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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Publications

Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors central nervous system involvement of B-cell lymphomas.

PMID: 32079701
Journal: HAEMATOLOGICA
Year: 2021
Reference: Haematologica. 2021 Feb 1;106(2):513-521. doi: 10.3324/haematol.2019.241208.
Impact factor: 9.941
Publication type: Paper in international publication
Authors: Raheja, Priyanka, Carpio, Cecilia, Rubio-Perez, Carlota, Tazon-Vega, Barbara, Palacio, Carlos, Carabia, Julia, Jimenez, Isabel, Nieto, Juan C, Montoro, Julia, Martinez-Ricarte, Francisco et al.
DOI: 10.3324/haematol.2019.241208

Spiral Arteries in Second Trimester of Pregnancy: When Is It Possible to Define Expected Physiological Remodeling as Abnormal?

PMID: 33237514
Journal: Reproductive Sciences
Year: 2021
Reference: Reprod Sci. 2021 Apr;28(4):1185-1193. doi: 10.1007/s43032-020-00403-3. Epub 2020 Nov 25.
Impact factor: 3.06
Publication type: Paper in international publication
Authors: Franco, Jorge Andres, Rodriguez, Jorge Luis, Vargas, Magda Jimena, Aula-Olivar, Ana, Quintero, Laura, Ramon Y Cajal, Santiago, Garrido, Marta, Olaya-C, Mercedes et al.
DOI: 10.1007/s43032-020-00403-3

PD-L1 testing based on SP142 antibody in metastatic triple-negative breast cancer: summary of an expert round-table discussion.

PMID: 33289433
Journal: Future Oncology
Year: 2021
Reference: Future Oncol. 2021 Apr;17(10):1209-1218. doi: 10.2217/fon-2020-1100. Epub 2020 Dec 8.
Impact factor: 3.404
Publication type: Review in international publication
Authors: Peiro, Gloria, Peg, Vicente, Lopez-Garcia, Maria Angeles, Comerma, Laura, Suarez-Gauthier, Ana, Ruiz, Irune, Rojo, Federico, Lopez, Angel Concha, Garcia-Caballero, Tomas et al.
DOI: 10.2217/fon-2020-1100

Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future.

PMID: 33399086
Journal: ESMO Open
Year: 2021
Reference: ESMO Open. 2021 Feb;6(1):100024. doi: 10.1016/j.esmoop.2020.100024. Epub 2020 Dec 2.
Impact factor: 6.54
Publication type: Paper in international publication
Authors: Pelosi, G, Hofman, P, Ilie, M, Chamorey, E, Brest, P, Schiappa, R, Nakache, V, Antoine, M, Garcia-Martos, M, Gibault, L et al.
DOI: 10.1016/j.esmoop.2020.100024

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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