJOG. 2020 Jan;127(1):99-105. doi: 10.1111/1471-0528.15932. Epub 2019 Sep 25.
Impact factor: 4.663
Publication type: Paper in international publication
Authors: Garcia, A, Centeno, C, Gil-Moreno, A, Dinares, C, Hernandez, J, Cabrera, S, Rabasa, J, Bradbury, M, Sanchez-Iglesias, J L, Guerrero, D et al.
DOI: 10.1111/1471-0528.15932

Blog

News

On World Cancer Research Day, we highlight the oncology research model of the Vall d'Hebron Campus that allows laboratory results to be transferred as quickly as possible to clinical practice.

Vall d’Hebron ha celebrat avui la Jornada del Dia Mundial contra el Càncer, una malaltia cada cop més freqüent que patiran al llarg de la vida un de cada dos homes i una de cada tres dones del nostre entorn.

The multidisciplinary paper on papillary thyroid cancer has been considered the best original article of 2021 in the journal Endocrinología, Diabetes y Nutrición

Job offers

Investigador/a en formació
Start date:
08/09/2014
End date:
14/09/2014
Document: Download
Tècnic/a Superior de Recerca projecte 'Estudio de modelos murinos de tumores humanos'
Start date:
03/07/2014
End date:
09/07/2014
Llicenciat/da en Ciències de la Salut
Start date:
20/06/2014
End date:
27/06/2014

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates 2016-2020

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